Click here to switch to the map view.

The map label for this gene is mcl1 [H]

Identifier: 126446777

GI number: 126446777

Start: 446498

End: 447517

Strand: Reverse

Name: mcl1 [H]

Synonym: BMA10247_A0496

Alternate gene names: 126446777

Gene position: 447517-446498 (Counterclockwise)

Preceding gene: 126446381

Following gene: 126447450

Centisome position: 19.02

GC content: 73.53

Gene sequence:

>1020_bases
ATGTCCGCGCTCACACCCGCAGAAGTGCTGTACGAAGGCGTTGCGCCGCCCGCGATCCTGCCGTGCTGCGATCATTACGC
GGGCAGCGAGAAGCTGATGCTCAAATCGCTCGCGCTGCAGGCCGAGCTCGGTCCCGTCTTCGACATCACGCTCGACTGCG
AGGACGGCGCGGCCGTCGGCCGCGAGGCCGAGCACGCGGCGCGCGTCGCCGCGCTCGTCGGCGGCGAGGCGAACCGCTTC
GGGCGCGTCGGCGTGCGTATCCACGACATTTCCCACCCTCACTGGCGCGACGACGTGCGCGTCGTCCTGCGCGCGGCGCG
CCCGCCCGCGTACCTGACGCTGCCGAAGGTCGGCGGCGCGGCCGACGCGGCCGAGATGTGCGCGTTCATCGAGGCGTCCC
GCGTCGAGCTCGGCATCGCGCAGCCGATCCCCGTCGACGTGCTGATCGAGACGCACGGCGCGCTCGCCGACGCCGCGCGG
ATCGCCGCGCTGCCGATCGTCGCGACCCTGAGCTTCGGCCTGATGGATTTCGTATCCGCGCATCACGGCGCGATTCCGGA
CGACGCGATGCGCGCGCCCGGCCAGTTCGACCACCCGCTCGTGCGCCGCGCGAAGCTCGAGATCGCCGCCGCGTGCCACG
CGCACGGCAAGACGCCGTCGCACAACGTGACGACCGAGGTACGCGACATGCGCGTCGTCGCGAACGACGCGCGCCGCGCC
CGCGAGGAATTCGGCTACACGCGGATGTGGAGCATCCACCCGGCGCAGATCCGCGAGATCGTCGCCGCGTTCGCGCCGCG
CGCGGACGACATCGCGCGCGCGAGCCGCATCCTGCTCGCCGCGCAGGCGGCCGACTGGGGCCCGACGCGGCATGACGACG
CGCTGCACGACCGCGCGAGCTACCGCTACTACTGGGCGGTGCTGCGCCGCGCGCGCGCGACCGGCCAGCCGCTGCCCGCC
GAGTCGGCGCCGCTCTTCGGCGACGCCGGCGAACGGGCCGCGCGGGGACGCGAAAAATGA

Upstream 100 bases:

>100_bases
GCATGGGCTTTGCCGCAAGCGCCGCCCCGGCGCCCGCGCAGAGCCCGCCCGAATCCGATTTTCACGCTGGCCCAGACCCC
GACCTGACGCAGAAGAACAG

Downstream 100 bases:

>100_bases
ACGGTGCACGGGGGCGGAAAAACTGAATTCGACACGCCAAATAGGTGAAAATAGCGGCCGCTGCGCGCTTCCGGGGCGCG
TGCAGTTCCAACCCCACCCG

Product: putative lyase

Products: NA

Alternate protein names: (3S)-malyl-CoA/beta-methylmalyl-CoA lyase; L-malyl-CoA/beta-methylmalyl-CoA lyase [H]

Number of amino acids: Translated: 339; Mature: 338

Protein sequence:

>339_residues
MSALTPAEVLYEGVAPPAILPCCDHYAGSEKLMLKSLALQAELGPVFDITLDCEDGAAVGREAEHAARVAALVGGEANRF
GRVGVRIHDISHPHWRDDVRVVLRAARPPAYLTLPKVGGAADAAEMCAFIEASRVELGIAQPIPVDVLIETHGALADAAR
IAALPIVATLSFGLMDFVSAHHGAIPDDAMRAPGQFDHPLVRRAKLEIAAACHAHGKTPSHNVTTEVRDMRVVANDARRA
REEFGYTRMWSIHPAQIREIVAAFAPRADDIARASRILLAAQAADWGPTRHDDALHDRASYRYYWAVLRRARATGQPLPA
ESAPLFGDAGERAARGREK

Sequences:

>Translated_339_residues
MSALTPAEVLYEGVAPPAILPCCDHYAGSEKLMLKSLALQAELGPVFDITLDCEDGAAVGREAEHAARVAALVGGEANRF
GRVGVRIHDISHPHWRDDVRVVLRAARPPAYLTLPKVGGAADAAEMCAFIEASRVELGIAQPIPVDVLIETHGALADAAR
IAALPIVATLSFGLMDFVSAHHGAIPDDAMRAPGQFDHPLVRRAKLEIAAACHAHGKTPSHNVTTEVRDMRVVANDARRA
REEFGYTRMWSIHPAQIREIVAAFAPRADDIARASRILLAAQAADWGPTRHDDALHDRASYRYYWAVLRRARATGQPLPA
ESAPLFGDAGERAARGREK
>Mature_338_residues
SALTPAEVLYEGVAPPAILPCCDHYAGSEKLMLKSLALQAELGPVFDITLDCEDGAAVGREAEHAARVAALVGGEANRFG
RVGVRIHDISHPHWRDDVRVVLRAARPPAYLTLPKVGGAADAAEMCAFIEASRVELGIAQPIPVDVLIETHGALADAARI
AALPIVATLSFGLMDFVSAHHGAIPDDAMRAPGQFDHPLVRRAKLEIAAACHAHGKTPSHNVTTEVRDMRVVANDARRAR
EEFGYTRMWSIHPAQIREIVAAFAPRADDIARASRILLAAQAADWGPTRHDDALHDRASYRYYWAVLRRARATGQPLPAE
SAPLFGDAGERAARGREK

Specific function: Catalyzes the reversible condensation of glyoxylate and acetyl-CoA to L-malyl-CoA and the reversible condensation of glyoxylate and propionyl-CoA to beta-methylmalyl-CoA [H]

COG id: COG2301

COG function: function code G; Citrate lyase beta subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HpcH/HpaI aldolase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005000
- InterPro:   IPR011206
- InterPro:   IPR015813 [H]

Pfam domain/function: PF03328 HpcH_HpaI [H]

EC number: =4.1.3.24 [H]

Molecular weight: Translated: 36569; Mature: 36438

Theoretical pI: Translated: 6.92; Mature: 6.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSALTPAEVLYEGVAPPAILPCCDHYAGSEKLMLKSLALQAELGPVFDITLDCEDGAAVG
CCCCCHHHHHHHCCCCCHHHHHHHCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCCCC
REAEHAARVAALVGGEANRFGRVGVRIHDISHPHWRDDVRVVLRAARPPAYLTLPKVGGA
CHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHCCCCCEEECCCCCCC
ADAAEMCAFIEASRVELGIAQPIPVDVLIETHGALADAARIAALPIVATLSFGLMDFVSA
CCHHHHHHHHHHHHHEECCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
HHGAIPDDAMRAPGQFDHPLVRRAKLEIAAACHAHGKTPSHNVTTEVRDMRVVANDARRA
HCCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHH
REEFGYTRMWSIHPAQIREIVAAFAPRADDIARASRILLAAQAADWGPTRHDDALHDRAS
HHHCCCCEEECCCHHHHHHHHHHHCCCHHHHHHHHHHHHEEECCCCCCCCCCHHHHHHHH
YRYYWAVLRRARATGQPLPAESAPLFGDAGERAARGREK
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHCCCCC
>Mature Secondary Structure 
SALTPAEVLYEGVAPPAILPCCDHYAGSEKLMLKSLALQAELGPVFDITLDCEDGAAVG
CCCCHHHHHHHCCCCCHHHHHHHCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCCCC
REAEHAARVAALVGGEANRFGRVGVRIHDISHPHWRDDVRVVLRAARPPAYLTLPKVGGA
CHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHCCCCCEEECCCCCCC
ADAAEMCAFIEASRVELGIAQPIPVDVLIETHGALADAARIAALPIVATLSFGLMDFVSA
CCHHHHHHHHHHHHHEECCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
HHGAIPDDAMRAPGQFDHPLVRRAKLEIAAACHAHGKTPSHNVTTEVRDMRVVANDARRA
HCCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHH
REEFGYTRMWSIHPAQIREIVAAFAPRADDIARASRILLAAQAADWGPTRHDDALHDRAS
HHHCCCCEEECCCHHHHHHHHHHHCCCHHHHHHHHHHHHEEECCCCCCCCCCHHHHHHHH
YRYYWAVLRRARATGQPLPAESAPLFGDAGERAARGREK
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA