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The map label for this gene is ggt [H]

Identifier: 126447031

GI number: 126447031

Start: 1297234

End: 1298955

Strand: Reverse

Name: ggt [H]

Synonym: BMA10247_A1328

Alternate gene names: 126447031

Gene position: 1298955-1297234 (Counterclockwise)

Preceding gene: 126447154

Following gene: 126447342

Centisome position: 55.21

GC content: 66.55

Gene sequence:

>1722_bases
ATGAATGCAACGAATCGTTTCAAGTCGACGGTGCTCGCCGCGCTCGTGAGCTCGGCGCTCGCCGGTTTTCTGCCGAGCGC
GCCCGCCCATGCGAAGGGCCCGCAGCAGCGCGTCGTGCTGGACGGCTCGGCCGTCGCGGTCGCCGACAAGTACAGCGCCG
ACGCGGCCGAGGAGATCTTCAGGCAGGGCGGCAACGCGGTCGACGCCGCGGTCGCGATCGCCTTCACGCTCGCCGTCACC
TATCCGGAGGCGGGCAACATCGGCGGCGGCGGCTTCATGACCGTCTACATGGGCGGCAAGCCGTACTTTCTCGACTATCG
CGAGCGCGCGCCGCTCGCCGCGACGAAGGACATGTATCTCGACAAGGACGGCAACGTCGTCAAGGGCATGAGCCTGTACG
GCGATCGCGCGGTCGGCGTGCCCGGCACGGTGGCCGGGATGTGGGAGGCGCAGAAGCGCTTCGGCAAGCTGAAGTGGAAG
CAGGTGATCGCGCCCGCGATCCGTTACGCGCGCGACGGCTTCGTTGTCGACGAGCAGCTCGCGCAGCGTGGCGTCGACGC
GTCGAAGGAGTTCGGCGGCAAGACGAACTTCGATCAATACTTCAGCGGCCTGAAGGCGGGCGCGACCTTCAAGCAGCCGG
AGCTCGCGGCGGTGCTCGCGCGCATCGCGAACGATGGCGCGAAGGATTTCTACGACGGCAAGACGGCCGACCTGATCGCC
GCATCGATGAAGAAGGGCGGCGGCCTGATCACGAAGCAGGATCTCGTCCAGTACAAGGCGGTGTGGCGCCAGCCGGTCCA
GGCGAACTGGAACGGCTATCGCGTGATCACCGCGCCGCCGCCGAGCTCGGGCGGCATCGGCCTCGTGCAGTTGCTGACGA
TGAAGGCGGACCGCAAGGCCGATTTCGACGGCGTCGCGCTCAATTCGCCGCAATACGTGCATCTGATCGCCGAGATCGAG
AAGCGCGTGTTCGCCGATCGCGCGCAGTACCTCGGCGATCCGGATTTCTACAAGGTGCCCGTCGCGCAGTTGACCGACGC
CGCGTACATCGCGAAGCGCGCGGCCGAGGTGAATCCCGAGAAGCCGTCCGACACGAAGAGCGTGCTGCCGGGCCTCGGCA
CGTCGATGCCGGAGAAGGCCGAGACGACGCATTTCTCCGTCGTCGACAAGTGGGGCAACGCGGTGTCGAACACGTACACG
ATCAACGGCTACTTCGGCTCGGGCGTCGTCGCCGAAGGCACGGGCATCGTGCTCAACGACGAGATGGACGATTTCTCCGC
GAAGCCGGGCGTCGCCAACATGTTCGGCGTCGTCGGCAGCGACGCGAACGCGATCGAGCCGAAGAAGCGGCCGCTGTCGT
CGATGTCGCCGACGGTCCTCACGAAGGACGGCAAGGTCGCGCTCGTGATCGGCACGCCGGGCGGCTCGCGGATCTTCACG
TCGATCTTCCAGGTGATCACGAACCTGTACGACTTCAAGATGCCGCTGAAGGACGCGGTCGGCGCGATGCGCTTTCACCA
CCAGCTGCTGCCGCCGAACACGATCTTCTGGGAGCCGTACCACTCGATCGACGGCGAGCTGGCGAAGGGCATCGAGGCGA
AGGGCTACACGCTCAAGGGCCAGGATTTCAGCGGCGACATCCAGGCGATCCGGATCGACGGCAAGACGCCCGAGGCGGTG
TCCGATCCGCGCGGCCGCGGCGTGTCGCGCGTGATCCGGTAA

Upstream 100 bases:

>100_bases
ACGAAACCCCATTTTTGTATACGCGCGCGGCCATGCTATAAGCCTATTCGTCGGACTTTCGTGCCACAATTAGCAAGGAG
ATCGAAATGGGAGACATCCA

Downstream 100 bases:

>100_bases
GCGTGGCGCGCCGGCGTGCCGAAGCCGCGGCGCGCCGGCGCGAGCACGAACGGGCCGGCGAAAGCGCGGCGCGCTGACCG
TGGCGCGCCGCGCTTTCGTG

Product: gamma-glutamyltranspeptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 573; Mature: 573

Protein sequence:

>573_residues
MNATNRFKSTVLAALVSSALAGFLPSAPAHAKGPQQRVVLDGSAVAVADKYSADAAEEIFRQGGNAVDAAVAIAFTLAVT
YPEAGNIGGGGFMTVYMGGKPYFLDYRERAPLAATKDMYLDKDGNVVKGMSLYGDRAVGVPGTVAGMWEAQKRFGKLKWK
QVIAPAIRYARDGFVVDEQLAQRGVDASKEFGGKTNFDQYFSGLKAGATFKQPELAAVLARIANDGAKDFYDGKTADLIA
ASMKKGGGLITKQDLVQYKAVWRQPVQANWNGYRVITAPPPSSGGIGLVQLLTMKADRKADFDGVALNSPQYVHLIAEIE
KRVFADRAQYLGDPDFYKVPVAQLTDAAYIAKRAAEVNPEKPSDTKSVLPGLGTSMPEKAETTHFSVVDKWGNAVSNTYT
INGYFGSGVVAEGTGIVLNDEMDDFSAKPGVANMFGVVGSDANAIEPKKRPLSSMSPTVLTKDGKVALVIGTPGGSRIFT
SIFQVITNLYDFKMPLKDAVGAMRFHHQLLPPNTIFWEPYHSIDGELAKGIEAKGYTLKGQDFSGDIQAIRIDGKTPEAV
SDPRGRGVSRVIR

Sequences:

>Translated_573_residues
MNATNRFKSTVLAALVSSALAGFLPSAPAHAKGPQQRVVLDGSAVAVADKYSADAAEEIFRQGGNAVDAAVAIAFTLAVT
YPEAGNIGGGGFMTVYMGGKPYFLDYRERAPLAATKDMYLDKDGNVVKGMSLYGDRAVGVPGTVAGMWEAQKRFGKLKWK
QVIAPAIRYARDGFVVDEQLAQRGVDASKEFGGKTNFDQYFSGLKAGATFKQPELAAVLARIANDGAKDFYDGKTADLIA
ASMKKGGGLITKQDLVQYKAVWRQPVQANWNGYRVITAPPPSSGGIGLVQLLTMKADRKADFDGVALNSPQYVHLIAEIE
KRVFADRAQYLGDPDFYKVPVAQLTDAAYIAKRAAEVNPEKPSDTKSVLPGLGTSMPEKAETTHFSVVDKWGNAVSNTYT
INGYFGSGVVAEGTGIVLNDEMDDFSAKPGVANMFGVVGSDANAIEPKKRPLSSMSPTVLTKDGKVALVIGTPGGSRIFT
SIFQVITNLYDFKMPLKDAVGAMRFHHQLLPPNTIFWEPYHSIDGELAKGIEAKGYTLKGQDFSGDIQAIRIDGKTPEAV
SDPRGRGVSRVIR
>Mature_573_residues
MNATNRFKSTVLAALVSSALAGFLPSAPAHAKGPQQRVVLDGSAVAVADKYSADAAEEIFRQGGNAVDAAVAIAFTLAVT
YPEAGNIGGGGFMTVYMGGKPYFLDYRERAPLAATKDMYLDKDGNVVKGMSLYGDRAVGVPGTVAGMWEAQKRFGKLKWK
QVIAPAIRYARDGFVVDEQLAQRGVDASKEFGGKTNFDQYFSGLKAGATFKQPELAAVLARIANDGAKDFYDGKTADLIA
ASMKKGGGLITKQDLVQYKAVWRQPVQANWNGYRVITAPPPSSGGIGLVQLLTMKADRKADFDGVALNSPQYVHLIAEIE
KRVFADRAQYLGDPDFYKVPVAQLTDAAYIAKRAAEVNPEKPSDTKSVLPGLGTSMPEKAETTHFSVVDKWGNAVSNTYT
INGYFGSGVVAEGTGIVLNDEMDDFSAKPGVANMFGVVGSDANAIEPKKRPLSSMSPTVLTKDGKVALVIGTPGGSRIFT
SIFQVITNLYDFKMPLKDAVGAMRFHHQLLPPNTIFWEPYHSIDGELAKGIEAKGYTLKGQDFSGDIQAIRIDGKTPEAV
SDPRGRGVSRVIR

Specific function: GGT PLAYS A KEY ROLE IN THE GAMMA-GLUTAMYL CYCLE, A PATHWAY FOR THE SYNTHESIS AND DEGRADATION OF GLUTATHIONE. [C]

COG id: COG0405

COG function: function code E; Gamma-glutamyltransferase

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gamma-glutamyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI73915092, Length=561, Percent_Identity=32.620320855615, Blast_Score=224, Evalue=2e-58,
Organism=Homo sapiens, GI73915090, Length=561, Percent_Identity=32.620320855615, Blast_Score=224, Evalue=2e-58,
Organism=Homo sapiens, GI73915096, Length=561, Percent_Identity=32.620320855615, Blast_Score=224, Evalue=2e-58,
Organism=Homo sapiens, GI73915094, Length=561, Percent_Identity=32.620320855615, Blast_Score=224, Evalue=2e-58,
Organism=Homo sapiens, GI113429324, Length=562, Percent_Identity=31.3167259786477, Blast_Score=196, Evalue=6e-50,
Organism=Homo sapiens, GI113429326, Length=566, Percent_Identity=30.9187279151943, Blast_Score=193, Evalue=4e-49,
Organism=Homo sapiens, GI109148539, Length=523, Percent_Identity=29.8279158699809, Blast_Score=153, Evalue=3e-37,
Organism=Homo sapiens, GI153266885, Length=548, Percent_Identity=26.6423357664234, Blast_Score=153, Evalue=5e-37,
Organism=Homo sapiens, GI153266901, Length=549, Percent_Identity=26.775956284153, Blast_Score=152, Evalue=8e-37,
Organism=Homo sapiens, GI153266907, Length=545, Percent_Identity=25.5045871559633, Blast_Score=140, Evalue=4e-33,
Organism=Homo sapiens, GI30581157, Length=195, Percent_Identity=42.5641025641026, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI30581155, Length=195, Percent_Identity=42.5641025641026, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI218505805, Length=172, Percent_Identity=41.8604651162791, Blast_Score=100, Evalue=7e-21,
Organism=Homo sapiens, GI310124095, Length=194, Percent_Identity=36.5979381443299, Blast_Score=81, Evalue=2e-15,
Organism=Escherichia coli, GI1789856, Length=532, Percent_Identity=45.6766917293233, Blast_Score=422, Evalue=1e-119,
Organism=Caenorhabditis elegans, GI212646519, Length=539, Percent_Identity=35.4359925788497, Blast_Score=258, Evalue=5e-69,
Organism=Caenorhabditis elegans, GI72000294, Length=539, Percent_Identity=35.4359925788497, Blast_Score=258, Evalue=5e-69,
Organism=Caenorhabditis elegans, GI17506189, Length=525, Percent_Identity=33.3333333333333, Blast_Score=218, Evalue=5e-57,
Organism=Caenorhabditis elegans, GI17542894, Length=505, Percent_Identity=33.8613861386139, Blast_Score=218, Evalue=6e-57,
Organism=Caenorhabditis elegans, GI193208247, Length=496, Percent_Identity=32.258064516129, Blast_Score=218, Evalue=8e-57,
Organism=Caenorhabditis elegans, GI193208245, Length=496, Percent_Identity=32.258064516129, Blast_Score=218, Evalue=1e-56,
Organism=Caenorhabditis elegans, GI72001495, Length=226, Percent_Identity=28.7610619469027, Blast_Score=102, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI72001497, Length=245, Percent_Identity=28.9795918367347, Blast_Score=102, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI17564448, Length=417, Percent_Identity=26.1390887290168, Blast_Score=96, Evalue=5e-20,
Organism=Saccharomyces cerevisiae, GI6323330, Length=588, Percent_Identity=31.2925170068027, Blast_Score=168, Evalue=3e-42,
Organism=Drosophila melanogaster, GI18859893, Length=535, Percent_Identity=35.7009345794393, Blast_Score=251, Evalue=8e-67,
Organism=Drosophila melanogaster, GI161077496, Length=543, Percent_Identity=31.1233885819521, Blast_Score=221, Evalue=9e-58,
Organism=Drosophila melanogaster, GI45551474, Length=475, Percent_Identity=31.7894736842105, Blast_Score=200, Evalue=2e-51,
Organism=Drosophila melanogaster, GI24642670, Length=475, Percent_Identity=31.7894736842105, Blast_Score=200, Evalue=2e-51,
Organism=Drosophila melanogaster, GI24642666, Length=475, Percent_Identity=31.7894736842105, Blast_Score=200, Evalue=2e-51,
Organism=Drosophila melanogaster, GI161077880, Length=475, Percent_Identity=31.7894736842105, Blast_Score=200, Evalue=2e-51,
Organism=Drosophila melanogaster, GI161077878, Length=475, Percent_Identity=31.7894736842105, Blast_Score=200, Evalue=3e-51,
Organism=Drosophila melanogaster, GI18859741, Length=544, Percent_Identity=28.4926470588235, Blast_Score=187, Evalue=2e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000101 [H]

Pfam domain/function: PF01019 G_glu_transpept [H]

EC number: =2.3.2.2 [H]

Molecular weight: Translated: 61391; Mature: 61391

Theoretical pI: Translated: 9.41; Mature: 9.41

Prosite motif: PS00462 G_GLU_TRANSPEPTIDASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNATNRFKSTVLAALVSSALAGFLPSAPAHAKGPQQRVVLDGSAVAVADKYSADAAEEIF
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCEEEEECCCCCHHHHHHH
RQGGNAVDAAVAIAFTLAVTYPEAGNIGGGGFMTVYMGGKPYFLDYRERAPLAATKDMYL
HCCCCHHHHHHHHHHHHEEECCCCCCCCCCCEEEEEECCCEEEECHHCCCCCCCCCCEEE
DKDGNVVKGMSLYGDRAVGVPGTVAGMWEAQKRFGKLKWKQVIAPAIRYARDGFVVDEQL
CCCCCEEECCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCEECHHH
AQRGVDASKEFGGKTNFDQYFSGLKAGATFKQPELAAVLARIANDGAKDFYDGKTADLIA
HHCCCCCHHHCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCHHHCCCCHHHHHH
ASMKKGGGLITKQDLVQYKAVWRQPVQANWNGYRVITAPPPSSGGIGLVQLLTMKADRKA
HHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHCCCCC
DFDGVALNSPQYVHLIAEIEKRVFADRAQYLGDPDFYKVPVAQLTDAAYIAKRAAEVNPE
CCCCEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCEECCHHHHHHHHHHHHHHHCCCCC
KPSDTKSVLPGLGTSMPEKAETTHFSVVDKWGNAVSNTYTINGYFGSGVVAEGTGIVLND
CCCCHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCCCCEEEEEEEECCCEEECCCCEEECC
EMDDFSAKPGVANMFGVVGSDANAIEPKKRPLSSMSPTVLTKDGKVALVIGTPGGSRIFT
CCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEECCCCEEEEEECCCCHHHHH
SIFQVITNLYDFKMPLKDAVGAMRFHHQLLPPNTIFWEPYHSIDGELAKGIEAKGYTLKG
HHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCEEECCHHHCCCHHHCCCCCCCEEECC
QDFSGDIQAIRIDGKTPEAVSDPRGRGVSRVIR
CCCCCCEEEEEECCCCCCCCCCCCCCCHHHHCC
>Mature Secondary Structure
MNATNRFKSTVLAALVSSALAGFLPSAPAHAKGPQQRVVLDGSAVAVADKYSADAAEEIF
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCEEEEECCCCCHHHHHHH
RQGGNAVDAAVAIAFTLAVTYPEAGNIGGGGFMTVYMGGKPYFLDYRERAPLAATKDMYL
HCCCCHHHHHHHHHHHHEEECCCCCCCCCCCEEEEEECCCEEEECHHCCCCCCCCCCEEE
DKDGNVVKGMSLYGDRAVGVPGTVAGMWEAQKRFGKLKWKQVIAPAIRYARDGFVVDEQL
CCCCCEEECCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCEECHHH
AQRGVDASKEFGGKTNFDQYFSGLKAGATFKQPELAAVLARIANDGAKDFYDGKTADLIA
HHCCCCCHHHCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCHHHCCCCHHHHHH
ASMKKGGGLITKQDLVQYKAVWRQPVQANWNGYRVITAPPPSSGGIGLVQLLTMKADRKA
HHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHCCCCC
DFDGVALNSPQYVHLIAEIEKRVFADRAQYLGDPDFYKVPVAQLTDAAYIAKRAAEVNPE
CCCCEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCEECCHHHHHHHHHHHHHHHCCCCC
KPSDTKSVLPGLGTSMPEKAETTHFSVVDKWGNAVSNTYTINGYFGSGVVAEGTGIVLND
CCCCHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCCCCEEEEEEEECCCEEECCCCEEECC
EMDDFSAKPGVANMFGVVGSDANAIEPKKRPLSSMSPTVLTKDGKVALVIGTPGGSRIFT
CCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEECCCCEEEEEECCCCHHHHH
SIFQVITNLYDFKMPLKDAVGAMRFHHQLLPPNTIFWEPYHSIDGELAKGIEAKGYTLKG
HHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCEEECCHHHCCCHHHCCCCCCCEEECC
QDFSGDIQAIRIDGKTPEAVSDPRGRGVSRVIR
CCCCCCEEEEEECCCCCCCCCCCCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]