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The map label for this gene is sufS [C]

Identifier: 126443732

GI number: 126443732

Start: 1850978

End: 1852960

Strand: Reverse

Name: sufS [C]

Synonym: BURPS668_A1904

Alternate gene names: 126443732

Gene position: 1852960-1850978 (Counterclockwise)

Preceding gene: 126444458

Following gene: 126443736

Centisome position: 59.25

GC content: 71.41

Gene sequence:

>1983_bases
ATGAGTGCCGCACCCGTCGCGCTGCCGGACGCGGCGCCGCCCGCCGGGCTGCCCGATCCGGCGACGCTTGCGCGCCTTGC
GTCGGAGTTTCTCGCCGCGCTGCCCGGGCAGCCCGCCGCGCCGAATGCCGGCGCGGGCAGCGGCGCCGTCGGCGGTGTGC
CGTCGGCGTTGCCGGCCGCCGCGCCGATGCTTGCGTCGGTTTCGAATCCCGCGCCGCCGGGCTCGCCGCTTGCCGGGCCG
GGCGGCACCGGCACGGGCGTGCCGGGCATCGGGGCGCCGCCGGGCAAGGTGCCCGGCGCGAACCTCGTACCCGCGCCGAC
ACATGTGCTGTCGCTCGGCAATCGCACGCCCGCGCTCGTTGGGCACGCGGCCGCGCAAAACGGATGGCCGGACAGCGCGG
TTGCGATCGCGCCGGCGCTCGAGCCGCGCGCGGGCGGCGTCGCGCTCGGCGTGCCGCCCGTGCCGGAACCCGATGCCGTC
CGTCGCGCGGGCGATGCGTCCGCGGCGGCGGCGCCTTCGCCTTGGTCGTATTACTTTGTCGAGCCCGCCTCGGATGATTG
GTGGCGCGACGCCGCGCGCACGCCGATCGACGTGCCGCGCGACGGCGTCGCGTCGCCGCGCGCGTTCGGCCTGCCCGACG
AAAACGCGTGGCGCGATCTGCTGTCGATCGGACGGCCGGCCGCCGATCGGCATCGCGCGTCGCGCTATTTCGTCGACGAC
GCGCAGCCCACGAATGCGCATGCGCCTGGCGCCGGCGCGCATCCGCCGTTCGACGTCGCCGCGATTCGCCGCGATTTCCC
GATACTCGCCGAGCGGGTGAACGGCAAGCCGCTCGTCTGGTTCGACAACGCGGCGACGACGCACAAGCCGCAGGCGGTGA
TCGATCGTCTCGCGCACTTCTATGCACACGAGAATTCGAACATCCATCGCGCGGCGCATGCGCTCGCCGCGCGCGCGACC
GACGCGTACGAGCACGCGCGCGCGACCGTGCAGCGCTTCATCGGCGCGGCGTCGCCGGACGAGATCGTGTTCGTGCGCGG
CGCGACGGAGGCGATCAATCTGATCGCGAAAACATGGGGTGTCGGCAACGTCGGGGAAGGCGACGAGATCGTCGTGTCGC
ATCTCGAGCATCACGCGAACATCGTGCCGTGGCAGCAGCTCGCCGCGTCGGTGGGCGCCGCGCTGCGCGTGATTCCCGTC
GACGATGCCGGCCAGGTCTTGCTCGGCGAGTACCGGAAGCTGCTCAACGATCGCACGAAGATCGTCTCCGTCACGCAGGT
ATCGAACGCGCTCGGCACGGTCGTGCCGGTGAAGGAGATCGTCGAGCTCGCGCATCGCGCGGGCGCGAAGGTGCTCGTCG
ACGGCGCACAGTCGATTTCGCACATGCGCGTCGACGTGCAGGCGCTCGACGCCGATTTCTTCGTGTTCTCCGGCCACAAG
ATCTACGGCCCGACGGGAATCGGCGTCGTCTATGGCAAGCGCGCGCTGCTCGACGGCATGCCGCCGTGGCAAGGCGGCGG
CAACATGATCGCGGACGTGACGTTCGAGCGCACCGTATTCCAGCCGCCGCCGAACCGTTTCGAGGCGGGAACGGGCAACA
TCGCCGATGCGGTCGGGCTCGGTGCAGCGCTCGATTACGTGGCGCGGATCGGCATCGAGCGGATCGCGCGCTACGAGCAC
GATCTGCTCGCCTATGCGGCGGGCGTGCTCGCGCCGGTGCCGGGTGTGCGGCTGATCGGCACCGCGCGCGATAAGGCGAG
CGTGCTGTCGTTCGTGCTGAAGGGCTATGAGACGGAAGAAGTCGGGCGAGCGCTGAATGCGGCCGGCATCGCCGTGCGGT
CCGGGCACCACTGCGCGCAGCCGATTCTGCGCCGCTTCGGGCTCGAAGCGACCGTGCGTGCGTCGCTCGCGTTCTACAAC
ACGCGCGACGAGGTCGATGCGATGGTCGACGTCGTGCGCGAGCTTGCGGCGCGGCGCATCTAG

Upstream 100 bases:

>100_bases
TGCTCGCTTGCCGTCCACTCGCCGGATGCGCTGGCTGTCCTCGATGACGTGGAGATCGGCAAGTACCATGACTATCCCGA
CACCTACCGTTGATTCCGCC

Downstream 100 bases:

>100_bases
CGGCGGCGCGCGGCCGGGCGGCGCCGGTTCGGCCGATTCGCCCCGTTCGAACGGGGCGACCGCCGCGCCGCCGAATGCCG
GACGGCCGGACGCCGATGCG

Product: cysteine desulphurases, SufS

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 660; Mature: 659

Protein sequence:

>660_residues
MSAAPVALPDAAPPAGLPDPATLARLASEFLAALPGQPAAPNAGAGSGAVGGVPSALPAAAPMLASVSNPAPPGSPLAGP
GGTGTGVPGIGAPPGKVPGANLVPAPTHVLSLGNRTPALVGHAAAQNGWPDSAVAIAPALEPRAGGVALGVPPVPEPDAV
RRAGDASAAAAPSPWSYYFVEPASDDWWRDAARTPIDVPRDGVASPRAFGLPDENAWRDLLSIGRPAADRHRASRYFVDD
AQPTNAHAPGAGAHPPFDVAAIRRDFPILAERVNGKPLVWFDNAATTHKPQAVIDRLAHFYAHENSNIHRAAHALAARAT
DAYEHARATVQRFIGAASPDEIVFVRGATEAINLIAKTWGVGNVGEGDEIVVSHLEHHANIVPWQQLAASVGAALRVIPV
DDAGQVLLGEYRKLLNDRTKIVSVTQVSNALGTVVPVKEIVELAHRAGAKVLVDGAQSISHMRVDVQALDADFFVFSGHK
IYGPTGIGVVYGKRALLDGMPPWQGGGNMIADVTFERTVFQPPPNRFEAGTGNIADAVGLGAALDYVARIGIERIARYEH
DLLAYAAGVLAPVPGVRLIGTARDKASVLSFVLKGYETEEVGRALNAAGIAVRSGHHCAQPILRRFGLEATVRASLAFYN
TRDEVDAMVDVVRELAARRI

Sequences:

>Translated_660_residues
MSAAPVALPDAAPPAGLPDPATLARLASEFLAALPGQPAAPNAGAGSGAVGGVPSALPAAAPMLASVSNPAPPGSPLAGP
GGTGTGVPGIGAPPGKVPGANLVPAPTHVLSLGNRTPALVGHAAAQNGWPDSAVAIAPALEPRAGGVALGVPPVPEPDAV
RRAGDASAAAAPSPWSYYFVEPASDDWWRDAARTPIDVPRDGVASPRAFGLPDENAWRDLLSIGRPAADRHRASRYFVDD
AQPTNAHAPGAGAHPPFDVAAIRRDFPILAERVNGKPLVWFDNAATTHKPQAVIDRLAHFYAHENSNIHRAAHALAARAT
DAYEHARATVQRFIGAASPDEIVFVRGATEAINLIAKTWGVGNVGEGDEIVVSHLEHHANIVPWQQLAASVGAALRVIPV
DDAGQVLLGEYRKLLNDRTKIVSVTQVSNALGTVVPVKEIVELAHRAGAKVLVDGAQSISHMRVDVQALDADFFVFSGHK
IYGPTGIGVVYGKRALLDGMPPWQGGGNMIADVTFERTVFQPPPNRFEAGTGNIADAVGLGAALDYVARIGIERIARYEH
DLLAYAAGVLAPVPGVRLIGTARDKASVLSFVLKGYETEEVGRALNAAGIAVRSGHHCAQPILRRFGLEATVRASLAFYN
TRDEVDAMVDVVRELAARRI
>Mature_659_residues
SAAPVALPDAAPPAGLPDPATLARLASEFLAALPGQPAAPNAGAGSGAVGGVPSALPAAAPMLASVSNPAPPGSPLAGPG
GTGTGVPGIGAPPGKVPGANLVPAPTHVLSLGNRTPALVGHAAAQNGWPDSAVAIAPALEPRAGGVALGVPPVPEPDAVR
RAGDASAAAAPSPWSYYFVEPASDDWWRDAARTPIDVPRDGVASPRAFGLPDENAWRDLLSIGRPAADRHRASRYFVDDA
QPTNAHAPGAGAHPPFDVAAIRRDFPILAERVNGKPLVWFDNAATTHKPQAVIDRLAHFYAHENSNIHRAAHALAARATD
AYEHARATVQRFIGAASPDEIVFVRGATEAINLIAKTWGVGNVGEGDEIVVSHLEHHANIVPWQQLAASVGAALRVIPVD
DAGQVLLGEYRKLLNDRTKIVSVTQVSNALGTVVPVKEIVELAHRAGAKVLVDGAQSISHMRVDVQALDADFFVFSGHKI
YGPTGIGVVYGKRALLDGMPPWQGGGNMIADVTFERTVFQPPPNRFEAGTGNIADAVGLGAALDYVARIGIERIARYEHD
LLAYAAGVLAPVPGVRLIGTARDKASVLSFVLKGYETEEVGRALNAAGIAVRSGHHCAQPILRRFGLEATVRASLAFYNT
RDEVDAMVDVVRELAARRI

Specific function: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine [H]

COG id: COG0520

COG function: function code E; Selenocysteine lyase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily [H]

Homologues:

Organism=Homo sapiens, GI32307132, Length=391, Percent_Identity=27.3657289002558, Blast_Score=110, Evalue=4e-24,
Organism=Homo sapiens, GI156713448, Length=389, Percent_Identity=26.4781491002571, Blast_Score=83, Evalue=6e-16,
Organism=Escherichia coli, GI1787970, Length=394, Percent_Identity=51.5228426395939, Blast_Score=411, Evalue=1e-116,
Organism=Escherichia coli, GI1789175, Length=396, Percent_Identity=40.6565656565657, Blast_Score=293, Evalue=2e-80,
Organism=Escherichia coli, GI48994898, Length=398, Percent_Identity=28.391959798995, Blast_Score=113, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI25143064, Length=391, Percent_Identity=26.3427109974425, Blast_Score=104, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI193211090, Length=344, Percent_Identity=24.4186046511628, Blast_Score=81, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6319831, Length=229, Percent_Identity=31.0043668122271, Blast_Score=114, Evalue=5e-26,
Organism=Drosophila melanogaster, GI20129463, Length=429, Percent_Identity=27.972027972028, Blast_Score=114, Evalue=3e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR010970
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.8.1.7 [H]

Molecular weight: Translated: 68623; Mature: 68492

Theoretical pI: Translated: 6.77; Mature: 6.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAAPVALPDAAPPAGLPDPATLARLASEFLAALPGQPAAPNAGAGSGAVGGVPSALPAA
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHH
APMLASVSNPAPPGSPLAGPGGTGTGVPGIGAPPGKVPGANLVPAPTHVLSLGNRTPALV
HHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCHHH
GHAAAQNGWPDSAVAIAPALEPRAGGVALGVPPVPEPDAVRRAGDASAAAAPSPWSYYFV
HHHHHCCCCCCCCEEEECCCCCCCCCEEECCCCCCCCHHHHHCCCCCCCCCCCCCEEEEE
EPASDDWWRDAARTPIDVPRDGVASPRAFGLPDENAWRDLLSIGRPAADRHRASRYFVDD
ECCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHCCEEECC
AQPTNAHAPGAGAHPPFDVAAIRRDFPILAERVNGKPLVWFDNAATTHKPQAVIDRLAHF
CCCCCCCCCCCCCCCCHHHHHHHHCCHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHH
YAHENSNIHRAAHALAARATDAYEHARATVQRFIGAASPDEIVFVRGATEAINLIAKTWG
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHCC
VGNVGEGDEIVVSHLEHHANIVPWQQLAASVGAALRVIPVDDAGQVLLGEYRKLLNDRTK
CCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHCCEEEEEECCCCCHHHHHHHHHHHCCHHH
IVSVTQVSNALGTVVPVKEIVELAHRAGAKVLVDGAQSISHMRVDVQALDADFFVFSGHK
EEEHHHHHHHHHHHCCHHHHHHHHHHCCCEEEEECHHHHHHHEEEEEEECCCEEEEECCE
IYGPTGIGVVYGKRALLDGMPPWQGGGNMIADVTFERTVFQPPPNRFEAGTGNIADAVGL
EECCCCCHHHHCCHHHHCCCCCCCCCCCEEEEEEEECEECCCCCCCCCCCCCCHHHHHHH
GAALDYVARIGIERIARYEHDLLAYAAGVLAPVPGVRLIGTARDKASVLSFVLKGYETEE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHCCCHHH
VGRALNAAGIAVRSGHHCAQPILRRFGLEATVRASLAFYNTRDEVDAMVDVVRELAARRI
HHHHHHHCCEEEECCCHHHHHHHHHHCCCCEEHHHHHCCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SAAPVALPDAAPPAGLPDPATLARLASEFLAALPGQPAAPNAGAGSGAVGGVPSALPAA
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHH
APMLASVSNPAPPGSPLAGPGGTGTGVPGIGAPPGKVPGANLVPAPTHVLSLGNRTPALV
HHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCHHH
GHAAAQNGWPDSAVAIAPALEPRAGGVALGVPPVPEPDAVRRAGDASAAAAPSPWSYYFV
HHHHHCCCCCCCCEEEECCCCCCCCCEEECCCCCCCCHHHHHCCCCCCCCCCCCCEEEEE
EPASDDWWRDAARTPIDVPRDGVASPRAFGLPDENAWRDLLSIGRPAADRHRASRYFVDD
ECCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHCCEEECC
AQPTNAHAPGAGAHPPFDVAAIRRDFPILAERVNGKPLVWFDNAATTHKPQAVIDRLAHF
CCCCCCCCCCCCCCCCHHHHHHHHCCHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHH
YAHENSNIHRAAHALAARATDAYEHARATVQRFIGAASPDEIVFVRGATEAINLIAKTWG
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHCC
VGNVGEGDEIVVSHLEHHANIVPWQQLAASVGAALRVIPVDDAGQVLLGEYRKLLNDRTK
CCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHCCEEEEEECCCCCHHHHHHHHHHHCCHHH
IVSVTQVSNALGTVVPVKEIVELAHRAGAKVLVDGAQSISHMRVDVQALDADFFVFSGHK
EEEHHHHHHHHHHHCCHHHHHHHHHHCCCEEEEECHHHHHHHEEEEEEECCCEEEEECCE
IYGPTGIGVVYGKRALLDGMPPWQGGGNMIADVTFERTVFQPPPNRFEAGTGNIADAVGL
EECCCCCHHHHCCHHHHCCCCCCCCCCCEEEEEEEECEECCCCCCCCCCCCCCHHHHHHH
GAALDYVARIGIERIARYEHDLLAYAAGVLAPVPGVRLIGTARDKASVLSFVLKGYETEE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHCCCHHH
VGRALNAAGIAVRSGHHCAQPILRRFGLEATVRASLAFYNTRDEVDAMVDVVRELAARRI
HHHHHHHCCEEEECCCHHHHHHHHHHCCCCEEHHHHHCCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA