| Definition | Burkholderia mallei NCTC 10247 chromosome II, complete genome. |
|---|---|
| Accession | NC_009079 |
| Length | 2,352,693 |
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The map label for this gene is phbB-1 [H]
Identifier: 126446163
GI number: 126446163
Start: 163483
End: 164229
Strand: Direct
Name: phbB-1 [H]
Synonym: BMA10247_A0193
Alternate gene names: 126446163
Gene position: 163483-164229 (Clockwise)
Preceding gene: 126446697
Following gene: 126446306
Centisome position: 6.95
GC content: 65.46
Gene sequence:
>747_bases ATGCAAGCAAAACGCGTGGCATTCGTGACGGGCGGTATGGGCGGACTGGGTGCGGCGATCAGCCGGCGGCTGCACGACGC CGGCATGGCTGTGGCGGTGTCGCATTCGGAGCGCAACGATCATGTGTCGACGTGGCTGATGCACGAGCGCGACGCCGGAC GCGATTTCAAGGCGTATGCGGTCGACGTCGCGGATTTCGAATCGTGCGAGCGGTGCGCGGAGAAGGTGCTCGCCGATTTC GGCAAGGTCGACGTGCTGATCAACAACGCGGGGATCACGCGCGATGCGACGTTCATGAAGATGACGAAGGGCGACTGGGA CGCGGTGATGCGCACCGATCTCGATGCGATGTTCAACGTGACGAAACAGTTCATCGCGGGCATGGTCGAGCGGCGCTTCG GGCGCATCGTCAACATCGGCTCGGTGAACGGCTCGCGCGGCGCGTTCGGTCAGGCGAATTATGCGTCGGCGAAGGCGGGC ATCCACGGCTTCACGAAGACGCTCGCGCTCGAGACGGCGAAGCGCGGGATCACGGTCAACACGGTGTCGCCCGGCTATCT CGCGACCGCGATGGTCGAAGCGGTGCCGCAGGACGTGCTCGAGGCGAAGATCCTGCCGCAGATTCCGGTTGGCCGGCTCG GCCGGCCCGACGAAGTGGCCGCGCTCATCGCGTTTCTGTGCTCGGACGACGCGGGGTTCGTCACCGGCGCCGATCTCGCG ATCAACGGCGGGATGCACATGTCCTGA
Upstream 100 bases:
>100_bases CAACACATTTTTCAACCCATGCCCGGATGGCCGCCGCGCGACTGTGCTTGCGCAGGGCGCGGCGCCAATGCCGCACCGGG CACCTCATCGGGAGGCCGTG
Downstream 100 bases:
>100_bases CCGGCCGCTACACCGGCGCCGGCCGCACCGAGGCGGCGCACTTTGGCTTCGGCGGGGTGCGATTCGGCTCGATGCGGTGC GCACGGGGCAGCCGGCGTCG
Product: acetoacetyl-CoA reductase
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 248; Mature: 248
Protein sequence:
>248_residues MQAKRVAFVTGGMGGLGAAISRRLHDAGMAVAVSHSERNDHVSTWLMHERDAGRDFKAYAVDVADFESCERCAEKVLADF GKVDVLINNAGITRDATFMKMTKGDWDAVMRTDLDAMFNVTKQFIAGMVERRFGRIVNIGSVNGSRGAFGQANYASAKAG IHGFTKTLALETAKRGITVNTVSPGYLATAMVEAVPQDVLEAKILPQIPVGRLGRPDEVAALIAFLCSDDAGFVTGADLA INGGMHMS
Sequences:
>Translated_248_residues MQAKRVAFVTGGMGGLGAAISRRLHDAGMAVAVSHSERNDHVSTWLMHERDAGRDFKAYAVDVADFESCERCAEKVLADF GKVDVLINNAGITRDATFMKMTKGDWDAVMRTDLDAMFNVTKQFIAGMVERRFGRIVNIGSVNGSRGAFGQANYASAKAG IHGFTKTLALETAKRGITVNTVSPGYLATAMVEAVPQDVLEAKILPQIPVGRLGRPDEVAALIAFLCSDDAGFVTGADLA INGGMHMS >Mature_248_residues MQAKRVAFVTGGMGGLGAAISRRLHDAGMAVAVSHSERNDHVSTWLMHERDAGRDFKAYAVDVADFESCERCAEKVLADF GKVDVLINNAGITRDATFMKMTKGDWDAVMRTDLDAMFNVTKQFIAGMVERRFGRIVNIGSVNGSRGAFGQANYASAKAG IHGFTKTLALETAKRGITVNTVSPGYLATAMVEAVPQDVLEAKILPQIPVGRLGRPDEVAALIAFLCSDDAGFVTGADLA INGGMHMS
Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI15277342, Length=250, Percent_Identity=37.2, Blast_Score=155, Evalue=3e-38, Organism=Homo sapiens, GI40254992, Length=243, Percent_Identity=32.0987654320988, Blast_Score=121, Evalue=5e-28, Organism=Homo sapiens, GI4504505, Length=247, Percent_Identity=33.1983805668016, Blast_Score=119, Evalue=3e-27, Organism=Homo sapiens, GI32483357, Length=244, Percent_Identity=30.327868852459, Blast_Score=115, Evalue=3e-26, Organism=Homo sapiens, GI7705925, Length=244, Percent_Identity=32.3770491803279, Blast_Score=108, Evalue=5e-24, Organism=Homo sapiens, GI19923817, Length=252, Percent_Identity=30.1587301587302, Blast_Score=107, Evalue=7e-24, Organism=Homo sapiens, GI5031737, Length=243, Percent_Identity=28.8065843621399, Blast_Score=99, Evalue=4e-21, Organism=Homo sapiens, GI66933014, Length=172, Percent_Identity=31.3953488372093, Blast_Score=95, Evalue=6e-20, Organism=Homo sapiens, GI10190704, Length=247, Percent_Identity=28.7449392712551, Blast_Score=91, Evalue=9e-19, Organism=Homo sapiens, GI126723750, Length=247, Percent_Identity=26.3157894736842, Blast_Score=89, Evalue=5e-18, Organism=Homo sapiens, GI4758504, Length=257, Percent_Identity=30.3501945525292, Blast_Score=88, Evalue=7e-18, Organism=Homo sapiens, GI59889578, Length=193, Percent_Identity=28.4974093264249, Blast_Score=84, Evalue=1e-16, Organism=Homo sapiens, GI4503301, Length=197, Percent_Identity=28.4263959390863, Blast_Score=83, Evalue=2e-16, Organism=Homo sapiens, GI20149619, Length=201, Percent_Identity=31.3432835820896, Blast_Score=83, Evalue=3e-16, Organism=Homo sapiens, GI157739938, Length=192, Percent_Identity=26.5625, Blast_Score=79, Evalue=5e-15, Organism=Homo sapiens, GI33667109, Length=188, Percent_Identity=29.7872340425532, Blast_Score=77, Evalue=1e-14, Organism=Homo sapiens, GI40807363, Length=198, Percent_Identity=27.2727272727273, Blast_Score=76, Evalue=2e-14, Organism=Homo sapiens, GI7706318, Length=194, Percent_Identity=26.2886597938144, Blast_Score=75, Evalue=7e-14, Organism=Homo sapiens, GI31542939, Length=200, Percent_Identity=27, Blast_Score=72, Evalue=3e-13, Organism=Homo sapiens, GI83715985, Length=257, Percent_Identity=28.4046692607004, Blast_Score=71, Evalue=1e-12, Organism=Homo sapiens, GI7657478, Length=209, Percent_Identity=27.2727272727273, Blast_Score=69, Evalue=4e-12, Organism=Homo sapiens, GI126723191, Length=179, Percent_Identity=28.4916201117318, Blast_Score=66, Evalue=2e-11, Organism=Homo sapiens, GI109715829, Length=240, Percent_Identity=25.4166666666667, Blast_Score=66, Evalue=2e-11, Organism=Homo sapiens, GI22507405, Length=194, Percent_Identity=28.3505154639175, Blast_Score=66, Evalue=3e-11, Organism=Homo sapiens, GI4504503, Length=213, Percent_Identity=28.6384976525822, Blast_Score=65, Evalue=7e-11, Organism=Escherichia coli, GI1787335, Length=245, Percent_Identity=44.4897959183673, Blast_Score=205, Evalue=3e-54, Organism=Escherichia coli, GI87082100, Length=253, Percent_Identity=35.1778656126482, Blast_Score=133, Evalue=1e-32, Organism=Escherichia coli, GI1789208, Length=249, Percent_Identity=32.1285140562249, Blast_Score=127, Evalue=8e-31, Organism=Escherichia coli, GI1788459, Length=255, Percent_Identity=30.1960784313725, Blast_Score=116, Evalue=1e-27, Organism=Escherichia coli, GI1790717, Length=241, Percent_Identity=29.8755186721992, Blast_Score=114, Evalue=7e-27, Organism=Escherichia coli, GI87082160, Length=245, Percent_Identity=28.1632653061224, Blast_Score=109, Evalue=2e-25, Organism=Escherichia coli, GI1786812, Length=226, Percent_Identity=29.2035398230088, Blast_Score=96, Evalue=2e-21, Organism=Escherichia coli, GI2367175, Length=253, Percent_Identity=31.6205533596838, Blast_Score=96, Evalue=2e-21, Organism=Escherichia coli, GI2367365, Length=241, Percent_Identity=32.3651452282158, Blast_Score=94, Evalue=7e-21, Organism=Escherichia coli, GI1789057, Length=257, Percent_Identity=28.7937743190661, Blast_Score=87, Evalue=9e-19, Organism=Escherichia coli, GI1787905, Length=242, Percent_Identity=28.099173553719, Blast_Score=87, Evalue=1e-18, Organism=Escherichia coli, GI1787820, Length=183, Percent_Identity=26.775956284153, Blast_Score=74, Evalue=9e-15, Organism=Escherichia coli, GI1787526, Length=237, Percent_Identity=25.3164556962025, Blast_Score=73, Evalue=2e-14, Organism=Escherichia coli, GI1789378, Length=253, Percent_Identity=25.296442687747, Blast_Score=70, Evalue=1e-13, Organism=Caenorhabditis elegans, GI25147288, Length=245, Percent_Identity=39.1836734693878, Blast_Score=172, Evalue=2e-43, Organism=Caenorhabditis elegans, GI17555706, Length=249, Percent_Identity=37.3493975903614, Blast_Score=157, Evalue=4e-39, Organism=Caenorhabditis elegans, GI17568967, Length=230, Percent_Identity=33.4782608695652, Blast_Score=124, Evalue=4e-29, Organism=Caenorhabditis elegans, GI17560676, Length=244, Percent_Identity=32.3770491803279, Blast_Score=123, Evalue=8e-29, Organism=Caenorhabditis elegans, GI17561402, Length=248, Percent_Identity=29.4354838709677, Blast_Score=105, Evalue=2e-23, Organism=Caenorhabditis elegans, GI17559104, Length=258, Percent_Identity=27.1317829457364, Blast_Score=99, Evalue=2e-21, Organism=Caenorhabditis elegans, GI71994600, Length=255, Percent_Identity=30.5882352941176, Blast_Score=96, Evalue=1e-20, Organism=Caenorhabditis elegans, GI17562910, Length=261, Percent_Identity=28.3524904214559, Blast_Score=95, Evalue=3e-20, Organism=Caenorhabditis elegans, GI71994604, Length=253, Percent_Identity=30.0395256916996, Blast_Score=95, Evalue=3e-20, Organism=Caenorhabditis elegans, GI193203115, Length=194, Percent_Identity=29.8969072164948, Blast_Score=92, Evalue=4e-19, Organism=Caenorhabditis elegans, GI193203117, Length=194, Percent_Identity=29.8969072164948, Blast_Score=92, Evalue=4e-19, Organism=Caenorhabditis elegans, GI17538182, Length=256, Percent_Identity=28.90625, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI17562904, Length=262, Percent_Identity=27.0992366412214, Blast_Score=88, Evalue=3e-18, Organism=Caenorhabditis elegans, GI17560150, Length=254, Percent_Identity=26.7716535433071, Blast_Score=87, Evalue=7e-18, Organism=Caenorhabditis elegans, GI17563726, Length=260, Percent_Identity=26.9230769230769, Blast_Score=86, Evalue=1e-17, Organism=Caenorhabditis elegans, GI17536025, Length=251, Percent_Identity=29.0836653386454, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI17562990, Length=259, Percent_Identity=27.4131274131274, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI17562906, Length=267, Percent_Identity=25.4681647940075, Blast_Score=86, Evalue=3e-17, Organism=Caenorhabditis elegans, GI193204405, Length=259, Percent_Identity=26.2548262548263, Blast_Score=85, Evalue=3e-17, Organism=Caenorhabditis elegans, GI17538486, Length=264, Percent_Identity=26.5151515151515, Blast_Score=84, Evalue=7e-17, Organism=Caenorhabditis elegans, GI17538480, Length=260, Percent_Identity=26.9230769230769, Blast_Score=83, Evalue=1e-16, Organism=Caenorhabditis elegans, GI17560332, Length=261, Percent_Identity=27.9693486590038, Blast_Score=82, Evalue=2e-16, Organism=Caenorhabditis elegans, GI17562908, Length=263, Percent_Identity=25.8555133079848, Blast_Score=82, Evalue=2e-16, Organism=Caenorhabditis elegans, GI17508895, Length=195, Percent_Identity=27.6923076923077, Blast_Score=81, Evalue=4e-16, Organism=Caenorhabditis elegans, GI17536651, Length=249, Percent_Identity=28.1124497991968, Blast_Score=81, Evalue=4e-16, Organism=Caenorhabditis elegans, GI17508651, Length=247, Percent_Identity=29.1497975708502, Blast_Score=81, Evalue=6e-16, Organism=Caenorhabditis elegans, GI17551412, Length=262, Percent_Identity=24.4274809160305, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI115534694, Length=243, Percent_Identity=28.8065843621399, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI72000259, Length=257, Percent_Identity=24.9027237354086, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI17565030, Length=264, Percent_Identity=26.5151515151515, Blast_Score=77, Evalue=1e-14, Organism=Caenorhabditis elegans, GI17561272, Length=197, Percent_Identity=27.4111675126904, Blast_Score=74, Evalue=8e-14, Organism=Caenorhabditis elegans, GI17564282, Length=198, Percent_Identity=24.7474747474747, Blast_Score=74, Evalue=9e-14, Organism=Caenorhabditis elegans, GI17531453, Length=256, Percent_Identity=23.4375, Blast_Score=73, Evalue=1e-13, Organism=Caenorhabditis elegans, GI17544670, Length=266, Percent_Identity=23.3082706766917, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI17560220, Length=256, Percent_Identity=23.828125, Blast_Score=67, Evalue=1e-11, Organism=Saccharomyces cerevisiae, GI6322861, Length=233, Percent_Identity=34.3347639484979, Blast_Score=117, Evalue=1e-27, Organism=Saccharomyces cerevisiae, GI6324126, Length=247, Percent_Identity=29.1497975708502, Blast_Score=91, Evalue=2e-19, Organism=Drosophila melanogaster, GI24639444, Length=248, Percent_Identity=37.0967741935484, Blast_Score=155, Evalue=2e-38, Organism=Drosophila melanogaster, GI24644339, Length=253, Percent_Identity=33.9920948616601, Blast_Score=121, Evalue=4e-28, Organism=Drosophila melanogaster, GI23397609, Length=251, Percent_Identity=34.2629482071713, Blast_Score=119, Evalue=2e-27, Organism=Drosophila melanogaster, GI21357041, Length=249, Percent_Identity=32.5301204819277, Blast_Score=115, Evalue=3e-26, Organism=Drosophila melanogaster, GI21355319, Length=246, Percent_Identity=29.2682926829268, Blast_Score=114, Evalue=9e-26, Organism=Drosophila melanogaster, GI18859837, Length=236, Percent_Identity=31.3559322033898, Blast_Score=105, Evalue=2e-23, Organism=Drosophila melanogaster, GI28571526, Length=248, Percent_Identity=32.6612903225806, Blast_Score=105, Evalue=3e-23, Organism=Drosophila melanogaster, GI24643142, Length=250, Percent_Identity=28.8, Blast_Score=98, Evalue=5e-21, Organism=Drosophila melanogaster, GI24644337, Length=172, Percent_Identity=36.046511627907, Blast_Score=88, Evalue=6e-18, Organism=Drosophila melanogaster, GI17737361, Length=259, Percent_Identity=28.957528957529, Blast_Score=85, Evalue=6e-17, Organism=Drosophila melanogaster, GI21358495, Length=191, Percent_Identity=30.8900523560209, Blast_Score=82, Evalue=4e-16, Organism=Drosophila melanogaster, GI21355631, Length=167, Percent_Identity=29.3413173652695, Blast_Score=77, Evalue=1e-14, Organism=Drosophila melanogaster, GI24581726, Length=142, Percent_Identity=30.9859154929577, Blast_Score=77, Evalue=1e-14, Organism=Drosophila melanogaster, GI24641232, Length=210, Percent_Identity=30.952380952381, Blast_Score=73, Evalue=2e-13, Organism=Drosophila melanogaster, GI24649181, Length=190, Percent_Identity=30.5263157894737, Blast_Score=72, Evalue=4e-13, Organism=Drosophila melanogaster, GI116007236, Length=235, Percent_Identity=29.3617021276596, Blast_Score=72, Evalue=5e-13, Organism=Drosophila melanogaster, GI24665243, Length=192, Percent_Identity=32.2916666666667, Blast_Score=71, Evalue=7e-13, Organism=Drosophila melanogaster, GI221331218, Length=201, Percent_Identity=30.8457711442786, Blast_Score=70, Evalue=1e-12, Organism=Drosophila melanogaster, GI24665247, Length=191, Percent_Identity=30.3664921465969, Blast_Score=67, Evalue=1e-11, Organism=Drosophila melanogaster, GI221331216, Length=200, Percent_Identity=29, Blast_Score=66, Evalue=2e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR011283 - InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.36 [H]
Molecular weight: Translated: 26458; Mature: 26458
Theoretical pI: Translated: 7.13; Mature: 7.13
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.2 %Cys (Translated Protein) 4.8 %Met (Translated Protein) 6.0 %Cys+Met (Translated Protein) 1.2 %Cys (Mature Protein) 4.8 %Met (Mature Protein) 6.0 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MQAKRVAFVTGGMGGLGAAISRRLHDAGMAVAVSHSERNDHVSTWLMHERDAGRDFKAYA CCCCEEEEEECCCCHHHHHHHHHHHHCCEEEEEECCCCCCHHHHHHEECCCCCCCCEEEE VDVADFESCERCAEKVLADFGKVDVLINNAGITRDATFMKMTKGDWDAVMRTDLDAMFNV EEHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCEEEECCCCHHHHHHHHHHHHHHH TKQFIAGMVERRFGRIVNIGSVNGSRGAFGQANYASAKAGIHGFTKTLALETAKRGITVN HHHHHHHHHHHHHCCEEEECCCCCCCCCCCCCCCHHHHHCHHHHHHHHHHHHHHCCEEEE TVSPGYLATAMVEAVPQDVLEAKILPQIPVGRLGRPDEVAALIAFLCSDDAGFVTGADLA ECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEECCCEE INGGMHMS ECCCCCCC >Mature Secondary Structure MQAKRVAFVTGGMGGLGAAISRRLHDAGMAVAVSHSERNDHVSTWLMHERDAGRDFKAYA CCCCEEEEEECCCCHHHHHHHHHHHHCCEEEEEECCCCCCHHHHHHEECCCCCCCCEEEE VDVADFESCERCAEKVLADFGKVDVLINNAGITRDATFMKMTKGDWDAVMRTDLDAMFNV EEHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCEEEECCCCHHHHHHHHHHHHHHH TKQFIAGMVERRFGRIVNIGSVNGSRGAFGQANYASAKAGIHGFTKTLALETAKRGITVN HHHHHHHHHHHHHCCEEEECCCCCCCCCCCCCCCHHHHHCHHHHHHHHHHHHHHCCEEEE TVSPGYLATAMVEAVPQDVLEAKILPQIPVGRLGRPDEVAALIAFLCSDDAGFVTGADLA ECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEECCCEE INGGMHMS ECCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 2670935 [H]