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The map label for this gene is frzE [H]

Identifier: 126445509

GI number: 126445509

Start: 2568444

End: 2571038

Strand: Reverse

Name: frzE [H]

Synonym: BURPS668_A2683

Alternate gene names: 126445509

Gene position: 2571038-2568444 (Counterclockwise)

Preceding gene: 126445176

Following gene: 126442726

Centisome position: 82.21

GC content: 71.91

Gene sequence:

>2595_bases
ATGAGCACCGACGACGATTTCGGCCGCGCGTCGCTGCTCGAGCTGTTTCGCGAGGAGACGCACACGCAGACGCAGGCGCT
GTCCGAGCGGCTGCTCGCGCTCGAGCGCGGCGCGCAGGATGCGGCGACGCTCGAGGCGTGCATGCGCGCCGCGCATTCGC
TCAAGGGCGCGGCGCGCATCGTCGGCGTGCCGCAGGGCGTCGACATCGCGGGGCGGATGGAGGATTGCTTCGTCGCCGCG
CAGCACGGCCGGCAGCCGCTCACGCCGTGCCATGTCGACGCGCTGCTCACGGGCGTCGATCTGCTCGTGCGCGTCGGCGA
TCCGCAGACGGCGGCGTCGGTTGCGCCGCACGAGATCGACGCGTTCGCGGCGGCGCTCGCGGCCGCGGATGCGGGCGTGC
GCCCAGGCGCCGATGCGCGCGGAGCGAACGCATACGAGAGCGACGGCAACGCGCACGAACGCGGCGGCGCGGCGCGCGCA
AGCGTCGCCGCCGCACCGGGCGAGGCCGCCGATGCGTCGCGCGAAAGCGGCGCGCGTGAGGCGGGCGGCTCGAATCGCGC
GGGCGCGGCGGCGGGCGCCGCCGATGTCCGCGCGAGCGCGGATGCCGGCGACGCGCGCGGTGCGAGCGACATGCGCGACG
TGCGGCACACGGCCGGTGCACGCGGCGCGAACCGTTCGACGGAGGTTTTCGGCGCGGGCGAAGCGACCGGCATCGGCGCG
TCGACCCATGCGAATGACGCGAACGGCATGAACGCCACGAACCTCGCGACATCGGCGGCCCATCCGCCGCGCGGCGCATT
CGCCGCGGCGCACGACGCGCCGCCGTCTTCCGCCCCGTCCGACGCGCCGCGCGCGCCGAGCCAGATGCGCCGCGTGCGCG
CCGATACGCTGAACCGGCTGCTGAGCCTGTCCGGCGAATCGCTCGTCGAGTCGCGCTGGCTGAAGCCGTTCGCCGAATCG
ATGCTGCGCGTGAAGCGCGCGCAGCGCGACGCGGCCCGCTCGCTCGATTCGGCCGTCGAGGCGCTCGCCGACGACGCGGA
CCCGCGCGTGCGCGGCGCGCTCAACGAGGCGCGGCAGATGTTCACCGATCTGCAGCGCACGTTCGCCGCGCGGCTCGACG
AGCTCGACCGCTTCGAGCGCCGCAGCTCGCACATCGCCGAGCAACTGTACGACGAGGCGCTGCAATGCCGGATGCGCCCG
TTCGGCGACGCGACGCGCGCCTACCCGCGCGTCGTGCGCGATCTCGCCCGCTCGCTCGGCAAACGTGTGCGCTTCTCGAT
CGTCGGCGAAGCGACGCAGGTCGATCGCGACATCCTCGACATGCTCGACGCGCCGCTCGGCCATTTGCTGCGCAACGCGC
TCGATCACGGCGTCGAGCCGCCCGAGGTGCGGCTCGCGCGCGGCAAGCCGGCGGAGGCCACCATCACGCTCGAGGCGCGG
CACAGCGCCGGCTCGCTGCTCGTCAGCGTGAGCGACGACGGCCCCGGCGCCGATCTCGCCGCGGTGCGCGCGGCGATCGT
GCGCCACCACCTGACCGACGAGGATACGGCCGCGCGCCTGTCCGATCAGGAACTGCTCGAATTCCTGCTGCTGCCCGGCT
TCTCGATGCGCGAGCGGGTGACCGACGTGTCGGGCCGCGGCGTCGGCCTCGACGCGGTGCAGGAAATGGTGAAGTCGGTG
CGCGGCGCGGTGCGCATCTTCAACGAGCCGGGCCTCGGCATGCGCTTCGTGCTGCAGTTGCCGCTCACGCTGTCGGTGAT
CCGCAGCCTGATCGTCGACGTCGGCGGCGAGCCGTACGCGTTCCCGCTCGTGCAGGTGCGCCGCACGCTCGAGCTCGAGC
GCGCGGACATCGACGTGCTCGAAGGCCAGCAGCACTTTCCGCTCGACGATCGCCGCGTCGGCCTCGTCACCGCGCATCAG
CTGCTCGACGCGGGCGAGCTCGACGAAAGCCGGCCGGCGACGGCCGTCGTCGTCGTCGGAGGCGAGCCGGAAACCTACGG
CGTCGCGGTGGACCGCTTCCTCGGCGAGCGGATGCTCGTGGTGCAGCCGTTAGACGGACGCCTCAACAAAATTCAGAACA
TTGCGGCGGGCGCTTTGCTGGAAAATGGCGATCCGGTGCTGATCGTCGACGTCGAGGATCTGATCCGCTCGATCGACAAG
CTGATTCGCGGCGGCCAGCTCGCGAAGGTGCGGCGCGGCGATCGGGACGCGCTCGCGCGGCGCGCGAAGCGCGTGCTCGT
GGTCGACGATTCGCTGACCGTGCGCGAGCTCGAGCGCAAGCTGCTCGAGAAGCGCGGCTACGACGTGACGATCGCGATCG
ACGGCATGGACGGCTGGAACGCGATCCGCGGCGACGCGTTCGATCTCGTCGTCACCGACATCGACATGCCGCGCATGGAC
GGCATCGAGCTCGTCACGCTGATCAAGGGCGATCCGCTGCTCAAATCGGTGCCCGTGATGATCGTGTCGTACAAGGATCG
CGACGAGGACCGGCGGCGCGGGCTCGAAGCGGGCGCCGACTATTACCTGGCGAAGGGCGGCTTCCATGACGAGGCGTTGC
TCGACGCCGTGCACGACCTGATTGGGGACGCGTAG

Upstream 100 bases:

>100_bases
CGGGCGCCGTGCATTCGCGCGGCGTGTTCGCGTGGCGCGGCAAGTCGATCGGCCTGCTCGACGAAGATCGCCTGTTCGAT
TCGCTGACGCGGAGCCTGCG

Downstream 100 bases:

>100_bases
AAAGCCATGAACATCGGCATCGTCAACGACTTGCCGCTCGCCGTCGAGGCGCTGCGCCGCACGATCGCGCTGCGGCCCGA
GCACCGCGTGCTGTGGGTCG

Product: chemotaxis histidine kinase/response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 864; Mature: 863

Protein sequence:

>864_residues
MSTDDDFGRASLLELFREETHTQTQALSERLLALERGAQDAATLEACMRAAHSLKGAARIVGVPQGVDIAGRMEDCFVAA
QHGRQPLTPCHVDALLTGVDLLVRVGDPQTAASVAPHEIDAFAAALAAADAGVRPGADARGANAYESDGNAHERGGAARA
SVAAAPGEAADASRESGAREAGGSNRAGAAAGAADVRASADAGDARGASDMRDVRHTAGARGANRSTEVFGAGEATGIGA
STHANDANGMNATNLATSAAHPPRGAFAAAHDAPPSSAPSDAPRAPSQMRRVRADTLNRLLSLSGESLVESRWLKPFAES
MLRVKRAQRDAARSLDSAVEALADDADPRVRGALNEARQMFTDLQRTFAARLDELDRFERRSSHIAEQLYDEALQCRMRP
FGDATRAYPRVVRDLARSLGKRVRFSIVGEATQVDRDILDMLDAPLGHLLRNALDHGVEPPEVRLARGKPAEATITLEAR
HSAGSLLVSVSDDGPGADLAAVRAAIVRHHLTDEDTAARLSDQELLEFLLLPGFSMRERVTDVSGRGVGLDAVQEMVKSV
RGAVRIFNEPGLGMRFVLQLPLTLSVIRSLIVDVGGEPYAFPLVQVRRTLELERADIDVLEGQQHFPLDDRRVGLVTAHQ
LLDAGELDESRPATAVVVVGGEPETYGVAVDRFLGERMLVVQPLDGRLNKIQNIAAGALLENGDPVLIVDVEDLIRSIDK
LIRGGQLAKVRRGDRDALARRAKRVLVVDDSLTVRELERKLLEKRGYDVTIAIDGMDGWNAIRGDAFDLVVTDIDMPRMD
GIELVTLIKGDPLLKSVPVMIVSYKDRDEDRRRGLEAGADYYLAKGGFHDEALLDAVHDLIGDA

Sequences:

>Translated_864_residues
MSTDDDFGRASLLELFREETHTQTQALSERLLALERGAQDAATLEACMRAAHSLKGAARIVGVPQGVDIAGRMEDCFVAA
QHGRQPLTPCHVDALLTGVDLLVRVGDPQTAASVAPHEIDAFAAALAAADAGVRPGADARGANAYESDGNAHERGGAARA
SVAAAPGEAADASRESGAREAGGSNRAGAAAGAADVRASADAGDARGASDMRDVRHTAGARGANRSTEVFGAGEATGIGA
STHANDANGMNATNLATSAAHPPRGAFAAAHDAPPSSAPSDAPRAPSQMRRVRADTLNRLLSLSGESLVESRWLKPFAES
MLRVKRAQRDAARSLDSAVEALADDADPRVRGALNEARQMFTDLQRTFAARLDELDRFERRSSHIAEQLYDEALQCRMRP
FGDATRAYPRVVRDLARSLGKRVRFSIVGEATQVDRDILDMLDAPLGHLLRNALDHGVEPPEVRLARGKPAEATITLEAR
HSAGSLLVSVSDDGPGADLAAVRAAIVRHHLTDEDTAARLSDQELLEFLLLPGFSMRERVTDVSGRGVGLDAVQEMVKSV
RGAVRIFNEPGLGMRFVLQLPLTLSVIRSLIVDVGGEPYAFPLVQVRRTLELERADIDVLEGQQHFPLDDRRVGLVTAHQ
LLDAGELDESRPATAVVVVGGEPETYGVAVDRFLGERMLVVQPLDGRLNKIQNIAAGALLENGDPVLIVDVEDLIRSIDK
LIRGGQLAKVRRGDRDALARRAKRVLVVDDSLTVRELERKLLEKRGYDVTIAIDGMDGWNAIRGDAFDLVVTDIDMPRMD
GIELVTLIKGDPLLKSVPVMIVSYKDRDEDRRRGLEAGADYYLAKGGFHDEALLDAVHDLIGDA
>Mature_863_residues
STDDDFGRASLLELFREETHTQTQALSERLLALERGAQDAATLEACMRAAHSLKGAARIVGVPQGVDIAGRMEDCFVAAQ
HGRQPLTPCHVDALLTGVDLLVRVGDPQTAASVAPHEIDAFAAALAAADAGVRPGADARGANAYESDGNAHERGGAARAS
VAAAPGEAADASRESGAREAGGSNRAGAAAGAADVRASADAGDARGASDMRDVRHTAGARGANRSTEVFGAGEATGIGAS
THANDANGMNATNLATSAAHPPRGAFAAAHDAPPSSAPSDAPRAPSQMRRVRADTLNRLLSLSGESLVESRWLKPFAESM
LRVKRAQRDAARSLDSAVEALADDADPRVRGALNEARQMFTDLQRTFAARLDELDRFERRSSHIAEQLYDEALQCRMRPF
GDATRAYPRVVRDLARSLGKRVRFSIVGEATQVDRDILDMLDAPLGHLLRNALDHGVEPPEVRLARGKPAEATITLEARH
SAGSLLVSVSDDGPGADLAAVRAAIVRHHLTDEDTAARLSDQELLEFLLLPGFSMRERVTDVSGRGVGLDAVQEMVKSVR
GAVRIFNEPGLGMRFVLQLPLTLSVIRSLIVDVGGEPYAFPLVQVRRTLELERADIDVLEGQQHFPLDDRRVGLVTAHQL
LDAGELDESRPATAVVVVGGEPETYGVAVDRFLGERMLVVQPLDGRLNKIQNIAAGALLENGDPVLIVDVEDLIRSIDKL
IRGGQLAKVRRGDRDALARRAKRVLVVDDSLTVRELERKLLEKRGYDVTIAIDGMDGWNAIRGDAFDLVVTDIDMPRMDG
IELVTLIKGDPLLKSVPVMIVSYKDRDEDRRRGLEAGADYYLAKGGFHDEALLDAVHDLIGDA

Specific function: FrzE is involved in a sensory transduction pathway that controls the frequency at which cells reverse their gliding direction. FrzE seems to be capable of autophosphorylating itself on an histidine residue and then to transfer that group to an aspartate r

COG id: COG0643

COG function: function code NT; Chemotaxis protein histidine kinase and related kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788197, Length=696, Percent_Identity=27.0114942528736, Blast_Score=200, Evalue=4e-52,
Organism=Escherichia coli, GI1788191, Length=109, Percent_Identity=34.8623853211009, Blast_Score=72, Evalue=2e-13,
Organism=Escherichia coli, GI1786599, Length=104, Percent_Identity=33.6538461538462, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR002545
- InterPro:   IPR011006
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR005467
- InterPro:   IPR001789 [H]

Pfam domain/function: PF01584 CheW; PF02518 HATPase_c; PF01627 Hpt; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 92501; Mature: 92370

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: PS50851 CHEW ; PS50894 HPT ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTDDDFGRASLLELFREETHTQTQALSERLLALERGAQDAATLEACMRAAHSLKGAARI
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHE
VGVPQGVDIAGRMEDCFVAAQHGRQPLTPCHVDALLTGVDLLVRVGDPQTAASVAPHEID
EECCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHEECCCCCHHHHCCCHHHH
AFAAALAAADAGVRPGADARGANAYESDGNAHERGGAARASVAAAPGEAADASRESGARE
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHCCCCHHHHHCCCCCCHHCCHHHCCCHH
AGGSNRAGAAAGAADVRASADAGDARGASDMRDVRHTAGARGANRSTEVFGAGEATGIGA
CCCCCCCCCCCCCHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCC
STHANDANGMNATNLATSAAHPPRGAFAAAHDAPPSSAPSDAPRAPSQMRRVRADTLNRL
CCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
LSLSGESLVESRWLKPFAESMLRVKRAQRDAARSLDSAVEALADDADPRVRGALNEARQM
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
FTDLQRTFAARLDELDRFERRSSHIAEQLYDEALQCRMRPFGDATRAYPRVVRDLARSLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
KRVRFSIVGEATQVDRDILDMLDAPLGHLLRNALDHGVEPPEVRLARGKPAEATITLEAR
HHEEEEEECCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCEEEECCCCCCEEEEEEEC
HSAGSLLVSVSDDGPGADLAAVRAAIVRHHLTDEDTAARLSDQELLEFLLLPGFSMRERV
CCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHCCCCCHHHHH
TDVSGRGVGLDAVQEMVKSVRGAVRIFNEPGLGMRFVLQLPLTLSVIRSLIVDVGGEPYA
HCCCCCCCCHHHHHHHHHHHHHHHEEECCCCCCEEHHHHHHHHHHHHHHHHHHCCCCCCC
FPLVQVRRTLELERADIDVLEGQQHFPLDDRRVGLVTAHQLLDAGELDESRPATAVVVVG
HHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCEEEEEEC
GEPETYGVAVDRFLGERMLVVQPLDGRLNKIQNIAAGALLENGDPVLIVDVEDLIRSIDK
CCCCHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHEEECCCCEEEEEHHHHHHHHHH
LIRGGQLAKVRRGDRDALARRAKRVLVVDDSLTVRELERKLLEKRGYDVTIAIDGMDGWN
HHCCCCCHHHHCCCHHHHHHHHCEEEEECCCCHHHHHHHHHHHHCCCEEEEEEECCCCCC
AIRGDAFDLVVTDIDMPRMDGIELVTLIKGDPLLKSVPVMIVSYKDRDEDRRRGLEAGAD
CCCCCCEEEEEEECCCCCCCCCEEEEEECCCCHHHCCCEEEEEECCCCHHHHCCHHCCCC
YYLAKGGFHDEALLDAVHDLIGDA
EEEECCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure 
STDDDFGRASLLELFREETHTQTQALSERLLALERGAQDAATLEACMRAAHSLKGAARI
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHE
VGVPQGVDIAGRMEDCFVAAQHGRQPLTPCHVDALLTGVDLLVRVGDPQTAASVAPHEID
EECCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHEECCCCCHHHHCCCHHHH
AFAAALAAADAGVRPGADARGANAYESDGNAHERGGAARASVAAAPGEAADASRESGARE
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHCCCCHHHHHCCCCCCHHCCHHHCCCHH
AGGSNRAGAAAGAADVRASADAGDARGASDMRDVRHTAGARGANRSTEVFGAGEATGIGA
CCCCCCCCCCCCCHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCC
STHANDANGMNATNLATSAAHPPRGAFAAAHDAPPSSAPSDAPRAPSQMRRVRADTLNRL
CCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
LSLSGESLVESRWLKPFAESMLRVKRAQRDAARSLDSAVEALADDADPRVRGALNEARQM
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
FTDLQRTFAARLDELDRFERRSSHIAEQLYDEALQCRMRPFGDATRAYPRVVRDLARSLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
KRVRFSIVGEATQVDRDILDMLDAPLGHLLRNALDHGVEPPEVRLARGKPAEATITLEAR
HHEEEEEECCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCEEEECCCCCCEEEEEEEC
HSAGSLLVSVSDDGPGADLAAVRAAIVRHHLTDEDTAARLSDQELLEFLLLPGFSMRERV
CCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHCCCCCHHHHH
TDVSGRGVGLDAVQEMVKSVRGAVRIFNEPGLGMRFVLQLPLTLSVIRSLIVDVGGEPYA
HCCCCCCCCHHHHHHHHHHHHHHHEEECCCCCCEEHHHHHHHHHHHHHHHHHHCCCCCCC
FPLVQVRRTLELERADIDVLEGQQHFPLDDRRVGLVTAHQLLDAGELDESRPATAVVVVG
HHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCEEEEEEC
GEPETYGVAVDRFLGERMLVVQPLDGRLNKIQNIAAGALLENGDPVLIVDVEDLIRSIDK
CCCCHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHEEECCCCEEEEEHHHHHHHHHH
LIRGGQLAKVRRGDRDALARRAKRVLVVDDSLTVRELERKLLEKRGYDVTIAIDGMDGWN
HHCCCCCHHHHCCCHHHHHHHHCEEEEECCCCHHHHHHHHHHHHCCCEEEEEEECCCCCC
AIRGDAFDLVVTDIDMPRMDGIELVTLIKGDPLLKSVPVMIVSYKDRDEDRRRGLEAGAD
CCCCCCEEEEEEECCCCCCCCCEEEEEECCCCHHHCCCEEEEEECCCCHHHHCCHHCCCC
YYLAKGGFHDEALLDAVHDLIGDA
EEEECCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2165608; 2123853 [H]