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The map label for this gene is gcp [H]

Identifier: 126446713

GI number: 126446713

Start: 323777

End: 324856

Strand: Reverse

Name: gcp [H]

Synonym: BMA10247_A0367

Alternate gene names: 126446713

Gene position: 324856-323777 (Counterclockwise)

Preceding gene: 126447958

Following gene: 126447021

Centisome position: 13.81

GC content: 71.3

Gene sequence:

>1080_bases
GTGCGCACGCGCGCGTCGATGCGGCCGCCGCACACCATCATGCTCGTTCTCGGCATCGAAAGCTCCTGCGACGAAACCGG
CCTCGCGCTCTACGACACCGAGCGCGGCCTGCTCGCGCACGCGCTTCACTCGCAGATCGCGATGCACCGCGAATACGGCG
GTGTCGTTCCCGAGCTCGCGTCGCGCGACCACATTCGCCGCGCGCTGCCGCTGCTCGAAGAGGTGCTCGCCGCAAGCGGC
GCGCGCCGCGACGACATCGACGCGATCGCGTTCACGCAGGGGCCCGGCCTCGCGGGCGCGCTGCTCGTCGGCGCGAGCAT
CGCGAACGCGCTCGCGTTCGCGTGGGACAAGCCGACCATCGGCATCCACCACCTCGAAGGGCATCTGCTGTCGCCGCTGC
TCGTCGCCGAGCCGCCGCCGTTTCCGTTCGTCGCGCTGCTCGTGTCGGGCGGCCATACGCAACTGATGCGCGTGAGCGAC
GTCGGCGTCTACGAGACGCTCGGCGAGACGCTCGACGATGCAGCCGGCGAAGCGTTCGACAAGACCGCGAAGCTGCTCGG
CCTCGGCTATCCGGGCGGGCCGGAGGTATCGAGGCTCGCGGAAGCCGGCACCCCGGGCGCGGTCGTGCTGCCGCGGCCGA
TGCTTCATTCGGGGGATCTCGACTTCAGCTTCAGCGGGCTGAAGACCGCCGTGCTCACGCAAATGAAGAAGCTCGAAGCG
GCGCACGCGGGCGGCGCCGTGCTCGAGCGGGCGAAGGCGGATCTCGCGCGCGGCTTCGTCGACGCGGCCGTCGACGTGCT
CGTCGCGAAGTCGCTCGCCGCGTTGAAGGCGACGCGGCTCAAGCGGCTCGTCGTCGCCGGCGGCGTGGGCGCGAACCGGC
AATTGCGCGCGGCGCTGTCGGCCGCCGCCCAAAAGCGCGGCTTCGACGTCCATTATCCCGATCTCGCGCTCTGCACCGAC
AACGGCGCGATGATCGCGCTCGCGGGCGCGCTGCGGCTCGCGCGCTGGCCGTCGCAGGCGAGCCGCGATTACGCGTTCAC
GGTGAAGCCGCGCTGGGATCTCGCGTCGCTCGCGCGATAG

Upstream 100 bases:

>100_bases
GGCGCGGATTGTACCCGCGTCGCGTGCCGCTTCGCCCGCGCGCCGGCTGGCGAAGCGGCCGCGCTGTTATACTTTTCTGT
TACGTTGATTTTCCGGCCGT

Downstream 100 bases:

>100_bases
CGCGCGAAGCACGACGAGCCCGCCATACGGAGCCGGCGCGGCGTGCGGCGGAGCCGAGGCCGCAACGCGCGCGTGCCTGC
TCTCGGGCCCGCCCGATGCC

Product: putative DNA-binding/iron metalloprotein/AP endonuclease

Products: NA

Alternate protein names: Glycoprotease [H]

Number of amino acids: Translated: 359; Mature: 359

Protein sequence:

>359_residues
MRTRASMRPPHTIMLVLGIESSCDETGLALYDTERGLLAHALHSQIAMHREYGGVVPELASRDHIRRALPLLEEVLAASG
ARRDDIDAIAFTQGPGLAGALLVGASIANALAFAWDKPTIGIHHLEGHLLSPLLVAEPPPFPFVALLVSGGHTQLMRVSD
VGVYETLGETLDDAAGEAFDKTAKLLGLGYPGGPEVSRLAEAGTPGAVVLPRPMLHSGDLDFSFSGLKTAVLTQMKKLEA
AHAGGAVLERAKADLARGFVDAAVDVLVAKSLAALKATRLKRLVVAGGVGANRQLRAALSAAAQKRGFDVHYPDLALCTD
NGAMIALAGALRLARWPSQASRDYAFTVKPRWDLASLAR

Sequences:

>Translated_359_residues
MRTRASMRPPHTIMLVLGIESSCDETGLALYDTERGLLAHALHSQIAMHREYGGVVPELASRDHIRRALPLLEEVLAASG
ARRDDIDAIAFTQGPGLAGALLVGASIANALAFAWDKPTIGIHHLEGHLLSPLLVAEPPPFPFVALLVSGGHTQLMRVSD
VGVYETLGETLDDAAGEAFDKTAKLLGLGYPGGPEVSRLAEAGTPGAVVLPRPMLHSGDLDFSFSGLKTAVLTQMKKLEA
AHAGGAVLERAKADLARGFVDAAVDVLVAKSLAALKATRLKRLVVAGGVGANRQLRAALSAAAQKRGFDVHYPDLALCTD
NGAMIALAGALRLARWPSQASRDYAFTVKPRWDLASLAR
>Mature_359_residues
MRTRASMRPPHTIMLVLGIESSCDETGLALYDTERGLLAHALHSQIAMHREYGGVVPELASRDHIRRALPLLEEVLAASG
ARRDDIDAIAFTQGPGLAGALLVGASIANALAFAWDKPTIGIHHLEGHLLSPLLVAEPPPFPFVALLVSGGHTQLMRVSD
VGVYETLGETLDDAAGEAFDKTAKLLGLGYPGGPEVSRLAEAGTPGAVVLPRPMLHSGDLDFSFSGLKTAVLTQMKKLEA
AHAGGAVLERAKADLARGFVDAAVDVLVAKSLAALKATRLKRLVVAGGVGANRQLRAALSAAAQKRGFDVHYPDLALCTD
NGAMIALAGALRLARWPSQASRDYAFTVKPRWDLASLAR

Specific function: Could Be A Metalloprotease. [C]

COG id: COG0533

COG function: function code O; Metal-dependent proteases with possible chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M22 family [H]

Homologues:

Organism=Homo sapiens, GI116812636, Length=336, Percent_Identity=36.3095238095238, Blast_Score=164, Evalue=1e-40,
Organism=Homo sapiens, GI8923380, Length=315, Percent_Identity=30.7936507936508, Blast_Score=129, Evalue=4e-30,
Organism=Escherichia coli, GI1789445, Length=344, Percent_Identity=57.2674418604651, Blast_Score=389, Evalue=1e-109,
Organism=Caenorhabditis elegans, GI17557464, Length=331, Percent_Identity=32.6283987915408, Blast_Score=141, Evalue=5e-34,
Organism=Caenorhabditis elegans, GI71995670, Length=349, Percent_Identity=30.3724928366762, Blast_Score=124, Evalue=7e-29,
Organism=Saccharomyces cerevisiae, GI6320099, Length=343, Percent_Identity=33.5276967930029, Blast_Score=164, Evalue=3e-41,
Organism=Saccharomyces cerevisiae, GI6322891, Length=348, Percent_Identity=27.0114942528736, Blast_Score=111, Evalue=2e-25,
Organism=Drosophila melanogaster, GI20129063, Length=352, Percent_Identity=33.5227272727273, Blast_Score=166, Evalue=2e-41,
Organism=Drosophila melanogaster, GI21357207, Length=328, Percent_Identity=29.2682926829268, Blast_Score=129, Evalue=2e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022450
- InterPro:   IPR000905
- InterPro:   IPR017861 [H]

Pfam domain/function: PF00814 Peptidase_M22 [H]

EC number: =3.4.24.57 [H]

Molecular weight: Translated: 37839; Mature: 37839

Theoretical pI: Translated: 7.83; Mature: 7.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTRASMRPPHTIMLVLGIESSCDETGLALYDTERGLLAHALHSQIAMHREYGGVVPELA
CCCCCCCCCCCEEEEEEECCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCCHHHH
SRDHIRRALPLLEEVLAASGARRDDIDAIAFTQGPGLAGALLVGASIANALAFAWDKPTI
HHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCC
GIHHLEGHLLSPLLVAEPPPFPFVALLVSGGHTQLMRVSDVGVYETLGETLDDAAGEAFD
EEEECCCHHHCCEEECCCCCCCEEEEEECCCCCEEEEECCCCHHHHHHHHHHHHHHHHHH
KTAKLLGLGYPGGPEVSRLAEAGTPGAVVLPRPMLHSGDLDFSFSGLKTAVLTQMKKLEA
HHHHHHCCCCCCCCHHHHHHHCCCCCEEEECCCCCCCCCCCEEHHHHHHHHHHHHHHHHH
AHAGGAVLERAKADLARGFVDAAVDVLVAKSLAALKATRLKRLVVAGGVGANRQLRAALS
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHH
AAAQKRGFDVHYPDLALCTDNGAMIALAGALRLARWPSQASRDYAFTVKPRWDLASLAR
HHHHHCCCCCCCCCEEEEECCCCEEEHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHCC
>Mature Secondary Structure
MRTRASMRPPHTIMLVLGIESSCDETGLALYDTERGLLAHALHSQIAMHREYGGVVPELA
CCCCCCCCCCCEEEEEEECCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCCHHHH
SRDHIRRALPLLEEVLAASGARRDDIDAIAFTQGPGLAGALLVGASIANALAFAWDKPTI
HHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCC
GIHHLEGHLLSPLLVAEPPPFPFVALLVSGGHTQLMRVSDVGVYETLGETLDDAAGEAFD
EEEECCCHHHCCEEECCCCCCCEEEEEECCCCCEEEEECCCCHHHHHHHHHHHHHHHHHH
KTAKLLGLGYPGGPEVSRLAEAGTPGAVVLPRPMLHSGDLDFSFSGLKTAVLTQMKKLEA
HHHHHHCCCCCCCCHHHHHHHCCCCCEEEECCCCCCCCCCCEEHHHHHHHHHHHHHHHHH
AHAGGAVLERAKADLARGFVDAAVDVLVAKSLAALKATRLKRLVVAGGVGANRQLRAALS
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHH
AAAQKRGFDVHYPDLALCTDNGAMIALAGALRLARWPSQASRDYAFTVKPRWDLASLAR
HHHHHCCCCCCCCCEEEEECCCCEEEHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA