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The map label for this gene is czcC [H]

Identifier: 126445487

GI number: 126445487

Start: 1468926

End: 1470284

Strand: Reverse

Name: czcC [H]

Synonym: BURPS668_A1527

Alternate gene names: 126445487

Gene position: 1470284-1468926 (Counterclockwise)

Preceding gene: 126444891

Following gene: 126443033

Centisome position: 47.01

GC content: 74.76

Gene sequence:

>1359_bases
GTGTCGGCCGCGATCGCGGCGTCGGCGGGGCCGGCGCAAGCGCAGCCCGCGCCGGCCCCGTCCGCGCCCCACGGCCCGGC
CGCCGCACCGCCGGACGCCCGCGCGGCCTCCGTCTCCGTCACGCCCGCCGTCTCTCCCGCACCGATTTCGACTTCGACTG
TGTCCGTCGCGCCGCCCGCGCTGTCGCTCGACGACGCACTGGCCCTAGCCGCAGCGAACAACCCGCTGCTGAAAAGCGCG
CGATCGAGCGCCGACGCATCCGTCGGCGCGCTCGTCCAGGCGGGCGCGCGTCCGAATCCGACCGTGTCGTTCCTGCAGGA
AGGGTTCGGGCGGCAGGAGCGCACGACGACCGCCGTCGTCAGCCAGCCGATCGAGCTCGGCGGCAAGCGGCGCTCGCGCG
TCGACGCCGCATCGTACGGCCGCGAATCCGCGCTCGCGTCGCTCGACGGCCGCGCGGCCGCGCTGCGCGCCGACGTGACG
GGCGCGTTCTACGGCGTGCTCGCCGCGCAGCGCCAGTTGCAGGTCGCCGACGAATCGGCCGCGATCGCCGCGCGCTCGGC
CGACATGGCCGACAAGCGCGCCCGCGCGGGCAAGGTGTCGCCCGTCGAGGCGACGAAGGCGCGCGTCGCGCAGACGGCCG
CGCAGATCGAGCTGTCGAACGCGCAAACGCGGGTGGCGGCGGCGCTCGCGCGGCTCGCGAACGCAACAGGCAGCGCCGAC
GTGCGCGGGCGCGCCGCGTCGGGCGACCTCGACGCGTTGCCCGCCGCCGAGCCGCTGCCGCAACTGCTCGGCCGGCTCGA
CGACGCGCCGCTCGCGCGCGCGGCGAAAGCCGACATGCTGCGCACGAACGCGCAGATCGCGATCGAGCGCGCGAAGCGCG
TGCCGGACATCACGGTGAGCGCGGGCGTCAAGCATGTCGTCACGGGCGGCGCGCCGGACAACCAGGCGGTCGTCGGCATC
TCGATTCCGCTGCCGCTCTTCGACACGAACAGGGGCGCGCTGCTCGAAGCCGTCCACAACGCGGCGAAGGCAAGCGCCGA
TTTCGACGCCGAGCGCGCGCGGCTGCGGCTCGATCTCACCCAGGCCTACGCGAACTACGAGCGCGCGACGGGCGAGGCGC
GGCGGCTGAAGGCCGACGTGCTGCCCGCCGCGCGGCAGTCGCTCGACGCGATGTCGCGCGGCTACCAGCTCGGCAAGTTC
GGCTTTCTCGACGTGCTCGACGCGCAGCGCACGCTGTTCGATGCGCAGTCGCGCTACGTGCAGGCGCTCGCCGACGCGCA
TCAGTCGTATGCGGACATCGAGCGCGTCGTCGGCGCGCCGTCGCGCGACGTTTCCCGCCCCCTCGCCCAACTTCGCTGA

Upstream 100 bases:

>100_bases
GTCATGTTCGCCTCATGTTTGCATTGCGGCACGTCCGTAGCATCGATCGCGTTTCACCGGAACTCGATCACTCATGCCCA
AGCGTATCTTCGCCGCACTC

Downstream 100 bases:

>100_bases
AGAACTCGCCATGCAACGCAAGCCCCTGATTCTCGCCGGCGCGGCCGCGGCCGGCGCTCTCGCCATCGTGCTGGCGCTCG
CGCGCGCGCCGTCCACGTCG

Product: cobalt-zinc-cadmium resistance protein CzcC

Products: NA

Alternate protein names: Cation efflux system protein CzcC [H]

Number of amino acids: Translated: 452; Mature: 451

Protein sequence:

>452_residues
MSAAIAASAGPAQAQPAPAPSAPHGPAAAPPDARAASVSVTPAVSPAPISTSTVSVAPPALSLDDALALAAANNPLLKSA
RSSADASVGALVQAGARPNPTVSFLQEGFGRQERTTTAVVSQPIELGGKRRSRVDAASYGRESALASLDGRAAALRADVT
GAFYGVLAAQRQLQVADESAAIAARSADMADKRARAGKVSPVEATKARVAQTAAQIELSNAQTRVAAALARLANATGSAD
VRGRAASGDLDALPAAEPLPQLLGRLDDAPLARAAKADMLRTNAQIAIERAKRVPDITVSAGVKHVVTGGAPDNQAVVGI
SIPLPLFDTNRGALLEAVHNAAKASADFDAERARLRLDLTQAYANYERATGEARRLKADVLPAARQSLDAMSRGYQLGKF
GFLDVLDAQRTLFDAQSRYVQALADAHQSYADIERVVGAPSRDVSRPLAQLR

Sequences:

>Translated_452_residues
MSAAIAASAGPAQAQPAPAPSAPHGPAAAPPDARAASVSVTPAVSPAPISTSTVSVAPPALSLDDALALAAANNPLLKSA
RSSADASVGALVQAGARPNPTVSFLQEGFGRQERTTTAVVSQPIELGGKRRSRVDAASYGRESALASLDGRAAALRADVT
GAFYGVLAAQRQLQVADESAAIAARSADMADKRARAGKVSPVEATKARVAQTAAQIELSNAQTRVAAALARLANATGSAD
VRGRAASGDLDALPAAEPLPQLLGRLDDAPLARAAKADMLRTNAQIAIERAKRVPDITVSAGVKHVVTGGAPDNQAVVGI
SIPLPLFDTNRGALLEAVHNAAKASADFDAERARLRLDLTQAYANYERATGEARRLKADVLPAARQSLDAMSRGYQLGKF
GFLDVLDAQRTLFDAQSRYVQALADAHQSYADIERVVGAPSRDVSRPLAQLR
>Mature_451_residues
SAAIAASAGPAQAQPAPAPSAPHGPAAAPPDARAASVSVTPAVSPAPISTSTVSVAPPALSLDDALALAAANNPLLKSAR
SSADASVGALVQAGARPNPTVSFLQEGFGRQERTTTAVVSQPIELGGKRRSRVDAASYGRESALASLDGRAAALRADVTG
AFYGVLAAQRQLQVADESAAIAARSADMADKRARAGKVSPVEATKARVAQTAAQIELSNAQTRVAAALARLANATGSADV
RGRAASGDLDALPAAEPLPQLLGRLDDAPLARAAKADMLRTNAQIAIERAKRVPDITVSAGVKHVVTGGAPDNQAVVGIS
IPLPLFDTNRGALLEAVHNAAKASADFDAERARLRLDLTQAYANYERATGEARRLKADVLPAARQSLDAMSRGYQLGKFG
FLDVLDAQRTLFDAQSRYVQALADAHQSYADIERVVGAPSRDVSRPLAQLR

Specific function: CzcC protein appears to modify the specificity of the system, perhaps by acting on the CzcB protein. When the CzcC protein is added to CzcA and CzcB, the efflux system gains specificity for cadmium and cobalt [H]

COG id: COG1538

COG function: function code MU; Outer membrane protein

Gene ontology:

Cell location: Cell outer membrane (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003423 [H]

Pfam domain/function: PF02321 OEP [H]

EC number: NA

Molecular weight: Translated: 46475; Mature: 46343

Theoretical pI: Translated: 10.17; Mature: 10.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAAIAASAGPAQAQPAPAPSAPHGPAAAPPDARAASVSVTPAVSPAPISTSTVSVAPPA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCEEEECCCC
LSLDDALALAAANNPLLKSARSSADASVGALVQAGARPNPTVSFLQEGFGRQERTTTAVV
CCHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHCCCCCCCHHHHHHHHCCCCHHHHHHHH
SQPIELGGKRRSRVDAASYGRESALASLDGRAAALRADVTGAFYGVLAAQRQLQVADESA
HCHHHHCCCHHHHCCHHHCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
AIAARSADMADKRARAGKVSPVEATKARVAQTAAQIELSNAQTRVAAALARLANATGSAD
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHCCCCCCC
VRGRAASGDLDALPAAEPLPQLLGRLDDAPLARAAKADMLRTNAQIAIERAKRVPDITVS
CCCCCCCCCCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHHHHHCCCCEEHH
AGVKHVVTGGAPDNQAVVGISIPLPLFDTNRGALLEAVHNAAKASADFDAERARLRLDLT
CCCCEEEECCCCCCCEEEEEEECCCEEECCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
QAYANYERATGEARRLKADVLPAARQSLDAMSRGYQLGKFGFLDVLDAQRTLFDAQSRYV
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHH
QALADAHQSYADIERVVGAPSRDVSRPLAQLR
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCC
>Mature Secondary Structure 
SAAIAASAGPAQAQPAPAPSAPHGPAAAPPDARAASVSVTPAVSPAPISTSTVSVAPPA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCEEEECCCC
LSLDDALALAAANNPLLKSARSSADASVGALVQAGARPNPTVSFLQEGFGRQERTTTAVV
CCHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHCCCCCCCHHHHHHHHCCCCHHHHHHHH
SQPIELGGKRRSRVDAASYGRESALASLDGRAAALRADVTGAFYGVLAAQRQLQVADESA
HCHHHHCCCHHHHCCHHHCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
AIAARSADMADKRARAGKVSPVEATKARVAQTAAQIELSNAQTRVAAALARLANATGSAD
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHCCCCCCC
VRGRAASGDLDALPAAEPLPQLLGRLDDAPLARAAKADMLRTNAQIAIERAKRVPDITVS
CCCCCCCCCCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHHHHHCCCCEEHH
AGVKHVVTGGAPDNQAVVGISIPLPLFDTNRGALLEAVHNAAKASADFDAERARLRLDLT
CCCCEEEECCCCCCCEEEEEEECCCEEECCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
QAYANYERATGEARRLKADVLPAARQSLDAMSRGYQLGKFGFLDVLDAQRTLFDAQSRYV
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHH
QALADAHQSYADIERVVGAPSRDVSRPLAQLR
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2678100; 7766206 [H]