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The map label for this gene is gst-2 [H]

Identifier: 126446856

GI number: 126446856

Start: 105811

End: 106611

Strand: Direct

Name: gst-2 [H]

Synonym: BMA10247_A0125

Alternate gene names: 126446856

Gene position: 105811-106611 (Clockwise)

Preceding gene: 126446762

Following gene: 126447506

Centisome position: 4.5

GC content: 71.29

Gene sequence:

>801_bases
ATGCGGCGCGCCGAGGCCGTGCTTCGGCGCGGTGTCTCGACGCCATGCGCGGCCGTGCCGCCGCAGCGCCGCGTCGTGAC
CTTCCTTGCGTCGTCCGTCGTCGGCGGTTCGTCCGTTGTCCTTCGTGTTCATCCTTCGTTCGAGGAGTGCCGCTCCATGT
CTGCCCACCGCCCGCCTGCCGCGCCGATCCGGCTCCACCGCAGCCCGCTGTCCGGCCACTGCCATCGCGTCGAGCTGTTC
CTGTCGCTGCTCGGCGTGCCTGTCGAATTCGTCGAAGTCGACATGCGGGGCGGCGCGCATCGCCGCCCCGAATTTCTCGC
GCTCAATCCGTTCGGCCAGGTGCCCGTCATCGAGGACGGCGAATGTGTGCTGTTCGATTCGAACGCGATCCTCGTCTACC
TCGCGAAGCGCTACGGCGATCCGTCGTGGCTGCCCGACGATCCGCAAGGCGCGGCCGCCGTGCAGCGCTGGCTGTCGCTC
GCGGCAGGGCCGATCGCGTACGGTGCGGCCGCCGCGCGCCTCGTCACGCTGTTCGGCGCGCCGCTCGATCACGCGGGCGC
GATCGGGATCGCGCGGCGGCTGTTCGACGTGATCGAGCCGCAGCTCGCCGGCAAGCGCTTCGCGACGGGCGAGCATCCGA
CGATCGCCGACGTCGCCGCGTACGCGTATATCGCGCATGCGCCGGAGGGCGGCGTGTCGCTCGATCGGTATCCGAATCTG
CGCGCGTGGCTCGCGCGCATCGAGGCGTTGCCGGGTTTCGTGCCGATGCCGCGAAGCCACGCGGGGCCGCGCGCGGCGTG
A

Upstream 100 bases:

>100_bases
TGGCCCTGTTTGTAGGGGGCAGGTCACATCTTATGCGAACGCGATGCGCACGCTACGCTGCATGTGTCGGCGGCGGGACC
GCCGGTGCGCCGCGCGGCCG

Downstream 100 bases:

>100_bases
TGGGGCTTGATGCTGCGCGATGTGGCGGGATGTCGCGTGATGCGGCCCGACATGACCCGATGCGATTTGACCTGGCTGCG
CGCGGCGTTGCCGGGCGCGG

Product: glutathione S-transferase

Products: HX; R-S-glutathione

Alternate protein names: NA

Number of amino acids: Translated: 266; Mature: 266

Protein sequence:

>266_residues
MRRAEAVLRRGVSTPCAAVPPQRRVVTFLASSVVGGSSVVLRVHPSFEECRSMSAHRPPAAPIRLHRSPLSGHCHRVELF
LSLLGVPVEFVEVDMRGGAHRRPEFLALNPFGQVPVIEDGECVLFDSNAILVYLAKRYGDPSWLPDDPQGAAAVQRWLSL
AAGPIAYGAAAARLVTLFGAPLDHAGAIGIARRLFDVIEPQLAGKRFATGEHPTIADVAAYAYIAHAPEGGVSLDRYPNL
RAWLARIEALPGFVPMPRSHAGPRAA

Sequences:

>Translated_266_residues
MRRAEAVLRRGVSTPCAAVPPQRRVVTFLASSVVGGSSVVLRVHPSFEECRSMSAHRPPAAPIRLHRSPLSGHCHRVELF
LSLLGVPVEFVEVDMRGGAHRRPEFLALNPFGQVPVIEDGECVLFDSNAILVYLAKRYGDPSWLPDDPQGAAAVQRWLSL
AAGPIAYGAAAARLVTLFGAPLDHAGAIGIARRLFDVIEPQLAGKRFATGEHPTIADVAAYAYIAHAPEGGVSLDRYPNL
RAWLARIEALPGFVPMPRSHAGPRAA
>Mature_266_residues
MRRAEAVLRRGVSTPCAAVPPQRRVVTFLASSVVGGSSVVLRVHPSFEECRSMSAHRPPAAPIRLHRSPLSGHCHRVELF
LSLLGVPVEFVEVDMRGGAHRRPEFLALNPFGQVPVIEDGECVLFDSNAILVYLAKRYGDPSWLPDDPQGAAAVQRWLSL
AAGPIAYGAAAARLVTLFGAPLDHAGAIGIARRLFDVIEPQLAGKRFATGEHPTIADVAAYAYIAHAPEGGVSLDRYPNL
RAWLARIEALPGFVPMPRSHAGPRAA

Specific function: Unknown

COG id: COG0625

COG function: function code O; Glutathione S-transferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GST N-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI4504187, Length=192, Percent_Identity=31.25, Blast_Score=81, Evalue=9e-16,
Organism=Homo sapiens, GI124249394, Length=192, Percent_Identity=31.25, Blast_Score=81, Evalue=9e-16,
Organism=Homo sapiens, GI167466164, Length=201, Percent_Identity=28.8557213930348, Blast_Score=77, Evalue=2e-14,
Organism=Escherichia coli, GI1788640, Length=196, Percent_Identity=28.0612244897959, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI87081789, Length=189, Percent_Identity=28.042328042328, Blast_Score=67, Evalue=9e-13,
Organism=Drosophila melanogaster, GI24654965, Length=185, Percent_Identity=34.5945945945946, Blast_Score=90, Evalue=1e-18,
Organism=Drosophila melanogaster, GI19922532, Length=185, Percent_Identity=33.5135135135135, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI20130115, Length=187, Percent_Identity=35.2941176470588, Blast_Score=89, Evalue=4e-18,
Organism=Drosophila melanogaster, GI20130123, Length=199, Percent_Identity=31.1557788944724, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI45549270, Length=199, Percent_Identity=27.6381909547739, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24654992, Length=186, Percent_Identity=32.7956989247312, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24654983, Length=185, Percent_Identity=32.972972972973, Blast_Score=81, Evalue=7e-16,
Organism=Drosophila melanogaster, GI17864594, Length=199, Percent_Identity=26.1306532663317, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI17933730, Length=187, Percent_Identity=25.1336898395722, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24654979, Length=183, Percent_Identity=30.6010928961749, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI221378983, Length=209, Percent_Identity=28.7081339712919, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24646259, Length=188, Percent_Identity=30.3191489361702, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI19922932, Length=179, Percent_Identity=27.9329608938547, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI17864596, Length=178, Percent_Identity=26.9662921348315, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI85725204, Length=194, Percent_Identity=26.8041237113402, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI17737923, Length=194, Percent_Identity=26.8041237113402, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI28571670, Length=176, Percent_Identity=26.7045454545455, Blast_Score=75, Evalue=7e-14,
Organism=Drosophila melanogaster, GI17864592, Length=187, Percent_Identity=26.7379679144385, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI17864598, Length=193, Percent_Identity=26.9430051813472, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI19922526, Length=195, Percent_Identity=28.2051282051282, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24646251, Length=190, Percent_Identity=26.8421052631579, Blast_Score=71, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24654996, Length=180, Percent_Identity=28.3333333333333, Blast_Score=68, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010987
- InterPro:   IPR004045
- InterPro:   IPR017933
- InterPro:   IPR004046
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00043 GST_C; PF02798 GST_N [H]

EC number: 2.5.1.18

Molecular weight: Translated: 28590; Mature: 28590

Theoretical pI: Translated: 9.25; Mature: 9.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRAEAVLRRGVSTPCAAVPPQRRVVTFLASSVVGGSSVVLRVHPSFEECRSMSAHRPPA
CCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCHHHHHCCCCCCCCC
APIRLHRSPLSGHCHRVELFLSLLGVPVEFVEVDMRGGAHRRPEFLALNPFGQVPVIEDG
CCEEEECCCCCCCHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCEEEECCCCCCCEEECC
ECVLFDSNAILVYLAKRYGDPSWLPDDPQGAAAVQRWLSLAAGPIAYGAAAARLVTLFGA
CEEEEECCEEEEEEEHHCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCC
PLDHAGAIGIARRLFDVIEPQLAGKRFATGEHPTIADVAAYAYIAHAPEGGVSLDRYPNL
CCCCCHHHHHHHHHHHHHCHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCH
RAWLARIEALPGFVPMPRSHAGPRAA
HHHHHHHHHCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MRRAEAVLRRGVSTPCAAVPPQRRVVTFLASSVVGGSSVVLRVHPSFEECRSMSAHRPPA
CCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCHHHHHCCCCCCCCC
APIRLHRSPLSGHCHRVELFLSLLGVPVEFVEVDMRGGAHRRPEFLALNPFGQVPVIEDG
CCEEEECCCCCCCHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCEEEECCCCCCCEEECC
ECVLFDSNAILVYLAKRYGDPSWLPDDPQGAAAVQRWLSLAAGPIAYGAAAARLVTLFGA
CEEEEECCEEEEEEEHHCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCC
PLDHAGAIGIARRLFDVIEPQLAGKRFATGEHPTIADVAAYAYIAHAPEGGVSLDRYPNL
CCCCCHHHHHHHHHHHHHCHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCH
RAWLARIEALPGFVPMPRSHAGPRAA
HHHHHHHHHCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: RX; glutathione

Specific reaction: RX + glutathione = HX + R-S-glutathione

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA