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The map label for this gene is ttuB [H]

Identifier: 126443214

GI number: 126443214

Start: 1077076

End: 1078413

Strand: Reverse

Name: ttuB [H]

Synonym: BURPS668_A1121

Alternate gene names: 126443214

Gene position: 1078413-1077076 (Counterclockwise)

Preceding gene: 126442841

Following gene: 126444825

Centisome position: 34.48

GC content: 70.55

Gene sequence:

>1338_bases
ATGTCCACGCCTCATGCCGAAGCCTTCTGCGCGCCCGCCGGCAGCGCGCGCGCATCGCTGAACCGCCTGCTGTTTCGCAA
GCTGATGCCGATTCTGATCACCGCGTACGTGATCAGCTTTCTCGACCGCACGAACATCGCGTTCGCGAAGCATTCGATGG
GCATCGATCTCGGCCTCTCGTCGGCCGCCTACGGCCTCGGCGCGGGGCTCTTCTTCGTCACGTACGCATTGTTCGAGATC
CCGAGCAATCTGATCATGCATCGCGTCGGCGCACGCTTCTGGATCGCGCGGATCATGATCACTTGGGGCGCGCTATCCGT
CGCGATGGCGCTCGTGCGCGGCGAGACGTCGTTCTACGCGATGCGGCTGCTGCTCGGCGCCGCCGAAGCGGGGCTCTTTC
CCGGCGTGATGCTGTATCTGACGTACTGGTTCGGCCGCGAGGAACGTGCGCGCGCGACCGGCTATTTCCTGCTCGGCGTA
TGCGTGGCGAACATCGTCGGCGGCCCGCTCGCGGGCGCGCTGCTCGCACTCGACGGCGCGCTCGGGCTGCACGGCTGGCA
GTGGCTCTTCATCGTCGAAGGCGTGCCGGCGATCGCGCTCGCCTTCGTCGTCTGGGCCCGCCTGCCGGAGCGGCCGAGCA
ACGCCCGCTGGCTCGCGCCCGAGCTCGGCCGCGCACTCGAGCGCGCGCTCGCGAGCGAGCAGGCACAGGGCGCGGCGGCG
CACGGCGCGCAGGCGTTCGGCGTCGCGCTGCGCGATCCGCAGATCTGGCTCGCGATCTTCGTGTACTTCTGCCATCAACT
GACGATCTACACGATGATCTTCTTCCTGCCCGGCATCATCGGCGAATCGGGGCGCTTCAGCCCGATCGTCGTCGGCCTGC
TCGCCGCGATGCCGTGGCTTGCCGCGGCGCTCGGCGCGGCGACATTGCCGCGCTTCGCGCGCGATTCGTCGCGATCGCGG
CGGATTCTGTGCGCGGGGCTCGGGGTGATGGCCGCGGGGCTCGTCTGCGCGGCGTATGCGCCGCCCGCGGCCGCGCTCGC
GAGCGTGTGCGTCGCCGCGTCGATGTTCTTCGTCGTGCAATCGATCGTCTTCACGTTCCCGGCCTCGCGCCTCGCGGGCA
GCGCGCTCGCGGGCGGGCTCGGCCTCGTCAATACGTGCGGCCTGCTCGGCGGCTTCGTCGGGCCGACCGTCGTCGGCACG
ATCGAGCAGACGACCGGCCACGCGAAGAACGGTCTCGCGTTGCTCGCGATCGCGCTCGGCGTCGCCGCGCTCGCGAGCCT
GCGGCTGCGGCACGGGCACGAATGCGCGCACCCGGCGCGGCCGAGCCGCGCGCGGTGA

Upstream 100 bases:

>100_bases
AGCGCCGCCGGCGCGCGACCCGCGCATCTGCCCGTCATCTGCTGAACGCGGAGCGCCGTGCTTGCCGTGCGCTCCGGCTC
GTTCCCACGGAGCCGCACTT

Downstream 100 bases:

>100_bases
GCGGTGAGCGGTGAGCGGTGAGCGGTGAGCGATGAACGATGAACGATGAACGATGAACGATGAACGGCGGTCCGCGTGCG
CCCGCCGCCGCCCGTCAGCG

Product: major facilitator family transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 445; Mature: 444

Protein sequence:

>445_residues
MSTPHAEAFCAPAGSARASLNRLLFRKLMPILITAYVISFLDRTNIAFAKHSMGIDLGLSSAAYGLGAGLFFVTYALFEI
PSNLIMHRVGARFWIARIMITWGALSVAMALVRGETSFYAMRLLLGAAEAGLFPGVMLYLTYWFGREERARATGYFLLGV
CVANIVGGPLAGALLALDGALGLHGWQWLFIVEGVPAIALAFVVWARLPERPSNARWLAPELGRALERALASEQAQGAAA
HGAQAFGVALRDPQIWLAIFVYFCHQLTIYTMIFFLPGIIGESGRFSPIVVGLLAAMPWLAAALGAATLPRFARDSSRSR
RILCAGLGVMAAGLVCAAYAPPAAALASVCVAASMFFVVQSIVFTFPASRLAGSALAGGLGLVNTCGLLGGFVGPTVVGT
IEQTTGHAKNGLALLAIALGVAALASLRLRHGHECAHPARPSRAR

Sequences:

>Translated_445_residues
MSTPHAEAFCAPAGSARASLNRLLFRKLMPILITAYVISFLDRTNIAFAKHSMGIDLGLSSAAYGLGAGLFFVTYALFEI
PSNLIMHRVGARFWIARIMITWGALSVAMALVRGETSFYAMRLLLGAAEAGLFPGVMLYLTYWFGREERARATGYFLLGV
CVANIVGGPLAGALLALDGALGLHGWQWLFIVEGVPAIALAFVVWARLPERPSNARWLAPELGRALERALASEQAQGAAA
HGAQAFGVALRDPQIWLAIFVYFCHQLTIYTMIFFLPGIIGESGRFSPIVVGLLAAMPWLAAALGAATLPRFARDSSRSR
RILCAGLGVMAAGLVCAAYAPPAAALASVCVAASMFFVVQSIVFTFPASRLAGSALAGGLGLVNTCGLLGGFVGPTVVGT
IEQTTGHAKNGLALLAIALGVAALASLRLRHGHECAHPARPSRAR
>Mature_444_residues
STPHAEAFCAPAGSARASLNRLLFRKLMPILITAYVISFLDRTNIAFAKHSMGIDLGLSSAAYGLGAGLFFVTYALFEIP
SNLIMHRVGARFWIARIMITWGALSVAMALVRGETSFYAMRLLLGAAEAGLFPGVMLYLTYWFGREERARATGYFLLGVC
VANIVGGPLAGALLALDGALGLHGWQWLFIVEGVPAIALAFVVWARLPERPSNARWLAPELGRALERALASEQAQGAAAH
GAQAFGVALRDPQIWLAIFVYFCHQLTIYTMIFFLPGIIGESGRFSPIVVGLLAAMPWLAAALGAATLPRFARDSSRSRR
ILCAGLGVMAAGLVCAAYAPPAAALASVCVAASMFFVVQSIVFTFPASRLAGSALAGGLGLVNTCGLLGGFVGPTVVGTI
EQTTGHAKNGLALLAIALGVAALASLRLRHGHECAHPARPSRAR

Specific function: Component of the tartrate utilization system and may allow entry of tartrate and tartrate dehydrogenase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Escherichia coli, GI87082071, Length=427, Percent_Identity=38.4074941451991, Blast_Score=270, Evalue=9e-74,
Organism=Escherichia coli, GI87082320, Length=446, Percent_Identity=27.1300448430493, Blast_Score=88, Evalue=9e-19,
Organism=Escherichia coli, GI2367379, Length=277, Percent_Identity=24.9097472924188, Blast_Score=79, Evalue=8e-16,
Organism=Escherichia coli, GI2367193, Length=417, Percent_Identity=22.0623501199041, Blast_Score=62, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI17540458, Length=248, Percent_Identity=25, Blast_Score=72, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17569727, Length=181, Percent_Identity=25.9668508287293, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI71991453, Length=239, Percent_Identity=22.1757322175732, Blast_Score=65, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI71991448, Length=239, Percent_Identity=22.1757322175732, Blast_Score=65, Evalue=1e-10,
Organism=Saccharomyces cerevisiae, GI6321698, Length=292, Percent_Identity=25.6849315068493, Blast_Score=93, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6322025, Length=194, Percent_Identity=28.8659793814433, Blast_Score=91, Evalue=4e-19,
Organism=Saccharomyces cerevisiae, GI6319250, Length=230, Percent_Identity=23.9130434782609, Blast_Score=74, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6322612, Length=238, Percent_Identity=24.7899159663866, Blast_Score=72, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6319876, Length=221, Percent_Identity=25.7918552036199, Blast_Score=72, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 46910; Mature: 46779

Theoretical pI: Translated: 10.05; Mature: 10.05

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTPHAEAFCAPAGSARASLNRLLFRKLMPILITAYVISFLDRTNIAFAKHSMGIDLGLS
CCCCCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCC
SAAYGLGAGLFFVTYALFEIPSNLIMHRVGARFWIARIMITWGALSVAMALVRGETSFYA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
MRLLLGAAEAGLFPGVMLYLTYWFGREERARATGYFLLGVCVANIVGGPLAGALLALDGA
HHHHHHHHHHCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCH
LGLHGWQWLFIVEGVPAIALAFVVWARLPERPSNARWLAPELGRALERALASEQAQGAAA
HCCCCEEEEEEECCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHH
HGAQAFGVALRDPQIWLAIFVYFCHQLTIYTMIFFLPGIIGESGRFSPIVVGLLAAMPWL
CCCHHHCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
AAALGAATLPRFARDSSRSRRILCAGLGVMAAGLVCAAYAPPAAALASVCVAASMFFVVQ
HHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
SIVFTFPASRLAGSALAGGLGLVNTCGLLGGFVGPTVVGTIEQTTGHAKNGLALLAIALG
HHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHEEEHHHHCCCCCCCHHHHHHHHH
VAALASLRLRHGHECAHPARPSRAR
HHHHHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure 
STPHAEAFCAPAGSARASLNRLLFRKLMPILITAYVISFLDRTNIAFAKHSMGIDLGLS
CCCCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCC
SAAYGLGAGLFFVTYALFEIPSNLIMHRVGARFWIARIMITWGALSVAMALVRGETSFYA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
MRLLLGAAEAGLFPGVMLYLTYWFGREERARATGYFLLGVCVANIVGGPLAGALLALDGA
HHHHHHHHHHCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCH
LGLHGWQWLFIVEGVPAIALAFVVWARLPERPSNARWLAPELGRALERALASEQAQGAAA
HCCCCEEEEEEECCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHH
HGAQAFGVALRDPQIWLAIFVYFCHQLTIYTMIFFLPGIIGESGRFSPIVVGLLAAMPWL
CCCHHHCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
AAALGAATLPRFARDSSRSRRILCAGLGVMAAGLVCAAYAPPAAALASVCVAASMFFVVQ
HHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
SIVFTFPASRLAGSALAGGLGLVNTCGLLGGFVGPTVVGTIEQTTGHAKNGLALLAIALG
HHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHEEEHHHHCCCCCCCHHHHHHHHH
VAALASLRLRHGHECAHPARPSRAR
HHHHHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7592429 [H]