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The map label for this gene is intZ [H]

Identifier: 126444968

GI number: 126444968

Start: 2310841

End: 2312088

Strand: Reverse

Name: intZ [H]

Synonym: BURPS668_A2389

Alternate gene names: 126444968

Gene position: 2312088-2310841 (Counterclockwise)

Preceding gene: 126443505

Following gene: 126445169

Centisome position: 73.93

GC content: 66.35

Gene sequence:

>1248_bases
ATGGCGTCGCGTCAGATGAATCGATTGACCGCGCTCGGCATCGGCAAGCTCGTTGATCCGGGATATTACGCTGACGGCGG
CGGCCTGTACTTGCAGATCAGCGCGAGCGGATCGCGGTCATGGATCTACCGCTTCTCGCTCGCCGGCCGCGCGCGGGAGA
TGGGCCTCGGCTCGCTGTCGGTGTTGCCGCTCGCCGCGGCGCGCAAGGTAGCGGCAGACTGCCGCGCGAGCGTGAAGCAT
GGCATCGATCCGATCGCTGCGCGGCGGCGCGCGCAGGTTATGCGAGCCGCCGAGGGAGCGCCCGGCGTGACGTTCAGGCA
GGCGGCCGAGGCATTCATCGCCGATCGCGCGTCGGGCTGGCGCAACACGAAACATGCGAAGCAGTGGACATCCACCCTGG
AAGCCTACGCCTATCCCGTGATCGGCGATATCGACGTGCGCGACATCGACACGGAAATGATCGTGCGCATCCTGCAGCCG
ATCTGGATGAAGAAGGGCGAGACGGCGCGGCGCGTGCGCGGGCGCGTGAAAGCGATCCTCGATGCCGAGACAGTGCTCGG
CCACCGGACAGGCGACAACCCGGCGCGCTACGTCGACCACCTCGATCGCGTGCTGCCGCGGGTGAAGAAGCGCAACAGCG
TGAAGCATCACCCGGCGCTGTCGTGGGAGGAGATGCCCGCGTTTTTCGCGGCGCTGCGCCAGCGCCCCAAGCGCGCCGCG
CAGGCGCTGCGTCTGCTGATCCTCACGGCGACGCGCACGAATGAAGTATTGTTCGCGCGGCCTGAGGAGTTCGACCTCGA
TGCGCGCGTCTGGACAATTCCGGGTGACCGGATGAAAGCAGAGCAGGAGCTGCGCGTGCCCCTGTGCGACGAAGCCGTCG
AGCTCGTGCGCATGCAGATCGCGACAAAGGCAAAGTGGGGATGGCTGTTTCCGGGGTACAAGGAGGGGCGCCCGCTGTCG
AATATGGCTATGCTCCTGTTGCTGCGCCGCATGGACCGCAGCGACATCACAGTGCACGGGTTCCGTTCGACGTTCCGGGA
TTGGATTGCGGACTGCACAGACTATCCCGATTCACTCGCCGAGCAGGCGCTCGCGCACACGATCTCGTCGACGACCGTTT
CCGCATACCGGCGCCGAGATATGCTCGAGCGCCGGCGCGGGATGATGGAGGACTGGGCGCGGTACTGCGCGGGGCAGACC
GCGACCGTTGTGCCGTTCACGCACCCTGCTGCGCACACAGCTGCGTAA

Upstream 100 bases:

>100_bases
CCTTATCCAGCGTGTGTTTTGGGGGTGTCGTTGCTCTTGCTGGCTCCCAAGCGCTGCCCCAAAATCTAACTATTATTTGT
GGGTAGGATTGGGGGTAGAT

Downstream 100 bases:

>100_bases
TGTTGTCGTCCGGCCTTTCAGCGGCCGGCTTCTTCCCGGCTTTCTCTGCCAGCCACGCGTCGATGTCCTCCTCAAGCCAC
GCCGTGCGGCCTGGTACGAG

Product: integrase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 415; Mature: 414

Protein sequence:

>415_residues
MASRQMNRLTALGIGKLVDPGYYADGGGLYLQISASGSRSWIYRFSLAGRAREMGLGSLSVLPLAAARKVAADCRASVKH
GIDPIAARRRAQVMRAAEGAPGVTFRQAAEAFIADRASGWRNTKHAKQWTSTLEAYAYPVIGDIDVRDIDTEMIVRILQP
IWMKKGETARRVRGRVKAILDAETVLGHRTGDNPARYVDHLDRVLPRVKKRNSVKHHPALSWEEMPAFFAALRQRPKRAA
QALRLLILTATRTNEVLFARPEEFDLDARVWTIPGDRMKAEQELRVPLCDEAVELVRMQIATKAKWGWLFPGYKEGRPLS
NMAMLLLLRRMDRSDITVHGFRSTFRDWIADCTDYPDSLAEQALAHTISSTTVSAYRRRDMLERRRGMMEDWARYCAGQT
ATVVPFTHPAAHTAA

Sequences:

>Translated_415_residues
MASRQMNRLTALGIGKLVDPGYYADGGGLYLQISASGSRSWIYRFSLAGRAREMGLGSLSVLPLAAARKVAADCRASVKH
GIDPIAARRRAQVMRAAEGAPGVTFRQAAEAFIADRASGWRNTKHAKQWTSTLEAYAYPVIGDIDVRDIDTEMIVRILQP
IWMKKGETARRVRGRVKAILDAETVLGHRTGDNPARYVDHLDRVLPRVKKRNSVKHHPALSWEEMPAFFAALRQRPKRAA
QALRLLILTATRTNEVLFARPEEFDLDARVWTIPGDRMKAEQELRVPLCDEAVELVRMQIATKAKWGWLFPGYKEGRPLS
NMAMLLLLRRMDRSDITVHGFRSTFRDWIADCTDYPDSLAEQALAHTISSTTVSAYRRRDMLERRRGMMEDWARYCAGQT
ATVVPFTHPAAHTAA
>Mature_414_residues
ASRQMNRLTALGIGKLVDPGYYADGGGLYLQISASGSRSWIYRFSLAGRAREMGLGSLSVLPLAAARKVAADCRASVKHG
IDPIAARRRAQVMRAAEGAPGVTFRQAAEAFIADRASGWRNTKHAKQWTSTLEAYAYPVIGDIDVRDIDTEMIVRILQPI
WMKKGETARRVRGRVKAILDAETVLGHRTGDNPARYVDHLDRVLPRVKKRNSVKHHPALSWEEMPAFFAALRQRPKRAAQ
ALRLLILTATRTNEVLFARPEEFDLDARVWTIPGDRMKAEQELRVPLCDEAVELVRMQIATKAKWGWLFPGYKEGRPLSN
MAMLLLLRRMDRSDITVHGFRSTFRDWIADCTDYPDSLAEQALAHTISSTTVSAYRRRDMLERRRGMMEDWARYCAGQTA
TVVPFTHPAAHTAA

Specific function: Integrase is necessary for integration of the phage into the host genome by site-specific recombination. In conjunction with excisionase, integrase is also necessary for excision of the prophage from the host genome [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family [H]

Homologues:

Organism=Escherichia coli, GI145693166, Length=368, Percent_Identity=33.1521739130435, Blast_Score=162, Evalue=4e-41,
Organism=Escherichia coli, GI1788974, Length=404, Percent_Identity=27.7227722772277, Blast_Score=132, Evalue=5e-32,
Organism=Escherichia coli, GI1788690, Length=375, Percent_Identity=25.6, Blast_Score=112, Evalue=4e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR023109 [H]

Pfam domain/function: PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 46682; Mature: 46551

Theoretical pI: Translated: 10.59; Mature: 10.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASRQMNRLTALGIGKLVDPGYYADGGGLYLQISASGSRSWIYRFSLAGRAREMGLGSLS
CCCCHHHHHHHHHHHHHCCCCEEECCCCEEEEEECCCCCCEEEEEEECCHHHHCCCCCHH
VLPLAAARKVAADCRASVKHGIDPIAARRRAQVMRAAEGAPGVTFRQAAEAFIADRASGW
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCC
RNTKHAKQWTSTLEAYAYPVIGDIDVRDIDTEMIVRILQPIWMKKGETARRVRGRVKAIL
CCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
DAETVLGHRTGDNPARYVDHLDRVLPRVKKRNSVKHHPALSWEEMPAFFAALRQRPKRAA
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
QALRLLILTATRTNEVLFARPEEFDLDARVWTIPGDRMKAEQELRVPLCDEAVELVRMQI
HHHHHHHHEECCCCCEEEECCCCCCCCCEEEECCCHHHCCHHHCCCCCHHHHHHHHHHHH
ATKAKWGWLFPGYKEGRPLSNMAMLLLLRRMDRSDITVHGFRSTFRDWIADCTDYPDSLA
HHCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHCCCHHHHH
EQALAHTISSTTVSAYRRRDMLERRRGMMEDWARYCAGQTATVVPFTHPAAHTAA
HHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCEEEEECCCCCCCCCC
>Mature Secondary Structure 
ASRQMNRLTALGIGKLVDPGYYADGGGLYLQISASGSRSWIYRFSLAGRAREMGLGSLS
CCCHHHHHHHHHHHHHCCCCEEECCCCEEEEEECCCCCCEEEEEEECCHHHHCCCCCHH
VLPLAAARKVAADCRASVKHGIDPIAARRRAQVMRAAEGAPGVTFRQAAEAFIADRASGW
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCC
RNTKHAKQWTSTLEAYAYPVIGDIDVRDIDTEMIVRILQPIWMKKGETARRVRGRVKAIL
CCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
DAETVLGHRTGDNPARYVDHLDRVLPRVKKRNSVKHHPALSWEEMPAFFAALRQRPKRAA
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
QALRLLILTATRTNEVLFARPEEFDLDARVWTIPGDRMKAEQELRVPLCDEAVELVRMQI
HHHHHHHHEECCCCCEEEECCCCCCCCCEEEECCCHHHCCHHHCCCCCHHHHHHHHHHHH
ATKAKWGWLFPGYKEGRPLSNMAMLLLLRRMDRSDITVHGFRSTFRDWIADCTDYPDSLA
HHCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHCCCHHHHH
EQALAHTISSTTVSAYRRRDMLERRRGMMEDWARYCAGQTATVVPFTHPAAHTAA
HHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]