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The map label for this gene is yncB [H]

Identifier: 126443573

GI number: 126443573

Start: 1724836

End: 1725873

Strand: Reverse

Name: yncB [H]

Synonym: BURPS668_A1778

Alternate gene names: 126443573

Gene position: 1725873-1724836 (Counterclockwise)

Preceding gene: 126444714

Following gene: 126442879

Centisome position: 55.18

GC content: 69.56

Gene sequence:

>1038_bases
ATGCCGCAAACCAAGACGACCAACCGCAGGATCGTGCTGCACTCGCGCCCGAAGGGCGCGCCCACGCCGGAGAATTTCCG
CACCGAAACGGCGGCGGTGCCCGTGCCCGCGCCGGGCGAGGTGCTGCTGCGCACGATCTGGCTGTCGCTCGATCCGTACA
TGCGCGGCCGCATGAACGACGCGCCCTCGTATGCTGCGCCCGTCTGGCTCGGCGGCGTGATGGTGGGCGGGACGGTGAGC
CGCGTCGTCTCGTCGAGCGTGCCCGCGTTCCGCGACGGCGATCTCGTGCTGTCGAACGCCGGCTGGCAGGACTACGCCGT
GTCCGACGGCACCGACCTGATGCCGCTCGCGGACGTCGCGCATCCGTCGTACGCGCTCGGCGTGCTCGGCATGCCGGGCT
TCACCGCATACTTCGGATTGCTGCATATCGGCGAGCCGAAGGCGGGCGAGACGGTGGCCGTCGCGGCGGCGAGCGGCGCG
GTGGGCGCGGTCGTCGGGCAGATCGCGAAGCTCAAGGGTTGCCGCGTCGTCGGCATCGCGGGCGGCGCGGACAAGTGCCG
CTATGTGGCCGGGACGCTCGGCTTCGACGCGTGCGTCGATCACCACGATCCCGATTTCGCGAAACAGCTCGCCGCCGCGT
GCCCGGACGGCATCGACGTGTATTTCGAGAACGTCGGCGGCGCGGTGTTCGACGCGGTGCTGCCGCTGCTGAACGATCAT
GCGCGCGTGCCGGTGTGCGGGCTGATCGCCCACTACAACGACAGCGAGCTGCCGGGTGGCCCGAACCGCCTGCCGCTGCT
CACGTCGAGCGTGCTGCGCAAGCGGATCAGGATGCAGGGCTTCATCATCCTCGATCACTACGCGAACGTTTATCCGGCCT
TCCTGAAGGACATGAGCGAATGGGTCGCGCAAGGCAAGGTGAAGCCGCGCGAGGACGTCGTCGACGGGCTCGACGCGGCG
CCGCGGGCGCTGATCGGCCTGCTCGGCGGGAAGAACTTCGGCAAGGTGGTCGTGCGCGTGGGGCCCGACACGCTCTAA

Upstream 100 bases:

>100_bases
GACGTGAGCCGCCGCGTGCTCGAGGCCAGCCTGTGAGCGCGCCGCGCTTCGCCCCGTTCGCCGCACCCTGACGACGCCTT
CCATTCCGACGGAGAAAGCC

Downstream 100 bases:

>100_bases
GTTCGCCGCGCGCGCGTGCGGGCGAATCCATGTGTGCGCAGGCATGCGCGGCCCGTGCGGCACGCGTCGCTTCGTGCGCG
GGCGGCAGGTGTCGAATCGA

Product: putative NADP-dependent oxidoreductase yncb

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 345; Mature: 344

Protein sequence:

>345_residues
MPQTKTTNRRIVLHSRPKGAPTPENFRTETAAVPVPAPGEVLLRTIWLSLDPYMRGRMNDAPSYAAPVWLGGVMVGGTVS
RVVSSSVPAFRDGDLVLSNAGWQDYAVSDGTDLMPLADVAHPSYALGVLGMPGFTAYFGLLHIGEPKAGETVAVAAASGA
VGAVVGQIAKLKGCRVVGIAGGADKCRYVAGTLGFDACVDHHDPDFAKQLAAACPDGIDVYFENVGGAVFDAVLPLLNDH
ARVPVCGLIAHYNDSELPGGPNRLPLLTSSVLRKRIRMQGFIILDHYANVYPAFLKDMSEWVAQGKVKPREDVVDGLDAA
PRALIGLLGGKNFGKVVVRVGPDTL

Sequences:

>Translated_345_residues
MPQTKTTNRRIVLHSRPKGAPTPENFRTETAAVPVPAPGEVLLRTIWLSLDPYMRGRMNDAPSYAAPVWLGGVMVGGTVS
RVVSSSVPAFRDGDLVLSNAGWQDYAVSDGTDLMPLADVAHPSYALGVLGMPGFTAYFGLLHIGEPKAGETVAVAAASGA
VGAVVGQIAKLKGCRVVGIAGGADKCRYVAGTLGFDACVDHHDPDFAKQLAAACPDGIDVYFENVGGAVFDAVLPLLNDH
ARVPVCGLIAHYNDSELPGGPNRLPLLTSSVLRKRIRMQGFIILDHYANVYPAFLKDMSEWVAQGKVKPREDVVDGLDAA
PRALIGLLGGKNFGKVVVRVGPDTL
>Mature_344_residues
PQTKTTNRRIVLHSRPKGAPTPENFRTETAAVPVPAPGEVLLRTIWLSLDPYMRGRMNDAPSYAAPVWLGGVMVGGTVSR
VVSSSVPAFRDGDLVLSNAGWQDYAVSDGTDLMPLADVAHPSYALGVLGMPGFTAYFGLLHIGEPKAGETVAVAAASGAV
GAVVGQIAKLKGCRVVGIAGGADKCRYVAGTLGFDACVDHHDPDFAKQLAAACPDGIDVYFENVGGAVFDAVLPLLNDHA
RVPVCGLIAHYNDSELPGGPNRLPLLTSSVLRKRIRMQGFIILDHYANVYPAFLKDMSEWVAQGKVKPREDVVDGLDAAP
RALIGLLGGKNFGKVVVRVGPDTL

Specific function: Unknown

COG id: COG2130

COG function: function code R; Putative NADP-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NADP-dependent oxidoreductase L4BD family [H]

Homologues:

Organism=Homo sapiens, GI226059159, Length=347, Percent_Identity=38.6167146974063, Blast_Score=231, Evalue=6e-61,
Organism=Homo sapiens, GI226059133, Length=347, Percent_Identity=38.6167146974063, Blast_Score=231, Evalue=6e-61,
Organism=Homo sapiens, GI226246682, Length=347, Percent_Identity=37.1757925072046, Blast_Score=224, Evalue=1e-58,
Organism=Homo sapiens, GI226246680, Length=347, Percent_Identity=37.1757925072046, Blast_Score=224, Evalue=1e-58,
Organism=Homo sapiens, GI22748929, Length=347, Percent_Identity=37.1757925072046, Blast_Score=224, Evalue=1e-58,
Organism=Homo sapiens, GI226056130, Length=320, Percent_Identity=38.75, Blast_Score=203, Evalue=2e-52,
Organism=Homo sapiens, GI28557745, Length=337, Percent_Identity=29.080118694362, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI194239674, Length=239, Percent_Identity=28.8702928870293, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI13236495, Length=239, Percent_Identity=28.8702928870293, Blast_Score=74, Evalue=3e-13,
Organism=Escherichia coli, GI226510941, Length=344, Percent_Identity=64.2441860465116, Blast_Score=456, Evalue=1e-129,
Organism=Caenorhabditis elegans, GI133901710, Length=358, Percent_Identity=33.5195530726257, Blast_Score=187, Evalue=6e-48,
Organism=Caenorhabditis elegans, GI133901712, Length=358, Percent_Identity=33.5195530726257, Blast_Score=187, Evalue=9e-48,
Organism=Caenorhabditis elegans, GI17507255, Length=119, Percent_Identity=34.453781512605, Blast_Score=69, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6323504, Length=327, Percent_Identity=29.3577981651376, Blast_Score=116, Evalue=5e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00107 ADH_zinc_N [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 36403; Mature: 36272

Theoretical pI: Translated: 7.22; Mature: 7.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPQTKTTNRRIVLHSRPKGAPTPENFRTETAAVPVPAPGEVLLRTIWLSLDPYMRGRMND
CCCCCCCCCEEEEEECCCCCCCCCCCCCCCEECCCCCCHHHHHHHHHHHCCHHHHCCCCC
APSYAAPVWLGGVMVGGTVSRVVSSSVPAFRDGDLVLSNAGWQDYAVSDGTDLMPLADVA
CCCCCCHHHCCCEEECHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCCCCCCCHHHHC
HPSYALGVLGMPGFTAYFGLLHIGEPKAGETVAVAAASGAVGAVVGQIAKLKGCRVVGIA
CCCCEEEECCCCHHHHHHHHHCCCCCCCCCEEEEEECCCHHHHHHHHHHHHCCCEEEEEC
GGADKCRYVAGTLGFDACVDHHDPDFAKQLAAACPDGIDVYFENVGGAVFDAVLPLLNDH
CCCCHHEEEECCCCHHHHHCCCCHHHHHHHHHHCCCCCEEHHHHCCHHHHHHHHHHHCCC
ARVPVCGLIAHYNDSELPGGPNRLPLLTSSVLRKRIRMQGFIILDHYANVYPAFLKDMSE
CCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHCCEEEEECHHHHHHHHHHHHHH
WVAQGKVKPREDVVDGLDAAPRALIGLLGGKNFGKVVVRVGPDTL
HHHCCCCCCHHHHHHCCCHHHHHHHHHHCCCCCCEEEEEECCCCC
>Mature Secondary Structure 
PQTKTTNRRIVLHSRPKGAPTPENFRTETAAVPVPAPGEVLLRTIWLSLDPYMRGRMND
CCCCCCCCEEEEEECCCCCCCCCCCCCCCEECCCCCCHHHHHHHHHHHCCHHHHCCCCC
APSYAAPVWLGGVMVGGTVSRVVSSSVPAFRDGDLVLSNAGWQDYAVSDGTDLMPLADVA
CCCCCCHHHCCCEEECHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCCCCCCCHHHHC
HPSYALGVLGMPGFTAYFGLLHIGEPKAGETVAVAAASGAVGAVVGQIAKLKGCRVVGIA
CCCCEEEECCCCHHHHHHHHHCCCCCCCCCEEEEEECCCHHHHHHHHHHHHCCCEEEEEC
GGADKCRYVAGTLGFDACVDHHDPDFAKQLAAACPDGIDVYFENVGGAVFDAVLPLLNDH
CCCCHHEEEECCCCHHHHHCCCCHHHHHHHHHHCCCCCEEHHHHCCHHHHHHHHHHHCCC
ARVPVCGLIAHYNDSELPGGPNRLPLLTSSVLRKRIRMQGFIILDHYANVYPAFLKDMSE
CCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHCCEEEEECHHHHHHHHHHHHHH
WVAQGKVKPREDVVDGLDAAPRALIGLLGGKNFGKVVVRVGPDTL
HHHCCCCCCHHHHHHCCCHHHHHHHHHHCCCCCCEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]