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The map label for this gene is mlc [C]

Identifier: 126444113

GI number: 126444113

Start: 253071

End: 254321

Strand: Reverse

Name: mlc [C]

Synonym: BURPS668_A0287

Alternate gene names: 126444113

Gene position: 254321-253071 (Counterclockwise)

Preceding gene: 126443393

Following gene: 126445304

Centisome position: 8.13

GC content: 71.94

Gene sequence:

>1251_bases
ATGAGGAGTCCGCACCTCGGCCAGGGCAGCAACTCGGCCAACGTGCGCCGCTACAACGAGCGCCTCCTGCTGAAGACGCT
CAGGCGCGCGGGCAGCGCATCGAAGGCCGATCTGGCCCGGCTCGCCAACCTGACGGGCACCGCGGTCGGCAGCATCATCG
CGTCGCTCGCTGAAGCGAAGCTGATCGAATTCGCCGGCCGCCGCGCCGAAGGCCAGCGTGGCCAGCCCGCATCGCTGATC
CGGCTCGATCCGCGCGGCGCGTTCGGCATCGGCGTGCGGCTCGACCGGATGCGCATCGAGACGGCGCTCGTGAACTTCGC
CGGCGACGTGATCGGCCGCCGCTCGCACGACACGCTGCTGCCGCAGCCGGCCGCCGTGCTCGAGATCGTCCGGGAGGACG
TCGCCGCGATGCAGCAACTGCTTTGCGCGCACGAGCGCGCACGGCTCACGGGCGTCGGCGTCGCGCAGCCGTACAACCTC
GGCAGCTGGCTGCGCGAGATCGACCTGCCCGCCGACGCGTTCGGCGCATGGGCCGAAGTCGATTTCGCGCGCGAGCTCGA
TCGCGCGATCGAGCTGCCCGTCTTCAGCGAAAACGACGGCAACGCGGCCGCGATCGCCGAGCTGTTCTACGGCTGCGGCC
GGCAGCGCGACGATTTCGTCTACCTGTTCCTCGGGCCCGCGATCGGCGGCGGCATCGCGGTGGACGGCGACTGCCTGCGC
GGCGTCACCGGCAACGCCGGCGACTTCGCGATGATGCCGGTGCCGCCGAGCCGGCTGCCCTCGGTGCCGAAGCCGAGCGG
CGCATGGGATCTGCTGATCACGCGCGCGTCGCTGAACGGGCTCGCGCGGCATCTGCGCCACCGCGGCGAAACGCTCGAGA
GCCACGCGGATCTCGAGGCATGCATCGCGCGCGGCGGGCAAGCCGTCGACGAATGGATCGACGATTGCGTCGACGCGCTC
GCACCCGCGCTGCGCGCGGTGCTCGCGGTGCTCGAATCGCCCGTCGTCGTGCTCGATGCGGATACCGACGCGGGCCTGAT
CGACACGCTGATCGCGCGCCTGCACACGGCGCTCGCGGCGCTCGCGCCCGAGGCGCGCGGCACGCCCGTGCTCGTGCGCG
GCACGTTCGGCCCGGACGCTGGCGCGATCGGCGCGGCGACGCTGCCGATGTTCTTCAACTTCTCGCCGCGCGCCGGCATT
CTTCGCGGCGCGGGCGTGGATTCGCAGGAGGCCCGATATGCAGCGTTCTGA

Upstream 100 bases:

>100_bases
GGGAATCCCCTAGGCAGACATGCCGCGCATCTCGCAGTTAAATAAATCAACTTGATTTATTTAACCTCTGGCGTAGCGTG
CCAATTTCGGAGGAGACATC

Downstream 100 bases:

>100_bases
TCCGCCCCGCCCGTTGCTCGAGATGCGCGGCATCAGCAAGACGTTCCCGGCCGTGCGCGCGCTCGCCGGCGTGAGCCTCA
CCGTCCATCCGGGCGAGGTC

Product: transcription regulator ROK family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 416; Mature: 416

Protein sequence:

>416_residues
MRSPHLGQGSNSANVRRYNERLLLKTLRRAGSASKADLARLANLTGTAVGSIIASLAEAKLIEFAGRRAEGQRGQPASLI
RLDPRGAFGIGVRLDRMRIETALVNFAGDVIGRRSHDTLLPQPAAVLEIVREDVAAMQQLLCAHERARLTGVGVAQPYNL
GSWLREIDLPADAFGAWAEVDFARELDRAIELPVFSENDGNAAAIAELFYGCGRQRDDFVYLFLGPAIGGGIAVDGDCLR
GVTGNAGDFAMMPVPPSRLPSVPKPSGAWDLLITRASLNGLARHLRHRGETLESHADLEACIARGGQAVDEWIDDCVDAL
APALRAVLAVLESPVVVLDADTDAGLIDTLIARLHTALAALAPEARGTPVLVRGTFGPDAGAIGAATLPMFFNFSPRAGI
LRGAGVDSQEARYAAF

Sequences:

>Translated_416_residues
MRSPHLGQGSNSANVRRYNERLLLKTLRRAGSASKADLARLANLTGTAVGSIIASLAEAKLIEFAGRRAEGQRGQPASLI
RLDPRGAFGIGVRLDRMRIETALVNFAGDVIGRRSHDTLLPQPAAVLEIVREDVAAMQQLLCAHERARLTGVGVAQPYNL
GSWLREIDLPADAFGAWAEVDFARELDRAIELPVFSENDGNAAAIAELFYGCGRQRDDFVYLFLGPAIGGGIAVDGDCLR
GVTGNAGDFAMMPVPPSRLPSVPKPSGAWDLLITRASLNGLARHLRHRGETLESHADLEACIARGGQAVDEWIDDCVDAL
APALRAVLAVLESPVVVLDADTDAGLIDTLIARLHTALAALAPEARGTPVLVRGTFGPDAGAIGAATLPMFFNFSPRAGI
LRGAGVDSQEARYAAF
>Mature_416_residues
MRSPHLGQGSNSANVRRYNERLLLKTLRRAGSASKADLARLANLTGTAVGSIIASLAEAKLIEFAGRRAEGQRGQPASLI
RLDPRGAFGIGVRLDRMRIETALVNFAGDVIGRRSHDTLLPQPAAVLEIVREDVAAMQQLLCAHERARLTGVGVAQPYNL
GSWLREIDLPADAFGAWAEVDFARELDRAIELPVFSENDGNAAAIAELFYGCGRQRDDFVYLFLGPAIGGGIAVDGDCLR
GVTGNAGDFAMMPVPPSRLPSVPKPSGAWDLLITRASLNGLARHLRHRGETLESHADLEACIARGGQAVDEWIDDCVDAL
APALRAVLAVLESPVVVLDADTDAGLIDTLIARLHTALAALAPEARGTPVLVRGTFGPDAGAIGAATLPMFFNFSPRAGI
LRGAGVDSQEARYAAF

Specific function: May Be A Regulator In Specific Sugar Metabolism. May Influence The Rate Of Glucose Uptake Or Glycolysis In Cells In The Rich Medium. [C]

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family [H]

Homologues:

Organism=Escherichia coli, GI1787878, Length=245, Percent_Identity=20.8163265306122, Blast_Score=69, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000600
- InterPro:   IPR018335
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00480 ROK [H]

EC number: NA

Molecular weight: Translated: 44117; Mature: 44117

Theoretical pI: Translated: 5.95; Mature: 5.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSPHLGQGSNSANVRRYNERLLLKTLRRAGSASKADLARLANLTGTAVGSIIASLAEAK
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LIEFAGRRAEGQRGQPASLIRLDPRGAFGIGVRLDRMRIETALVNFAGDVIGRRSHDTLL
HHHHHCCCCCCCCCCCCCEEEECCCCCEEECEEEHHHHHHHHHHHHHHHHHCCCCCCCCC
PQPAAVLEIVREDVAAMQQLLCAHERARLTGVGVAQPYNLGSWLREIDLPADAFGAWAEV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCHHHHHHHHCCCHHHHCCHHHH
DFARELDRAIELPVFSENDGNAAAIAELFYGCGRQRDDFVYLFLGPAIGGGIAVDGDCLR
HHHHHHHHHHCCCEEECCCCCHHHHHHHHHHCCCCCCCEEEEEECCCCCCCEEECCHHHC
GVTGNAGDFAMMPVPPSRLPSVPKPSGAWDLLITRASLNGLARHLRHRGETLESHADLEA
CCCCCCCCEEEECCCHHHCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHCHHHHHHHHHHH
CIARGGQAVDEWIDDCVDALAPALRAVLAVLESPVVVLDADTDAGLIDTLIARLHTALAA
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHH
LAPEARGTPVLVRGTFGPDAGAIGAATLPMFFNFSPRAGILRGAGVDSQEARYAAF
HCCCCCCCEEEEEECCCCCCCCCCHHHHHHEECCCCCCCCEECCCCCCCCCHHCCC
>Mature Secondary Structure
MRSPHLGQGSNSANVRRYNERLLLKTLRRAGSASKADLARLANLTGTAVGSIIASLAEAK
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LIEFAGRRAEGQRGQPASLIRLDPRGAFGIGVRLDRMRIETALVNFAGDVIGRRSHDTLL
HHHHHCCCCCCCCCCCCCEEEECCCCCEEECEEEHHHHHHHHHHHHHHHHHCCCCCCCCC
PQPAAVLEIVREDVAAMQQLLCAHERARLTGVGVAQPYNLGSWLREIDLPADAFGAWAEV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCHHHHHHHHCCCHHHHCCHHHH
DFARELDRAIELPVFSENDGNAAAIAELFYGCGRQRDDFVYLFLGPAIGGGIAVDGDCLR
HHHHHHHHHHCCCEEECCCCCHHHHHHHHHHCCCCCCCEEEEEECCCCCCCEEECCHHHC
GVTGNAGDFAMMPVPPSRLPSVPKPSGAWDLLITRASLNGLARHLRHRGETLESHADLEA
CCCCCCCCEEEECCCHHHCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHCHHHHHHHHHHH
CIARGGQAVDEWIDDCVDALAPALRAVLAVLESPVVVLDADTDAGLIDTLIARLHTALAA
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHH
LAPEARGTPVLVRGTFGPDAGAIGAATLPMFFNFSPRAGILRGAGVDSQEARYAAF
HCCCCCCCEEEEEECCCCCCCCCCHHHHHHEECCCCCCCCEECCCCCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]