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The map label for this gene is spaR [H]

Identifier: 126444373

GI number: 126444373

Start: 2102987

End: 2103730

Strand: Reverse

Name: spaR [H]

Synonym: BURPS668_A2165

Alternate gene names: 126444373

Gene position: 2103730-2102987 (Counterclockwise)

Preceding gene: 126445290

Following gene: 126443467

Centisome position: 67.27

GC content: 68.95

Gene sequence:

>744_bases
ATGCAAGCGTTCTACCGGCACGCCGGCGCGATCGCGATCGCGTACGCGCGCGTCGCGCCGGTGTTCTATCTGCTGCCGTT
CCTGAACGACCGGACGATCGTCAACGGCATCGTGAAGAACACGATCGTGTTCGCGATCATCCTCGGGCTGTGGCCGAGCT
TCGCGCATCCGCCGCTGCAAGGCGGCGCGCTCGCCGGCGTCGCGCTGACGGAGGCGGCCGCGGGCGTCGTGCTCGGCGTC
GCGCTGTCGCTGCCGTTCTGGGTCGCGACGGCGGTGGGCGAGCTGATCGACAACCAGCGCGGCGCGACGATCAGCGATTC
GATCGACCCGGCGACGGGCGTCGAAGCGTCGGCGCTCGCGCCGTTCGTGAGCCTGTTCTATGCGGCCGCGTTCCTGCAGC
AGGGCGGGATGCTGACGATCGTCGGCGCGCTCGAGGCGAGCTACGCGACGGTGCCCGCCGGCGCGCTGTTCTCGGTCGAT
CTGCCGCGCATCGGCGCGCTGTTGACCGATCTCGTCGCGCACGGGCTCGCGCTCGCCGCGCCCGTGCTGATCGTGATGTT
CGTCACCGATGCGCTGCTCGGGCTGTTCTCGCGCTTCTGCCCGCAGGTCAACGCGTTCTCGCTGTCGCTGACGGTCAAGA
GCATCGTCGCGTTCGCCGTGTTCCACCTGTACTTCGTATACGCGGCGCCGCACGAGCTGACGGCGCTGCTGCGCGTGCAT
CCTTTCAGCAGCCTGGTGAAGTGA

Upstream 100 bases:

>100_bases
CGGCGGCAAGCTGCTCGCGTTCGCGACCGAGATGCTGTCGATCGGGCTGCGCTGAGCCGCTTCACGTCACGTCATGCCGA
GCGACACGATGGATGTCTTG

Downstream 100 bases:

>100_bases
GCGATGGCCGAGAAAACCGAGAAGCCGACCGCGAAGAAGCTGCGCGACGCGGCGAAGAAGGGGCAGACGTTCAAGGCGCG
GGACATCGTCGCGCTCATCG

Product: type III secretion protein SpaR/YscT/HrcT

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 247; Mature: 247

Protein sequence:

>247_residues
MQAFYRHAGAIAIAYARVAPVFYLLPFLNDRTIVNGIVKNTIVFAIILGLWPSFAHPPLQGGALAGVALTEAAAGVVLGV
ALSLPFWVATAVGELIDNQRGATISDSIDPATGVEASALAPFVSLFYAAAFLQQGGMLTIVGALEASYATVPAGALFSVD
LPRIGALLTDLVAHGLALAAPVLIVMFVTDALLGLFSRFCPQVNAFSLSLTVKSIVAFAVFHLYFVYAAPHELTALLRVH
PFSSLVK

Sequences:

>Translated_247_residues
MQAFYRHAGAIAIAYARVAPVFYLLPFLNDRTIVNGIVKNTIVFAIILGLWPSFAHPPLQGGALAGVALTEAAAGVVLGV
ALSLPFWVATAVGELIDNQRGATISDSIDPATGVEASALAPFVSLFYAAAFLQQGGMLTIVGALEASYATVPAGALFSVD
LPRIGALLTDLVAHGLALAAPVLIVMFVTDALLGLFSRFCPQVNAFSLSLTVKSIVAFAVFHLYFVYAAPHELTALLRVH
PFSSLVK
>Mature_247_residues
MQAFYRHAGAIAIAYARVAPVFYLLPFLNDRTIVNGIVKNTIVFAIILGLWPSFAHPPLQGGALAGVALTEAAAGVVLGV
ALSLPFWVATAVGELIDNQRGATISDSIDPATGVEASALAPFVSLFYAAAFLQQGGMLTIVGALEASYATVPAGALFSVD
LPRIGALLTDLVAHGLALAAPVLIVMFVTDALLGLFSRFCPQVNAFSLSLTVKSIVAFAVFHLYFVYAAPHELTALLRVH
PFSSLVK

Specific function: Involved in a secretory pathway responsible for the surface presentation of determinants needed for the entry of Salmonella species into mammalian cells [H]

COG id: COG4791

COG function: function code U; Type III secretory pathway, component EscT

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fliR/mopE/spaR family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002010
- InterPro:   IPR006304 [H]

Pfam domain/function: PF01311 Bac_export_1 [H]

EC number: NA

Molecular weight: Translated: 25867; Mature: 25867

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQAFYRHAGAIAIAYARVAPVFYLLPFLNDRTIVNGIVKNTIVFAIILGLWPSFAHPPLQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
GGALAGVALTEAAAGVVLGVALSLPFWVATAVGELIDNQRGATISDSIDPATGVEASALA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHH
PFVSLFYAAAFLQQGGMLTIVGALEASYATVPAGALFSVDLPRIGALLTDLVAHGLALAA
HHHHHHHHHHHHHCCCEEEEEEHHHHHHHCCCCCCEEECCHHHHHHHHHHHHHHHHHHHH
PVLIVMFVTDALLGLFSRFCPQVNAFSLSLTVKSIVAFAVFHLYFVYAAPHELTALLRVH
HHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHC
PFSSLVK
CHHHHCC
>Mature Secondary Structure
MQAFYRHAGAIAIAYARVAPVFYLLPFLNDRTIVNGIVKNTIVFAIILGLWPSFAHPPLQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
GGALAGVALTEAAAGVVLGVALSLPFWVATAVGELIDNQRGATISDSIDPATGVEASALA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHH
PFVSLFYAAAFLQQGGMLTIVGALEASYATVPAGALFSVDLPRIGALLTDLVAHGLALAA
HHHHHHHHHHHHHCCCEEEEEEHHHHHHHCCCCCCEEECCHHHHHHHHHHHHHHHHHHHH
PVLIVMFVTDALLGLFSRFCPQVNAFSLSLTVKSIVAFAVFHLYFVYAAPHELTALLRVH
HHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHC
PFSSLVK
CHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8404849; 11677609 [H]