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The map label for this gene is ilvA [H]

Identifier: 126446415

GI number: 126446415

Start: 1286036

End: 1286545

Strand: Reverse

Name: ilvA [H]

Synonym: BMA10247_A1315

Alternate gene names: 126446415

Gene position: 1286545-1286036 (Counterclockwise)

Preceding gene: 126446277

Following gene: 126447437

Centisome position: 54.68

GC content: 70.78

Gene sequence:

>510_bases
ATGCAGTCAGACGACGTCGTCACGGAAACCCCCGAAGCGCCCCCCCGCGAAGCCGTCGCGCCCACGGCGATCGCGCCGCG
CGCGCGCACGCTCGACGATTACCTGAAGCTGGTCCTGAACGCGCGCGTGTACGACGTCGCGCGCGAGACGGCGCTCGAAC
GCGCGCGCAGCCTGTCCGCGCGGCTGGGCAACGCCGTCTACCTGAAGCGCGAGGACAACCAGCCGGTGTTCTCGTTCAAG
CTGCGCGGCGCGTACAACAAGATGGCGCACATCCCGGCCGACGCGCTCGCGCGCGGGGTGATCACCGCGTCGGCGGGCAA
CCATGCGCAGGGCGTCGCGTTCTCGGCCGCGCGGATGAACGTGAAGGCGGTGATCGTCGTGCCGGTGACGACGCCGCAGG
TGAAGGTCGACGCGGTGCGCGCGCACGGCGGGCCGACCGTCGAGGTGATCCAGGCGGGCGAATCGTACAGCGTGACCTGC
CCCCTACAAACAGGGCCAGCCGGAGTCTAG

Upstream 100 bases:

>100_bases
GGTGGGTTAGCGCGCGTCCGAAAGCAGTCACAGCAAACCCGCCCCGTGAGGCGGGTTTTTTGTTTCCGTCTCCCGGGCAT
CCCTCCCAGGAGAGCCTGTC

Downstream 100 bases:

>100_bases
TAAAGTTCGTTTTCGGAGAAGAAGACGAACATGAAGAAGCGCTTTACGGAACAGCAAATCATCGGGTTTCTGAAGGAAGC
CGAGGCCGGTATGCCGGTCA

Product: threonine dehydratase

Products: NA

Alternate protein names: Threonine deaminase [H]

Number of amino acids: Translated: 169; Mature: 169

Protein sequence:

>169_residues
MQSDDVVTETPEAPPREAVAPTAIAPRARTLDDYLKLVLNARVYDVARETALERARSLSARLGNAVYLKREDNQPVFSFK
LRGAYNKMAHIPADALARGVITASAGNHAQGVAFSAARMNVKAVIVVPVTTPQVKVDAVRAHGGPTVEVIQAGESYSVTC
PLQTGPAGV

Sequences:

>Translated_169_residues
MQSDDVVTETPEAPPREAVAPTAIAPRARTLDDYLKLVLNARVYDVARETALERARSLSARLGNAVYLKREDNQPVFSFK
LRGAYNKMAHIPADALARGVITASAGNHAQGVAFSAARMNVKAVIVVPVTTPQVKVDAVRAHGGPTVEVIQAGESYSVTC
PLQTGPAGV
>Mature_169_residues
MQSDDVVTETPEAPPREAVAPTAIAPRARTLDDYLKLVLNARVYDVARETALERARSLSARLGNAVYLKREDNQPVFSFK
LRGAYNKMAHIPADALARGVITASAGNHAQGVAFSAARMNVKAVIVVPVTTPQVKVDAVRAHGGPTVEVIQAGESYSVTC
PLQTGPAGV

Specific function: Catalyzes the formation of alpha-ketobutyrate from threonine in a two-step reaction. The first step is a dehydration of threonine, followed by rehydration and liberation of ammonia [H]

COG id: COG1171

COG function: function code E; Threonine dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the serine/threonine dehydratase family [H]

Homologues:

Organism=Escherichia coli, GI1790207, Length=125, Percent_Identity=56, Blast_Score=133, Evalue=6e-33,
Organism=Escherichia coli, GI1789505, Length=131, Percent_Identity=34.3511450381679, Blast_Score=78, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6320930, Length=115, Percent_Identity=51.304347826087, Blast_Score=115, Evalue=5e-27,
Organism=Saccharomyces cerevisiae, GI6322631, Length=108, Percent_Identity=40.7407407407407, Blast_Score=79, Evalue=3e-16,

Paralogues:

None

Copy number: 1344 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR000634
- InterPro:   IPR005787
- InterPro:   IPR001721 [H]

Pfam domain/function: PF00291 PALP; PF00585 Thr_dehydrat_C [H]

EC number: =4.3.1.19 [H]

Molecular weight: Translated: 17917; Mature: 17917

Theoretical pI: Translated: 9.47; Mature: 9.47

Prosite motif: PS00165 DEHYDRATASE_SER_THR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQSDDVVTETPEAPPREAVAPTAIAPRARTLDDYLKLVLNARVYDVARETALERARSLSA
CCCCCCEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
RLGNAVYLKREDNQPVFSFKLRGAYNKMAHIPADALARGVITASAGNHAQGVAFSAARMN
HCCCEEEEEECCCCCEEEEEECCCCCHHHCCCHHHHHCCEEEECCCCCCCCEEEEEEECC
VKAVIVVPVTTPQVKVDAVRAHGGPTVEVIQAGESYSVTCPLQTGPAGV
EEEEEEEECCCCCEEEEEEECCCCCEEEEEECCCCEEEEEECCCCCCCC
>Mature Secondary Structure
MQSDDVVTETPEAPPREAVAPTAIAPRARTLDDYLKLVLNARVYDVARETALERARSLSA
CCCCCCEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
RLGNAVYLKREDNQPVFSFKLRGAYNKMAHIPADALARGVITASAGNHAQGVAFSAARMN
HCCCEEEEEECCCCCEEEEEECCCCCHHHCCCHHHHHCCEEEECCCCCCCCEEEEEEECC
VKAVIVVPVTTPQVKVDAVRAHGGPTVEVIQAGESYSVTCPLQTGPAGV
EEEEEEEECCCCCEEEEEEECCCCCEEEEEECCCCEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA