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The map label for this gene is folE2 [H]

Identifier: 126446387

GI number: 126446387

Start: 322541

End: 323386

Strand: Direct

Name: folE2 [H]

Synonym: BMA10247_A0366

Alternate gene names: 126446387

Gene position: 322541-323386 (Clockwise)

Preceding gene: 126445825

Following gene: 126446032

Centisome position: 13.71

GC content: 65.96

Gene sequence:

>846_bases
ATGTCGCGCCGCATGACCCTACAAGGATCGAACAAGATGAACCTGATGAATCCCGAATTCGCGATGCCCGACGTGCAGAG
CACCGTCGATACCCGGCAGATGCCGATCCAGCGCGTCGGCGTGCGCGCGGTCCGGCATCCGCTGACGGTGCGCACCGCGG
AAGGCGAGACGCAGGCCACCGTCGGCACCTGGAATCTCGACGTGCATCTGCCCGCCGATCAGAAGGGCACGCACATGTCG
CGCTTCGTCGCGCTGCTCGAGGAGCGCGGCGGGCCGCTGACCGCCGATGCGTTCCGCACGATGCTGGCGACGATGCTCGA
GAAGCTCGAGGCGCGGGCGGGGCGCATCGAGGTGTCGTTTCCGTATTTCGTGAACAAGACGGCGCCCGTGTCGGGCGTGC
GCAGCCTGCTCGATTACGAGGTGACGCTGACGGGCGACGTGCGCGACGGGCTCACACGCGTGTTCGCGAAGGTGCTTGTG
CCGGTGACGAGCCTTTGCCCGTGCTCGAAGAAGATTTCCCAGTACGGCGCGCACAACCAGCGCTCGCACGTGACGATCGA
CGCGGAGCTCGCGGCCGACGTGCCGGTCGAAGATCTGATCCGGATCGCGGAGGAAGAGGCCTCGTGCGAGCTATGGGGCC
TCCTGAAGCGTCCCGACGAGAAGTTCGTCACCGAGCGCGCGTACGAGAATCCGAAGTTCGTCGAGGATCTGGTGCGCGAC
GTCGCGCGGCGGCTCGATGCGGACGAGCGGATCGTCGCCTATGTGCTCGAGGCGGAGAATTTCGAGTCGATCCACAATCA
CAGCGCGTACGCGCTGATCGAGCGAGACAAGCGGCGAGGCGCGTGA

Upstream 100 bases:

>100_bases
GCATCGGGCCGCCGCGCGGCGGGCGCGCGACGGCTTTCCCCCGAAAGCATGGGCCTGCGGGCCCATGTTGCATTTCCGGC
AGGCCATGCGGCATAGGGCG

Downstream 100 bases:

>100_bases
GCGCCGCTGTCGCGCGGCGGCGTTCGCCGTATTCGAGGAAGGGGCCGTTCGAATCGAACGGCCTTTTTCGTTTGGGCGTG
GCGGCGGTGCGTGTGGGTTC

Product: putative GTP cyclohydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 281; Mature: 280

Protein sequence:

>281_residues
MSRRMTLQGSNKMNLMNPEFAMPDVQSTVDTRQMPIQRVGVRAVRHPLTVRTAEGETQATVGTWNLDVHLPADQKGTHMS
RFVALLEERGGPLTADAFRTMLATMLEKLEARAGRIEVSFPYFVNKTAPVSGVRSLLDYEVTLTGDVRDGLTRVFAKVLV
PVTSLCPCSKKISQYGAHNQRSHVTIDAELAADVPVEDLIRIAEEEASCELWGLLKRPDEKFVTERAYENPKFVEDLVRD
VARRLDADERIVAYVLEAENFESIHNHSAYALIERDKRRGA

Sequences:

>Translated_281_residues
MSRRMTLQGSNKMNLMNPEFAMPDVQSTVDTRQMPIQRVGVRAVRHPLTVRTAEGETQATVGTWNLDVHLPADQKGTHMS
RFVALLEERGGPLTADAFRTMLATMLEKLEARAGRIEVSFPYFVNKTAPVSGVRSLLDYEVTLTGDVRDGLTRVFAKVLV
PVTSLCPCSKKISQYGAHNQRSHVTIDAELAADVPVEDLIRIAEEEASCELWGLLKRPDEKFVTERAYENPKFVEDLVRD
VARRLDADERIVAYVLEAENFESIHNHSAYALIERDKRRGA
>Mature_280_residues
SRRMTLQGSNKMNLMNPEFAMPDVQSTVDTRQMPIQRVGVRAVRHPLTVRTAEGETQATVGTWNLDVHLPADQKGTHMSR
FVALLEERGGPLTADAFRTMLATMLEKLEARAGRIEVSFPYFVNKTAPVSGVRSLLDYEVTLTGDVRDGLTRVFAKVLVP
VTSLCPCSKKISQYGAHNQRSHVTIDAELAADVPVEDLIRIAEEEASCELWGLLKRPDEKFVTERAYENPKFVEDLVRDV
ARRLDADERIVAYVLEAENFESIHNHSAYALIERDKRRGA

Specific function: Converts GTP to 7,8-dihydroneopterin triphosphate [H]

COG id: COG1469

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP cyclohydrolase IV family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022838
- InterPro:   IPR003801
- InterPro:   IPR002042 [H]

Pfam domain/function: PF02649 DUF198 [H]

EC number: =3.5.4.16 [H]

Molecular weight: Translated: 31579; Mature: 31448

Theoretical pI: Translated: 6.41; Mature: 6.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRRMTLQGSNKMNLMNPEFAMPDVQSTVDTRQMPIQRVGVRAVRHPLTVRTAEGETQAT
CCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHCCCEEEECCCCCCEE
VGTWNLDVHLPADQKGTHMSRFVALLEERGGPLTADAFRTMLATMLEKLEARAGRIEVSF
EEEEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEEC
PYFVNKTAPVSGVRSLLDYEVTLTGDVRDGLTRVFAKVLVPVTSLCPCSKKISQYGAHNQ
CCEECCCCCHHHHHHHHHEEEEEECCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCC
RSHVTIDAELAADVPVEDLIRIAEEEASCELWGLLKRPDEKFVTERAYENPKFVEDLVRD
CCEEEEEHHHCCCCCHHHHHHHHHHHCCCHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHH
VARRLDADERIVAYVLEAENFESIHNHSAYALIERDKRRGA
HHHHCCCCHHHEEEEECCCCHHHHHCCCCEEEEECHHCCCC
>Mature Secondary Structure 
SRRMTLQGSNKMNLMNPEFAMPDVQSTVDTRQMPIQRVGVRAVRHPLTVRTAEGETQAT
CCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHCCCEEEECCCCCCEE
VGTWNLDVHLPADQKGTHMSRFVALLEERGGPLTADAFRTMLATMLEKLEARAGRIEVSF
EEEEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEEC
PYFVNKTAPVSGVRSLLDYEVTLTGDVRDGLTRVFAKVLVPVTSLCPCSKKISQYGAHNQ
CCEECCCCCHHHHHHHHHEEEEEECCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCC
RSHVTIDAELAADVPVEDLIRIAEEEASCELWGLLKRPDEKFVTERAYENPKFVEDLVRD
CCEEEEEHHHCCCCCHHHHHHHHHHHCCCHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHH
VARRLDADERIVAYVLEAENFESIHNHSAYALIERDKRRGA
HHHHCCCCHHHEEEEECCCCHHHHHCCCCEEEEECHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA