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The map label for this gene is dhbF [H]

Identifier: 126445099

GI number: 126445099

Start: 1736998

End: 1740246

Strand: Reverse

Name: dhbF [H]

Synonym: BURPS668_A1791

Alternate gene names: 126445099

Gene position: 1740246-1736998 (Counterclockwise)

Preceding gene: 126444331

Following gene: 126445431

Centisome position: 55.64

GC content: 72.79

Gene sequence:

>3249_bases
ATGCAGCATATCGACACAGGACTTCGCCTCGCCATGAACATGCGCGATACATCGCTTCGCCCGCTGCTGCCCGCCCAGCG
GGAGATCTGGCTCGCCGAGCAGTTGCGCCCGGGCACGGGTGTCTACAACACGGCGGGCTACGCCGACATCGTCGGCGCCG
TCGATCACGGCGCGCTGCGGGACGCGTTCGGCCACGCGATGCGCGAGGCCGACGCCGTGCGCGCGACGTTCTCCGCGCAC
GGTGACGACGCGTGGCAGACGCCGCGCGATGCGCCGCACGCCGACGTGCCGCTCGTCGACGTGAGCGGCCAGGCCGATCC
CGCCGGCGTCGCGCTCGGGTGGATGATGCGCGACATGCGCACGCCGCCCGATTTCGCGGCGGGCCCGCTGGTACGCAGCG
CGCTCTTGCGGGTGGGGGCGGCGCGCTTTTTCTGGTACGTCTGCGCGCATCACATCGTCACCGACGCGTACGGCACGGCG
CTCGTCGTGCAACGCACGGCGCAGCTCTACGGCGCGCGGGTGCGCGGCGCGGCGCCGCCGCCCGCGTGGTTCGGCACGCT
GGACGCGCTCATCGACGAGGACCGCGCGTATCGCGAATCGGCCGCGTTCGCCGACGATCGCGATTACTGGCGCGCCCGCC
TGGCGGCGGCGCCGGAGCCGCGCAGCCTGTCGCCCGTCGCGCTGCCGGGGCAGTTCGCGCCGGCCGGCGACTTTCACCGG
CAATGGGGCGAGCTCGACGCCGCGACGAGCGACGGGCTGCGCGCGATGGCGCGCGCCGGCGCACAAGGCATGCCGCCGCT
CGTCGCGGCGATGATGGCCGCCTATGTGCATCGGTTCACGCACGAGCGCGACGTCGTGCTCGGCTTGCCCGTCATGGCGC
GGCTAAGCCGCGCCACGCGCAGGACGCCGGGCATGGTCGCGAACGTGCTGCCGCTGCGCTTCGCGTTCGATCGCGGGACG
ACGTTCGCGGCGCTCCACGCGCAATGCGCGGCCGAGATGCGCGCGTCGCTGCGGCACCAGCGCTATCGCGGCGAGGCGAT
GCTGCGCGACGCGCAGCAGAGCCGGCCGGCCGAGCGCCTTCACGCGCAGAACGTGAACGTGATGGCGTTCGAGCGGGCGC
TCGCGTTCGGCGATTGCCCGGCGCGCTCGCACAGCCTGTCGAACGGCCCCGTCGACGATTTTTCGATCACCGTCTACGAC
GACGGCGCGAGGCAACCGATCCGCATCGCGTTCGACGCGAACGCGGCGCGCTATGCAAGCGGCGATCTGGCCGCGCATCG
CGAGCGCTTTCTGCGCCTTGGCGTCGCGCTCGCGAACGCGGCGCAGCGGCCGATCGCCGACGCGCAGTGGCTCACGCCCG
CCGAGCGCCGGACGCTGGTCGGCGAACGCGGCACGCCCGCGCCGGATGCGGGCGAGCCCTTCGACACCATCGCCGCGCGC
TTCGCGGCGCGGGCCGCCGAGCGCCCGGACGCGATCGCGCTCGTCGATCGCGGGCAGCGGATCACATACGGCGAGCTGAA
CGCGCGCGCGAATCGGCTCGCGCACGTGCTGATCGAGGCGGGCGTCGGGCCGGAGGCGCTGGTCGGCCTGCACATGCCGC
GCTCGGCCGAGCTCGTCGTCGGCATGCTCGCGATATTGAAGGCGGGCGGCGCGTACGTGCCGCTCGACCCCGCCTATCCG
GCCTCGCGCATCGAATTCATGGTGGCCGACGCGCGGCCGATGCTGTCGATCACGACGGGCGAGCACGCGGCGCAACTGCC
GGCCCGCACGCCGACGATCGTGCTCGACGCCGCCGACGCGCAGGCGGCGTTGCGGCGCGCGCCCGCGCACGACCCGGTGC
GGCCGGCGCCGCTCGATCGCGAGCACGCGGCGTACGTGATCTATACGTCCGGCTCCACCGGCAAGCCGAAGGGCGCGGTG
GTGTCGCATCGCAACGTGATCCGCCTGCTGGACGGCACGCGCGGCTGGTTCGATTTCGGCGCGGCGCAGACGTGGACGCT
GTTCCATTCGTTCGCATTCGATTTCTCGGTGTGGGAGTGCTGGGGCGCGCTGCTCACGGGCGGGCGGCTCGTCGTCGTGC
CTTACGACGTGAGCCGCTCGCCCGCCGAGTTCCTGAAGCTGCTGGTCGACGAGCGCGTGACGGTGCTCAATCAGACGCCG
TCGGCGTTTCGCCAGCTGATGCAGGCCGACGAGGCGCACGCGGACTTGAGCGCGCGGCTCGCGCTGCGCTACGTGGTGTT
CGGCGGCGAGGCGCTCGACGCGCGCAGCCTCGCGCGCTGGTATGAGCGGCACGCGGACACCGCGCCCCGGCTCGTCAACA
TGTACGGCATCACCGAGACGACGGTCCACGTCAGCTATCTGGCGCTCAGCCGCGCGATCGCCGGGATGCCGGCGAACAGC
CTGATCGGCCGGCCGCTTCCCGACTTGCGCGTGTATGTGCTCGACGCCGCGCTGCGCCCCGTGCCGGCGGGCGTGCCGGG
CGAGATGTACGTCGCCGGCGCGGGGCTCGCGCGCGGCTATCTGCGCCGGCCGTCGCTCACCGCGCAGCGCTTCATCGCCG
ATCCGTTCGGGCCGCCGGGCACGCGCATGTACCGCACGGGCGACGTCGCGCGATGGCGGGCCGACGGCGGGCTCGATTTC
ATCGGGCGGGCCGACGAGCAGGTGAAAGTGCGCGGCTTTCGCGTGGAGCTCGGCGAAATCGCCGCGCGGCTCGCGTGCGA
TCCGTCGGTCGCGCAGGCGCAGGCCGTCGTGCGGCAGGACGGGCCTGCGCACGAGCGGCTCGTCGCGTACGTCGTGCCGC
GCGCCGGCGCGACGATCGACGTTTGCGCGCTGCGCGCGTCGCTCGCGGCCGAGATGCCGGAATACATGGTGCCCGCGGCC
ATCGTCGCGCTCGATGCGATGCCGCTCACGCCGAACGGCAAACTCGACCGCGCGGCGCTGCCGGCGCCGATCGTGACGGG
CACGAGCCGGCGCGCGCCGGAAAACCGCATCGAGCAGCAGGTGTGCGCGATGTTCGCGGAACTGCTCGATGCGCAGACGC
TCGGCGCCGAGGACAATTTTTTCGAGCTCGGCGGCGATTCGCTGCTGGCGATGCGCGCGATCAACAAGCTGCAGCAGACG
TTCGATGTCGAGCTGACGATCCGCGATCTGTTTTCCGCGCCGACTGTCGCGGCGCTCAGCATGCGGCTCGATGCGCAATT
GGCGGCGCGCCGCGCTCACGCGGACGGCGCTGAGCTGCCCGCCGGGTAG

Upstream 100 bases:

>100_bases
GAAGCCGAGTGGACCGATCTGCGCCCGCGCAGCGTCGCCGCCCGATGCGCGTGAGCGCCGCGCCGTTCGCCATTCCCGGG
TGCGCGCCGTCGCGGCCCGC

Downstream 100 bases:

>100_bases
GCGGCGCGCCGCGCCGGTCCTCCGGGGGCGAGGCGGCCGGAATGCGTCGGCGCGAACGCGCGGGCAGGCGGCGCGTCGCG
CGGAGCATCGGCTTTGCCGT

Product: non-ribosomal peptide synthase

Products: pyrophosphate; AMP; enterobactin; pyrophosphate; L-Seryl-AMP [C]

Alternate protein names: NA

Number of amino acids: Translated: 1082; Mature: 1082

Protein sequence:

>1082_residues
MQHIDTGLRLAMNMRDTSLRPLLPAQREIWLAEQLRPGTGVYNTAGYADIVGAVDHGALRDAFGHAMREADAVRATFSAH
GDDAWQTPRDAPHADVPLVDVSGQADPAGVALGWMMRDMRTPPDFAAGPLVRSALLRVGAARFFWYVCAHHIVTDAYGTA
LVVQRTAQLYGARVRGAAPPPAWFGTLDALIDEDRAYRESAAFADDRDYWRARLAAAPEPRSLSPVALPGQFAPAGDFHR
QWGELDAATSDGLRAMARAGAQGMPPLVAAMMAAYVHRFTHERDVVLGLPVMARLSRATRRTPGMVANVLPLRFAFDRGT
TFAALHAQCAAEMRASLRHQRYRGEAMLRDAQQSRPAERLHAQNVNVMAFERALAFGDCPARSHSLSNGPVDDFSITVYD
DGARQPIRIAFDANAARYASGDLAAHRERFLRLGVALANAAQRPIADAQWLTPAERRTLVGERGTPAPDAGEPFDTIAAR
FAARAAERPDAIALVDRGQRITYGELNARANRLAHVLIEAGVGPEALVGLHMPRSAELVVGMLAILKAGGAYVPLDPAYP
ASRIEFMVADARPMLSITTGEHAAQLPARTPTIVLDAADAQAALRRAPAHDPVRPAPLDREHAAYVIYTSGSTGKPKGAV
VSHRNVIRLLDGTRGWFDFGAAQTWTLFHSFAFDFSVWECWGALLTGGRLVVVPYDVSRSPAEFLKLLVDERVTVLNQTP
SAFRQLMQADEAHADLSARLALRYVVFGGEALDARSLARWYERHADTAPRLVNMYGITETTVHVSYLALSRAIAGMPANS
LIGRPLPDLRVYVLDAALRPVPAGVPGEMYVAGAGLARGYLRRPSLTAQRFIADPFGPPGTRMYRTGDVARWRADGGLDF
IGRADEQVKVRGFRVELGEIAARLACDPSVAQAQAVVRQDGPAHERLVAYVVPRAGATIDVCALRASLAAEMPEYMVPAA
IVALDAMPLTPNGKLDRAALPAPIVTGTSRRAPENRIEQQVCAMFAELLDAQTLGAEDNFFELGGDSLLAMRAINKLQQT
FDVELTIRDLFSAPTVAALSMRLDAQLAARRAHADGAELPAG

Sequences:

>Translated_1082_residues
MQHIDTGLRLAMNMRDTSLRPLLPAQREIWLAEQLRPGTGVYNTAGYADIVGAVDHGALRDAFGHAMREADAVRATFSAH
GDDAWQTPRDAPHADVPLVDVSGQADPAGVALGWMMRDMRTPPDFAAGPLVRSALLRVGAARFFWYVCAHHIVTDAYGTA
LVVQRTAQLYGARVRGAAPPPAWFGTLDALIDEDRAYRESAAFADDRDYWRARLAAAPEPRSLSPVALPGQFAPAGDFHR
QWGELDAATSDGLRAMARAGAQGMPPLVAAMMAAYVHRFTHERDVVLGLPVMARLSRATRRTPGMVANVLPLRFAFDRGT
TFAALHAQCAAEMRASLRHQRYRGEAMLRDAQQSRPAERLHAQNVNVMAFERALAFGDCPARSHSLSNGPVDDFSITVYD
DGARQPIRIAFDANAARYASGDLAAHRERFLRLGVALANAAQRPIADAQWLTPAERRTLVGERGTPAPDAGEPFDTIAAR
FAARAAERPDAIALVDRGQRITYGELNARANRLAHVLIEAGVGPEALVGLHMPRSAELVVGMLAILKAGGAYVPLDPAYP
ASRIEFMVADARPMLSITTGEHAAQLPARTPTIVLDAADAQAALRRAPAHDPVRPAPLDREHAAYVIYTSGSTGKPKGAV
VSHRNVIRLLDGTRGWFDFGAAQTWTLFHSFAFDFSVWECWGALLTGGRLVVVPYDVSRSPAEFLKLLVDERVTVLNQTP
SAFRQLMQADEAHADLSARLALRYVVFGGEALDARSLARWYERHADTAPRLVNMYGITETTVHVSYLALSRAIAGMPANS
LIGRPLPDLRVYVLDAALRPVPAGVPGEMYVAGAGLARGYLRRPSLTAQRFIADPFGPPGTRMYRTGDVARWRADGGLDF
IGRADEQVKVRGFRVELGEIAARLACDPSVAQAQAVVRQDGPAHERLVAYVVPRAGATIDVCALRASLAAEMPEYMVPAA
IVALDAMPLTPNGKLDRAALPAPIVTGTSRRAPENRIEQQVCAMFAELLDAQTLGAEDNFFELGGDSLLAMRAINKLQQT
FDVELTIRDLFSAPTVAALSMRLDAQLAARRAHADGAELPAG
>Mature_1082_residues
MQHIDTGLRLAMNMRDTSLRPLLPAQREIWLAEQLRPGTGVYNTAGYADIVGAVDHGALRDAFGHAMREADAVRATFSAH
GDDAWQTPRDAPHADVPLVDVSGQADPAGVALGWMMRDMRTPPDFAAGPLVRSALLRVGAARFFWYVCAHHIVTDAYGTA
LVVQRTAQLYGARVRGAAPPPAWFGTLDALIDEDRAYRESAAFADDRDYWRARLAAAPEPRSLSPVALPGQFAPAGDFHR
QWGELDAATSDGLRAMARAGAQGMPPLVAAMMAAYVHRFTHERDVVLGLPVMARLSRATRRTPGMVANVLPLRFAFDRGT
TFAALHAQCAAEMRASLRHQRYRGEAMLRDAQQSRPAERLHAQNVNVMAFERALAFGDCPARSHSLSNGPVDDFSITVYD
DGARQPIRIAFDANAARYASGDLAAHRERFLRLGVALANAAQRPIADAQWLTPAERRTLVGERGTPAPDAGEPFDTIAAR
FAARAAERPDAIALVDRGQRITYGELNARANRLAHVLIEAGVGPEALVGLHMPRSAELVVGMLAILKAGGAYVPLDPAYP
ASRIEFMVADARPMLSITTGEHAAQLPARTPTIVLDAADAQAALRRAPAHDPVRPAPLDREHAAYVIYTSGSTGKPKGAV
VSHRNVIRLLDGTRGWFDFGAAQTWTLFHSFAFDFSVWECWGALLTGGRLVVVPYDVSRSPAEFLKLLVDERVTVLNQTP
SAFRQLMQADEAHADLSARLALRYVVFGGEALDARSLARWYERHADTAPRLVNMYGITETTVHVSYLALSRAIAGMPANS
LIGRPLPDLRVYVLDAALRPVPAGVPGEMYVAGAGLARGYLRRPSLTAQRFIADPFGPPGTRMYRTGDVARWRADGGLDF
IGRADEQVKVRGFRVELGEIAARLACDPSVAQAQAVVRQDGPAHERLVAYVVPRAGATIDVCALRASLAAEMPEYMVPAA
IVALDAMPLTPNGKLDRAALPAPIVTGTSRRAPENRIEQQVCAMFAELLDAQTLGAEDNFFELGGDSLLAMRAINKLQQT
FDVELTIRDLFSAPTVAALSMRLDAQLAARRAHADGAELPAG

Specific function: Specifically adenylates threonine and glycine, and loads them onto their corresponding peptidyl carrier domains [H]

COG id: COG1020

COG function: function code Q; Non-ribosomal peptide synthetase modules and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 acyl carrier domain [H]

Homologues:

Organism=Homo sapiens, GI45580730, Length=434, Percent_Identity=26.4976958525346, Blast_Score=125, Evalue=2e-28,
Organism=Homo sapiens, GI187761345, Length=599, Percent_Identity=25.8764607679466, Blast_Score=120, Evalue=7e-27,
Organism=Homo sapiens, GI187761343, Length=599, Percent_Identity=25.8764607679466, Blast_Score=120, Evalue=7e-27,
Organism=Homo sapiens, GI13375727, Length=587, Percent_Identity=21.9761499148211, Blast_Score=93, Evalue=1e-18,
Organism=Homo sapiens, GI38505220, Length=522, Percent_Identity=25.6704980842912, Blast_Score=89, Evalue=2e-17,
Organism=Homo sapiens, GI42544132, Length=526, Percent_Identity=21.8631178707224, Blast_Score=87, Evalue=8e-17,
Organism=Homo sapiens, GI122937307, Length=534, Percent_Identity=23.0337078651685, Blast_Score=78, Evalue=5e-14,
Organism=Homo sapiens, GI157311624, Length=517, Percent_Identity=21.8568665377176, Blast_Score=73, Evalue=2e-12,
Organism=Homo sapiens, GI157311622, Length=517, Percent_Identity=21.8568665377176, Blast_Score=73, Evalue=2e-12,
Organism=Escherichia coli, GI1786801, Length=1068, Percent_Identity=34.2696629213483, Blast_Score=477, Evalue=1e-135,
Organism=Escherichia coli, GI1786810, Length=537, Percent_Identity=26.8156424581006, Blast_Score=107, Evalue=5e-24,
Organism=Escherichia coli, GI145693145, Length=543, Percent_Identity=23.9410681399632, Blast_Score=105, Evalue=1e-23,
Organism=Escherichia coli, GI1788107, Length=555, Percent_Identity=24.6846846846847, Blast_Score=101, Evalue=2e-22,
Organism=Escherichia coli, GI221142682, Length=514, Percent_Identity=24.5136186770428, Blast_Score=100, Evalue=8e-22,
Organism=Escherichia coli, GI1789201, Length=379, Percent_Identity=28.7598944591029, Blast_Score=93, Evalue=8e-20,
Organism=Escherichia coli, GI1790505, Length=536, Percent_Identity=22.5746268656716, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17556356, Length=528, Percent_Identity=25.9469696969697, Blast_Score=129, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI17550940, Length=450, Percent_Identity=24.2222222222222, Blast_Score=100, Evalue=7e-21,
Organism=Caenorhabditis elegans, GI17558820, Length=502, Percent_Identity=23.5059760956175, Blast_Score=99, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17560308, Length=363, Percent_Identity=25.6198347107438, Blast_Score=75, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17559526, Length=385, Percent_Identity=24.1558441558442, Blast_Score=72, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6319591, Length=900, Percent_Identity=23.6666666666667, Blast_Score=216, Evalue=2e-56,
Organism=Saccharomyces cerevisiae, GI6319264, Length=534, Percent_Identity=23.7827715355805, Blast_Score=91, Evalue=7e-19,
Organism=Drosophila melanogaster, GI24648676, Length=577, Percent_Identity=31.1958405545927, Blast_Score=234, Evalue=2e-61,
Organism=Drosophila melanogaster, GI24581924, Length=551, Percent_Identity=25.5898366606171, Blast_Score=120, Evalue=4e-27,
Organism=Drosophila melanogaster, GI24582852, Length=533, Percent_Identity=23.827392120075, Blast_Score=91, Evalue=4e-18,
Organism=Drosophila melanogaster, GI62472339, Length=592, Percent_Identity=23.4797297297297, Blast_Score=91, Evalue=6e-18,
Organism=Drosophila melanogaster, GI24667955, Length=568, Percent_Identity=23.4154929577465, Blast_Score=90, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24667959, Length=408, Percent_Identity=25.2450980392157, Blast_Score=80, Evalue=1e-14,
Organism=Drosophila melanogaster, GI18859661, Length=488, Percent_Identity=21.9262295081967, Blast_Score=77, Evalue=9e-14,
Organism=Drosophila melanogaster, GI24648260, Length=469, Percent_Identity=22.8144989339019, Blast_Score=75, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010071
- InterPro:   IPR009081
- InterPro:   IPR020845
- InterPro:   IPR000873
- InterPro:   IPR001242
- InterPro:   IPR006163
- InterPro:   IPR020806
- InterPro:   IPR001031 [H]

Pfam domain/function: PF00501 AMP-binding; PF00668 Condensation; PF00550 PP-binding; PF00975 Thioesterase [H]

EC number: 2.7.7.- [C]

Molecular weight: Translated: 117068; Mature: 117068

Theoretical pI: Translated: 7.61; Mature: 7.61

Prosite motif: PS00012 PHOSPHOPANTETHEINE ; PS50075 ACP_DOMAIN ; PS00455 AMP_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQHIDTGLRLAMNMRDTSLRPLLPAQREIWLAEQLRPGTGVYNTAGYADIVGAVDHGALR
CCCCCCCHHEEECCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCHHHH
DAFGHAMREADAVRATFSAHGDDAWQTPRDAPHADVPLVDVSGQADPAGVALGWMMRDMR
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCHHHHHHHHHHCC
TPPDFAAGPLVRSALLRVGAARFFWYVCAHHIVTDAYGTALVVQRTAQLYGARVRGAAPP
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCHHCCCCCCC
PAWFGTLDALIDEDRAYRESAAFADDRDYWRARLAAAPEPRSLSPVALPGQFAPAGDFHR
CHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCEECCCCCCCCCHHHH
QWGELDAATSDGLRAMARAGAQGMPPLVAAMMAAYVHRFTHERDVVLGLPVMARLSRATR
HHCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHC
RTPGMVANVLPLRFAFDRGTTFAALHAQCAAEMRASLRHQRYRGEAMLRDAQQSRPAERL
CCCCHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
HAQNVNVMAFERALAFGDCPARSHSLSNGPVDDFSITVYDDGARQPIRIAFDANAARYAS
HHCCCCEEEHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCEEEEEECCCCCCCC
GDLAAHRERFLRLGVALANAAQRPIADAQWLTPAERRTLVGERGTPAPDAGEPFDTIAAR
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCHHHHHHH
FAARAAERPDAIALVDRGQRITYGELNARANRLAHVLIEAGVGPEALVGLHMPRSAELVV
HHHHHCCCCCEEEEECCCCEEEEHHHHHHHHHHHHHHHHCCCCHHHHEEECCCCHHHHHH
GMLAILKAGGAYVPLDPAYPASRIEFMVADARPMLSITTGEHAAQLPARTPTIVLDAADA
HHHHHHHCCCCEECCCCCCCHHHEEEEEECCCCEEEEECCCHHHHCCCCCCEEEEECCHH
QAALRRAPAHDPVRPAPLDREHAAYVIYTSGSTGKPKGAVVSHRNVIRLLDGTRGWFDFG
HHHHHHCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCEECCCCEEEEECCCCCCHHCC
AAQTWTLFHSFAFDFSVWECWGALLTGGRLVVVPYDVSRSPAEFLKLLVDERVTVLNQTP
CCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCH
SAFRQLMQADEAHADLSARLALRYVVFGGEALDARSLARWYERHADTAPRLVNMYGITET
HHHHHHHHHHHHHCCHHHHHEEEEEEECCCHHHHHHHHHHHHHHCCCCCHHHHHCCCCHH
TVHVSYLALSRAIAGMPANSLIGRPLPDLRVYVLDAALRPVPAGVPGEMYVAGAGLARGY
HHHHHHHHHHHHHHCCCCHHHCCCCCCHHEEEEEHHHHCCCCCCCCCCEEEECCHHHHHH
LRRPSLTAQRFIADPFGPPGTRMYRTGDVARWRADGGLDFIGRADEQVKVRGFRVELGEI
HCCCCHHHHHHHCCCCCCCCCCEEECCCCEEEECCCCCCCCCCCCCEEEEEEEEEEHHHH
AARLACDPSVAQAQAVVRQDGPAHERLVAYVVPRAGATIDVCALRASLAAEMPEYMVPAA
HHHHCCCCHHHHHHHHHHCCCCHHHEEEEEEECCCCCCHHHHHHHHHHHHHCHHHHHHHH
IVALDAMPLTPNGKLDRAALPAPIVTGTSRRAPENRIEQQVCAMFAELLDAQTLGAEDNF
HHHHCCCCCCCCCCCCCCCCCCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCE
FELGGDSLLAMRAINKLQQTFDVELTIRDLFSAPTVAALSMRLDAQLAARRAHADGAELP
EECCCCHHHHHHHHHHHHHHHCCEEEHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCC
AG
CC
>Mature Secondary Structure
MQHIDTGLRLAMNMRDTSLRPLLPAQREIWLAEQLRPGTGVYNTAGYADIVGAVDHGALR
CCCCCCCHHEEECCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCHHHH
DAFGHAMREADAVRATFSAHGDDAWQTPRDAPHADVPLVDVSGQADPAGVALGWMMRDMR
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCHHHHHHHHHHCC
TPPDFAAGPLVRSALLRVGAARFFWYVCAHHIVTDAYGTALVVQRTAQLYGARVRGAAPP
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCHHCCCCCCC
PAWFGTLDALIDEDRAYRESAAFADDRDYWRARLAAAPEPRSLSPVALPGQFAPAGDFHR
CHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCEECCCCCCCCCHHHH
QWGELDAATSDGLRAMARAGAQGMPPLVAAMMAAYVHRFTHERDVVLGLPVMARLSRATR
HHCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHC
RTPGMVANVLPLRFAFDRGTTFAALHAQCAAEMRASLRHQRYRGEAMLRDAQQSRPAERL
CCCCHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
HAQNVNVMAFERALAFGDCPARSHSLSNGPVDDFSITVYDDGARQPIRIAFDANAARYAS
HHCCCCEEEHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCEEEEEECCCCCCCC
GDLAAHRERFLRLGVALANAAQRPIADAQWLTPAERRTLVGERGTPAPDAGEPFDTIAAR
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCHHHHHHH
FAARAAERPDAIALVDRGQRITYGELNARANRLAHVLIEAGVGPEALVGLHMPRSAELVV
HHHHHCCCCCEEEEECCCCEEEEHHHHHHHHHHHHHHHHCCCCHHHHEEECCCCHHHHHH
GMLAILKAGGAYVPLDPAYPASRIEFMVADARPMLSITTGEHAAQLPARTPTIVLDAADA
HHHHHHHCCCCEECCCCCCCHHHEEEEEECCCCEEEEECCCHHHHCCCCCCEEEEECCHH
QAALRRAPAHDPVRPAPLDREHAAYVIYTSGSTGKPKGAVVSHRNVIRLLDGTRGWFDFG
HHHHHHCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCEECCCCEEEEECCCCCCHHCC
AAQTWTLFHSFAFDFSVWECWGALLTGGRLVVVPYDVSRSPAEFLKLLVDERVTVLNQTP
CCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCH
SAFRQLMQADEAHADLSARLALRYVVFGGEALDARSLARWYERHADTAPRLVNMYGITET
HHHHHHHHHHHHHCCHHHHHEEEEEEECCCHHHHHHHHHHHHHHCCCCCHHHHHCCCCHH
TVHVSYLALSRAIAGMPANSLIGRPLPDLRVYVLDAALRPVPAGVPGEMYVAGAGLARGY
HHHHHHHHHHHHHHCCCCHHHCCCCCCHHEEEEEHHHHCCCCCCCCCCEEEECCHHHHHH
LRRPSLTAQRFIADPFGPPGTRMYRTGDVARWRADGGLDFIGRADEQVKVRGFRVELGEI
HCCCCHHHHHHHCCCCCCCCCCEEECCCCEEEECCCCCCCCCCCCCEEEEEEEEEEHHHH
AARLACDPSVAQAQAVVRQDGPAHERLVAYVVPRAGATIDVCALRASLAAEMPEYMVPAA
HHHHCCCCHHHHHHHHHHCCCCHHHEEEEEEECCCCCCHHHHHHHHHHHHHCHHHHHHHH
IVALDAMPLTPNGKLDRAALPAPIVTGTSRRAPENRIEQQVCAMFAELLDAQTLGAEDNF
HHHHCCCCCCCCCCCCCCCCCCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCE
FELGGDSLLAMRAINKLQQTFDVELTIRDLFSAPTVAALSMRLDAQLAARRAHADGAELP
EECCCCHHHHHHHHHHHHHHHCCEEEHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCC
AG
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Phosphopantetheine. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 6 ATP; L-serine; 2,3-dihydroxybenzoate [C]

Specific reaction: 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Seryl-AMP 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Ser

General reaction: Transferases; Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11112781; 9384377; 10568751; 8550523 [H]