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The map label for this gene is zraS [C]

Identifier: 126447073

GI number: 126447073

Start: 2340630

End: 2342912

Strand: Direct

Name: zraS [C]

Synonym: BMA10247_A2403

Alternate gene names: 126447073

Gene position: 2340630-2342912 (Clockwise)

Preceding gene: 126447809

Following gene: 126446159

Centisome position: 99.49

GC content: 68.24

Gene sequence:

>2283_bases
ATGACGCCCGAACGGCCCGACGCTTCACGCTCGACATCGCCCGACAACGACGATTGGGAGGACGATGCTTCGTTCGCGCC
CGGCGCGCCGGAGCACGATTTCGCGGTGCGGCGCGTGACGCTCATCGTGATGCTCGTCGCCGCGATCGTGCTGCCGTGCG
TATACGTCGCGGTGATGGCTTACAACGACATGCGCACGCGCGAGGCCACCGCGCGCGACGTGACGATGCGCACCGTGCGC
GTCGCCGAGGAGCATGCGCTGAAAGTATTCGATCTGTCGGAGACGCTCGACGCGCGGATCGTCGATCTCGTGCAGGATCT
CGACGATGCCGCGGTGCGCAATGCCGAGGCCGACATCCATGATGCGCTCAACACGATCGGCGGCGGCTATCCGCAGGTCG
CCTCGGTGTCGATCTTCGGCGCGAGCGGGATGCTGCTCGCGAACAGCCTCTATTACCCGGCGCCGTATGCGTCGATCGCG
GAGCGCGACGATTTCGTCGGCATCCGCGACGGCAAGGTGATCGAGCACATCTCGCGCGTGATGCCGGGGCCGCTGAAGGC
GGCGAATCCGGGGCCCGTGTTCAATACGGGCGTCGCGCGGCGCCATAGCGACGGCACGTTCGCGGGGATGGTGTCGATCG
CGCTGAAGTCTTCGTATTTCAACGCGTTCTATCGCGATCTGCTCGGCGGCGCCGACGCGCCGATGTCGATGGCGCTCACG
CGCACCGACGGCGCCGTGCTCGCGTCGTATCCGCCCGCGTCGCGCGGCGCGCCGGACGACGCCGCATCGCAGGCCGACAG
CGCGAACCCGTTCGGCGGCGCGCAAGGCGATCAGCATGCGGGCATCGTGCGCGTGAAGCGCGACGGCGACAGCGAGATCG
TCGCGTACCGGCAGGTCGGCAGCTATCCCGTGTTCGTATCGTGCGCGTACCGCACGTCGGCGATCCGTCATGCGTGGTAC
GAGCACCTGAGCGTGCTGTTCATCTCGATGTTCGCGCCGTCCGCCGCGCTGTGGGGCGTGATCTGGCTGTCGCTCAAGCG
GCTGCGCGCGGAGGAGCAGGCCTGGGAGCGCTGGCAGGCGGAGGCGTCGATGCGGCGCTCGATCGAATCGGCGTACCGGC
AGTCGCGCAAGATGGAGGCGCTCGGCAACCTGGTCGGCAGCGTCGCGCACGATTTCAACAACCTGCTGATGATCATCTCG
AGCAACGTGCAGATCGCGCGGCGGCGCGGCGTTCAGCATCTGGACACCGAGCTCGCCGCGATCGAGCGCGCGCTGAAGAA
CGGCCAGTCGCTCACGCGCCAGTTGCTGGGTGTCGCACGCAAGCAGCCGCTGCGCAGCGAGACGATCGACATCGCGCACT
GGCTCGCGTCGTGCCGCGAGTTGCTGAAGACGTCGCTCGGCTCGAAATCGACGCTCGCCGTCGACACGCAGCTCGACCTG
TGGCCCGTGCGCGTCGACGTCGCGGAGCTCGAGCTCGCGGTGATCAATCTCGCGGTCAACGCCCGCGACGCGATGCCGCA
GGGCGGGCGCTTCAAGATCAGCGCGCACAACATCACGTTCCGCCGCGAGGACGGCTTTCCGCTGACGGGCGACTTCGTGC
AGATCTCGGTCGAGGATACCGGCCTCGGCATGTCGCCCGAGGTGCTCGCGCGCGCGTTCGAGCCGCTTTTCACGACGAAG
GCGAAGGGGATGGGCACGGGCCTCGGACTGCCGCAGGTATTCGCGTTCTGCGAGCGCTCCGGGGGGCTCGCGACGATCGA
CAGCGAAGTGGGCGCGGGCACGTCGGTGCGGCTCTACCTGCCGCGCACGACCGACGCGGTGCCACCCGTCGACGCGCCCA
ACGCCGTCGACAATCTCGCCGCCTCGACGCCTGCGGGGCTGCGAATCCTGCTCGTCGAGGACAATGGTGAAGTCGCGGCG
GGCACCGAGGCGCTGCTCGAGCTGCTCGGCCATCAGGTCACGCACGCGCCGAACGCGGACGACGCGTTGCGCATGCTGAA
CGCCGCAGGCGCCGAGCCAGGCGCGCCGGGCACGTTCGATCTCGTGATCTCGGACATCCACATGCCGGGCACGATCAACG
GGATCGATCTCGCGGAGGCGATCGAACGCGGCGACATGAAGCTGCCGGTGATTCTCGTCACCGGCTACGCGGAGGAGTTC
GACCGGACGCGCCGCGTCCATGCGCGGTTGCTGTCGAAACCGTTCGACATCGCGCTGCTCGACGACTTGCTGCAGAAGAT
CCAGCACGAGCGCGACGCGCGGCTCGCGGGGCATGAGGATTGA

Upstream 100 bases:

>100_bases
GGAAAACCGGCCCCGCGCAAGCTCCGTGCCCCGCGCGGATCACGCGTGCGCGACTCGTTTATGATGCCGATCAATCCCTT
TGCGCATTCGTTCGCCCACC

Downstream 100 bases:

>100_bases
AGAGGTAGGGGTGGTTGGCGGTCGCTTCGGTTGGGTGAGGAAAGGCCGTGGGGGCGGTGGTTGAGGGCTGTGGGGGACTC
GGTCTGGTTGGGAAGAGGCT

Product: sensor histidine kinase/response regulator

Products: NA

Alternate protein names: Blue-light-activated histidine kinase; Response regulator [H]

Number of amino acids: Translated: 760; Mature: 759

Protein sequence:

>760_residues
MTPERPDASRSTSPDNDDWEDDASFAPGAPEHDFAVRRVTLIVMLVAAIVLPCVYVAVMAYNDMRTREATARDVTMRTVR
VAEEHALKVFDLSETLDARIVDLVQDLDDAAVRNAEADIHDALNTIGGGYPQVASVSIFGASGMLLANSLYYPAPYASIA
ERDDFVGIRDGKVIEHISRVMPGPLKAANPGPVFNTGVARRHSDGTFAGMVSIALKSSYFNAFYRDLLGGADAPMSMALT
RTDGAVLASYPPASRGAPDDAASQADSANPFGGAQGDQHAGIVRVKRDGDSEIVAYRQVGSYPVFVSCAYRTSAIRHAWY
EHLSVLFISMFAPSAALWGVIWLSLKRLRAEEQAWERWQAEASMRRSIESAYRQSRKMEALGNLVGSVAHDFNNLLMIIS
SNVQIARRRGVQHLDTELAAIERALKNGQSLTRQLLGVARKQPLRSETIDIAHWLASCRELLKTSLGSKSTLAVDTQLDL
WPVRVDVAELELAVINLAVNARDAMPQGGRFKISAHNITFRREDGFPLTGDFVQISVEDTGLGMSPEVLARAFEPLFTTK
AKGMGTGLGLPQVFAFCERSGGLATIDSEVGAGTSVRLYLPRTTDAVPPVDAPNAVDNLAASTPAGLRILLVEDNGEVAA
GTEALLELLGHQVTHAPNADDALRMLNAAGAEPGAPGTFDLVISDIHMPGTINGIDLAEAIERGDMKLPVILVTGYAEEF
DRTRRVHARLLSKPFDIALLDDLLQKIQHERDARLAGHED

Sequences:

>Translated_760_residues
MTPERPDASRSTSPDNDDWEDDASFAPGAPEHDFAVRRVTLIVMLVAAIVLPCVYVAVMAYNDMRTREATARDVTMRTVR
VAEEHALKVFDLSETLDARIVDLVQDLDDAAVRNAEADIHDALNTIGGGYPQVASVSIFGASGMLLANSLYYPAPYASIA
ERDDFVGIRDGKVIEHISRVMPGPLKAANPGPVFNTGVARRHSDGTFAGMVSIALKSSYFNAFYRDLLGGADAPMSMALT
RTDGAVLASYPPASRGAPDDAASQADSANPFGGAQGDQHAGIVRVKRDGDSEIVAYRQVGSYPVFVSCAYRTSAIRHAWY
EHLSVLFISMFAPSAALWGVIWLSLKRLRAEEQAWERWQAEASMRRSIESAYRQSRKMEALGNLVGSVAHDFNNLLMIIS
SNVQIARRRGVQHLDTELAAIERALKNGQSLTRQLLGVARKQPLRSETIDIAHWLASCRELLKTSLGSKSTLAVDTQLDL
WPVRVDVAELELAVINLAVNARDAMPQGGRFKISAHNITFRREDGFPLTGDFVQISVEDTGLGMSPEVLARAFEPLFTTK
AKGMGTGLGLPQVFAFCERSGGLATIDSEVGAGTSVRLYLPRTTDAVPPVDAPNAVDNLAASTPAGLRILLVEDNGEVAA
GTEALLELLGHQVTHAPNADDALRMLNAAGAEPGAPGTFDLVISDIHMPGTINGIDLAEAIERGDMKLPVILVTGYAEEF
DRTRRVHARLLSKPFDIALLDDLLQKIQHERDARLAGHED
>Mature_759_residues
TPERPDASRSTSPDNDDWEDDASFAPGAPEHDFAVRRVTLIVMLVAAIVLPCVYVAVMAYNDMRTREATARDVTMRTVRV
AEEHALKVFDLSETLDARIVDLVQDLDDAAVRNAEADIHDALNTIGGGYPQVASVSIFGASGMLLANSLYYPAPYASIAE
RDDFVGIRDGKVIEHISRVMPGPLKAANPGPVFNTGVARRHSDGTFAGMVSIALKSSYFNAFYRDLLGGADAPMSMALTR
TDGAVLASYPPASRGAPDDAASQADSANPFGGAQGDQHAGIVRVKRDGDSEIVAYRQVGSYPVFVSCAYRTSAIRHAWYE
HLSVLFISMFAPSAALWGVIWLSLKRLRAEEQAWERWQAEASMRRSIESAYRQSRKMEALGNLVGSVAHDFNNLLMIISS
NVQIARRRGVQHLDTELAAIERALKNGQSLTRQLLGVARKQPLRSETIDIAHWLASCRELLKTSLGSKSTLAVDTQLDLW
PVRVDVAELELAVINLAVNARDAMPQGGRFKISAHNITFRREDGFPLTGDFVQISVEDTGLGMSPEVLARAFEPLFTTKA
KGMGTGLGLPQVFAFCERSGGLATIDSEVGAGTSVRLYLPRTTDAVPPVDAPNAVDNLAASTPAGLRILLVEDNGEVAAG
TEALLELLGHQVTHAPNADDALRMLNAAGAEPGAPGTFDLVISDIHMPGTINGIDLAEAIERGDMKLPVILVTGYAEEFD
RTRRVHARLLSKPFDIALLDDLLQKIQHERDARLAGHED

Specific function: Photosensitive kinase and response regulator that is involved in increased bacterial virulence upon exposure to light [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=242, Percent_Identity=28.5123966942149, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI1788549, Length=245, Percent_Identity=26.1224489795918, Blast_Score=78, Evalue=3e-15,
Organism=Escherichia coli, GI87081816, Length=244, Percent_Identity=30.327868852459, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI48994928, Length=237, Percent_Identity=28.6919831223629, Blast_Score=67, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 82236; Mature: 82105

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPERPDASRSTSPDNDDWEDDASFAPGAPEHDFAVRRVTLIVMLVAAIVLPCVYVAVMA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YNDMRTREATARDVTMRTVRVAEEHALKVFDLSETLDARIVDLVQDLDDAAVRNAEADIH
HCCHHHHHHHHHHHHHHHHHHHHHHCEEEEECHHHHHHHHHHHHHHHHHHHHHCCCHHHH
DALNTIGGGYPQVASVSIFGASGMLLANSLYYPAPYASIAERDDFVGIRDGKVIEHISRV
HHHHHHCCCCCCCEEEEEECCCCHHHHCCCCCCCCCHHHHCCCCEECCCCCHHHHHHHHH
MPGPLKAANPGPVFNTGVARRHSDGTFAGMVSIALKSSYFNAFYRDLLGGADAPMSMALT
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEE
RTDGAVLASYPPASRGAPDDAASQADSANPFGGAQGDQHAGIVRVKRDGDSEIVAYRQVG
ECCCEEEECCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCEEEEEECCCCCEEEEECCC
SYPVFVSCAYRTSAIRHAWYEHLSVLFISMFAPSAALWGVIWLSLKRLRAEEQAWERWQA
CCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
EASMRRSIESAYRQSRKMEALGNLVGSVAHDFNNLLMIISSNVQIARRRGVQHLDTELAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCHHHHHHCCCHHHHHHHHH
IERALKNGQSLTRQLLGVARKQPLRSETIDIAHWLASCRELLKTSLGSKSTLAVDTQLDL
HHHHHHCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCE
WPVRVDVAELELAVINLAVNARDAMPQGGRFKISAHNITFRREDGFPLTGDFVQISVEDT
EEEEEEHHHHEEEEEEEEEEHHHCCCCCCEEEEEECEEEEEECCCCCCCCCEEEEEEECC
GLGMSPEVLARAFEPLFTTKAKGMGTGLGLPQVFAFCERSGGLATIDSEVGAGTSVRLYL
CCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCEEEECCCCCCCCEEEEEE
PRTTDAVPPVDAPNAVDNLAASTPAGLRILLVEDNGEVAAGTEALLELLGHQVTHAPNAD
CCCCCCCCCCCCCCHHHHHHCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCHH
DALRMLNAAGAEPGAPGTFDLVISDIHMPGTINGIDLAEAIERGDMKLPVILVTGYAEEF
HHHHHHHHCCCCCCCCCEEEEEEEEECCCCCCCCCHHHHHHHCCCCCEEEEEEECCHHHH
DRTRRVHARLLSKPFDIALLDDLLQKIQHERDARLAGHED
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
TPERPDASRSTSPDNDDWEDDASFAPGAPEHDFAVRRVTLIVMLVAAIVLPCVYVAVMA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YNDMRTREATARDVTMRTVRVAEEHALKVFDLSETLDARIVDLVQDLDDAAVRNAEADIH
HCCHHHHHHHHHHHHHHHHHHHHHHCEEEEECHHHHHHHHHHHHHHHHHHHHHCCCHHHH
DALNTIGGGYPQVASVSIFGASGMLLANSLYYPAPYASIAERDDFVGIRDGKVIEHISRV
HHHHHHCCCCCCCEEEEEECCCCHHHHCCCCCCCCCHHHHCCCCEECCCCCHHHHHHHHH
MPGPLKAANPGPVFNTGVARRHSDGTFAGMVSIALKSSYFNAFYRDLLGGADAPMSMALT
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEE
RTDGAVLASYPPASRGAPDDAASQADSANPFGGAQGDQHAGIVRVKRDGDSEIVAYRQVG
ECCCEEEECCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCEEEEEECCCCCEEEEECCC
SYPVFVSCAYRTSAIRHAWYEHLSVLFISMFAPSAALWGVIWLSLKRLRAEEQAWERWQA
CCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
EASMRRSIESAYRQSRKMEALGNLVGSVAHDFNNLLMIISSNVQIARRRGVQHLDTELAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCHHHHHHCCCHHHHHHHHH
IERALKNGQSLTRQLLGVARKQPLRSETIDIAHWLASCRELLKTSLGSKSTLAVDTQLDL
HHHHHHCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCE
WPVRVDVAELELAVINLAVNARDAMPQGGRFKISAHNITFRREDGFPLTGDFVQISVEDT
EEEEEEHHHHEEEEEEEEEEHHHCCCCCCEEEEEECEEEEEECCCCCCCCCEEEEEEECC
GLGMSPEVLARAFEPLFTTKAKGMGTGLGLPQVFAFCERSGGLATIDSEVGAGTSVRLYL
CCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCEEEECCCCCCCCEEEEEE
PRTTDAVPPVDAPNAVDNLAASTPAGLRILLVEDNGEVAAGTEALLELLGHQVTHAPNAD
CCCCCCCCCCCCCCHHHHHHCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCHH
DALRMLNAAGAEPGAPGTFDLVISDIHMPGTINGIDLAEAIERGDMKLPVILVTGYAEEF
HHHHHHHHCCCCCCCCCEEEEEEEEECCCCCCCCCHHHHHHHCCCCCEEEEEEECCHHHH
DRTRRVHARLLSKPFDIALLDDLLQKIQHERDARLAGHED
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA