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The map label for this gene is mocR [H]

Identifier: 126446532

GI number: 126446532

Start: 428447

End: 429976

Strand: Reverse

Name: mocR [H]

Synonym: BMA10247_A0480

Alternate gene names: 126446532

Gene position: 429976-428447 (Counterclockwise)

Preceding gene: 126446344

Following gene: 126445848

Centisome position: 18.28

GC content: 69.08

Gene sequence:

>1530_bases
TTGGACACCGTGATCCTCTCCGACTGGCTTGCCGCGCGACTCGAGCGGCACTCGGCCGAGCCGATGTACCGGCAACTGCT
GCGGCTGATGCAGCAGGCGATCCTCTCGGGGGAGCTCACGCCCGGCACGAAGCTGCCGAGCTCGCGCACGCTCGCCACCG
ATCTCGCGATCGCGCGCAACACCGTGCTGCACGTGTACGACCAACTGACGACGGAAGGCTACGTGCTGACGACGACGGGC
AGCGGCACCTACGTCGCCGACACGCGCCCCGATGCAGCGGCGATGCGCGCGCAAACCGGCGCGCCCGCGCATCCGTCAGA
CGAAACGCGCGACGCGCAGCAGCGCGCGCACGGCGCGCTGTCGGCGCGCGGCGCGCAACTGATCCGGCATGCGGGCGTGT
CGCGCCGCCAGTGGGGCGCGTTCATGCCGGGCGTGCCCGACGTGTCCGAGTTTCCGACGCGTACATGGAGCCGCCTGCAG
GCGCGGCTGTGGAAGGAAGCGAATCCGGAGCTGCTGACCTATGCGCCGGGCGGCGGCTACCGGCCGTTGCGGCGCGCGCT
GTCCGACTACCTGCGCGTCGCGCGCTCGGTCAAATGCTCGCCCGATCAGATCATCATCACGACGGGCATTCATCAGTCGA
TCGACCTGTCGGTGCGCCTGCTCGCCGACGTCGGCGATCGCGCGTGGGTCGAGGAGCCGTGCTACTGGGGCGTGCGCAGC
GTACTGCAGGCGGCGGGGCTCGCACTCGCGCCCGTGCCCGTCGATCAGGAAGGGCTCGCGCCGCGCGCGCAGGACCTGAA
GCGCCCGCCGCGGCTCGTGCTCGTCACGCCGTCGCATCAATATCCGCTCGGCATGGTGATGAGCCTCGCGCGGCGCCGGA
TGCTGCTCGAATATGCGCGGCAGCATCAATGCTGGATCATCGAAGACGACTACGACAGCGAGTTCCGCTACGGCAGCCGT
CCGCTCGCGTCGCTACAGGGGCTCGACGACGCGGGCCGCGTGATCTACGTCGGCAGTCTCGGCAAGATGCTGTTCCCGAG
CCTGCGCCTCGGCTACATGGTCGTGCCCGAGCACCTCGTCGAGACCTTCCGGACCGGGCTGTCGGAGCTGTATCGCGAAG
GGCAACTGATGCAGCAGGCGGTGCTCGCCGAATTCATCATGGACGGCTATCTGACGTCGCACGTGCGCCGGATGCGCGCG
CTGTACGGCGAGCGCCGCCAGTTGCTGATCGACGCGATCCACGCGCGCTTCGGCGATGCGCTGCCGGTGATGGGCGACGA
GGCGGGCCTGCACCTCGTGATCGGATTGCCGAACGGCTGCGACGACCGGGCGATCACGCAGACCGCGTTCGACGCGGGGG
TGATCGTGCGCCCGCTCACGACGTACTACAACCATGCGGATACCGCGCGCGAGGGATTGCTGCTCGGCTACGCATGCGTG
CCGAACGAGCGCATCGCGCCCGCGTTCGATACGCTCGCGCAGATAATCGAAGCGCATCTGAATCGGCGTGCGAAGCAACG
GGCCGCGTGA

Upstream 100 bases:

>100_bases
CCCCTTTTCGTCTTGGCTCGATATTGCGAGATGCGATTCACTATACGGCGCGCACGGTTCTACAATAGGGAACCATTTCA
ATATTTCCGGTAGAACCACT

Downstream 100 bases:

>100_bases
TGCATGCAATTCGCGCGATGCGCGCGGCGTTCGACACGCCTGCTCGTTACGCCGACGCGCCGCGCACGCACGCCTGCCGC
GCGCATCGGACATGCGCTCC

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 509; Mature: 509

Protein sequence:

>509_residues
MDTVILSDWLAARLERHSAEPMYRQLLRLMQQAILSGELTPGTKLPSSRTLATDLAIARNTVLHVYDQLTTEGYVLTTTG
SGTYVADTRPDAAAMRAQTGAPAHPSDETRDAQQRAHGALSARGAQLIRHAGVSRRQWGAFMPGVPDVSEFPTRTWSRLQ
ARLWKEANPELLTYAPGGGYRPLRRALSDYLRVARSVKCSPDQIIITTGIHQSIDLSVRLLADVGDRAWVEEPCYWGVRS
VLQAAGLALAPVPVDQEGLAPRAQDLKRPPRLVLVTPSHQYPLGMVMSLARRRMLLEYARQHQCWIIEDDYDSEFRYGSR
PLASLQGLDDAGRVIYVGSLGKMLFPSLRLGYMVVPEHLVETFRTGLSELYREGQLMQQAVLAEFIMDGYLTSHVRRMRA
LYGERRQLLIDAIHARFGDALPVMGDEAGLHLVIGLPNGCDDRAITQTAFDAGVIVRPLTTYYNHADTAREGLLLGYACV
PNERIAPAFDTLAQIIEAHLNRRAKQRAA

Sequences:

>Translated_509_residues
MDTVILSDWLAARLERHSAEPMYRQLLRLMQQAILSGELTPGTKLPSSRTLATDLAIARNTVLHVYDQLTTEGYVLTTTG
SGTYVADTRPDAAAMRAQTGAPAHPSDETRDAQQRAHGALSARGAQLIRHAGVSRRQWGAFMPGVPDVSEFPTRTWSRLQ
ARLWKEANPELLTYAPGGGYRPLRRALSDYLRVARSVKCSPDQIIITTGIHQSIDLSVRLLADVGDRAWVEEPCYWGVRS
VLQAAGLALAPVPVDQEGLAPRAQDLKRPPRLVLVTPSHQYPLGMVMSLARRRMLLEYARQHQCWIIEDDYDSEFRYGSR
PLASLQGLDDAGRVIYVGSLGKMLFPSLRLGYMVVPEHLVETFRTGLSELYREGQLMQQAVLAEFIMDGYLTSHVRRMRA
LYGERRQLLIDAIHARFGDALPVMGDEAGLHLVIGLPNGCDDRAITQTAFDAGVIVRPLTTYYNHADTAREGLLLGYACV
PNERIAPAFDTLAQIIEAHLNRRAKQRAA
>Mature_509_residues
MDTVILSDWLAARLERHSAEPMYRQLLRLMQQAILSGELTPGTKLPSSRTLATDLAIARNTVLHVYDQLTTEGYVLTTTG
SGTYVADTRPDAAAMRAQTGAPAHPSDETRDAQQRAHGALSARGAQLIRHAGVSRRQWGAFMPGVPDVSEFPTRTWSRLQ
ARLWKEANPELLTYAPGGGYRPLRRALSDYLRVARSVKCSPDQIIITTGIHQSIDLSVRLLADVGDRAWVEEPCYWGVRS
VLQAAGLALAPVPVDQEGLAPRAQDLKRPPRLVLVTPSHQYPLGMVMSLARRRMLLEYARQHQCWIIEDDYDSEFRYGSR
PLASLQGLDDAGRVIYVGSLGKMLFPSLRLGYMVVPEHLVETFRTGLSELYREGQLMQQAVLAEFIMDGYLTSHVRRMRA
LYGERRQLLIDAIHARFGDALPVMGDEAGLHLVIGLPNGCDDRAITQTAFDAGVIVRPLTTYYNHADTAREGLLLGYACV
PNERIAPAFDTLAQIIEAHLNRRAKQRAA

Specific function: Could play a regulatory role in the transcription of the moc genes for rhizopine catabolism. Could also have an aminotransferase activity [H]

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=393, Percent_Identity=24.6819338422392, Blast_Score=104, Evalue=3e-22,
Organism=Homo sapiens, GI33469970, Length=393, Percent_Identity=24.6819338422392, Blast_Score=104, Evalue=3e-22,
Organism=Escherichia coli, GI1787710, Length=485, Percent_Identity=26.3917525773196, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI1790797, Length=427, Percent_Identity=27.1662763466042, Blast_Score=127, Evalue=1e-30,
Organism=Saccharomyces cerevisiae, GI6321236, Length=318, Percent_Identity=23.2704402515723, Blast_Score=70, Evalue=7e-13,
Organism=Drosophila melanogaster, GI21356535, Length=255, Percent_Identity=24.7058823529412, Blast_Score=73, Evalue=6e-13,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 56567; Mature: 56567

Theoretical pI: Translated: 8.43; Mature: 8.43

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTVILSDWLAARLERHSAEPMYRQLLRLMQQAILSGELTPGTKLPSSRTLATDLAIARN
CCCEEHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHH
TVLHVYDQLTTEGYVLTTTGSGTYVADTRPDAAAMRAQTGAPAHPSDETRDAQQRAHGAL
HHHHHHHHHCCCCEEEEECCCCCEEECCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHH
SARGAQLIRHAGVSRRQWGAFMPGVPDVSEFPTRTWSRLQARLWKEANPELLTYAPGGGY
HHHHHHHHHHCCCCHHHCCCCCCCCCCHHHCCHHHHHHHHHHHHHCCCCCEEEECCCCCC
RPLRRALSDYLRVARSVKCSPDQIIITTGIHQSIDLSVRLLADVGDRAWVEEPCYWGVRS
HHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHEEHHCCCCHHHCCCHHHHHHH
VLQAAGLALAPVPVDQEGLAPRAQDLKRPPRLVLVTPSHQYPLGMVMSLARRRMLLEYAR
HHHHCCCEECCCCCCCCCCCCCHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHH
QHQCWIIEDDYDSEFRYGSRPLASLQGLDDAGRVIYVGSLGKMLFPSLRLGYMVVPEHLV
CCCCEEEECCCCCCCCCCCCCHHHHCCCCCCCCEEEEECCHHHHHHHHHCCCEECHHHHH
ETFRTGLSELYREGQLMQQAVLAEFIMDGYLTSHVRRMRALYGERRQLLIDAIHARFGDA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
LPVMGDEAGLHLVIGLPNGCDDRAITQTAFDAGVIVRPLTTYYNHADTAREGLLLGYACV
CCCCCCCCCEEEEEECCCCCCCCHHHHHHHCCCHHHHHHHHHHCCHHHHHCCEEEEEEEC
PNERIAPAFDTLAQIIEAHLNRRAKQRAA
CCCCCCHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDTVILSDWLAARLERHSAEPMYRQLLRLMQQAILSGELTPGTKLPSSRTLATDLAIARN
CCCEEHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHH
TVLHVYDQLTTEGYVLTTTGSGTYVADTRPDAAAMRAQTGAPAHPSDETRDAQQRAHGAL
HHHHHHHHHCCCCEEEEECCCCCEEECCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHH
SARGAQLIRHAGVSRRQWGAFMPGVPDVSEFPTRTWSRLQARLWKEANPELLTYAPGGGY
HHHHHHHHHHCCCCHHHCCCCCCCCCCHHHCCHHHHHHHHHHHHHCCCCCEEEECCCCCC
RPLRRALSDYLRVARSVKCSPDQIIITTGIHQSIDLSVRLLADVGDRAWVEEPCYWGVRS
HHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHEEHHCCCCHHHCCCHHHHHHH
VLQAAGLALAPVPVDQEGLAPRAQDLKRPPRLVLVTPSHQYPLGMVMSLARRRMLLEYAR
HHHHCCCEECCCCCCCCCCCCCHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHH
QHQCWIIEDDYDSEFRYGSRPLASLQGLDDAGRVIYVGSLGKMLFPSLRLGYMVVPEHLV
CCCCEEEECCCCCCCCCCCCCHHHHCCCCCCCCEEEEECCHHHHHHHHHCCCEECHHHHH
ETFRTGLSELYREGQLMQQAVLAEFIMDGYLTSHVRRMRALYGERRQLLIDAIHARFGDA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
LPVMGDEAGLHLVIGLPNGCDDRAITQTAFDAGVIVRPLTTYYNHADTAREGLLLGYACV
CCCCCCCCCEEEEEECCCCCCCCHHHHHHHCCCHHHHHHHHHHCCHHHHHCCEEEEEEEC
PNERIAPAFDTLAQIIEAHLNRRAKQRAA
CCCCCCHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7845353 [H]