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The map label for this gene is glpR [H]

Identifier: 126446730

GI number: 126446730

Start: 1581635

End: 1582393

Strand: Reverse

Name: glpR [H]

Synonym: BMA10247_A1642

Alternate gene names: 126446730

Gene position: 1582393-1581635 (Counterclockwise)

Preceding gene: 126446288

Following gene: 126447549

Centisome position: 67.26

GC content: 71.28

Gene sequence:

>759_bases
ATGCTTGCTGAACAACGTCATCGCTACATCCTGTCCGAACTCGGCCGCGCGGGTGCGCTGTCGGTCGCGCAGCTCGTGAA
CGCGCTCAACGTGTCGCGCGAGACGATCCGCCGCGATCTGAACGCGCTCGCCGCGCGCGGCCTCGTGATCACGACGCATG
GCGGCGCGCTCGCGGCCGACCGCCACGAGCCGAGCGTGTCCGAGCGCGACGCGTCGCACGCGGACGCGAAACGCGTGATC
GGCCGGCGTGCGGCCGAATTCGTGCCCGACGGCGCGTCGGTGCTGCTCGACTCGGGCAGCACGGTTCACGCGGTGGCGCT
CGCGCTCGCCGATCGCCATCGCTTGAGCGTCTACACGAACGACTGGCGGATCGCCGGCGTGCTCGGCCGGCGCAACGGCA
ACCGCGTGACGCTGCTCGGCGGCGAACTCTCCGACGACGAGGACGCGACGTTCGGCCTCGACACGATCCACCAGCTTGCG
CAATACCACGTCGATTTCGCGTTCGTCGGCGCGGGCGGGATCACGCCGGACGGCACGCTGACCGATTACTCGCGCGTCGT
CGCCGAGGTGCGCGGGCGGATGCTCGCGGCGGCGGCCGCGCCGATCGTCGTCGCCGATCATTCGAAGTTCGGCCGCGTGA
CGCCCGTGCGGATCAACGGCTCGGACGCCGCGCGCTTTCTCGTCACCGAGCGCGCGCCGGACAAGGCGATGCGGCGCGCG
CTGACGGCGCGGGGGATCGAACTCGTCGTCTGCGGATGA

Upstream 100 bases:

>100_bases
GCGGGCGATCGGCGGCCGGCGCGAACCGCTCGCGCCGTACTACAATAGCCCGCCATTCGCCCTCCACGCTCCCACCCGCG
GCCCGGCCGCGCCGCGCGCC

Downstream 100 bases:

>100_bases
GCGTGCGTTCGTCGCGTGCATAGCGGACGCGTGCGGCGCGCGCGATGTTTGGCGCGGCCGGCGCGCCGAACCGGTCCGGT
TCGATGCGTGCGGCGCGAAG

Product: DeoR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 252; Mature: 252

Protein sequence:

>252_residues
MLAEQRHRYILSELGRAGALSVAQLVNALNVSRETIRRDLNALAARGLVITTHGGALAADRHEPSVSERDASHADAKRVI
GRRAAEFVPDGASVLLDSGSTVHAVALALADRHRLSVYTNDWRIAGVLGRRNGNRVTLLGGELSDDEDATFGLDTIHQLA
QYHVDFAFVGAGGITPDGTLTDYSRVVAEVRGRMLAAAAAPIVVADHSKFGRVTPVRINGSDAARFLVTERAPDKAMRRA
LTARGIELVVCG

Sequences:

>Translated_252_residues
MLAEQRHRYILSELGRAGALSVAQLVNALNVSRETIRRDLNALAARGLVITTHGGALAADRHEPSVSERDASHADAKRVI
GRRAAEFVPDGASVLLDSGSTVHAVALALADRHRLSVYTNDWRIAGVLGRRNGNRVTLLGGELSDDEDATFGLDTIHQLA
QYHVDFAFVGAGGITPDGTLTDYSRVVAEVRGRMLAAAAAPIVVADHSKFGRVTPVRINGSDAARFLVTERAPDKAMRRA
LTARGIELVVCG
>Mature_252_residues
MLAEQRHRYILSELGRAGALSVAQLVNALNVSRETIRRDLNALAARGLVITTHGGALAADRHEPSVSERDASHADAKRVI
GRRAAEFVPDGASVLLDSGSTVHAVALALADRHRLSVYTNDWRIAGVLGRRNGNRVTLLGGELSDDEDATFGLDTIHQLA
QYHVDFAFVGAGGITPDGTLTDYSRVVAEVRGRMLAAAAAPIVVADHSKFGRVTPVRINGSDAARFLVTERAPDKAMRRA
LTARGIELVVCG

Specific function: Repressor of the glycerol-3-phosphate regulon [H]

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789829, Length=252, Percent_Identity=32.1428571428571, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI87082344, Length=246, Percent_Identity=29.6747967479675, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1789059, Length=254, Percent_Identity=30.7086614173228, Blast_Score=117, Evalue=6e-28,
Organism=Escherichia coli, GI226510968, Length=253, Percent_Identity=30.4347826086957, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1789519, Length=252, Percent_Identity=27.7777777777778, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI1788069, Length=236, Percent_Identity=28.3898305084746, Blast_Score=95, Evalue=3e-21,
Organism=Escherichia coli, GI1789170, Length=229, Percent_Identity=29.6943231441048, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1790635, Length=253, Percent_Identity=25.296442687747, Blast_Score=81, Evalue=8e-17,
Organism=Escherichia coli, GI1787540, Length=209, Percent_Identity=30.1435406698565, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI1787063, Length=247, Percent_Identity=26.7206477732794, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI1790753, Length=214, Percent_Identity=26.1682242990654, Blast_Score=65, Evalue=6e-12,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 26886; Mature: 26886

Theoretical pI: Translated: 9.12; Mature: 9.12

Prosite motif: PS00894 HTH_DEOR_1 ; PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLAEQRHRYILSELGRAGALSVAQLVNALNVSRETIRRDLNALAARGLVITTHGGALAAD
CCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCEEECC
RHEPSVSERDASHADAKRVIGRRAAEFVPDGASVLLDSGSTVHAVALALADRHRLSVYTN
CCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHCCCEEEEEEC
DWRIAGVLGRRNGNRVTLLGGELSDDEDATFGLDTIHQLAQYHVDFAFVGAGGITPDGTL
CEEEEEEEECCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHCCEEEEECCCCCCCCCH
TDYSRVVAEVRGRMLAAAAAPIVVADHSKFGRVTPVRINGSDAARFLVTERAPDKAMRRA
HHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCEEEEEECCCCCEEEEEECCCHHHHHHHH
LTARGIELVVCG
HHHCCEEEEEEC
>Mature Secondary Structure
MLAEQRHRYILSELGRAGALSVAQLVNALNVSRETIRRDLNALAARGLVITTHGGALAAD
CCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCEEECC
RHEPSVSERDASHADAKRVIGRRAAEFVPDGASVLLDSGSTVHAVALALADRHRLSVYTN
CCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHCCCEEEEEEC
DWRIAGVLGRRNGNRVTLLGGELSDDEDATFGLDTIHQLAQYHVDFAFVGAGGITPDGTL
CEEEEEEEECCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHCCEEEEECCCCCCCCCH
TDYSRVVAEVRGRMLAAAAAPIVVADHSKFGRVTPVRINGSDAARFLVTERAPDKAMRRA
HHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCEEEEEECCCCCEEEEEECCCHHHHHHHH
LTARGIELVVCG
HHHCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8955387; 3045764; 9278503 [H]