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The map label for this gene is nemR [H]

Identifier: 126445861

GI number: 126445861

Start: 1446230

End: 1446832

Strand: Reverse

Name: nemR [H]

Synonym: BMA10247_A1493

Alternate gene names: 126445861

Gene position: 1446832-1446230 (Counterclockwise)

Preceding gene: 126446372

Following gene: 126447446

Centisome position: 61.5

GC content: 67.66

Gene sequence:

>603_bases
ATGAACGCCGCAACCACCGCCGACGTCCGGCAGCACATTCTCGACACCGCCAAGCCCATCATGCTCTGCAAGGGCTTCAC
GGGCGTCGGCCTGAACGAGATCCTGGCGGCGGCCGGCGTCCCGAAGGGGTCGTTCTACCATTATTTCGGGTCGAAAGAGG
CGTTCGGCGAATCGATTCTCGAATCGTATTTCGACGATTACGTCGCGCATCTCGACGAACTGCTCGTGCGCGGCCCCGGC
GCCGCGATCGATCGGCTGATGCGCTACTGGACCCAGTGGCAGCAGATGCAGATGGGCAACGACCCCGAAGGCAAGTGCCT
CGTCGTCAAGCTCGGCGCCGAGGTGTGCGATCTGTCGGAGGCGATGCGCGCGGCGCTCGAGCGCGGCACGTCGCAGATCG
TCGCGCGGCTCGCCGCGTGCATCGCGGCGGCGCTCGACGACGGCTCGCTGAAGGTCGATCTCGAGCCGCAGCAGACGGCC
GCGATGCTGTACGAGCTGTGGGTCGGCGCGACGCTCATCGAGAAGATCCGGCGCGACGGCGAGCCGCTCGCCGTCGCGAT
GGCGAGCACGCGCCGGGTCCTCGGTCTGACGGGCGCGCGTTGA

Upstream 100 bases:

>100_bases
CGCCGTTTTCACCGTGTCTGCCGGCGCATTCCCTATCGCGCCCCAGGCCCATTTTCCGTTGCTAGACGACTGGTCTAATC
CCGCGCTATCATCCACCCTC

Downstream 100 bases:

>100_bases
ACAGACAGGGAATGCGCGACGGCGCGTACGATGGAAAGCGCGCCGCCGCGTTTTTTCACGATCATTTTCTAGACGACCGG
TCTATTAGCGGGCATGCAAC

Product: TetR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 200; Mature: 200

Protein sequence:

>200_residues
MNAATTADVRQHILDTAKPIMLCKGFTGVGLNEILAAAGVPKGSFYHYFGSKEAFGESILESYFDDYVAHLDELLVRGPG
AAIDRLMRYWTQWQQMQMGNDPEGKCLVVKLGAEVCDLSEAMRAALERGTSQIVARLAACIAAALDDGSLKVDLEPQQTA
AMLYELWVGATLIEKIRRDGEPLAVAMASTRRVLGLTGAR

Sequences:

>Translated_200_residues
MNAATTADVRQHILDTAKPIMLCKGFTGVGLNEILAAAGVPKGSFYHYFGSKEAFGESILESYFDDYVAHLDELLVRGPG
AAIDRLMRYWTQWQQMQMGNDPEGKCLVVKLGAEVCDLSEAMRAALERGTSQIVARLAACIAAALDDGSLKVDLEPQQTA
AMLYELWVGATLIEKIRRDGEPLAVAMASTRRVLGLTGAR
>Mature_200_residues
MNAATTADVRQHILDTAKPIMLCKGFTGVGLNEILAAAGVPKGSFYHYFGSKEAFGESILESYFDDYVAHLDELLVRGPG
AAIDRLMRYWTQWQQMQMGNDPEGKCLVVKLGAEVCDLSEAMRAALERGTSQIVARLAACIAAALDDGSLKVDLEPQQTA
AMLYELWVGATLIEKIRRDGEPLAVAMASTRRVLGLTGAR

Specific function: Represses the transcription of the nemRA operon by binding to the nemR box [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH tetR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI145693141, Length=194, Percent_Identity=44.3298969072165, Blast_Score=167, Evalue=5e-43,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR015893
- InterPro:   IPR011075
- InterPro:   IPR001647 [H]

Pfam domain/function: PF00440 TetR_N [H]

EC number: NA

Molecular weight: Translated: 21709; Mature: 21709

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: PS50977 HTH_TETR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAATTADVRQHILDTAKPIMLCKGFTGVGLNEILAAAGVPKGSFYHYFGSKEAFGESIL
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCEEEECCCHHHHHHHHH
ESYFDDYVAHLDELLVRGPGAAIDRLMRYWTQWQQMQMGNDPEGKCLVVKLGAEVCDLSE
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHH
AMRAALERGTSQIVARLAACIAAALDDGSLKVDLEPQQTAAMLYELWVGATLIEKIRRDG
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHCC
EPLAVAMASTRRVLGLTGAR
CCEEEHHHHHHHHHHCCCCC
>Mature Secondary Structure
MNAATTADVRQHILDTAKPIMLCKGFTGVGLNEILAAAGVPKGSFYHYFGSKEAFGESIL
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCEEEECCCHHHHHHHHH
ESYFDDYVAHLDELLVRGPGAAIDRLMRYWTQWQQMQMGNDPEGKCLVVKLGAEVCDLSE
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHH
AMRAALERGTSQIVARLAACIAAALDDGSLKVDLEPQQTAAMLYELWVGATLIEKIRRDG
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHCC
EPLAVAMASTRRVLGLTGAR
CCEEEHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]