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The map label for this gene is uvrY [H]

Identifier: 126445165

GI number: 126445165

Start: 1085612

End: 1086250

Strand: Reverse

Name: uvrY [H]

Synonym: BURPS668_A1132

Alternate gene names: 126445165

Gene position: 1086250-1085612 (Counterclockwise)

Preceding gene: 126444250

Following gene: 126443559

Centisome position: 34.73

GC content: 68.54

Gene sequence:

>639_bases
ATGATCAGGCTGTTGATGGTGGACCGTCACGCGGTATTGCGCGACGGCTTGCGACACATACTCGAAAAATCCGGCGAATT
CGAAATCGACGGCGAGGCGGCCGACGCCGCATCCGCGTTCGAGCTCGCCGGCCGGGGCTGCGCCGAGATCGCGCTCCTCG
ATCAAACCACGCTCGGCCGCGAATGCGCGGAGCTGATCCGGCACCTCCGCCGCGCGGCGCCATCGACGCGCATTCTCGTG
CTCGCCGCGCGCGCGAGTCAGCGGCACGCGGCCGCGGCGTTCCAGGCCGGCGCGTCCGGCTACCTGACGAAGCAAAGCGG
CTGCGAGGAATTGCTCGCCGCGCTGCGCAAGATCGCGGCGGGCGGCGTGTACGTCAGCATGCACGTGGCCGAGCAGTTCG
CGGAAAACCTGCATTCGCCGTCAGATGCGCCGCCGCACGAGCGGCTGTCCAGACGCGAGTTCGAGGTGTTCCGCCGCCTC
GCGGCCGGCGACACGCCCGCCGACATCGCGCAAGCGCTCGGGATCAGCGCGAAAACCGTCAGGATCTACAAGGCGCACGT
GCTCGACAAGCTGGAACTGCCGAACGAAACGGCGCTCGTGCGATACGCGGTCGCGCACCGGATCGGCGATCCGCTGTGA

Upstream 100 bases:

>100_bases
GGATCGCCGCATGCGCTCGCGCGCCGCCGCGACGCGGCGCGCCCGCCGAGCGCCGTTACGCGATGCCCAATAAGCAGGTA
AGCGCTACGAGGCTGCGCCG

Downstream 100 bases:

>100_bases
GCGGCCATGATCTGCGTCGCGCCGGAGATCGCCGCCGCGCGCCGGCGGTTCGGTCACGCGGCGCCGATTTGCCGATTTGC
CGGCTGCCGGCTGCCGGCTG

Product: LuxR family DNA-binding response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 212; Mature: 212

Protein sequence:

>212_residues
MIRLLMVDRHAVLRDGLRHILEKSGEFEIDGEAADAASAFELAGRGCAEIALLDQTTLGRECAELIRHLRRAAPSTRILV
LAARASQRHAAAAFQAGASGYLTKQSGCEELLAALRKIAAGGVYVSMHVAEQFAENLHSPSDAPPHERLSRREFEVFRRL
AAGDTPADIAQALGISAKTVRIYKAHVLDKLELPNETALVRYAVAHRIGDPL

Sequences:

>Translated_212_residues
MIRLLMVDRHAVLRDGLRHILEKSGEFEIDGEAADAASAFELAGRGCAEIALLDQTTLGRECAELIRHLRRAAPSTRILV
LAARASQRHAAAAFQAGASGYLTKQSGCEELLAALRKIAAGGVYVSMHVAEQFAENLHSPSDAPPHERLSRREFEVFRRL
AAGDTPADIAQALGISAKTVRIYKAHVLDKLELPNETALVRYAVAHRIGDPL
>Mature_212_residues
MIRLLMVDRHAVLRDGLRHILEKSGEFEIDGEAADAASAFELAGRGCAEIALLDQTTLGRECAELIRHLRRAAPSTRILV
LAARASQRHAAAAFQAGASGYLTKQSGCEELLAALRKIAAGGVYVSMHVAEQFAENLHSPSDAPPHERLSRREFEVFRRL
AAGDTPADIAQALGISAKTVRIYKAHVLDKLELPNETALVRYAVAHRIGDPL

Specific function: Member of the two-component regulatory system UvrY/BarA involved in the regulation of carbon metabolism via the CsrA/CsrB regulatory system. UvrY activates the transcription of the untranslated csrB RNA and of barA, in an autoregulatory loop. Mediates the

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788222, Length=207, Percent_Identity=28.9855072463768, Blast_Score=106, Evalue=1e-24,
Organism=Escherichia coli, GI1788521, Length=196, Percent_Identity=33.1632653061224, Blast_Score=100, Evalue=9e-23,
Organism=Escherichia coli, GI1790102, Length=202, Percent_Identity=28.7128712871287, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1788712, Length=205, Percent_Identity=26.8292682926829, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1786747, Length=200, Percent_Identity=22.5, Blast_Score=77, Evalue=8e-16,
Organism=Escherichia coli, GI1787473, Length=182, Percent_Identity=28.5714285714286, Blast_Score=71, Evalue=5e-14,
Organism=Escherichia coli, GI1788546, Length=204, Percent_Identity=25.4901960784314, Blast_Score=63, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 23006; Mature: 23006

Theoretical pI: Translated: 7.70; Mature: 7.70

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRLLMVDRHAVLRDGLRHILEKSGEFEIDGEAADAASAFELAGRGCAEIALLDQTTLGR
CEEEEEEHHHHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHCCCHHHEEECCHHHHHH
ECAELIRHLRRAAPSTRILVLAARASQRHAAAAFQAGASGYLTKQSGCEELLAALRKIAA
HHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHC
GGVYVSMHVAEQFAENLHSPSDAPPHERLSRREFEVFRRLAAGDTPADIAQALGISAKTV
CCCEEHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHH
RIYKAHVLDKLELPNETALVRYAVAHRIGDPL
HHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MIRLLMVDRHAVLRDGLRHILEKSGEFEIDGEAADAASAFELAGRGCAEIALLDQTTLGR
CEEEEEEHHHHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHCCCHHHEEECCHHHHHH
ECAELIRHLRRAAPSTRILVLAARASQRHAAAAFQAGASGYLTKQSGCEELLAALRKIAA
HHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHC
GGVYVSMHVAEQFAENLHSPSDAPPHERLSRREFEVFRRLAAGDTPADIAQALGISAKTV
CCCEEHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHH
RIYKAHVLDKLELPNETALVRYAVAHRIGDPL
HHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]