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The map label for this gene is yfhM [H]

Identifier: 126443513

GI number: 126443513

Start: 1285234

End: 1286124

Strand: Reverse

Name: yfhM [H]

Synonym: BURPS668_A1365

Alternate gene names: 126443513

Gene position: 1286124-1285234 (Counterclockwise)

Preceding gene: 126442598

Following gene: 126444926

Centisome position: 41.12

GC content: 72.17

Gene sequence:

>891_bases
TTGGATGAAGCGCGCCGCGTCACCTCGTTCCACCACGATGGATTGACTTTCGACGCCGTCGATACGGGCCCGCTCGACGG
CGAGGTCATCGTGCTGCTGCACGGCTGGCCGCAGACGGCGAAGTGCTGGGCGCGCGTCGCGGCGCGGCTGAATGCCGACG
GCTATCGCACGGTCGCGCCGAACCAGCGCGGCTACTCGCCGCTCGCCCGCCCCCGCCGCGTCGGCGCATACCGGATGCCG
CATCTCGTCGGCGACGTCGTCGCGCTGATCGAGCGGCTCGGCGGCGGCCCGGTCCATGTCGTCGGGCACGACTGGGGCGC
CGCGGTCGCATGGGCGCTCGCGGGCCGGCATCCCGCCGCGGTGCGCACGTTGACGACGGTGTCGGTGCCGCACTCGGGCG
CGTTCATGCGCTCGATGCTCAGCAGCGACCAGTTGTTCCGCTCGTACTATATGGGCCTCTTCCAGTTGCCGAAGCTGCCG
GAGCTGTTCGTCACGCGCTGCCGCGGGCTGTTCGAGAAAATGCTCACGGGCACGGGCATGACGCGCGACGAGGTGGACAC
CGTCTACGCCGACATCGTCGAGGCAGGCGCGCTGACGACGTCGCTCAACTGGTATCGCGCGATGATGTTGACGCCGCCCG
GCTATCTGACCCGCAAGGTGCCCGTGCCCGTCCTGCACGTGTGGGGCGCGCGGGACGCGGCGCTGTCGCGGCGCGGCGCC
GAGCTCGCGCGCGAGTTCGCGAGCGGCCCGTACCGGCTCGAGGTGCTGCCGCACGCGACGCACTGGATTCCCGAGCACGA
CGCCGAGCGGCTCGCCGCGCTCGTGCGCGAATCGATCGCGGTGAAGCCGGGCGCGGCGCCCGGCCCGCTCGCGGCGGCCG
CCGCGAACTGA

Upstream 100 bases:

>100_bases
CCGTCGGCTGCCGGCTGCCGGCCGAAGCGTCTGCGCCGCCGAACGCGCCGCGGGCATGCGCGAGACGCGCGATCGAAGCA
GGAAATCAGGAGAACCGACC

Downstream 100 bases:

>100_bases
TCGACGCCTGCCCGCGCTCCCGCCGCACGCCGCACGCCGGCCCGCCGCGCGGCGGCGCGCTCAGTCCGCGAGTTCGATGC
CCGCGCGCTCCATCGCGCGC

Product: alpha/beta fold family hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 296; Mature: 296

Protein sequence:

>296_residues
MDEARRVTSFHHDGLTFDAVDTGPLDGEVIVLLHGWPQTAKCWARVAARLNADGYRTVAPNQRGYSPLARPRRVGAYRMP
HLVGDVVALIERLGGGPVHVVGHDWGAAVAWALAGRHPAAVRTLTTVSVPHSGAFMRSMLSSDQLFRSYYMGLFQLPKLP
ELFVTRCRGLFEKMLTGTGMTRDEVDTVYADIVEAGALTTSLNWYRAMMLTPPGYLTRKVPVPVLHVWGARDAALSRRGA
ELAREFASGPYRLEVLPHATHWIPEHDAERLAALVRESIAVKPGAAPGPLAAAAAN

Sequences:

>Translated_296_residues
MDEARRVTSFHHDGLTFDAVDTGPLDGEVIVLLHGWPQTAKCWARVAARLNADGYRTVAPNQRGYSPLARPRRVGAYRMP
HLVGDVVALIERLGGGPVHVVGHDWGAAVAWALAGRHPAAVRTLTTVSVPHSGAFMRSMLSSDQLFRSYYMGLFQLPKLP
ELFVTRCRGLFEKMLTGTGMTRDEVDTVYADIVEAGALTTSLNWYRAMMLTPPGYLTRKVPVPVLHVWGARDAALSRRGA
ELAREFASGPYRLEVLPHATHWIPEHDAERLAALVRESIAVKPGAAPGPLAAAAAN
>Mature_296_residues
MDEARRVTSFHHDGLTFDAVDTGPLDGEVIVLLHGWPQTAKCWARVAARLNADGYRTVAPNQRGYSPLARPRRVGAYRMP
HLVGDVVALIERLGGGPVHVVGHDWGAAVAWALAGRHPAAVRTLTTVSVPHSGAFMRSMLSSDQLFRSYYMGLFQLPKLP
ELFVTRCRGLFEKMLTGTGMTRDEVDTVYADIVEAGALTTSLNWYRAMMLTPPGYLTRKVPVPVLHVWGARDAALSRRGA
ELAREFASGPYRLEVLPHATHWIPEHDAERLAALVRESIAVKPGAAPGPLAAAAAN

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. Epoxide hydrolase family [H]

Homologues:

Organism=Homo sapiens, GI218777837, Length=273, Percent_Identity=28.9377289377289, Blast_Score=127, Evalue=9e-30,
Organism=Homo sapiens, GI218777840, Length=267, Percent_Identity=31.8352059925094, Blast_Score=121, Evalue=8e-28,
Organism=Homo sapiens, GI13376164, Length=267, Percent_Identity=31.8352059925094, Blast_Score=121, Evalue=8e-28,
Organism=Homo sapiens, GI27597073, Length=244, Percent_Identity=25, Blast_Score=72, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17562298, Length=281, Percent_Identity=30.2491103202847, Blast_Score=131, Evalue=4e-31,
Organism=Caenorhabditis elegans, GI17554012, Length=275, Percent_Identity=27.6363636363636, Blast_Score=124, Evalue=6e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR000639 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: NA

Molecular weight: Translated: 32268; Mature: 32268

Theoretical pI: Translated: 9.55; Mature: 9.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDEARRVTSFHHDGLTFDAVDTGPLDGEVIVLLHGWPQTAKCWARVAARLNADGYRTVAP
CCCHHHHHHHCCCCCEEECCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHCCCCCEEECC
NQRGYSPLARPRRVGAYRMPHLVGDVVALIERLGGGPVHVVGHDWGAAVAWALAGRHPAA
CCCCCCCCCCCHHCCCHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHCCCCHH
VRTLTTVSVPHSGAFMRSMLSSDQLFRSYYMGLFQLPKLPELFVTRCRGLFEKMLTGTGM
HEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCC
TRDEVDTVYADIVEAGALTTSLNWYRAMMLTPPGYLTRKVPVPVLHVWGARDAALSRRGA
CHHHHHHHHHHHHHHCCHHEEHHHHEEEEECCCCCCEECCCCCEEEECCCCHHHHHHHHH
ELAREFASGPYRLEVLPHATHWIPEHDAERLAALVRESIAVKPGAAPGPLAAAAAN
HHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHCCCC
>Mature Secondary Structure
MDEARRVTSFHHDGLTFDAVDTGPLDGEVIVLLHGWPQTAKCWARVAARLNADGYRTVAP
CCCHHHHHHHCCCCCEEECCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHCCCCCEEECC
NQRGYSPLARPRRVGAYRMPHLVGDVVALIERLGGGPVHVVGHDWGAAVAWALAGRHPAA
CCCCCCCCCCCHHCCCHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHCCCCHH
VRTLTTVSVPHSGAFMRSMLSSDQLFRSYYMGLFQLPKLPELFVTRCRGLFEKMLTGTGM
HEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCC
TRDEVDTVYADIVEAGALTTSLNWYRAMMLTPPGYLTRKVPVPVLHVWGARDAALSRRGA
CHHHHHHHHHHHHHHCCHHEEHHHHEEEEECCCCCCEECCCCCEEEECCCCHHHHHHHHH
ELAREFASGPYRLEVLPHATHWIPEHDAERLAALVRESIAVKPGAAPGPLAAAAAN
HHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8946165; 9384377 [H]