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The map label for this gene is hlY-III [C]

Identifier: 126446384

GI number: 126446384

Start: 1703257

End: 1703877

Strand: Reverse

Name: hlY-III [C]

Synonym: BMA10247_A1768

Alternate gene names: 126446384

Gene position: 1703877-1703257 (Counterclockwise)

Preceding gene: 126445864

Following gene: 126447392

Centisome position: 72.42

GC content: 66.99

Gene sequence:

>621_bases
GTGCATGTCGGTGAGCGTTTCAACAGCATTTCCCATCTCGTCGGCGCGGTGCTGTCGGTGGCGGGGCTCGCCACGCTCGT
GACGATGGGCGCGCTCGACGGCGACGCGTACAAGGTGGTGAGCTTCAGCGTCTACGGCGCGATGCTGTGCGTGCTCTACG
CGATCTCGACGCTCTATCACAGCGTGCGCGGCCCGCGCCTGAAAGCCATCCTGCAGAAATGCGATCACGCGGCCATCTAT
CTGCTGATCGCGGGCAGCTATACGCCGTTTACGCTCGTCACGCTGCGCGGGCCGTGGGGATGGTCGCTGTTCGGCGTGAG
CTGGGGGCTCGCCGCGTTCGGCATCGTGCAGGAGCTCACGCTCGGGCGGCGCACCCGCATCGTATCGATGGCGCTGTACG
TGCTGATGGGCTGGCTCGCGCTCGTCGCGATCCGCCCGCTCGTCCATGCGCTGCCGGCGGCGGGAACGGCGTGGCTCGTC
GCGGGCGGCGTCATCTATAGCGCCGGCATCTACTTTTTCGTCAACGATGAGCGCATCCGCCACGGGCATGGCATCTGGCA
CCTGTTCGTGCTGGCGGGCAGCCTGTGCCAGTTCGTCAGCGTCGCCGGCTACGTCGCGTGA

Upstream 100 bases:

>100_bases
AACGTGGCCGGCGCCTCGATGCGGCCGCCGTCTTCGCCGTGGGACCGGTATCATGTGGACTTCGTGTTGGTGAACCCGTA
TCGGAGTGGAGAGTCGCGTC

Downstream 100 bases:

>100_bases
TGCGCGGCGGCGCGCCCGGCGGCGGCTCGGTCGCGCGCCGGGCGGGATTGCCCGCGCTCAGCTGCCGTGCACGCCGATGA
CGTGCTCATGCACGTTCCAG

Product: hemolysin III

Products: NA

Alternate protein names: Hemolysin III; Hly-III [H]

Number of amino acids: Translated: 206; Mature: 206

Protein sequence:

>206_residues
MHVGERFNSISHLVGAVLSVAGLATLVTMGALDGDAYKVVSFSVYGAMLCVLYAISTLYHSVRGPRLKAILQKCDHAAIY
LLIAGSYTPFTLVTLRGPWGWSLFGVSWGLAAFGIVQELTLGRRTRIVSMALYVLMGWLALVAIRPLVHALPAAGTAWLV
AGGVIYSAGIYFFVNDERIRHGHGIWHLFVLAGSLCQFVSVAGYVA

Sequences:

>Translated_206_residues
MHVGERFNSISHLVGAVLSVAGLATLVTMGALDGDAYKVVSFSVYGAMLCVLYAISTLYHSVRGPRLKAILQKCDHAAIY
LLIAGSYTPFTLVTLRGPWGWSLFGVSWGLAAFGIVQELTLGRRTRIVSMALYVLMGWLALVAIRPLVHALPAAGTAWLV
AGGVIYSAGIYFFVNDERIRHGHGIWHLFVLAGSLCQFVSVAGYVA
>Mature_206_residues
MHVGERFNSISHLVGAVLSVAGLATLVTMGALDGDAYKVVSFSVYGAMLCVLYAISTLYHSVRGPRLKAILQKCDHAAIY
LLIAGSYTPFTLVTLRGPWGWSLFGVSWGLAAFGIVQELTLGRRTRIVSMALYVLMGWLALVAIRPLVHALPAAGTAWLV
AGGVIYSAGIYFFVNDERIRHGHGIWHLFVLAGSLCQFVSVAGYVA

Specific function: Unknown

COG id: COG1272

COG function: function code R; Predicted membrane protein, hemolysin III homolog

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0073 (Hly-III) family [H]

Homologues:

Organism=Homo sapiens, GI154759275, Length=204, Percent_Identity=29.9019607843137, Blast_Score=94, Evalue=6e-20,
Organism=Homo sapiens, GI154759277, Length=228, Percent_Identity=27.1929824561404, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI52630445, Length=203, Percent_Identity=27.0935960591133, Blast_Score=80, Evalue=9e-16,
Organism=Escherichia coli, GI1789266, Length=202, Percent_Identity=44.0594059405941, Blast_Score=157, Evalue=4e-40,
Organism=Caenorhabditis elegans, GI71996356, Length=172, Percent_Identity=34.3023255813954, Blast_Score=87, Evalue=6e-18,
Organism=Drosophila melanogaster, GI24640324, Length=182, Percent_Identity=31.3186813186813, Blast_Score=71, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004254
- InterPro:   IPR005744 [H]

Pfam domain/function: PF03006 HlyIII [H]

EC number: NA

Molecular weight: Translated: 22170; Mature: 22170

Theoretical pI: Translated: 9.55; Mature: 9.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHVGERFNSISHLVGAVLSVAGLATLVTMGALDGDAYKVVSFSVYGAMLCVLYAISTLYH
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
SVRGPRLKAILQKCDHAAIYLLIAGSYTPFTLVTLRGPWGWSLFGVSWGLAAFGIVQELT
HHCCHHHHHHHHHCCCCEEEEEEECCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHH
LGRRTRIVSMALYVLMGWLALVAIRPLVHALPAAGTAWLVAGGVIYSAGIYFFVNDERIR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCEEEEECCCHHH
HGHGIWHLFVLAGSLCQFVSVAGYVA
HCCCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MHVGERFNSISHLVGAVLSVAGLATLVTMGALDGDAYKVVSFSVYGAMLCVLYAISTLYH
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
SVRGPRLKAILQKCDHAAIYLLIAGSYTPFTLVTLRGPWGWSLFGVSWGLAAFGIVQELT
HHCCHHHHHHHHHCCCCEEEEEEECCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHH
LGRRTRIVSMALYVLMGWLALVAIRPLVHALPAAGTAWLVAGGVIYSAGIYFFVNDERIR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCEEEEECCCHHH
HGHGIWHLFVLAGSLCQFVSVAGYVA
HCCCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7495855 [H]