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The map label for this gene is sdaA [H]

Identifier: 126444199

GI number: 126444199

Start: 1894813

End: 1896327

Strand: Reverse

Name: sdaA [H]

Synonym: BURPS668_A1955

Alternate gene names: 126444199

Gene position: 1896327-1894813 (Counterclockwise)

Preceding gene: 126442308

Following gene: 126443706

Centisome position: 60.63

GC content: 67.46

Gene sequence:

>1515_bases
ATGGCCGTCTGTCGCGGCGGTTGGCGGCGGCGTCCCACGCCGATGCCGTTTTTGTTCTATCGGCGGATTTTACGCTTTGA
TGTACTGACGCCCAACGTCAACCAAGCATCGTCACGCAAGGGCAGCCAGATGAACGTCAGCGTTTTCGATCTGTTCAAGA
TCGGCATCGGTCCGTCGAGCTCGCATACCGTCGGGCCGATGATCGCCGCGTGCCGGTTCGCGTCGCACGTCGAGGACGCG
AACCTGCTCGGCTTCGTGCGCCGCGTGCGGGCCGAGCTGTACGGCTCGCTCGGCGCGACGGGCAAGGGCCACGGCACCGA
CAAGGCGGTGCTGCTCGGCCTCGAAGGGCACTTGCCCGATTCGGTCGACCCCGATCTGATCGAGCCCCGCTTGAAGGCGA
TCCGCGCGGAGAAGTCGCTCGCGTTGCTCGGCAAGCGCGGCATCCGCTTCGACGAGAAGGACGACATCGGCTTCTACCGC
AAGCTGATGAGCGGCACGAGCGTCGTCCATCCGAACGGCATGCGCTTCCAGGCGTTCGACGAGCACGGCCAGTTGCTCGT
CGAGAAGGAGTATTACTCGGTCGGCGGCGGCTTCGTCGTCAATCGTGACGGCGATCGCGTGAACGGCGTGCGCGCGGCGG
CCGACGTGCCGTATCCGTTTCGCACCGGCGACGATCTGATGCGCGCGTGCCGCGCGAGCGGCCTGTCGATCGCCGAGCTC
ACGTTTCGCAACGAGTGCGCGCTGCGCCCGGCCGACGAGGTGCGCGCGGGCCTCGTCGCGATCTGGAGGACGATGGCCGC
GTGCGTCGAGCGCGGCTGCAAGGCCGACGGCGAGCTGCCCGGCCCGATGCGCGTGAAGCGCCGCGCGGCCGAGCTCTACA
CGCGGCTGCGTGATCGGTCGGAGGAATCGCTGCGCGATCCGCTGTCGATGCTCGACTGGGTAAACCTCTATGCGATGGCG
GTCAACGAGGAGAACGCGGCGGGCGGGCGTGTCGTCACCGCGCCGACGAACGGCGCGGCGGGCGTGATTCCGGCCGTGCT
CCATTACTACGTGAAGTTCGTGCCGGGCTCGAACGAGCAGGGGATCGTCGATTTCCTGCTGACCGCCGCCGCGATCGGGA
TCATCTACAAGGAAACCGCGTCGATCTCCGGCGCGGAGGTCGGCTGCCAGGGCGAGGTGGGCGTCGCGTGCTCGATGGCC
GCGGCCGCGCTCGCCGCGGTAATGGGCGGCACGCCCGGCCAGGTCGAGAACGCGGCCGAGATCGGCATGGAGCACAACCT
CGGGATGACGTGCGATCCCGTGGGCGGCCTCGTGCAGATCCCGTGCATCGAGCGCAACGCGATGGGCGCGATCAAGGCGC
TCAACGCGTCGCGCATCGCGCTCAAGGGCGACGGCCAGCACTACGTGTCGCTCGATTCCGTCATCAAGACGATGCGCGAG
ACGGGCGCCGACATGAAGACGAAATACAAGGAAACGTCGCGCGGCGGCCTCGCCGTGAACGTCATCGAATGCTAA

Upstream 100 bases:

>100_bases
CCGAAGGCCGCCCGCCGCGCAGTCCGTACTGCGAGCGTCGCCGATCGGGCCGCGCGGAACTTGTGTTTTTTCGCCGCGAA
CCATCGCCGAAACGCACCGG

Downstream 100 bases:

>100_bases
TGAAGGGTCCATCAACATGAGCCGCTACTCGATATTCAGCCTGTTTCGCAACGGCCTGTCGTATCACGAGAACTGGGAAA
AGCAGTGGAAGAGCCCGGAG

Product: L-serine ammonia-lyase

Products: NA

Alternate protein names: SDH; L-serine deaminase; L-SD [H]

Number of amino acids: Translated: 504; Mature: 503

Protein sequence:

>504_residues
MAVCRGGWRRRPTPMPFLFYRRILRFDVLTPNVNQASSRKGSQMNVSVFDLFKIGIGPSSSHTVGPMIAACRFASHVEDA
NLLGFVRRVRAELYGSLGATGKGHGTDKAVLLGLEGHLPDSVDPDLIEPRLKAIRAEKSLALLGKRGIRFDEKDDIGFYR
KLMSGTSVVHPNGMRFQAFDEHGQLLVEKEYYSVGGGFVVNRDGDRVNGVRAAADVPYPFRTGDDLMRACRASGLSIAEL
TFRNECALRPADEVRAGLVAIWRTMAACVERGCKADGELPGPMRVKRRAAELYTRLRDRSEESLRDPLSMLDWVNLYAMA
VNEENAAGGRVVTAPTNGAAGVIPAVLHYYVKFVPGSNEQGIVDFLLTAAAIGIIYKETASISGAEVGCQGEVGVACSMA
AAALAAVMGGTPGQVENAAEIGMEHNLGMTCDPVGGLVQIPCIERNAMGAIKALNASRIALKGDGQHYVSLDSVIKTMRE
TGADMKTKYKETSRGGLAVNVIEC

Sequences:

>Translated_504_residues
MAVCRGGWRRRPTPMPFLFYRRILRFDVLTPNVNQASSRKGSQMNVSVFDLFKIGIGPSSSHTVGPMIAACRFASHVEDA
NLLGFVRRVRAELYGSLGATGKGHGTDKAVLLGLEGHLPDSVDPDLIEPRLKAIRAEKSLALLGKRGIRFDEKDDIGFYR
KLMSGTSVVHPNGMRFQAFDEHGQLLVEKEYYSVGGGFVVNRDGDRVNGVRAAADVPYPFRTGDDLMRACRASGLSIAEL
TFRNECALRPADEVRAGLVAIWRTMAACVERGCKADGELPGPMRVKRRAAELYTRLRDRSEESLRDPLSMLDWVNLYAMA
VNEENAAGGRVVTAPTNGAAGVIPAVLHYYVKFVPGSNEQGIVDFLLTAAAIGIIYKETASISGAEVGCQGEVGVACSMA
AAALAAVMGGTPGQVENAAEIGMEHNLGMTCDPVGGLVQIPCIERNAMGAIKALNASRIALKGDGQHYVSLDSVIKTMRE
TGADMKTKYKETSRGGLAVNVIEC
>Mature_503_residues
AVCRGGWRRRPTPMPFLFYRRILRFDVLTPNVNQASSRKGSQMNVSVFDLFKIGIGPSSSHTVGPMIAACRFASHVEDAN
LLGFVRRVRAELYGSLGATGKGHGTDKAVLLGLEGHLPDSVDPDLIEPRLKAIRAEKSLALLGKRGIRFDEKDDIGFYRK
LMSGTSVVHPNGMRFQAFDEHGQLLVEKEYYSVGGGFVVNRDGDRVNGVRAAADVPYPFRTGDDLMRACRASGLSIAELT
FRNECALRPADEVRAGLVAIWRTMAACVERGCKADGELPGPMRVKRRAAELYTRLRDRSEESLRDPLSMLDWVNLYAMAV
NEENAAGGRVVTAPTNGAAGVIPAVLHYYVKFVPGSNEQGIVDFLLTAAAIGIIYKETASISGAEVGCQGEVGVACSMAA
AALAAVMGGTPGQVENAAEIGMEHNLGMTCDPVGGLVQIPCIERNAMGAIKALNASRIALKGDGQHYVSLDSVIKTMRET
GADMKTKYKETSRGGLAVNVIEC

Specific function: Deaminates Also Threonine, Particularly When It Is Present In High Concentration. [C]

COG id: COG1760

COG function: function code E; L-serine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-sulfur dependent L-serine dehydratase family [H]

Homologues:

Organism=Escherichia coli, GI1789161, Length=462, Percent_Identity=51.0822510822511, Blast_Score=458, Evalue=1e-130,
Organism=Escherichia coli, GI1788116, Length=460, Percent_Identity=50.2173913043478, Blast_Score=449, Evalue=1e-127,
Organism=Escherichia coli, GI48994925, Length=458, Percent_Identity=51.528384279476, Blast_Score=444, Evalue=1e-126,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004644
- InterPro:   IPR005130
- InterPro:   IPR005131 [H]

Pfam domain/function: PF03313 SDH_alpha; PF03315 SDH_beta [H]

EC number: =4.3.1.17 [H]

Molecular weight: Translated: 54240; Mature: 54109

Theoretical pI: Translated: 8.34; Mature: 8.34

Prosite motif: PS00159 ALDOLASE_KDPG_KHG_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVCRGGWRRRPTPMPFLFYRRILRFDVLTPNVNQASSRKGSQMNVSVFDLFKIGIGPSS
CCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHCCCCCCEEEEHEEEEEECCCCCC
SHTVGPMIAACRFASHVEDANLLGFVRRVRAELYGSLGATGKGHGTDKAVLLGLEGHLPD
CCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCC
SVDPDLIEPRLKAIRAEKSLALLGKRGIRFDEKDDIGFYRKLMSGTSVVHPNGMRFQAFD
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCEECCCCCEEEEEC
EHGQLLVEKEYYSVGGGFVVNRDGDRVNGVRAAADVPYPFRTGDDLMRACRASGLSIAEL
CCCCEEEEEHHEECCCCEEEECCCCCCCCEEEECCCCCCCCCCHHHHHHHHHCCCEEEEE
TFRNECALRPADEVRAGLVAIWRTMAACVERGCKADGELPGPMRVKRRAAELYTRLRDRS
EECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCC
EESLRDPLSMLDWVNLYAMAVNEENAAGGRVVTAPTNGAAGVIPAVLHYYVKFVPGSNEQ
HHHHHHHHHHHHHHHHEEEEECCCCCCCCEEEECCCCCCCHHHHHHHHHHHEECCCCCCC
GIVDFLLTAAAIGIIYKETASISGAEVGCQGEVGVACSMAAAALAAVMGGTPGQVENAAE
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHH
IGMEHNLGMTCDPVGGLVQIPCIERNAMGAIKALNASRIALKGDGQHYVSLDSVIKTMRE
HCCCCCCCCCCCCCCCEEECCEECCCHHHHHHHCCCCEEEEECCCCEEEEHHHHHHHHHH
TGADMKTKYKETSRGGLAVNVIEC
CCCCHHHHHHHCCCCCEEEEEECC
>Mature Secondary Structure 
AVCRGGWRRRPTPMPFLFYRRILRFDVLTPNVNQASSRKGSQMNVSVFDLFKIGIGPSS
CCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHCCCCCCEEEEHEEEEEECCCCCC
SHTVGPMIAACRFASHVEDANLLGFVRRVRAELYGSLGATGKGHGTDKAVLLGLEGHLPD
CCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCC
SVDPDLIEPRLKAIRAEKSLALLGKRGIRFDEKDDIGFYRKLMSGTSVVHPNGMRFQAFD
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCEECCCCCEEEEEC
EHGQLLVEKEYYSVGGGFVVNRDGDRVNGVRAAADVPYPFRTGDDLMRACRASGLSIAEL
CCCCEEEEEHHEECCCCEEEECCCCCCCCEEEECCCCCCCCCCHHHHHHHHHCCCEEEEE
TFRNECALRPADEVRAGLVAIWRTMAACVERGCKADGELPGPMRVKRRAAELYTRLRDRS
EECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCC
EESLRDPLSMLDWVNLYAMAVNEENAAGGRVVTAPTNGAAGVIPAVLHYYVKFVPGSNEQ
HHHHHHHHHHHHHHHHEEEEECCCCCCCCEEEECCCCCCCHHHHHHHHHHHEECCCCCCC
GIVDFLLTAAAIGIIYKETASISGAEVGCQGEVGVACSMAAAALAAVMGGTPGQVENAAE
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHH
IGMEHNLGMTCDPVGGLVQIPCIERNAMGAIKALNASRIALKGDGQHYVSLDSVIKTMRE
HCCCCCCCCCCCCCCCEEECCEECCCHHHHHHHCCCCEEEEECCCCEEEEHHHHHHHHHH
TGADMKTKYKETSRGGLAVNVIEC
CCCCHHHHHHHCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]