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The map label for this gene is ephD [H]

Identifier: 126444455

GI number: 126444455

Start: 1265879

End: 1266832

Strand: Reverse

Name: ephD [H]

Synonym: BURPS668_A1344

Alternate gene names: 126444455

Gene position: 1266832-1265879 (Counterclockwise)

Preceding gene: 126442696

Following gene: 126445104

Centisome position: 40.51

GC content: 69.92

Gene sequence:

>954_bases
ATGGCGACCGTCCGCGACACGCTGACGGTCCGCTCGGGCGACGTGCGTCTCGCCGTCTACCTGAGCGGGCCGCGCAACGC
CCCGCCCGTGATCCTCGTGCACGGCTATCCCGATTCGGCGCGCGTGTGGGAGCGCGTGCGCGAGCATCTGGACAAACGCT
TTCGCGTGATCGCGTACGACGTGCGCGGCGCGGGCGCGTCCGACGCACCGAAGCGGCGCGCCGACTACAAGCTGTCCGTA
CTCGCGCAGGATCTGCTCGCCGTCGCCGACGTGACGTGCGGCGACCGGCCGTTTCACCTCGTCGGCCACGACTGGGGGTC
GATTCAATGCTGGGAAGCGGCCACCGATCCGGCCGTCAAGGGCCGGCTGGCGTCGTATACGTCGATCTCGGGGCCGTGCC
TCGACCATGTGTTTCGCGCGCCGCTCAATCTGCGGCAGACGCTCAAATCGTGGTACATCGCGTTCTTCCATCTGCCGCTC
GTACCCGAGCTCGTGTGGCGGCTGGGCGGCGCGAAGCTGTGGCCGCTGTGGTTGCGCCGAACCGAGCGCATCGTCGCCGA
TGCCGATCCGGATCAATTGCGCAACGGCCTGAACGGCCTCAAGCTCTACCGCGCGAATTTCATCGAGCGCGCCCGCCGGC
CGCGCGAGCGCTACGCGCAGGCACCCGTGCAGATCATCGTGCCGCGCTACGACCGGTACGTGACGCCCGCCCTCACCCGC
GGCCTCGACCGCTGGCTGGGCGCGCATCGCCGTGACGAAATCGCCGCGTCGCACTGGACGGTGATCCGCGACGCCGCGCT
GATCGCCGCACGGATCGGCCGGTTCGCGGCCGCGCACGAGCCGAAGCGGCACGCGATCGCGGCCGGCGGCGCGAAATCCG
GCGGCCAGCCGCGTGCGAAACAGCGCACGAATCAACAGGCATCGGCCGGCAGGCGCTTGAAAAGCGTTTCGTAG

Upstream 100 bases:

>100_bases
ACATCGACGCCGCGAACGAGCGCTATGCCGACCAGGTCGCGCCACGGCGCGTGCCGTTGCATTCGCTGCCCGAGCACCAG
CACGCGTAAGCGAACGAGCG

Downstream 100 bases:

>100_bases
GCGATCGCGGGTCCGCTCCCGTCGATCGGGGCCCGCCGCCCGGCGGGGCCTTGGCGCCCTCGATGCTTCCGTCACCGCGC
GACGTCGGCTCGGCGCGTCG

Product: alpha/beta fold family hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 317; Mature: 316

Protein sequence:

>317_residues
MATVRDTLTVRSGDVRLAVYLSGPRNAPPVILVHGYPDSARVWERVREHLDKRFRVIAYDVRGAGASDAPKRRADYKLSV
LAQDLLAVADVTCGDRPFHLVGHDWGSIQCWEAATDPAVKGRLASYTSISGPCLDHVFRAPLNLRQTLKSWYIAFFHLPL
VPELVWRLGGAKLWPLWLRRTERIVADADPDQLRNGLNGLKLYRANFIERARRPRERYAQAPVQIIVPRYDRYVTPALTR
GLDRWLGAHRRDEIAASHWTVIRDAALIAARIGRFAAAHEPKRHAIAAGGAKSGGQPRAKQRTNQQASAGRRLKSVS

Sequences:

>Translated_317_residues
MATVRDTLTVRSGDVRLAVYLSGPRNAPPVILVHGYPDSARVWERVREHLDKRFRVIAYDVRGAGASDAPKRRADYKLSV
LAQDLLAVADVTCGDRPFHLVGHDWGSIQCWEAATDPAVKGRLASYTSISGPCLDHVFRAPLNLRQTLKSWYIAFFHLPL
VPELVWRLGGAKLWPLWLRRTERIVADADPDQLRNGLNGLKLYRANFIERARRPRERYAQAPVQIIVPRYDRYVTPALTR
GLDRWLGAHRRDEIAASHWTVIRDAALIAARIGRFAAAHEPKRHAIAAGGAKSGGQPRAKQRTNQQASAGRRLKSVS
>Mature_316_residues
ATVRDTLTVRSGDVRLAVYLSGPRNAPPVILVHGYPDSARVWERVREHLDKRFRVIAYDVRGAGASDAPKRRADYKLSVL
AQDLLAVADVTCGDRPFHLVGHDWGSIQCWEAATDPAVKGRLASYTSISGPCLDHVFRAPLNLRQTLKSWYIAFFHLPLV
PELVWRLGGAKLWPLWLRRTERIVADADPDQLRNGLNGLKLYRANFIERARRPRERYAQAPVQIIVPRYDRYVTPALTRG
LDRWLGAHRRDEIAASHWTVIRDAALIAARIGRFAAAHEPKRHAIAAGGAKSGGQPRAKQRTNQQASAGRRLKSVS

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI218777837, Length=169, Percent_Identity=30.7692307692308, Blast_Score=86, Evalue=6e-17,
Organism=Homo sapiens, GI218777840, Length=286, Percent_Identity=24.1258741258741, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI13376164, Length=286, Percent_Identity=24.1258741258741, Blast_Score=78, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17562298, Length=166, Percent_Identity=29.5180722891566, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17554012, Length=292, Percent_Identity=23.2876712328767, Blast_Score=74, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00561 Abhydrolase_1; PF00106 adh_short [H]

EC number: NA

Molecular weight: Translated: 35559; Mature: 35428

Theoretical pI: Translated: 11.19; Mature: 11.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATVRDTLTVRSGDVRLAVYLSGPRNAPPVILVHGYPDSARVWERVREHLDKRFRVIAYD
CCCCCCEEEEECCCEEEEEEECCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHEEEEEEE
VRGAGASDAPKRRADYKLSVLAQDLLAVADVTCGDRPFHLVGHDWGSIQCWEAATDPAVK
ECCCCCCCCCCHHCCHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCEEEECCCCCHHHH
GRLASYTSISGPCLDHVFRAPLNLRQTLKSWYIAFFHLPLVPELVWRLGGAKLWPLWLRR
CHHHHHCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
TERIVADADPDQLRNGLNGLKLYRANFIERARRPRERYAQAPVQIIVPRYDRYVTPALTR
HHHHHCCCCHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHCCCEEEEECCCCCCCCHHHHH
GLDRWLGAHRRDEIAASHWTVIRDAALIAARIGRFAAAHEPKRHAIAAGGAKSGGQPRAK
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHEEECCCCCCCCCCCHH
QRTNQQASAGRRLKSVS
HHCCHHHHHHHHHHCCC
>Mature Secondary Structure 
ATVRDTLTVRSGDVRLAVYLSGPRNAPPVILVHGYPDSARVWERVREHLDKRFRVIAYD
CCCCCEEEEECCCEEEEEEECCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHEEEEEEE
VRGAGASDAPKRRADYKLSVLAQDLLAVADVTCGDRPFHLVGHDWGSIQCWEAATDPAVK
ECCCCCCCCCCHHCCHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCEEEECCCCCHHHH
GRLASYTSISGPCLDHVFRAPLNLRQTLKSWYIAFFHLPLVPELVWRLGGAKLWPLWLRR
CHHHHHCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
TERIVADADPDQLRNGLNGLKLYRANFIERARRPRERYAQAPVQIIVPRYDRYVTPALTR
HHHHHCCCCHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHCCCEEEEECCCCCCCCHHHHH
GLDRWLGAHRRDEIAASHWTVIRDAALIAARIGRFAAAHEPKRHAIAAGGAKSGGQPRAK
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHEEECCCCCCCCCCCHH
QRTNQQASAGRRLKSVS
HHCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]