Click here to switch to the map view.

The map label for this gene is adc

Identifier: 126445814

GI number: 126445814

Start: 18140

End: 18880

Strand: Reverse

Name: adc

Synonym: BMA10247_A0022

Alternate gene names: 126445814

Gene position: 18880-18140 (Counterclockwise)

Preceding gene: 126447929

Following gene: 126447595

Centisome position: 0.8

GC content: 64.1

Gene sequence:

>741_bases
ATGAAGCCCAGCCAAGTCCGATCGAAAGCATTCGCGATGCCGCTCACGAGCCCGGCATTCCCGATGGGCCCTTACCGTTT
CGTCAATCGGGAATTCCTGATCATCACGTATCGCACCGACATGGATCGCCTGCGCGAAATCGTGCCGGAGCCGCTCGAGG
TCAAGGAACCACTCGTTCATTACGAATTCATTCGCATGCCCGATTCGACCGGCTTCGGCGATTACACCGAGAGCGGCCAG
GTGATCCCCGTCGAATACAAGGGCCAGCCCGGCGGCTATACGCTCGCGATGTATCTGAACGATCACCCGCCGATCGCGGG
CGGCCGCGAATTGTGGGGATTCCCGAAGAAACTCGCGCAGCCGACGCTGCAGACGCACATCGATACGCTGCTCGGCACGC
TCGACTACGGCCCCGTGCGCGTCGCGACGGGCACGATGGGCTACAAGCACCAGGAGCTCGATCTCGAAGAGCAGGCAAAG
CGCCTCGCCGGCGCGAACTTCCTGCTGAAGATCATCCCGCACGTCGACGGCTCGGCGCGCGTGTGCGAGCTCGTGCGCTA
TTACCTGCAGGACATCGAGATGAAGGGCGCGTGGACGGGCCCCGCGTCGCTGCAGCTCGCGCCGCATGCGCTCGCGCCCG
TCGCCGATCTGCCGGTGCTCGAGATCGTGGAGGCGCGGCACCTGCTCGCCGATTTGACGCTCGGCCTCGGCGAAGTCGTC
TACGATTACCTCGCGCAGTGA

Upstream 100 bases:

>100_bases
ATTCCGCAATAATCTTTTCCAGTTGCGGCATCGCACAATCGATTCTCGGAAGCATACGATATCGGCACCCCGACAACGAA
GCGATCCACAAGGAGTCCGC

Downstream 100 bases:

>100_bases
CGCAAGCCCCTTCGTTCCCTTTCACTTTCTCGACAGGAATTCGATCATGAGCAATCTGAATGGCAAAACCGCCATCGTGA
CGGGCGCGGCGAGCGGCATC

Product: acetoacetate decarboxylase

Products: NA

Alternate protein names: AAD; ADC

Number of amino acids: Translated: 246; Mature: 246

Protein sequence:

>246_residues
MKPSQVRSKAFAMPLTSPAFPMGPYRFVNREFLIITYRTDMDRLREIVPEPLEVKEPLVHYEFIRMPDSTGFGDYTESGQ
VIPVEYKGQPGGYTLAMYLNDHPPIAGGRELWGFPKKLAQPTLQTHIDTLLGTLDYGPVRVATGTMGYKHQELDLEEQAK
RLAGANFLLKIIPHVDGSARVCELVRYYLQDIEMKGAWTGPASLQLAPHALAPVADLPVLEIVEARHLLADLTLGLGEVV
YDYLAQ

Sequences:

>Translated_246_residues
MKPSQVRSKAFAMPLTSPAFPMGPYRFVNREFLIITYRTDMDRLREIVPEPLEVKEPLVHYEFIRMPDSTGFGDYTESGQ
VIPVEYKGQPGGYTLAMYLNDHPPIAGGRELWGFPKKLAQPTLQTHIDTLLGTLDYGPVRVATGTMGYKHQELDLEEQAK
RLAGANFLLKIIPHVDGSARVCELVRYYLQDIEMKGAWTGPASLQLAPHALAPVADLPVLEIVEARHLLADLTLGLGEVV
YDYLAQ
>Mature_246_residues
MKPSQVRSKAFAMPLTSPAFPMGPYRFVNREFLIITYRTDMDRLREIVPEPLEVKEPLVHYEFIRMPDSTGFGDYTESGQ
VIPVEYKGQPGGYTLAMYLNDHPPIAGGRELWGFPKKLAQPTLQTHIDTLLGTLDYGPVRVATGTMGYKHQELDLEEQAK
RLAGANFLLKIIPHVDGSARVCELVRYYLQDIEMKGAWTGPASLQLAPHALAPVADLPVLEIVEARHLLADLTLGLGEVV
YDYLAQ

Specific function: Catalyzes the conversion of acetoacetate to acetone and carbon dioxide

COG id: COG4689

COG function: function code Q; Acetoacetate decarboxylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ADC family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ADC_BURM7 (A3MAE3)

Other databases:

- EMBL:   CP000547
- RefSeq:   YP_001077229.1
- ProteinModelPortal:   A3MAE3
- SMR:   A3MAE3
- GeneID:   4891372
- GenomeReviews:   CP000547_GR
- KEGG:   bmn:BMA10247_A0022
- TIGR:   BMA10247_A0022
- HOGENOM:   HBG294597
- OMA:   MGYKHRP
- ProtClustDB:   PRK02265
- BioCyc:   BMAL320389:BMA10247_A0022-MONOMER
- HAMAP:   MF_00597
- InterPro:   IPR010451

Pfam domain/function: PF06314 ADC

EC number: =4.1.1.4

Molecular weight: Translated: 27494; Mature: 27494

Theoretical pI: Translated: 5.60; Mature: 5.60

Prosite motif: NA

Important sites: ACT_SITE 116-116

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPSQVRSKAFAMPLTSPAFPMGPYRFVNREFLIITYRTDMDRLREIVPEPLEVKEPLVH
CCCHHHHHHHHCCCCCCCCCCCCCHHCCCCEEEEEEEECCHHHHHHHCCCCCHHHCCHHH
YEFIRMPDSTGFGDYTESGQVIPVEYKGQPGGYTLAMYLNDHPPIAGGRELWGFPKKLAQ
HHEEECCCCCCCCCCCCCCCEEEEEECCCCCCEEEEEEECCCCCCCCCHHHCCCCHHHHC
PTLQTHIDTLLGTLDYGPVRVATGTMGYKHQELDLEEQAKRLAGANFLLKIIPHVDGSAR
HHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCHHHHHHHHHCCCEEEHEECCCCCHHH
VCELVRYYLQDIEMKGAWTGPASLQLAPHALAPVADLPVLEIVEARHLLADLTLGLGEVV
HHHHHHHHHHHHHCCCCCCCCCCEEECCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
YDYLAQ
HHHHCC
>Mature Secondary Structure
MKPSQVRSKAFAMPLTSPAFPMGPYRFVNREFLIITYRTDMDRLREIVPEPLEVKEPLVH
CCCHHHHHHHHCCCCCCCCCCCCCHHCCCCEEEEEEEECCHHHHHHHCCCCCHHHCCHHH
YEFIRMPDSTGFGDYTESGQVIPVEYKGQPGGYTLAMYLNDHPPIAGGRELWGFPKKLAQ
HHEEECCCCCCCCCCCCCCCEEEEEECCCCCCEEEEEEECCCCCCCCCHHHCCCCHHHHC
PTLQTHIDTLLGTLDYGPVRVATGTMGYKHQELDLEEQAKRLAGANFLLKIIPHVDGSAR
HHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCHHHHHHHHHCCCEEEHEECCCCCHHH
VCELVRYYLQDIEMKGAWTGPASLQLAPHALAPVADLPVLEIVEARHLLADLTLGLGEVV
HHHHHHHHHHHHHCCCCCCCCCCEEECCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
YDYLAQ
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA