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The map label for this gene is mchE [H]

Identifier: 126444777

GI number: 126444777

Start: 1773339

End: 1774634

Strand: Reverse

Name: mchE [H]

Synonym: BURPS668_A1816

Alternate gene names: 126444777

Gene position: 1774634-1773339 (Counterclockwise)

Preceding gene: 126443703

Following gene: 126445456

Centisome position: 56.74

GC content: 63.58

Gene sequence:

>1296_bases
ATGCCTATCTGGATGAACGCTCTGAGAGAGCAGAAGACGCCGCGCAAGCTCACGCGCGGCACGACGTTCGGCACCGTGAT
CAACGGCGTGGTCGACGTGCCGATTTCGATGCGCTTTTTCTGCTATCTGTCGATCATGATGTTCGCGATGTTCATCGTCG
CGCTCGTGCGCCTCACCTACGCGAACACCGAGAGCGTGATGGGGATGCTCACGCCGCGCTCGGGGCTGATCGGCGTCGGC
GCGCCGCCCGGATGGGCGGTGCGCGAGGTGTTCGTCGCGAAGGACCAGCACGTGAAGGCCGGCCAGAAGCTCTTGAGCGT
CACGCGCGACACGAGCTTCGTGTCGCAGGCGAACAACGTGCAGGGCATGCGCGAATCGATCAAGCGGCAGCGCGTGGAGG
TCGGTCAGCAGATCGACGCGGCGAAGCTCGAATATCAATCGACGATCCAGCAGATCAACCAGCAGATCGCCGCGTTCGAC
GAGAGCCGCGGGCTGATCGACAAGCAGATCCAGGACCAGAAGCGGATCGTCTCCGAATACCAGGAGCGGCGCGACCGCGT
GAAGCAACTGCTCAACGAGCAGGTGGTCACGCTCGAGCAGTACAACCAGGTCAACACGCAATACCTGCAGGCGAGCCAGG
CGTACCAGGACCTGATGCTGCGCCGCGCCGACCTCGCGAAGAACGCGATGAAGCTGCGCGGCGATCTCGAAACCGTGCAG
AGCAAGTACGACGGCTCGAACGCCGAGCTGAAGATCAAGCAGGAAGAGCTGAACTCGAAGGAATACAACATCGACGAGAG
CGTGAACCAGGTGCTGTACGCGCCCGCCGACGGCCAGATCGTGCGGCTCGACGTCGTGCAGGGCAGCGTGATCGATCCGC
CCGGCACGCGCGTGGTCGAGATCCTGCCGGCGAAGGCGGACGGGCTCATCGCCGAGCTGTACATTCCGTCGTCGAAGGCC
GGCTTCGTGAAGCCGGGCCAGGAAGTGAAGCTCGCGTACGGCAGCTATCCGGTCGAGAAGTTCGGCACCTATCGCGGCAA
GCTGCTGTCGGTGTCGCCCGTCGCGTTCACCGCGAAGGAGCTGAATCTGCCCGCCGACAACGGCGCGCCGCAGACTTACT
TCAAGAGCTGGGTCGAGCTTGTCGACCGCAAGCCGGCGTTCGAAGGCAAGGCGCTCTCGCTGAAGGCCGGCATGACGCTC
AGGGCGGACATCGTGCTCGAGAAGCGCACGCTGCTCGAATGGCTGTTCGAACCGTTGTATCGGATCCGGCAGCGGATATT
CGGTACGCCCGCGTGA

Upstream 100 bases:

>100_bases
CTGGGAGCACTTCACGCCGTACCTGATGCCATCCCCGTTGCTCGAGCAGAACGCGCGCGCCGCCGCGCAGACGCTGCGCA
GCGCCTGACGAGGCTCGCCC

Downstream 100 bases:

>100_bases
CGGCCGGTGCGTAATGGGTGACAAGCATCGTCGTCGACGTGCGCGCCGCGACTGGCGCGCTCCGGTGTCCTGCTGGCTCG
GCGCGACGCTGCTCGCGTGC

Product: putative secretion protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 431; Mature: 430

Protein sequence:

>431_residues
MPIWMNALREQKTPRKLTRGTTFGTVINGVVDVPISMRFFCYLSIMMFAMFIVALVRLTYANTESVMGMLTPRSGLIGVG
APPGWAVREVFVAKDQHVKAGQKLLSVTRDTSFVSQANNVQGMRESIKRQRVEVGQQIDAAKLEYQSTIQQINQQIAAFD
ESRGLIDKQIQDQKRIVSEYQERRDRVKQLLNEQVVTLEQYNQVNTQYLQASQAYQDLMLRRADLAKNAMKLRGDLETVQ
SKYDGSNAELKIKQEELNSKEYNIDESVNQVLYAPADGQIVRLDVVQGSVIDPPGTRVVEILPAKADGLIAELYIPSSKA
GFVKPGQEVKLAYGSYPVEKFGTYRGKLLSVSPVAFTAKELNLPADNGAPQTYFKSWVELVDRKPAFEGKALSLKAGMTL
RADIVLEKRTLLEWLFEPLYRIRQRIFGTPA

Sequences:

>Translated_431_residues
MPIWMNALREQKTPRKLTRGTTFGTVINGVVDVPISMRFFCYLSIMMFAMFIVALVRLTYANTESVMGMLTPRSGLIGVG
APPGWAVREVFVAKDQHVKAGQKLLSVTRDTSFVSQANNVQGMRESIKRQRVEVGQQIDAAKLEYQSTIQQINQQIAAFD
ESRGLIDKQIQDQKRIVSEYQERRDRVKQLLNEQVVTLEQYNQVNTQYLQASQAYQDLMLRRADLAKNAMKLRGDLETVQ
SKYDGSNAELKIKQEELNSKEYNIDESVNQVLYAPADGQIVRLDVVQGSVIDPPGTRVVEILPAKADGLIAELYIPSSKA
GFVKPGQEVKLAYGSYPVEKFGTYRGKLLSVSPVAFTAKELNLPADNGAPQTYFKSWVELVDRKPAFEGKALSLKAGMTL
RADIVLEKRTLLEWLFEPLYRIRQRIFGTPA
>Mature_430_residues
PIWMNALREQKTPRKLTRGTTFGTVINGVVDVPISMRFFCYLSIMMFAMFIVALVRLTYANTESVMGMLTPRSGLIGVGA
PPGWAVREVFVAKDQHVKAGQKLLSVTRDTSFVSQANNVQGMRESIKRQRVEVGQQIDAAKLEYQSTIQQINQQIAAFDE
SRGLIDKQIQDQKRIVSEYQERRDRVKQLLNEQVVTLEQYNQVNTQYLQASQAYQDLMLRRADLAKNAMKLRGDLETVQS
KYDGSNAELKIKQEELNSKEYNIDESVNQVLYAPADGQIVRLDVVQGSVIDPPGTRVVEILPAKADGLIAELYIPSSKAG
FVKPGQEVKLAYGSYPVEKFGTYRGKLLSVSPVAFTAKELNLPADNGAPQTYFKSWVELVDRKPAFEGKALSLKAGMTLR
ADIVLEKRTLLEWLFEPLYRIRQRIFGTPA

Specific function: Probably involved, in conjunction with mchF, in the secretion of microcin H47 [H]

COG id: COG0845

COG function: function code M; Membrane-fusion protein

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003997
- InterPro:   IPR006143
- InterPro:   IPR006144
- InterPro:   IPR011053 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 48509; Mature: 48377

Theoretical pI: Translated: 9.74; Mature: 9.74

Prosite motif: PS00543 HLYD_FAMILY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHCCCCC
>Mature Secondary Structure 
PIWMNALREQKTPRKLTRGTTFGTVINGVVDVPISMRFFCYLSIMMFAMFIVALVRLTY
CCHHHHHHCCCCCHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
ANTESVMGMLTPRSGLIGVGAPPGWAVREVFVAKDQHVKAGQKLLSVTRDTSFVSQANNV
CCHHHHHEEECCCCCEEECCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
QGMRESIKRQRVEVGQQIDAAKLEYQSTIQQINQQIAAFDESRGLIDKQIQDQKRIVSEY
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
QERRDRVKQLLNEQVVTLEQYNQVNTQYLQASQAYQDLMLRRADLAKNAMKLRGDLETVQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SKYDGSNAELKIKQEELNSKEYNIDESVNQVLYAPADGQIVRLDVVQGSVIDPPGTRVVE
HHCCCCCCEEEEEHHHCCCCCCCCHHHHHHEEECCCCCCEEEEEEECCCEECCCCCEEEE
ILPAKADGLIAELYIPSSKAGFVKPGQEVKLAYGSYPVEKFGTYRGKLLSVSPVAFTAKE
EECCCCCCEEEEEEECCCCCCCCCCCCCEEEEECCCCHHHHCCCCCCEEEECCCEEEHHH
LNLPADNGAPQTYFKSWVELVDRKPAFEGKALSLKAGMTLRADIVLEKRTLLEWLFEPLY
CCCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEECCCEEEEHHHHHHHHHHHHHHHHHH
RIRQRIFGTPA
HHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11181394 [H]