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The map label for this gene is frc [H]

Identifier: 126445052

GI number: 126445052

Start: 1722325

End: 1723743

Strand: Reverse

Name: frc [H]

Synonym: BURPS668_A1776

Alternate gene names: 126445052

Gene position: 1723743-1722325 (Counterclockwise)

Preceding gene: 126442879

Following gene: 126444710

Centisome position: 55.12

GC content: 75.48

Gene sequence:

>1419_bases
ATGTTCGATCTCGCTGCTTCATCCCACACGGAGCCGTCCGGCCATGCGCGTGCCGCCGCGTATCTGCGCGACATCTGGCA
GGCCGCGAACGGCGATCCCGAGTGGCTGCGCACGCTGGCATTCGGCGGCGCGGGCGTGTTGCCGTCGGCCTTTCCGGTCA
CCGATTTCGCCTCGGCCGCGATCGGCGCGGCGAGCGTCGCGCTCGCCGAGTTCGTGCATCGCGCGACGGGCCGGCTGCCC
GGCGTGCGCGTCGATCGCCGCTACGCATCGCTCTGGTTCGGCACGTCGCTGCGTCCGCGCGGCTGGAACATGCCGCCTCT
GTGGGATGCGATCGCGGGCGACTACCGCACGGCCGACGGCTGGATCCGGCTGCACACGAACGCGCCGCATCATCGCGCGG
CCGCGCTCGCCGTGCTCGGCGCGCCGCCCGAGCGGCAAGCCGTCGCCCGCGCGGTCGGGCAATGGCGCGGCGACGCGCTC
GAATCGGCGGTCGTCGAGCACGGCGGCTGCGCGGCCGTCATGCGCACGGAGGACGAATGGGCGCGCCATCCGCAAGGGCG
CGCGGTGCGCGCGGAGCCGCTGATGATTCACGACGACGTGAGTATCGACGGCCCGCGCCCCGCGTGGCCGATGTCGGCCG
AGCGGCCGCTGCGCGGCGTGCGCGTGCTCGATCTGACGCGCATCCTCGCGGGCCCCGTCGCGACGCGCTTTCTCGCGGGC
TTCGGCGCACAGGTGCTGCGCATCGATCCGATCGGCTGGGACGAGCCGGGCACGGTGCCCGAAGTCGTGCTCGGCAAGCG
GTGCGCGCGCGCCAACCTCGCCTGCGCCGACGGGCGCGCGCTGCTGCGCCGCCTGATCGGCGAGGCCGACGTGATGGTCC
ACGGCTACCGGCCGGGCGCGCTCGACCGTCTCGGCTTCGACGCCGACGAGCGGCGGCGGATCAACCCCGGCCTCGTCGAC
GTGTCGCTCGACGCGTATGGCTGGAGCGGGCCCTGGCGCGGCCGCCGGGGCTTCGACAGCCTCGTGCAGACGAGCGCGGG
CATCGCGGCGGCCGGCATGCGCGAAGCCGGCGCCGACCGCCCGGTGCCGCTGCCCGTTCAGGCGCTCGACCACGGCACCG
GCTATCTGCTCGCGGCCGCGGCGATTCGGGGCCTCGTGCGCCGGCTCGCGACGGGCGCCGGGACGAGCACGCGCGCGTCG
CTCGCGCGAACCGCGGTGCTGCTCACGTCGGGCGGCTTGCAGGAAGCGGGCCGCCAGCCGATCGCGCCGGAGACGGCGGG
CGATCTCGACGCGTGGATCGAGGACACGAGCTGGGGGCCGGCGCAGCGCGTGCGTGCGCCGGTGACGATCGAGTGCGCGC
CGGTGCAATGGCCGCATCCGGCGCGCGCGCTCGGCACGTCGCCCGCCGAGTGGGCGTAG

Upstream 100 bases:

>100_bases
CGGAAGTGAATAAAAATGACTTGATTCCCGGAATCAACGTTGACACTCGCGTTGCGCGGGAAATAATCTTGCCGCGCTAT
CTTCGAATCGGGGGCGTCAC

Downstream 100 bases:

>100_bases
CCGGTAGCGGGCGACGGCGGACGAGCGCATGCGAAAGCGGCCGGACGCGTTGCGGCCGCACCGGAGCGTGCCGTTCGGGC
TCGCGACCGAAACGGGCCCA

Product: CAIB/BAIF family CoA transferase

Products: NA

Alternate protein names: Formyl-CoA transferase [H]

Number of amino acids: Translated: 472; Mature: 472

Protein sequence:

>472_residues
MFDLAASSHTEPSGHARAAAYLRDIWQAANGDPEWLRTLAFGGAGVLPSAFPVTDFASAAIGAASVALAEFVHRATGRLP
GVRVDRRYASLWFGTSLRPRGWNMPPLWDAIAGDYRTADGWIRLHTNAPHHRAAALAVLGAPPERQAVARAVGQWRGDAL
ESAVVEHGGCAAVMRTEDEWARHPQGRAVRAEPLMIHDDVSIDGPRPAWPMSAERPLRGVRVLDLTRILAGPVATRFLAG
FGAQVLRIDPIGWDEPGTVPEVVLGKRCARANLACADGRALLRRLIGEADVMVHGYRPGALDRLGFDADERRRINPGLVD
VSLDAYGWSGPWRGRRGFDSLVQTSAGIAAAGMREAGADRPVPLPVQALDHGTGYLLAAAAIRGLVRRLATGAGTSTRAS
LARTAVLLTSGGLQEAGRQPIAPETAGDLDAWIEDTSWGPAQRVRAPVTIECAPVQWPHPARALGTSPAEWA

Sequences:

>Translated_472_residues
MFDLAASSHTEPSGHARAAAYLRDIWQAANGDPEWLRTLAFGGAGVLPSAFPVTDFASAAIGAASVALAEFVHRATGRLP
GVRVDRRYASLWFGTSLRPRGWNMPPLWDAIAGDYRTADGWIRLHTNAPHHRAAALAVLGAPPERQAVARAVGQWRGDAL
ESAVVEHGGCAAVMRTEDEWARHPQGRAVRAEPLMIHDDVSIDGPRPAWPMSAERPLRGVRVLDLTRILAGPVATRFLAG
FGAQVLRIDPIGWDEPGTVPEVVLGKRCARANLACADGRALLRRLIGEADVMVHGYRPGALDRLGFDADERRRINPGLVD
VSLDAYGWSGPWRGRRGFDSLVQTSAGIAAAGMREAGADRPVPLPVQALDHGTGYLLAAAAIRGLVRRLATGAGTSTRAS
LARTAVLLTSGGLQEAGRQPIAPETAGDLDAWIEDTSWGPAQRVRAPVTIECAPVQWPHPARALGTSPAEWA
>Mature_472_residues
MFDLAASSHTEPSGHARAAAYLRDIWQAANGDPEWLRTLAFGGAGVLPSAFPVTDFASAAIGAASVALAEFVHRATGRLP
GVRVDRRYASLWFGTSLRPRGWNMPPLWDAIAGDYRTADGWIRLHTNAPHHRAAALAVLGAPPERQAVARAVGQWRGDAL
ESAVVEHGGCAAVMRTEDEWARHPQGRAVRAEPLMIHDDVSIDGPRPAWPMSAERPLRGVRVLDLTRILAGPVATRFLAG
FGAQVLRIDPIGWDEPGTVPEVVLGKRCARANLACADGRALLRRLIGEADVMVHGYRPGALDRLGFDADERRRINPGLVD
VSLDAYGWSGPWRGRRGFDSLVQTSAGIAAAGMREAGADRPVPLPVQALDHGTGYLLAAAAIRGLVRRLATGAGTSTRAS
LARTAVLLTSGGLQEAGRQPIAPETAGDLDAWIEDTSWGPAQRVRAPVTIECAPVQWPHPARALGTSPAEWA

Specific function: Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate [H]

COG id: COG1804

COG function: function code C; Predicted acyl-CoA transferases/carnitine dehydratase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CaiB/BaiF CoA-transferase family [H]

Homologues:

Organism=Homo sapiens, GI300863124, Length=214, Percent_Identity=29.9065420560748, Blast_Score=99, Evalue=7e-21,
Organism=Homo sapiens, GI300863128, Length=218, Percent_Identity=29.8165137614679, Blast_Score=99, Evalue=7e-21,
Organism=Homo sapiens, GI300863126, Length=208, Percent_Identity=29.3269230769231, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI266456254, Length=197, Percent_Identity=30.4568527918782, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI42794625, Length=197, Percent_Identity=30.4568527918782, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI266458393, Length=197, Percent_Identity=29.9492385786802, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI266458397, Length=197, Percent_Identity=29.9492385786802, Blast_Score=74, Evalue=4e-13,
Organism=Escherichia coli, GI1788717, Length=217, Percent_Identity=28.110599078341, Blast_Score=89, Evalue=8e-19,
Organism=Escherichia coli, GI87082093, Length=251, Percent_Identity=24.7011952191235, Blast_Score=86, Evalue=6e-18,
Organism=Drosophila melanogaster, GI24648431, Length=192, Percent_Identity=33.8541666666667, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24585488, Length=197, Percent_Identity=28.9340101522843, Blast_Score=75, Evalue=9e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003673
- InterPro:   IPR017659 [H]

Pfam domain/function: PF02515 CoA_transf_3 [H]

EC number: =2.8.3.16 [H]

Molecular weight: Translated: 50342; Mature: 50342

Theoretical pI: Translated: 8.65; Mature: 8.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFDLAASSHTEPSGHARAAAYLRDIWQAANGDPEWLRTLAFGGAGVLPSAFPVTDFASAA
CCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHH
IGAASVALAEFVHRATGRLPGVRVDRRYASLWFGTSLRPRGWNMPPLWDAIAGDYRTADG
HHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHEECCCCCCCCCCCCCHHHHHCCCCEECCC
WIRLHTNAPHHRAAALAVLGAPPERQAVARAVGQWRGDALESAVVEHGGCAAVMRTEDEW
EEEEECCCCCHHHHEEEEECCCCHHHHHHHHHHHHCHHHHHHHHHHCCCEEEEEECCHHH
ARHPQGRAVRAEPLMIHDDVSIDGPRPAWPMSAERPLRGVRVLDLTRILAGPVATRFLAG
HHCCCCCCEECCCEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
FGAQVLRIDPIGWDEPGTVPEVVLGKRCARANLACADGRALLRRLIGEADVMVHGYRPGA
CCCEEEEECCCCCCCCCCCHHHHHHHHHHHCCCEECCHHHHHHHHHCCCCEEEECCCCCC
LDRLGFDADERRRINPGLVDVSLDAYGWSGPWRGRRGFDSLVQTSAGIAAAGMREAGADR
HHHCCCCCHHCCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHCCHHHHCHHHCCCCC
PVPLPVQALDHGTGYLLAAAAIRGLVRRLATGAGTSTRASLARTAVLLTSGGLQEAGRQP
CCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHEEECCCHHHHCCCC
IAPETAGDLDAWIEDTSWGPAQRVRAPVTIECAPVQWPHPARALGTSPAEWA
CCCCCCCCHHHHHCCCCCCHHHHCCCCEEEEECCCCCCCCHHHHCCCCCCCC
>Mature Secondary Structure
MFDLAASSHTEPSGHARAAAYLRDIWQAANGDPEWLRTLAFGGAGVLPSAFPVTDFASAA
CCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHH
IGAASVALAEFVHRATGRLPGVRVDRRYASLWFGTSLRPRGWNMPPLWDAIAGDYRTADG
HHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHEECCCCCCCCCCCCCHHHHHCCCCEECCC
WIRLHTNAPHHRAAALAVLGAPPERQAVARAVGQWRGDALESAVVEHGGCAAVMRTEDEW
EEEEECCCCCHHHHEEEEECCCCHHHHHHHHHHHHCHHHHHHHHHHCCCEEEEEECCHHH
ARHPQGRAVRAEPLMIHDDVSIDGPRPAWPMSAERPLRGVRVLDLTRILAGPVATRFLAG
HHCCCCCCEECCCEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
FGAQVLRIDPIGWDEPGTVPEVVLGKRCARANLACADGRALLRRLIGEADVMVHGYRPGA
CCCEEEEECCCCCCCCCCCHHHHHHHHHHHCCCEECCHHHHHHHHHCCCCEEEECCCCCC
LDRLGFDADERRRINPGLVDVSLDAYGWSGPWRGRRGFDSLVQTSAGIAAAGMREAGADR
HHHCCCCCHHCCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHCCHHHHCHHHCCCCC
PVPLPVQALDHGTGYLLAAAAIRGLVRRLATGAGTSTRASLARTAVLLTSGGLQEAGRQP
CCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHEEECCCHHHHCCCC
IAPETAGDLDAWIEDTSWGPAQRVRAPVTIECAPVQWPHPARALGTSPAEWA
CCCCCCCCHHHHHCCCCCCHHHHCCCCEEEEECCCCCCCCHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA