BacMap

Definition	Burkholderia mallei NCTC 10247 chromosome II, complete genome.
Accession	NC_009079
Length	2,352,693

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The map label for this gene is ucpA [H]

Identifier: 126446450

GI number: 126446450

Start: 1722376

End: 1723119

Strand: Reverse

Name: ucpA [H]

Synonym: BMA10247_A1785

Alternate gene names: 126446450

Gene position: 1723119-1722376 (Counterclockwise)

Preceding gene: 126445774

Following gene: 126446810

Centisome position: 73.24

GC content: 70.43

Gene sequence:

>744_bases
ATGGAAGCAAGACTGGCTGGCAAGACGGCGCTCGTCACGGCCGCCGCGCAGGGCATCGGCCGCGCGTCGGCCGAGCGGCT
CGCGCGCGAGGGTGCGCGCGTGATCGCGACGGACATCCGCATCGACGCGCTGCGCGACGGCCCGTTCGATGCGCGCGTGC
TCGACGTGCGCGACGGCGCGGCGATCGACGCGCTCGCCGATGCGATCGGCCCCGTCGACGTGCTGTTCAATTGCGCGGGC
TTCGTGCACGCGGGCTCGGTGCTCGACGCGACCGAAGACGAATGGGACTTCGGCTTCGATCTGAACGTGAAGTCGATGTA
CCGGACGATCCGCGCGTTCCTGCCCGCAATGCTCGCGCGCGAGCGCGGCTCGATCATCAACATGGCGTCGGCCGCCTCGA
GCGTGAAGGGCGTACCGAACCGGTGCGTCTACGGCGCGACGAAGGCGGCCGTGATCGGCTTGACGAAAGCGGTCGCGGCC
GATTTCGTCACGCACGGGATTCGCTGCAATGCGATTTGCCCCGGCACCGTCGAATCGCCGTCGCTCGATGCGCGCATCGC
CGAGCAGGCGCGCGCGCGCGGCGAGCCGATCGACGCGGTGCGCGCCGCGTTCGTCGCGCGCCAGCCGATGGCGCGCATCG
GCAGGCCGCAGGAGATCGCGGCGCTTGTCGCGTATCTCGCGTCCGACGAGGCGTCGTTCACGACGGGGGCGATCCATCTG
ATCGACGGCGGCTGGTCGAACTGA

Upstream 100 bases:

>100_bases
CCGCGGCGAACGGCGAACTGGCGAATGCGAACGGCAAACGTCGCGTCGCCAGGCCGCCGCGTTTCATCCGGCGGACATGA
CTTCATCGGGAGCGGAGGAT

Downstream 100 bases:

>100_bases
CGCGCGCCGCGCGGCGGCCGCGATCCGTTGCCGCGCCGCGCCCGGCACACCTGTTTGAACTCACTGGGCGAATTCATGAA
ACTGCTGCGATACGGGGCGA

Product: short chain dehydrogenase/reductase family oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 247; Mature: 247

Protein sequence:

>247_residues
MEARLAGKTALVTAAAQGIGRASAERLAREGARVIATDIRIDALRDGPFDARVLDVRDGAAIDALADAIGPVDVLFNCAG
FVHAGSVLDATEDEWDFGFDLNVKSMYRTIRAFLPAMLARERGSIINMASAASSVKGVPNRCVYGATKAAVIGLTKAVAA
DFVTHGIRCNAICPGTVESPSLDARIAEQARARGEPIDAVRAAFVARQPMARIGRPQEIAALVAYLASDEASFTTGAIHL
IDGGWSN

Sequences:

>Translated_247_residues
MEARLAGKTALVTAAAQGIGRASAERLAREGARVIATDIRIDALRDGPFDARVLDVRDGAAIDALADAIGPVDVLFNCAG
FVHAGSVLDATEDEWDFGFDLNVKSMYRTIRAFLPAMLARERGSIINMASAASSVKGVPNRCVYGATKAAVIGLTKAVAA
DFVTHGIRCNAICPGTVESPSLDARIAEQARARGEPIDAVRAAFVARQPMARIGRPQEIAALVAYLASDEASFTTGAIHL
IDGGWSN
>Mature_247_residues
MEARLAGKTALVTAAAQGIGRASAERLAREGARVIATDIRIDALRDGPFDARVLDVRDGAAIDALADAIGPVDVLFNCAG
FVHAGSVLDATEDEWDFGFDLNVKSMYRTIRAFLPAMLARERGSIINMASAASSVKGVPNRCVYGATKAAVIGLTKAVAA
DFVTHGIRCNAICPGTVESPSLDARIAEQARARGEPIDAVRAAFVARQPMARIGRPQEIAALVAYLASDEASFTTGAIHL
IDGGWSN

Specific function: Unknown

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI66933014, Length=247, Percent_Identity=57.8947368421053, Blast_Score=260, Evalue=8e-70,
Organism=Homo sapiens, GI15277342, Length=269, Percent_Identity=32.3420074349442, Blast_Score=116, Evalue=2e-26,
Organism=Homo sapiens, GI7705925, Length=251, Percent_Identity=30.2788844621514, Blast_Score=108, Evalue=3e-24,
Organism=Homo sapiens, GI32483357, Length=255, Percent_Identity=30.9803921568627, Blast_Score=102, Evalue=4e-22,
Organism=Homo sapiens, GI126723750, Length=258, Percent_Identity=27.5193798449612, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI19923817, Length=258, Percent_Identity=26.3565891472868, Blast_Score=88, Evalue=8e-18,
Organism=Homo sapiens, GI31542939, Length=215, Percent_Identity=33.0232558139535, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI5031737, Length=246, Percent_Identity=28.8617886178862, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI142976729, Length=199, Percent_Identity=29.6482412060301, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI59889578, Length=146, Percent_Identity=35.6164383561644, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI40254992, Length=251, Percent_Identity=26.2948207171315, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI40807363, Length=195, Percent_Identity=29.7435897435897, Blast_Score=78, Evalue=7e-15,
Organism=Homo sapiens, GI210032110, Length=198, Percent_Identity=24.2424242424242, Blast_Score=75, Evalue=4e-14,
Organism=Homo sapiens, GI4504505, Length=261, Percent_Identity=26.8199233716475, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI4758504, Length=263, Percent_Identity=31.1787072243346, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI33667109, Length=189, Percent_Identity=31.7460317460317, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI10190704, Length=257, Percent_Identity=28.4046692607004, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI126723191, Length=182, Percent_Identity=30.2197802197802, Blast_Score=67, Evalue=1e-11,
Organism=Escherichia coli, GI87082100, Length=253, Percent_Identity=41.1067193675889, Blast_Score=171, Evalue=6e-44,
Organism=Escherichia coli, GI1787335, Length=248, Percent_Identity=35.0806451612903, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1790717, Length=254, Percent_Identity=30.3149606299213, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI1789208, Length=256, Percent_Identity=30.46875, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1786812, Length=248, Percent_Identity=29.8387096774194, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1788459, Length=253, Percent_Identity=30.0395256916996, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI87082160, Length=253, Percent_Identity=28.8537549407115, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI2367365, Length=246, Percent_Identity=30.4878048780488, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1789378, Length=258, Percent_Identity=28.2945736434109, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI1787905, Length=255, Percent_Identity=30.1960784313725, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI2367175, Length=256, Percent_Identity=30.46875, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1787820, Length=184, Percent_Identity=34.7826086956522, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI1786701, Length=237, Percent_Identity=25.3164556962025, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1789057, Length=255, Percent_Identity=25.8823529411765, Blast_Score=68, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI25147288, Length=259, Percent_Identity=31.6602316602317, Blast_Score=124, Evalue=5e-29,
Organism=Caenorhabditis elegans, GI71994604, Length=258, Percent_Identity=32.1705426356589, Blast_Score=113, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17561402, Length=256, Percent_Identity=32.03125, Blast_Score=112, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17555706, Length=256, Percent_Identity=31.25, Blast_Score=111, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI71994600, Length=258, Percent_Identity=30.2325581395349, Blast_Score=106, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17559104, Length=270, Percent_Identity=29.6296296296296, Blast_Score=99, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17508895, Length=196, Percent_Identity=32.1428571428571, Blast_Score=99, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17560676, Length=254, Percent_Identity=29.5275590551181, Blast_Score=99, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17531453, Length=273, Percent_Identity=28.2051282051282, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17538480, Length=270, Percent_Identity=30, Blast_Score=96, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI72000259, Length=264, Percent_Identity=29.1666666666667, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI193204405, Length=271, Percent_Identity=28.0442804428044, Blast_Score=91, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI17562990, Length=264, Percent_Identity=26.8939393939394, Blast_Score=90, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI17562906, Length=269, Percent_Identity=27.8810408921933, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17563726, Length=263, Percent_Identity=27.7566539923954, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17562904, Length=267, Percent_Identity=28.4644194756554, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17562910, Length=267, Percent_Identity=26.9662921348315, Blast_Score=87, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI17560150, Length=264, Percent_Identity=26.1363636363636, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17562908, Length=271, Percent_Identity=28.0442804428044, Blast_Score=86, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17538182, Length=249, Percent_Identity=30.9236947791165, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17565030, Length=277, Percent_Identity=29.2418772563177, Blast_Score=84, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17560332, Length=268, Percent_Identity=28.7313432835821, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17560220, Length=275, Percent_Identity=27.2727272727273, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17536651, Length=261, Percent_Identity=28.3524904214559, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17544670, Length=268, Percent_Identity=25.3731343283582, Blast_Score=81, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17568967, Length=267, Percent_Identity=26.9662921348315, Blast_Score=81, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17551412, Length=277, Percent_Identity=27.0758122743682, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI115534694, Length=251, Percent_Identity=27.8884462151394, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17538486, Length=271, Percent_Identity=27.3062730627306, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17561272, Length=260, Percent_Identity=30.7692307692308, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17536025, Length=259, Percent_Identity=28.5714285714286, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17564282, Length=189, Percent_Identity=26.4550264550265, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI193203117, Length=195, Percent_Identity=25.1282051282051, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI193203115, Length=192, Percent_Identity=25.5208333333333, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17508651, Length=251, Percent_Identity=26.6932270916335, Blast_Score=72, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6323882, Length=198, Percent_Identity=33.3333333333333, Blast_Score=67, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6324126, Length=259, Percent_Identity=25.8687258687259, Blast_Score=65, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6320089, Length=192, Percent_Identity=29.6875, Blast_Score=64, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=256, Percent_Identity=25.390625, Blast_Score=63, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24639444, Length=255, Percent_Identity=33.3333333333333, Blast_Score=129, Evalue=1e-30,
Organism=Drosophila melanogaster, GI23397609, Length=253, Percent_Identity=33.9920948616601, Blast_Score=114, Evalue=7e-26,
Organism=Drosophila melanogaster, GI21355319, Length=257, Percent_Identity=32.295719844358, Blast_Score=108, Evalue=4e-24,
Organism=Drosophila melanogaster, GI21357041, Length=254, Percent_Identity=28.740157480315, Blast_Score=101, Evalue=4e-22,
Organism=Drosophila melanogaster, GI24643142, Length=258, Percent_Identity=31.0077519379845, Blast_Score=99, Evalue=2e-21,
Organism=Drosophila melanogaster, GI28571526, Length=256, Percent_Identity=29.296875, Blast_Score=98, Evalue=7e-21,
Organism=Drosophila melanogaster, GI24644339, Length=255, Percent_Identity=27.4509803921569, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI17737361, Length=260, Percent_Identity=32.6923076923077, Blast_Score=89, Evalue=4e-18,
Organism=Drosophila melanogaster, GI281364892, Length=172, Percent_Identity=35.4651162790698, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI18859837, Length=190, Percent_Identity=32.1052631578947, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24581726, Length=192, Percent_Identity=29.6875, Blast_Score=81, Evalue=6e-16,
Organism=Drosophila melanogaster, GI221510726, Length=256, Percent_Identity=27.34375, Blast_Score=77, Evalue=7e-15,
Organism=Drosophila melanogaster, GI24644337, Length=176, Percent_Identity=32.3863636363636, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24584748, Length=187, Percent_Identity=30.4812834224599, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI161076933, Length=187, Percent_Identity=30.4812834224599, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI21355631, Length=175, Percent_Identity=29.1428571428571, Blast_Score=68, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 25894; Mature: 25894

Theoretical pI: Translated: 6.28; Mature: 6.28

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEARLAGKTALVTAAAQGIGRASAERLAREGARVIATDIRIDALRDGPFDARVLDVRDGA
CCCCCCCCHHHHHHHHHHCCHHHHHHHHHCCCEEEEEEEEEEEECCCCCCCEEEECCCCC
AIDALADAIGPVDVLFNCAGFVHAGSVLDATEDEWDFGFDLNVKSMYRTIRAFLPAMLAR
HHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
ERGSIINMASAASSVKGVPNRCVYGATKAAVIGLTKAVAADFVTHGIRCNAICPGTVESP
HCCCEEEHHHHHHHHCCCCCHHECCCHHHHHHHHHHHHHHHHHHCCEEECEECCCCCCCC
SLDARIAEQARARGEPIDAVRAAFVARQPMARIGRPQEIAALVAYLASDEASFTTGAIHL
CCHHHHHHHHHHCCCCHHHHHHHHHHHCHHHHCCCHHHHHHHHHHHHCCCCCCEECEEEE
IDGGWSN
ECCCCCC
>Mature Secondary Structure
MEARLAGKTALVTAAAQGIGRASAERLAREGARVIATDIRIDALRDGPFDARVLDVRDGA
CCCCCCCCHHHHHHHHHHCCHHHHHHHHHCCCEEEEEEEEEEEECCCCCCCEEEECCCCC
AIDALADAIGPVDVLFNCAGFVHAGSVLDATEDEWDFGFDLNVKSMYRTIRAFLPAMLAR
HHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
ERGSIINMASAASSVKGVPNRCVYGATKAAVIGLTKAVAADFVTHGIRCNAICPGTVESP
HCCCEEEHHHHHHHHCCCCCHHECCCHHHHHHHHHHHHHHHHHHCCEEECEECCCCCCCC
SLDARIAEQARARGEPIDAVRAAFVARQPMARIGRPQEIAALVAYLASDEASFTTGAIHL
CCHHHHHHHHHHCCCCHHHHHHHHHHHCHHHHCCCHHHHHHHHHHHHCCCCCCEECEEEE
IDGGWSN
ECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]