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The map label for this gene is exuT [H]

Identifier: 126443961

GI number: 126443961

Start: 2030844

End: 2032184

Strand: Reverse

Name: exuT [H]

Synonym: BURPS668_A2092

Alternate gene names: 126443961

Gene position: 2032184-2030844 (Counterclockwise)

Preceding gene: 126444142

Following gene: 126444910

Centisome position: 64.98

GC content: 69.57

Gene sequence:

>1341_bases
ATGCATCAGAGAACGATGGGGTGGGTCACGGTATTCCTGCTGTTCGTCGTGTACGGCATCAATTATCTCGACCGCGTCGC
GCTGTCGATCGTCGCGCCGATGGTGCGGCGGGATCTCGGGATCGACGCCGCGCAGATGGGCATCGTCTTCAGCACGTTCT
TCGTCGGCTATGCGCTGTTCAACTTCATCGGCGGTCTCGCGTCGGACCGGCTCGGGCCGAAGCGCGTCTATGTGATCGCC
GTGGGCCTCTGGTCGATCTTCTGCGGGATGACGGCGATCACGGTCGGCTTCGTCAGCCTGCTGATCGTGCGCCTGCTGTT
CGGCATGGCCGAGGGGCCGCTCTGCTCGGCCGCGAACAAGATGGTCAACAACTGGCTGCCGCGCGAATCGGCGGCCACGG
CGATGGGGCTGCTGAGCGCCGGCTCGCCGCTCGGCGGCGCGCTCGCCGGGCCGATCGTCGGGGTGCTCGCCGCGCAGCTC
GGCTGGCGGCCGGCGTTCTGGATCGTGTGTGCGATCGGCCTCGCGTGGGTGCTCGTGTGGATCGCGACGACGTCGGACCG
GCCCGCGCCGCAGGCGTCGGCGATGCCGGCTGGCGGCTCGGGCGCCGCCGCCGCGGCGGCGCGCGCTGCGGCGGCGCCGC
GCGCGTGCGCCAGCGGCGGCCGCACCGCCGATGCCGCCCATGCCTCCGATGCCGCCGACGTGCCGCCGCTGCGCGATTAC
CTGAAGCAGCCGCGCATACTGGCGACGGGCGTCGCGTTCTTCGGCTACAACTACGTGCTGTTCTTCTTCCTGAGCTGGTT
TCCGAGCTATCTCGTGCAGGCGCATCACCTGAACATCCGCGAGATGAGCGTCGCGACGGTCGTGCCGTGGCTCGTCGGCA
CGATCGGTCTCGCGTGCGGCGGCGTGATCTCGGACGGAATCTACAAGCTCACCGGCAACGCGATGCTGTCGCGCCGGATC
GTGCTCGTCGGGTGCCTGCTCGGCGCGGGGGTCTGCGTCGCGATCGCGGGCTCGGTGCGCTCGACGCAGAGCGCGATCGC
GCTGATGTCGGTATCGCTCTTTTTCCTTTACGCGACGGGCGCGATCTACTGGGCGATCGTTCAGGACATCGTCGCGCCGG
GGCGCGTCGGCGCGGTCAGCGGCTGCCTGCACTGCATGGGAAGCCTGTCGGGCGTCATCGGGCCCGCCGTCACCGGATTC
ATCGTCGAGCGCAGCGGCTCGTTCGTGTCCGCGTTCGTGCTTGCCGGCGCGATCGCGCTCGCGGGCGCGGTGCTGTCCGC
GCTCTTCCTGCGCAACCGTGCGTGCGATGCGCGTGTGCTGCGCGAAAGTCCGCTTCTGTAG

Upstream 100 bases:

>100_bases
TTCGCCGCGCGAGCCGGATCACGTTCGATCCGCGCCGCGTCCGCGAGCGGCGGCGGCCCAACACATGAACGCCGGAGACA
TCGGCATGAAGGAGACAGGC

Downstream 100 bases:

>100_bases
GCGTGGGTGCGAGGCGTGCGGCTTGGGCGCGAATGCGGGCGGCGGCTGGATGCCGAGCAGGCCGCCCGCGCACGCGCCGT
CGCCGACGAGCGCGGTGCGG

Product: membrane transport protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 446; Mature: 446

Protein sequence:

>446_residues
MHQRTMGWVTVFLLFVVYGINYLDRVALSIVAPMVRRDLGIDAAQMGIVFSTFFVGYALFNFIGGLASDRLGPKRVYVIA
VGLWSIFCGMTAITVGFVSLLIVRLLFGMAEGPLCSAANKMVNNWLPRESAATAMGLLSAGSPLGGALAGPIVGVLAAQL
GWRPAFWIVCAIGLAWVLVWIATTSDRPAPQASAMPAGGSGAAAAAARAAAAPRACASGGRTADAAHASDAADVPPLRDY
LKQPRILATGVAFFGYNYVLFFFLSWFPSYLVQAHHLNIREMSVATVVPWLVGTIGLACGGVISDGIYKLTGNAMLSRRI
VLVGCLLGAGVCVAIAGSVRSTQSAIALMSVSLFFLYATGAIYWAIVQDIVAPGRVGAVSGCLHCMGSLSGVIGPAVTGF
IVERSGSFVSAFVLAGAIALAGAVLSALFLRNRACDARVLRESPLL

Sequences:

>Translated_446_residues
MHQRTMGWVTVFLLFVVYGINYLDRVALSIVAPMVRRDLGIDAAQMGIVFSTFFVGYALFNFIGGLASDRLGPKRVYVIA
VGLWSIFCGMTAITVGFVSLLIVRLLFGMAEGPLCSAANKMVNNWLPRESAATAMGLLSAGSPLGGALAGPIVGVLAAQL
GWRPAFWIVCAIGLAWVLVWIATTSDRPAPQASAMPAGGSGAAAAAARAAAAPRACASGGRTADAAHASDAADVPPLRDY
LKQPRILATGVAFFGYNYVLFFFLSWFPSYLVQAHHLNIREMSVATVVPWLVGTIGLACGGVISDGIYKLTGNAMLSRRI
VLVGCLLGAGVCVAIAGSVRSTQSAIALMSVSLFFLYATGAIYWAIVQDIVAPGRVGAVSGCLHCMGSLSGVIGPAVTGF
IVERSGSFVSAFVLAGAIALAGAVLSALFLRNRACDARVLRESPLL
>Mature_446_residues
MHQRTMGWVTVFLLFVVYGINYLDRVALSIVAPMVRRDLGIDAAQMGIVFSTFFVGYALFNFIGGLASDRLGPKRVYVIA
VGLWSIFCGMTAITVGFVSLLIVRLLFGMAEGPLCSAANKMVNNWLPRESAATAMGLLSAGSPLGGALAGPIVGVLAAQL
GWRPAFWIVCAIGLAWVLVWIATTSDRPAPQASAMPAGGSGAAAAAARAAAAPRACASGGRTADAAHASDAADVPPLRDY
LKQPRILATGVAFFGYNYVLFFFLSWFPSYLVQAHHLNIREMSVATVVPWLVGTIGLACGGVISDGIYKLTGNAMLSRRI
VLVGCLLGAGVCVAIAGSVRSTQSAIALMSVSLFFLYATGAIYWAIVQDIVAPGRVGAVSGCLHCMGSLSGVIGPAVTGF
IVERSGSFVSAFVLAGAIALAGAVLSALFLRNRACDARVLRESPLL

Specific function: Aldohexuronate transport system [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI6912666, Length=404, Percent_Identity=22.029702970297, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI154350196, Length=429, Percent_Identity=23.0769230769231, Blast_Score=92, Evalue=8e-19,
Organism=Homo sapiens, GI9966811, Length=397, Percent_Identity=23.4256926952141, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI21322234, Length=413, Percent_Identity=23.0024213075061, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI9945322, Length=397, Percent_Identity=22.4181360201511, Blast_Score=79, Evalue=8e-15,
Organism=Homo sapiens, GI4885441, Length=406, Percent_Identity=22.4137931034483, Blast_Score=76, Evalue=5e-14,
Organism=Homo sapiens, GI223718438, Length=213, Percent_Identity=26.2910798122066, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI1789152, Length=445, Percent_Identity=29.8876404494382, Blast_Score=177, Evalue=9e-46,
Organism=Escherichia coli, GI2367379, Length=428, Percent_Identity=24.5327102803738, Blast_Score=168, Evalue=7e-43,
Organism=Escherichia coli, GI1789515, Length=440, Percent_Identity=27.9545454545455, Blast_Score=168, Evalue=7e-43,
Organism=Escherichia coli, GI87082320, Length=419, Percent_Identity=26.7303102625298, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI2367193, Length=417, Percent_Identity=22.3021582733813, Blast_Score=85, Evalue=8e-18,
Organism=Escherichia coli, GI87081723, Length=191, Percent_Identity=29.8429319371728, Blast_Score=62, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17552542, Length=401, Percent_Identity=24.4389027431421, Blast_Score=96, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17535049, Length=424, Percent_Identity=23.1132075471698, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI193205400, Length=281, Percent_Identity=23.4875444839858, Blast_Score=86, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI115533554, Length=364, Percent_Identity=21.4285714285714, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI115533556, Length=364, Percent_Identity=21.4285714285714, Blast_Score=83, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI71991448, Length=381, Percent_Identity=22.8346456692913, Blast_Score=80, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI71991453, Length=381, Percent_Identity=22.8346456692913, Blast_Score=79, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI32565914, Length=259, Percent_Identity=23.9382239382239, Blast_Score=78, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI32565916, Length=259, Percent_Identity=23.9382239382239, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24641682, Length=428, Percent_Identity=23.3644859813084, Blast_Score=92, Evalue=8e-19,
Organism=Drosophila melanogaster, GI24648416, Length=402, Percent_Identity=21.8905472636816, Blast_Score=92, Evalue=1e-18,
Organism=Drosophila melanogaster, GI21356189, Length=402, Percent_Identity=21.8905472636816, Blast_Score=92, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24639764, Length=377, Percent_Identity=22.2811671087533, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI19920686, Length=423, Percent_Identity=25.0591016548463, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI28573299, Length=452, Percent_Identity=22.1238938053097, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24584153, Length=369, Percent_Identity=19.5121951219512, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI45550460, Length=447, Percent_Identity=20.5816554809843, Blast_Score=70, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24580790, Length=363, Percent_Identity=20.6611570247934, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24655255, Length=429, Percent_Identity=20.5128205128205, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI20129235, Length=401, Percent_Identity=23.6907730673317, Blast_Score=65, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 46443; Mature: 46443

Theoretical pI: Translated: 9.44; Mature: 9.44

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHCCCHHHHHHCCCCC
>Mature Secondary Structure
MHQRTMGWVTVFLLFVVYGINYLDRVALSIVAPMVRRDLGIDAAQMGIVFSTFFVGYALF
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
NFIGGLASDRLGPKRVYVIAVGLWSIFCGMTAITVGFVSLLIVRLLFGMAEGPLCSAANK
HHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
MVNNWLPRESAATAMGLLSAGSPLGGALAGPIVGVLAAQLGWRPAFWIVCAIGLAWVLVW
HHHHCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
IATTSDRPAPQASAMPAGGSGAAAAAARAAAAPRACASGGRTADAAHASDAADVPPLRDY
HHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHCCCCCCCCCCCCCCCCCCHHHHH
LKQPRILATGVAFFGYNYVLFFFLSWFPSYLVQAHHLNIREMSVATVVPWLVGTIGLACG
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
GVISDGIYKLTGNAMLSRRIVLVGCLLGAGVCVAIAGSVRSTQSAIALMSVSLFFLYATG
HHHHCCHHEECCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
AIYWAIVQDIVAPGRVGAVSGCLHCMGSLSGVIGPAVTGFIVERSGSFVSAFVLAGAIAL
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
AGAVLSALFLRNRACDARVLRESPLL
HHHHHHHHHHHHCCCHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579062; 9384377 [H]