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The map label for this gene is 126444295

Identifier: 126444295

GI number: 126444295

Start: 1268709

End: 1270298

Strand: Reverse

Name: 126444295

Synonym: BURPS668_A1347

Alternate gene names: NA

Gene position: 1270298-1268709 (Counterclockwise)

Preceding gene: 126444799

Following gene: 126443407

Centisome position: 40.62

GC content: 65.72

Gene sequence:

>1590_bases
ATGAACGCGCGCAATATGTCCTTCGGTCCGCTCGACAGCACAAACCGCGAAGAAACGCTCGATATCGCCATCATCGGCAC
CGGCTTTTCCGGGCTCGGCATGGCGATTCGCCTCCGGCAAACCGGCAACCAGGATTTCGCGGTGTTCGAAAAGGCCAGCT
CGGTCGGCGGCACCTGGCGGGACAACCATTATCCCGGCTGCGCATGCGACGTTCAGTCGCACGTCTATTCGTTCTCGTTT
GCACCGAACCCGCGCTGGACGCGCATGTTCGCGCCGCAGCCGGAAATTCGCGCGTACATGGAAGACTGCGTGCAGCGCTT
CAACGTGGGCTCGCATCTGCGCTTCGATCATGAGCTCGTCAACGCGACCTACGACGAAACCGCGCACCGCTGGCGCCTCA
CGTTCGCGAACGGCAAGCGCGTCTGCGCGCGCGTGCTCGTGTCCGGCATGGGCGGCCTGTCGCGCGCCGCGTACCCGAAC
ATTCCCGGCATCGAGACGTTCAAGGGCGAAGCGTTCCACTCGCAGCACTGGAAACACGATTACGCGCTCGAAGGCAAACG
CGTCGCCGTGATCGGCACGGGCGCGAGCGCGATCCAGTTCGTCCCGCAGATCGCGCCGCGCGTCGCGAAGCTCGCGCTGT
TCCAGCGCACGCCGCCGTGGATCATGCCGAAGCCGGACCGCGCGGTGAGCGGCGTCGAGCAGTGGCTGTTCCGCAATCTG
CCGTTCACGCAGAAGCTGATGCGCGCGGGCCTGTACTGGATGCTCGAATCGCGCGTGCTGGGCTTCGCCGTGCACCCGTC
GACGATGAAGCTCGTGCAGAAGCTCGCGCTGCGCCACATCGACAAGCAGATCTCCGAGCCGGAACTGCGCGCCGCGGTGA
CGCCCGACTACACGATCGGCTGCAAGCGGATCCTGATGTCGAACGATTACTATCCGGCGCTCACGCGCAAGAACGTCGAC
GTGATCACGACGGGCATCGAGCGGATCGAGGAAGACGCCGTCGTCACGACGGACGGCAAGCGCCACGAAGTCGACTGCCT
GATCTACGGCACGGGCTTCCAGATCAACAACCCGTTCCCGCGCGGCACGATCGTCGGCCGCGGCGGCGTCGACGTCGTCG
ATGCGTGGCGCGACGGCCTGCACGCCTACCTGGGCGCGACGGTGCCCGGCTACCCGAACTGGTTCATCCTGATGGGCCCG
AACACGGGCCTCGGCCACAACTCGATGGTGTACATGATCGAATCGCAGATCGAGTACGTGCTCGGCGCGCTGAAGGCGAT
GCGCACCGAGCGCGCCGAGGCGATCGAAGTGCGCCCGCTCGTCGAGCTCGAATACAACAACCGCATCCAGAACAAGCTGA
AGGGCACGGTCTGGTCGACGGGCGGCTGCAGCAGCTGGTATCTCGATCCGCGCACCGGCAAGAACACGACGCTGTGGCCG
ACCTTCACGTGGCGCTTCCGGCAGGAAACCGCGTTCTTCTCGACGGCCGATTACCACCTGTACTACGCGAATCCGCGTCA
GAGCCCGCAGCCGGTGCCGGCGTTGGCGAGCGCCGCCGCCGCGACGACGACCGCCGAGACGACCGCCTGA

Upstream 100 bases:

>100_bases
AGAGGGCTATGTCTACCCGGCTTGCGGTTTCGACTTTCACGAACTATTGTTACATCCATCAATGTAACAGTAAAAAATGA
GCCTAAATGGAGACGCTTGG

Downstream 100 bases:

>100_bases
GCCCCGAACCCACACGAGCCTACGACGATGAAATCCTTCTCCAACAAAGTCGCCGCGATCACGGGCGCCGGCTCGGGCAT
GGGCCGCTCGCTCGCGGTGC

Product: putative monooxygenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 529; Mature: 529

Protein sequence:

>529_residues
MNARNMSFGPLDSTNREETLDIAIIGTGFSGLGMAIRLRQTGNQDFAVFEKASSVGGTWRDNHYPGCACDVQSHVYSFSF
APNPRWTRMFAPQPEIRAYMEDCVQRFNVGSHLRFDHELVNATYDETAHRWRLTFANGKRVCARVLVSGMGGLSRAAYPN
IPGIETFKGEAFHSQHWKHDYALEGKRVAVIGTGASAIQFVPQIAPRVAKLALFQRTPPWIMPKPDRAVSGVEQWLFRNL
PFTQKLMRAGLYWMLESRVLGFAVHPSTMKLVQKLALRHIDKQISEPELRAAVTPDYTIGCKRILMSNDYYPALTRKNVD
VITTGIERIEEDAVVTTDGKRHEVDCLIYGTGFQINNPFPRGTIVGRGGVDVVDAWRDGLHAYLGATVPGYPNWFILMGP
NTGLGHNSMVYMIESQIEYVLGALKAMRTERAEAIEVRPLVELEYNNRIQNKLKGTVWSTGGCSSWYLDPRTGKNTTLWP
TFTWRFRQETAFFSTADYHLYYANPRQSPQPVPALASAAAATTTAETTA

Sequences:

>Translated_529_residues
MNARNMSFGPLDSTNREETLDIAIIGTGFSGLGMAIRLRQTGNQDFAVFEKASSVGGTWRDNHYPGCACDVQSHVYSFSF
APNPRWTRMFAPQPEIRAYMEDCVQRFNVGSHLRFDHELVNATYDETAHRWRLTFANGKRVCARVLVSGMGGLSRAAYPN
IPGIETFKGEAFHSQHWKHDYALEGKRVAVIGTGASAIQFVPQIAPRVAKLALFQRTPPWIMPKPDRAVSGVEQWLFRNL
PFTQKLMRAGLYWMLESRVLGFAVHPSTMKLVQKLALRHIDKQISEPELRAAVTPDYTIGCKRILMSNDYYPALTRKNVD
VITTGIERIEEDAVVTTDGKRHEVDCLIYGTGFQINNPFPRGTIVGRGGVDVVDAWRDGLHAYLGATVPGYPNWFILMGP
NTGLGHNSMVYMIESQIEYVLGALKAMRTERAEAIEVRPLVELEYNNRIQNKLKGTVWSTGGCSSWYLDPRTGKNTTLWP
TFTWRFRQETAFFSTADYHLYYANPRQSPQPVPALASAAAATTTAETTA
>Mature_529_residues
MNARNMSFGPLDSTNREETLDIAIIGTGFSGLGMAIRLRQTGNQDFAVFEKASSVGGTWRDNHYPGCACDVQSHVYSFSF
APNPRWTRMFAPQPEIRAYMEDCVQRFNVGSHLRFDHELVNATYDETAHRWRLTFANGKRVCARVLVSGMGGLSRAAYPN
IPGIETFKGEAFHSQHWKHDYALEGKRVAVIGTGASAIQFVPQIAPRVAKLALFQRTPPWIMPKPDRAVSGVEQWLFRNL
PFTQKLMRAGLYWMLESRVLGFAVHPSTMKLVQKLALRHIDKQISEPELRAAVTPDYTIGCKRILMSNDYYPALTRKNVD
VITTGIERIEEDAVVTTDGKRHEVDCLIYGTGFQINNPFPRGTIVGRGGVDVVDAWRDGLHAYLGATVPGYPNWFILMGP
NTGLGHNSMVYMIESQIEYVLGALKAMRTERAEAIEVRPLVELEYNNRIQNKLKGTVWSTGGCSSWYLDPRTGKNTTLWP
TFTWRFRQETAFFSTADYHLYYANPRQSPQPVPALASAAAATTTAETTA

Specific function: Unknown

COG id: COG2072

COG function: function code P; Predicted flavoprotein involved in K+ transport

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-binding monooxygenase family [H]

Homologues:

Organism=Homo sapiens, GI4503757, Length=366, Percent_Identity=24.3169398907104, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI4503759, Length=356, Percent_Identity=21.9101123595506, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI4503755, Length=454, Percent_Identity=20.4845814977974, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI50541965, Length=375, Percent_Identity=21.0666666666667, Blast_Score=73, Evalue=6e-13,
Organism=Homo sapiens, GI50541961, Length=375, Percent_Identity=21.0666666666667, Blast_Score=73, Evalue=6e-13,
Organism=Homo sapiens, GI221316672, Length=365, Percent_Identity=23.2876712328767, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI221316674, Length=367, Percent_Identity=23.1607629427793, Blast_Score=70, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI25145785, Length=357, Percent_Identity=21.2885154061625, Blast_Score=77, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020946 [H]

Pfam domain/function: PF00743 FMO-like [H]

EC number: NA

Molecular weight: Translated: 59329; Mature: 59329

Theoretical pI: Translated: 9.03; Mature: 9.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNARNMSFGPLDSTNREETLDIAIIGTGFSGLGMAIRLRQTGNQDFAVFEKASSVGGTWR
CCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCEEEEEECCCCCCEEEEEHHHHCCCCCC
DNHYPGCACDVQSHVYSFSFAPNPRWTRMFAPQPEIRAYMEDCVQRFNVGSHLRFDHELV
CCCCCCEEEECCCCEEEEEECCCCCEEEEECCCHHHHHHHHHHHHHCCCCCCEEECHHHH
NATYDETAHRWRLTFANGKRVCARVLVSGMGGLSRAAYPNIPGIETFKGEAFHSQHWKHD
CCHHHCCCEEEEEEECCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCC
YALEGKRVAVIGTGASAIQFVPQIAPRVAKLALFQRTPPWIMPKPDRAVSGVEQWLFRNL
EEECCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCC
PFTQKLMRAGLYWMLESRVLGFAVHPSTMKLVQKLALRHIDKQISEPELRAAVTPDYTIG
CHHHHHHHHHHHHHHHCCEEEEEECCHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCHHC
CKRILMSNDYYPALTRKNVDVITTGIERIEEDAVVTTDGKRHEVDCLIYGTGFQINNPFP
HHHEEECCCCCCCCCCCCCCEEEHHHHHHCCCCEEECCCCCEEEEEEEEECCEEECCCCC
RGTIVGRGGVDVVDAWRDGLHAYLGATVPGYPNWFILMGPNTGLGHNSMVYMIESQIEYV
CCEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCEEEEEHHHHHHH
LGALKAMRTERAEAIEVRPLVELEYNNRIQNKLKGTVWSTGGCSSWYLDPRTGKNTTLWP
HHHHHHHHHHHCCEEEECEEEEEECCCHHHHHHCCCEEECCCCCCEEECCCCCCCCEECC
TFTWRFRQETAFFSTADYHLYYANPRQSPQPVPALASAAAATTTAETTA
EEEEEEECCCEEEEECCEEEEECCCCCCCCCCHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MNARNMSFGPLDSTNREETLDIAIIGTGFSGLGMAIRLRQTGNQDFAVFEKASSVGGTWR
CCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCEEEEEECCCCCCEEEEEHHHHCCCCCC
DNHYPGCACDVQSHVYSFSFAPNPRWTRMFAPQPEIRAYMEDCVQRFNVGSHLRFDHELV
CCCCCCEEEECCCCEEEEEECCCCCEEEEECCCHHHHHHHHHHHHHCCCCCCEEECHHHH
NATYDETAHRWRLTFANGKRVCARVLVSGMGGLSRAAYPNIPGIETFKGEAFHSQHWKHD
CCHHHCCCEEEEEEECCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCC
YALEGKRVAVIGTGASAIQFVPQIAPRVAKLALFQRTPPWIMPKPDRAVSGVEQWLFRNL
EEECCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCC
PFTQKLMRAGLYWMLESRVLGFAVHPSTMKLVQKLALRHIDKQISEPELRAAVTPDYTIG
CHHHHHHHHHHHHHHHCCEEEEEECCHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCHHC
CKRILMSNDYYPALTRKNVDVITTGIERIEEDAVVTTDGKRHEVDCLIYGTGFQINNPFP
HHHEEECCCCCCCCCCCCCCEEEHHHHHHCCCCEEECCCCCEEEEEEEEECCEEECCCCC
RGTIVGRGGVDVVDAWRDGLHAYLGATVPGYPNWFILMGPNTGLGHNSMVYMIESQIEYV
CCEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCEEEEEHHHHHHH
LGALKAMRTERAEAIEVRPLVELEYNNRIQNKLKGTVWSTGGCSSWYLDPRTGKNTTLWP
HHHHHHHHHHHCCEEEECEEEEEECCCHHHHHHCCCEEECCCCCCEEECCCCCCCCEECC
TFTWRFRQETAFFSTADYHLYYANPRQSPQPVPALASAAAATTTAETTA
EEEEEEECCCEEEEECCEEEEECCCCCCCCCCHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]