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The map label for this gene is phnW [H]

Identifier: 126444912

GI number: 126444912

Start: 746708

End: 747775

Strand: Reverse

Name: phnW [H]

Synonym: BURPS668_A0778

Alternate gene names: 126444912

Gene position: 747775-746708 (Counterclockwise)

Preceding gene: 126442994

Following gene: 126444847

Centisome position: 23.91

GC content: 71.72

Gene sequence:

>1068_bases
ATGCTGTTGCTGAATCCCGGTCCCGTGACGCTGACGGAGCGTGTGCGCCAAAGCCTGCTGCAGCCGGACCTGTGCCACCG
CGAAAGCGAATTCTTCGATCTGCAGGACGAGGCGCGCGCGCGGCTCGTCGCCGCGTACGCGCTCGATCCGGCCGAATGGA
GCGCGGTGCTGATGACGGGCTCCGGCACGGCCGCGGTCGAGAGCATGATCGCCGCGCTCGTGCCGGAAAACGGCAAGCTG
CTCGTGATCGAGAACGGCGTGTACGGCGAGCGGATCACGCAGATCGCGACGCAGTACCGGATCGCGCACGACGTGCTGAA
GCACGACTGGATGCAGGCGCCGGATCTCGCGCGCGTCGCCGAGAAGCTCGACGCGGATCGCGCGATCACGCATGTCGCGG
TGATCCATCACGAAACGACCACGGGCCGCCTGAACGACCTCGACGCGCTCGCCGCCGTGTGCCGCGCGCGCGGCGTGCGC
ATGCTCGTCGACGGCGTGAGCAGCTTCGGCGCGGAGGCGATCGATTTCGCGGGCGGCGACATCGACGCGCTCGCCGCGAC
CGCGAACAAGTGCCTGCACGGCGTGCCGGGCGCGGCGTTCGTGATCGTGCGCCGCCGCGCGCTCGCGAGTGCCGCGAGCC
GCACCTACTACCTCGATCTCGGCCGGCTCGCGAAGCTGCAGGACGCGCGCAACACGCCGTTCACGCCGTCGGTGCACGCG
TACTACGCGCTCGTCGAGGCGCTGCGCGAGTTCGACGAGGCGGGCGGCTGGCGCGCGCGCCACGCGCGCTACGCGGCGCT
CGCCGAACAGGTGCGCGCCGGCCTCGCCGCGCGCGGCATGCCGCTCGTGCTGCCGGACGGCGAATCGTCGGTCGTGCTGC
GCGCGTACCGGCTGCCCGCCGGCGTCGCGTACGAGCAACTGCACGACGGCCTGAAAGCGCGCGGCTTCGTGATCTACGCG
GGCCAGGGCGGGCTGTCGAGCGCGTTGTTCCGCGTGTCGACGATGGGCGCGATCGAGCCCGCGGACGTCGAGCGCCTCCT
CGACGGATTCACCGCGCTCGCGCGCTGA

Upstream 100 bases:

>100_bases
TGCCCGACGGCCTGCCCCGCCCGACGGTGACGCCCGTCGACGTGAAAACGCGCCTGATGCGCCACATCGGCGCGATGCCG
GCCTGACAAGGAGTACGAAG

Downstream 100 bases:

>100_bases
TCCCGCCCGGCGGCGTCGCGCTCGAATCGCGCGGCGCCGCTTTCCCGGGCCCACGCCCCGCTTTGCTCCCCGCGAAAACG
CGCCGCCGCGCGGGCCGCCC

Product: 2-aminoethylphosphonate-pyruvate transaminase

Products: NA

Alternate protein names: 2-aminoethylphosphonate aminotransferase; AEP transaminase; AEPT [H]

Number of amino acids: Translated: 355; Mature: 355

Protein sequence:

>355_residues
MLLLNPGPVTLTERVRQSLLQPDLCHRESEFFDLQDEARARLVAAYALDPAEWSAVLMTGSGTAAVESMIAALVPENGKL
LVIENGVYGERITQIATQYRIAHDVLKHDWMQAPDLARVAEKLDADRAITHVAVIHHETTTGRLNDLDALAAVCRARGVR
MLVDGVSSFGAEAIDFAGGDIDALAATANKCLHGVPGAAFVIVRRRALASAASRTYYLDLGRLAKLQDARNTPFTPSVHA
YYALVEALREFDEAGGWRARHARYAALAEQVRAGLAARGMPLVLPDGESSVVLRAYRLPAGVAYEQLHDGLKARGFVIYA
GQGGLSSALFRVSTMGAIEPADVERLLDGFTALAR

Sequences:

>Translated_355_residues
MLLLNPGPVTLTERVRQSLLQPDLCHRESEFFDLQDEARARLVAAYALDPAEWSAVLMTGSGTAAVESMIAALVPENGKL
LVIENGVYGERITQIATQYRIAHDVLKHDWMQAPDLARVAEKLDADRAITHVAVIHHETTTGRLNDLDALAAVCRARGVR
MLVDGVSSFGAEAIDFAGGDIDALAATANKCLHGVPGAAFVIVRRRALASAASRTYYLDLGRLAKLQDARNTPFTPSVHA
YYALVEALREFDEAGGWRARHARYAALAEQVRAGLAARGMPLVLPDGESSVVLRAYRLPAGVAYEQLHDGLKARGFVIYA
GQGGLSSALFRVSTMGAIEPADVERLLDGFTALAR
>Mature_355_residues
MLLLNPGPVTLTERVRQSLLQPDLCHRESEFFDLQDEARARLVAAYALDPAEWSAVLMTGSGTAAVESMIAALVPENGKL
LVIENGVYGERITQIATQYRIAHDVLKHDWMQAPDLARVAEKLDADRAITHVAVIHHETTTGRLNDLDALAAVCRARGVR
MLVDGVSSFGAEAIDFAGGDIDALAATANKCLHGVPGAAFVIVRRRALASAASRTYYLDLGRLAKLQDARNTPFTPSVHA
YYALVEALREFDEAGGWRARHARYAALAEQVRAGLAARGMPLVLPDGESSVVLRAYRLPAGVAYEQLHDGLKARGFVIYA
GQGGLSSALFRVSTMGAIEPADVERLLDGFTALAR

Specific function: Involved in phosphonate degradation [H]

COG id: COG0075

COG function: function code E; Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557289, Length=305, Percent_Identity=26.2295081967213, Blast_Score=84, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17536281, Length=346, Percent_Identity=24.2774566473988, Blast_Score=85, Evalue=6e-17,
Organism=Drosophila melanogaster, GI17530823, Length=356, Percent_Identity=22.4719101123595, Blast_Score=84, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017688
- InterPro:   IPR000192
- InterPro:   IPR012703
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.6.1.37 [H]

Molecular weight: Translated: 38281; Mature: 38281

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLLNPGPVTLTERVRQSLLQPDLCHRESEFFDLQDEARARLVAAYALDPAEWSAVLMTG
CEEECCCCCHHHHHHHHHHCCCHHHCCCCCCCCCHHHHHHHHHHHEECCCCCCEEEEEEC
SGTAAVESMIAALVPENGKLLVIENGVYGERITQIATQYRIAHDVLKHDWMQAPDLARVA
CCHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
EKLDADRAITHVAVIHHETTTGRLNDLDALAAVCRARGVRMLVDGVSSFGAEAIDFAGGD
HHHCHHHHHHEEEEEEECCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHCCCCC
IDALAATANKCLHGVPGAAFVIVRRRALASAASRTYYLDLGRLAKLQDARNTPFTPSVHA
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCEEEEEHHHHHHHHHCCCCCCCCHHHH
YYALVEALREFDEAGGWRARHARYAALAEQVRAGLAARGMPLVLPDGESSVVLRAYRLPA
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCEEEEEECCCC
GVAYEQLHDGLKARGFVIYAGQGGLSSALFRVSTMGAIEPADVERLLDGFTALAR
CCHHHHHHCCHHHCCEEEEECCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLLLNPGPVTLTERVRQSLLQPDLCHRESEFFDLQDEARARLVAAYALDPAEWSAVLMTG
CEEECCCCCHHHHHHHHHHCCCHHHCCCCCCCCCHHHHHHHHHHHEECCCCCCEEEEEEC
SGTAAVESMIAALVPENGKLLVIENGVYGERITQIATQYRIAHDVLKHDWMQAPDLARVA
CCHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
EKLDADRAITHVAVIHHETTTGRLNDLDALAAVCRARGVRMLVDGVSSFGAEAIDFAGGD
HHHCHHHHHHEEEEEEECCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHCCCCC
IDALAATANKCLHGVPGAAFVIVRRRALASAASRTYYLDLGRLAKLQDARNTPFTPSVHA
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCEEEEEHHHHHHHHHCCCCCCCCHHHH
YYALVEALREFDEAGGWRARHARYAALAEQVRAGLAARGMPLVLPDGESSVVLRAYRLPA
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCEEEEEECCCC
GVAYEQLHDGLKARGFVIYAGQGGLSSALFRVSTMGAIEPADVERLLDGFTALAR
CCHHHHHHCCHHHCCEEEEECCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA