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The map label for this gene is cyp137 [H]

Identifier: 126447071

GI number: 126447071

Start: 22942

End: 24348

Strand: Direct

Name: cyp137 [H]

Synonym: BMA10247_A0029

Alternate gene names: 126447071

Gene position: 22942-24348 (Clockwise)

Preceding gene: 126445939

Following gene: 126447278

Centisome position: 0.98

GC content: 65.25

Gene sequence:

>1407_bases
ATGAATGGCCTCCCTCTGTCGCTTCCGCGAGTCGACAGCACCGATTCGCTCTTTGCGGATCCGCTCGCTTTTCTCGCACG
AGCGCGCGCGCAATGCGGCGACGTCTTCGTGCTGCGGGAGCACGGTCCGATTTTTTCTCGCGCGAGCGATTGCAGCGGCG
TGATCGCCGTGTTCGGCGAACATCGGCTTCGACAAGTCTTGACCGAGACGGACACCTTCGCGCTGCCGATGTCAGCGGCG
GCGAAGATGGCGTTGCCGAAGAATCTGGTCAACCTCAACCGCGGCTTGCACAGCATGCGCGAGCCGGAGCACGGCCGGCA
CAAGCGCCTCCTGACGGGAACGGCCAACCGCGCGCTGTTCGACGCGCATCGATCCGGAATGCAAACGGATTTGAGCCGCT
TTTGCGAAATGCTGAACGGGGACGGCCGGATTTCCGTCGTGAGCCGAATGCGCGAGCTGACAGCCAAGTTGGCGTCCCGT
CTTTTTCTTGGGCCGCAGTGTGAGGAGGATGCCGAACTGACGTTTCTGCTAAGCGCGTATTTCACGTTGCGGCGCGAGGC
GTCTTCGCCCAACGCGCACGATCCGTTGCAGTACCGGGACGCGCTGATCGGCGCCGGGCGGCAACTCGATCGCGCGTTGC
GGGCGCGGATCCGGCGGTATCGAAAGGCGCCCGCCGGCGAGTGCGCGGGGCTGCTCCAGCGGCTGGCGACGGCCGGCCAG
CCGGGTTCGCCCGCGCTTTCCGAGGATGAGATCGTCGGCCACGCCAACGTGATGTTTGTGTCGAGCACGGAGCCGGTGGC
GATATCGCTGGCGTGGCTGCTGCTCGTTCTGTCGCAGTTGCCCGATCTGCGGCGTGCGCTTCGCGCGGAAAGCGCCGCCC
GCGCATCGTCGCCGGCTTCGCCGTACGACGCGCCATTGCTCGAGCGCGTCATCAACGAGACGCTTCGGCTCCTGACGCCC
AACGCGCTGATGGTCCGCGCCACGACGCAGGCGGTTTCGTTGCAAGGCGTCGCGCTTCCCGCGCGCTGCGAGATTGTCGT
GTGCCCGTTCCTCGTGCACCGCGAGGCCAACGCGTTTGCGCGCCCGCATGCATTCTTGCCGTCCCGATGGGAGACGGCGA
GGCCGTCGCCGTACGAGTATTTTCCATTCGGCGCCGGCGGCCATTTCTGCGCGGGGCGGAATCTCGCGCTGTCGCTGATT
GGCGAAGTGCTGTCGACGCTGCTATCGCGATTCGATTTCGTTTTGGATATCGAACAGTTTATCGACTGGCGCATTCATAT
CATGCTGATGCCGAAAGGCGACCCGACGCTCACGGCGCACCCCGTCGATGAACGCCGCGACACGCCGTCGCCGAAATGGC
GCGGGCCTGTCGCCGAGCTGTTCCATTTCGCGCCGGGGCTTTCTTGA

Upstream 100 bases:

>100_bases
GGCGGCTTCGGAAGACGTGATACTGTGACGGCAGCCATGCTGTAGCGATCAACCGGCGTAGCCACGATCGGCACGAATCG
TTCACGGACACAGCGCGCAA

Downstream 100 bases:

>100_bases
CATTTACCGGGGCGCATCCTTTAATCAGAAGCAAATCGGCATGCACACCCGACGGGATTTTTTCGGTCATCGATTCGCAT
GGCGATTTTCGGGGGTTATT

Product: cytochrome P450-related protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 468; Mature: 468

Protein sequence:

>468_residues
MNGLPLSLPRVDSTDSLFADPLAFLARARAQCGDVFVLREHGPIFSRASDCSGVIAVFGEHRLRQVLTETDTFALPMSAA
AKMALPKNLVNLNRGLHSMREPEHGRHKRLLTGTANRALFDAHRSGMQTDLSRFCEMLNGDGRISVVSRMRELTAKLASR
LFLGPQCEEDAELTFLLSAYFTLRREASSPNAHDPLQYRDALIGAGRQLDRALRARIRRYRKAPAGECAGLLQRLATAGQ
PGSPALSEDEIVGHANVMFVSSTEPVAISLAWLLLVLSQLPDLRRALRAESAARASSPASPYDAPLLERVINETLRLLTP
NALMVRATTQAVSLQGVALPARCEIVVCPFLVHREANAFARPHAFLPSRWETARPSPYEYFPFGAGGHFCAGRNLALSLI
GEVLSTLLSRFDFVLDIEQFIDWRIHIMLMPKGDPTLTAHPVDERRDTPSPKWRGPVAELFHFAPGLS

Sequences:

>Translated_468_residues
MNGLPLSLPRVDSTDSLFADPLAFLARARAQCGDVFVLREHGPIFSRASDCSGVIAVFGEHRLRQVLTETDTFALPMSAA
AKMALPKNLVNLNRGLHSMREPEHGRHKRLLTGTANRALFDAHRSGMQTDLSRFCEMLNGDGRISVVSRMRELTAKLASR
LFLGPQCEEDAELTFLLSAYFTLRREASSPNAHDPLQYRDALIGAGRQLDRALRARIRRYRKAPAGECAGLLQRLATAGQ
PGSPALSEDEIVGHANVMFVSSTEPVAISLAWLLLVLSQLPDLRRALRAESAARASSPASPYDAPLLERVINETLRLLTP
NALMVRATTQAVSLQGVALPARCEIVVCPFLVHREANAFARPHAFLPSRWETARPSPYEYFPFGAGGHFCAGRNLALSLI
GEVLSTLLSRFDFVLDIEQFIDWRIHIMLMPKGDPTLTAHPVDERRDTPSPKWRGPVAELFHFAPGLS
>Mature_468_residues
MNGLPLSLPRVDSTDSLFADPLAFLARARAQCGDVFVLREHGPIFSRASDCSGVIAVFGEHRLRQVLTETDTFALPMSAA
AKMALPKNLVNLNRGLHSMREPEHGRHKRLLTGTANRALFDAHRSGMQTDLSRFCEMLNGDGRISVVSRMRELTAKLASR
LFLGPQCEEDAELTFLLSAYFTLRREASSPNAHDPLQYRDALIGAGRQLDRALRARIRRYRKAPAGECAGLLQRLATAGQ
PGSPALSEDEIVGHANVMFVSSTEPVAISLAWLLLVLSQLPDLRRALRAESAARASSPASPYDAPLLERVINETLRLLTP
NALMVRATTQAVSLQGVALPARCEIVVCPFLVHREANAFARPHAFLPSRWETARPSPYEYFPFGAGGHFCAGRNLALSLI
GEVLSTLLSRFDFVLDIEQFIDWRIHIMLMPKGDPTLTAHPVDERRDTPSPKWRGPVAELFHFAPGLS

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome P450 family [H]

Homologues:

Organism=Homo sapiens, GI4503243, Length=410, Percent_Identity=23.4146341463415, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI225903399, Length=323, Percent_Identity=25.077399380805, Blast_Score=86, Evalue=6e-17,
Organism=Homo sapiens, GI13435386, Length=177, Percent_Identity=29.3785310734463, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI4503211, Length=201, Percent_Identity=27.8606965174129, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI4503231, Length=222, Percent_Identity=25.6756756756757, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI4503213, Length=176, Percent_Identity=28.4090909090909, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI16933533, Length=213, Percent_Identity=24.4131455399061, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI262290932, Length=177, Percent_Identity=27.1186440677966, Blast_Score=76, Evalue=5e-14,
Organism=Homo sapiens, GI12383060, Length=214, Percent_Identity=24.7663551401869, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI187960086, Length=175, Percent_Identity=28.5714285714286, Blast_Score=72, Evalue=8e-13,
Organism=Homo sapiens, GI310125128, Length=411, Percent_Identity=23.1143552311436, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI14550409, Length=411, Percent_Identity=23.1143552311436, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI310125130, Length=341, Percent_Identity=24.633431085044, Blast_Score=70, Evalue=5e-12,
Organism=Homo sapiens, GI190570174, Length=341, Percent_Identity=24.633431085044, Blast_Score=70, Evalue=5e-12,
Organism=Homo sapiens, GI261278370, Length=182, Percent_Identity=27.4725274725275, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI261278372, Length=182, Percent_Identity=27.4725274725275, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI195972896, Length=182, Percent_Identity=27.4725274725275, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI195972898, Length=182, Percent_Identity=27.4725274725275, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI167466231, Length=201, Percent_Identity=24.3781094527363, Blast_Score=66, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI71982956, Length=201, Percent_Identity=22.8855721393035, Blast_Score=72, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI71985409, Length=182, Percent_Identity=23.6263736263736, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI221330299, Length=178, Percent_Identity=28.0898876404494, Blast_Score=82, Evalue=8e-16,
Organism=Drosophila melanogaster, GI24641483, Length=204, Percent_Identity=28.921568627451, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI28571357, Length=204, Percent_Identity=28.921568627451, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI17933518, Length=194, Percent_Identity=26.2886597938144, Blast_Score=72, Evalue=8e-13,
Organism=Drosophila melanogaster, GI21355669, Length=222, Percent_Identity=24.7747747747748, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI19921824, Length=241, Percent_Identity=26.1410788381743, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI17864130, Length=192, Percent_Identity=24.4791666666667, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001128
- InterPro:   IPR017972
- InterPro:   IPR002401 [H]

Pfam domain/function: PF00067 p450 [H]

EC number: NA

Molecular weight: Translated: 51592; Mature: 51592

Theoretical pI: Translated: 8.76; Mature: 8.76

Prosite motif: PS00086 CYTOCHROME_P450

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNGLPLSLPRVDSTDSLFADPLAFLARARAQCGDVFVLREHGPIFSRASDCSGVIAVFGE
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCHHHHHHHH
HRLRQVLTETDTFALPMSAAAKMALPKNLVNLNRGLHSMREPEHGRHKRLLTGTANRALF
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCHHHHH
DAHRSGMQTDLSRFCEMLNGDGRISVVSRMRELTAKLASRLFLGPQCEEDAELTFLLSAY
HHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
FTLRREASSPNAHDPLQYRDALIGAGRQLDRALRARIRRYRKAPAGECAGLLQRLATAGQ
HHHHHHCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCC
PGSPALSEDEIVGHANVMFVSSTEPVAISLAWLLLVLSQLPDLRRALRAESAARASSPAS
CCCCCCCCCCEECCCEEEEEECCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCC
PYDAPLLERVINETLRLLTPNALMVRATTQAVSLQGVALPARCEIVVCPFLVHREANAFA
CCCHHHHHHHHHHHHHHHCCCEEEEEEEHHHHEECCEECCCCCCEEECCHHHHCCCCHHC
RPHAFLPSRWETARPSPYEYFPFGAGGHFCAGRNLALSLIGEVLSTLLSRFDFVLDIEQF
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
IDWRIHIMLMPKGDPTLTAHPVDERRDTPSPKWRGPVAELFHFAPGLS
CCEEEEEEEEECCCCCEEECCCHHCCCCCCCCCCCCHHHHHHHCCCCC
>Mature Secondary Structure
MNGLPLSLPRVDSTDSLFADPLAFLARARAQCGDVFVLREHGPIFSRASDCSGVIAVFGE
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCHHHHHHHH
HRLRQVLTETDTFALPMSAAAKMALPKNLVNLNRGLHSMREPEHGRHKRLLTGTANRALF
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCHHHHH
DAHRSGMQTDLSRFCEMLNGDGRISVVSRMRELTAKLASRLFLGPQCEEDAELTFLLSAY
HHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
FTLRREASSPNAHDPLQYRDALIGAGRQLDRALRARIRRYRKAPAGECAGLLQRLATAGQ
HHHHHHCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCC
PGSPALSEDEIVGHANVMFVSSTEPVAISLAWLLLVLSQLPDLRRALRAESAARASSPAS
CCCCCCCCCCEECCCEEEEEECCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCC
PYDAPLLERVINETLRLLTPNALMVRATTQAVSLQGVALPARCEIVVCPFLVHREANAFA
CCCHHHHHHHHHHHHHHHCCCEEEEEEEHHHHEECCEECCCCCCEEECCHHHHCCCCHHC
RPHAFLPSRWETARPSPYEYFPFGAGGHFCAGRNLALSLIGEVLSTLLSRFDFVLDIEQF
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
IDWRIHIMLMPKGDPTLTAHPVDERRDTPSPKWRGPVAELFHFAPGLS
CCEEEEEEEEECCCCCEEECCCHHCCCCCCCCCCCCHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]