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The map label for this gene is apbE [H]

Identifier: 126445696

GI number: 126445696

Start: 1569662

End: 1570876

Strand: Direct

Name: apbE [H]

Synonym: BMA10247_A1630

Alternate gene names: 126445696

Gene position: 1569662-1570876 (Clockwise)

Preceding gene: 126446958

Following gene: 126447955

Centisome position: 66.72

GC content: 73.33

Gene sequence:

>1215_bases
ATGTCGAAGACGTCTATTGAATGGTCGCCCGGCGCGCGGCTGAATCGCTGCCGCGCAAGCGGCGCGACGATGGGCACGCG
CTACGGCGCGCAGTTCTACGCGCCGCCGACGGCCGACGCGAGGGCGATCGCGGCCGCCCTCGACGCGGCGGTGCGGGCGG
TCGACGCGCAGATGTCGAACTGGAAGGCCGATTCGGATCTGTCGCGGCTCAATCGCGCGACGCCCGGAAGCTGGACGCCG
ATCTGCGCGAACCTCGCCGCGGTGCTCGTGCGCGCGCGGGAAATCGGCCGCGAGACGGACAACGCGTTCAACATCGGCGT
CGGCACGCTCGTCGATCGATGGGGATTCGGGCCGGGCGCGGCCGCGAACCGACAAGCGGACAACGAACGGGCGGCGAATC
GACAGGCGGCCGGCCGACACACGGTTGCTCGACGTACGGTTGCTCGACACATGGTTGCTCGACACACGGTTGATCGACAC
ACGGCGGACCGGCAAACGGCGGACCGACAAACGAAGGACGGGCGCACGCCGGACCGCCAGCCGGCGCGCCCGGCCGGCCC
CGCGAACGGGTTGTCGGGCGCGATCGACGCGCGCCGCCGCGCGTCGATCCTGCGCGGCCCCGTGCCGTCGCCGTGCCGCC
CGATCGACGAACTGCTCGAAGTCGATGTCGCACGGGGCCGGGTGCGCCGGCTCGCGGACGTCGCCTTCGACCTGTGCGGG
ATCGCGAAGGGCTTCGGCGTGGACGAGCTTGCGCGCGTGCTCGATCGCCACGGCATCGGCGCATGGCTCGTCGGCATCGA
CGGCGAGCTGCGCGCGCGCGGATGCAAGCCGGACGGCTCGCCGTGGGCGATCGCGCTCGAAGCGCCCGACTACGGCCGGC
GCGGCGCGATGGGCGCGATCGATCTCGTCGACGCGGCCGTCGCGACCTCCGGCGATTACCGGCATTGGGCCGACTTCGGC
GGCGAACGCCTCTCGCATACGATGGACCCGCGCGCCGGCGCGCCGCTGCGCGGCGACATCGCCTCGGTCACGGTCGTCGC
GCCGACCTGCACCGACGCGGACGCGTACGCCACCGCGTTGATGGTGCTCGGCGCGCAGGCGGGATGCGCGCACGCCGAAC
GCCACGGGCTCGACGCGCTGTTCGTCGTGCGCGACGGCGACGCGCTGCGCACGATCGGCTGCGGCGCTTTCGCGGACGCG
GGGCCGGCGGGCTGA

Upstream 100 bases:

>100_bases
TGCGGCGGCCGCGCGATGGCCGACGGCGTCGCGCGCGCGTGGGAGCGCATCCTGGCGGATTCCGGCTCGTCCGTCGCGCA
ATTGAAGCAGCAGGGGCGCT

Downstream 100 bases:

>100_bases
GCGCCGCGCGGCGCTTACACGTCGAACTTCACGCCCTGCGCGAGCGGCAATTCGCGGCTGTAGTTGATCGTGTTCGTCGC
GCGGCGCATGTAGCTCTTCC

Product: ApbE family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 404; Mature: 403

Protein sequence:

>404_residues
MSKTSIEWSPGARLNRCRASGATMGTRYGAQFYAPPTADARAIAAALDAAVRAVDAQMSNWKADSDLSRLNRATPGSWTP
ICANLAAVLVRAREIGRETDNAFNIGVGTLVDRWGFGPGAAANRQADNERAANRQAAGRHTVARRTVARHMVARHTVDRH
TADRQTADRQTKDGRTPDRQPARPAGPANGLSGAIDARRRASILRGPVPSPCRPIDELLEVDVARGRVRRLADVAFDLCG
IAKGFGVDELARVLDRHGIGAWLVGIDGELRARGCKPDGSPWAIALEAPDYGRRGAMGAIDLVDAAVATSGDYRHWADFG
GERLSHTMDPRAGAPLRGDIASVTVVAPTCTDADAYATALMVLGAQAGCAHAERHGLDALFVVRDGDALRTIGCGAFADA
GPAG

Sequences:

>Translated_404_residues
MSKTSIEWSPGARLNRCRASGATMGTRYGAQFYAPPTADARAIAAALDAAVRAVDAQMSNWKADSDLSRLNRATPGSWTP
ICANLAAVLVRAREIGRETDNAFNIGVGTLVDRWGFGPGAAANRQADNERAANRQAAGRHTVARRTVARHMVARHTVDRH
TADRQTADRQTKDGRTPDRQPARPAGPANGLSGAIDARRRASILRGPVPSPCRPIDELLEVDVARGRVRRLADVAFDLCG
IAKGFGVDELARVLDRHGIGAWLVGIDGELRARGCKPDGSPWAIALEAPDYGRRGAMGAIDLVDAAVATSGDYRHWADFG
GERLSHTMDPRAGAPLRGDIASVTVVAPTCTDADAYATALMVLGAQAGCAHAERHGLDALFVVRDGDALRTIGCGAFADA
GPAG
>Mature_403_residues
SKTSIEWSPGARLNRCRASGATMGTRYGAQFYAPPTADARAIAAALDAAVRAVDAQMSNWKADSDLSRLNRATPGSWTPI
CANLAAVLVRAREIGRETDNAFNIGVGTLVDRWGFGPGAAANRQADNERAANRQAAGRHTVARRTVARHMVARHTVDRHT
ADRQTADRQTKDGRTPDRQPARPAGPANGLSGAIDARRRASILRGPVPSPCRPIDELLEVDVARGRVRRLADVAFDLCGI
AKGFGVDELARVLDRHGIGAWLVGIDGELRARGCKPDGSPWAIALEAPDYGRRGAMGAIDLVDAAVATSGDYRHWADFGG
ERLSHTMDPRAGAPLRGDIASVTVVAPTCTDADAYATALMVLGAQAGCAHAERHGLDALFVVRDGDALRTIGCGAFADAG
PAG

Specific function: Involved in the conversion of aminoimidazole ribotide (AIR), a purine intermediate, to the 4-amino-5-hydroxymethyl-2- methyl pyrimidine (HMP) moiety of thiamine [H]

COG id: COG1477

COG function: function code H; Membrane-associated lipoprotein involved in thiamine biosynthesis

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ApbE family [H]

Homologues:

Organism=Escherichia coli, GI1788543, Length=169, Percent_Identity=35.5029585798817, Blast_Score=135, Evalue=5e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003374 [H]

Pfam domain/function: PF02424 ApbE [H]

EC number: NA

Molecular weight: Translated: 42616; Mature: 42485

Theoretical pI: Translated: 8.95; Mature: 8.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKTSIEWSPGARLNRCRASGATMGTRYGAQFYAPPTADARAIAAALDAAVRAVDAQMSN
CCCCCCCCCCCCHHHHHHCCCCCCCHHCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHC
WKADSDLSRLNRATPGSWTPICANLAAVLVRAREIGRETDNAFNIGVGTLVDRWGFGPGA
CCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEECCHHHHHHHCCCCCCC
AANRQADNERAANRQAAGRHTVARRTVARHMVARHTVDRHTADRQTADRQTKDGRTPDRQ
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
PARPAGPANGLSGAIDARRRASILRGPVPSPCRPIDELLEVDVARGRVRRLADVAFDLCG
CCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IAKGFGVDELARVLDRHGIGAWLVGIDGELRARGCKPDGSPWAIALEAPDYGRRGAMGAI
HHCCCCHHHHHHHHHHCCCCEEEEECCCCHHCCCCCCCCCCEEEEEECCCCCCCCCCCHH
DLVDAAVATSGDYRHWADFGGERLSHTMDPRAGAPLRGDIASVTVVAPTCTDADAYATAL
HHHHHHHHCCCCCHHHHHCCHHHHHHCCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHH
MVLGAQAGCAHAERHGLDALFVVRDGDALRTIGCGAFADAGPAG
HHHHCCCCHHHHHHCCCCEEEEEECCCCEEEECCCCCCCCCCCC
>Mature Secondary Structure 
SKTSIEWSPGARLNRCRASGATMGTRYGAQFYAPPTADARAIAAALDAAVRAVDAQMSN
CCCCCCCCCCCHHHHHHCCCCCCCHHCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHC
WKADSDLSRLNRATPGSWTPICANLAAVLVRAREIGRETDNAFNIGVGTLVDRWGFGPGA
CCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEECCHHHHHHHCCCCCCC
AANRQADNERAANRQAAGRHTVARRTVARHMVARHTVDRHTADRQTADRQTKDGRTPDRQ
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
PARPAGPANGLSGAIDARRRASILRGPVPSPCRPIDELLEVDVARGRVRRLADVAFDLCG
CCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IAKGFGVDELARVLDRHGIGAWLVGIDGELRARGCKPDGSPWAIALEAPDYGRRGAMGAI
HHCCCCHHHHHHHHHHCCCCEEEEECCCCHHCCCCCCCCCCEEEEEECCCCCCCCCCCHH
DLVDAAVATSGDYRHWADFGGERLSHTMDPRAGAPLRGDIASVTVVAPTCTDADAYATAL
HHHHHHHHCCCCCHHHHHCCHHHHHHCCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHH
MVLGAQAGCAHAERHGLDALFVVRDGDALRTIGCGAFADAGPAG
HHHHCCCCHHHHHHCCCCEEEEEECCCCEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]