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The map label for this gene is lgrC [H]

Identifier: 126442685

GI number: 126442685

Start: 1589041

End: 1593645

Strand: Reverse

Name: lgrC [H]

Synonym: BURPS668_A1649

Alternate gene names: 126442685

Gene position: 1593645-1589041 (Counterclockwise)

Preceding gene: 126442531

Following gene: 126445068

Centisome position: 50.96

GC content: 69.38

Gene sequence:

>4605_bases
ATGCTCCAAGCTGTCAATGACACATTGCCGCTCACGAACAGCCAGATGGCAATGTGGTTGCAATGGAAATACGCGCCTGA
CGACCCCGCCTATAACAATCCGCTGCTTTTCGAGCTCGACGGAGATATCGATGTCGAGCGGTTAAAAGATGCATTTGCCG
CGGTGGCCGATGCGCATCCGGCCATTCGCATGCGCTTTATCGAGCGCGCGGGCGTGCCGCTTCAATACAGCGCGTCGCAT
CCGCACGGGCCGCTCGAATTCATCGATCTGTCGGACGTCGAACCCGCGGCGCGCGCGCCGCGGATCGACGCCGCAATCGG
CGCCTGCCTGCTCGAACCGTTCGATTTGCTAACCGAGCCCGTCTACCGGTTCGTGCTGGTGAGGACTCGGCCGCGCGGCT
ATCTGCTGGCGCTGAACATCCACCACATCTGCGTGGACGGCGCATCGGCGCTGATCCTGCTGGACGACATCTCGTCCGCC
TACGCCGATCCCGCCGCTTACGCGGCCGCGTCGGCCGCGCGCACGGGCGAGGGGTTCGGCGACGTGCTGGAGGTCGAGCG
GCGGCGCTGGGCGGACGGCGTTCATGCGCAGGCCGAAACGGCGTGGCGCGCGCATCTGGCCGATCGGGTGTGCAGCGTCG
AGTTCGGCAAGCTCGCCTTCGACGGCGAGCGTGCGGCGGGCGGCGGCGCGGGGCAATATCGATGGACGCTGCCCGATACG
CTGCCGGCGAAGATCAAGGCCGTCAACCGCCTGACGCGAACGACGCCGTTCGTCGTCCTGATGAGCGCGTTCGGCGTGCT
GCTGCACCGCTATCTGCAGCAGGACGCGCTCGCGATCGCCTATCCGGTCGATACGCGGCCCGCCGGGTTTGCGCGGATCT
TCGGCTCGTTCATCAATTTCGTGCCGGCGTTCGTCGACGTCTCGCCGGACCTGACGGCCGGCGCGCTCTTCGACAAGGTG
CGCGAGCAGCGGCGCCGAACGAAGGCGATCGCGGATTTCCCGCAGGTCGATCTGATGCGGCTCGCGCGGCGAACCCTGGC
CGACGCGGCGTTGCCGTGCCTCAACGTGGCGCTCGTGCCCGCGCGTTTCGCGCTCGATTCGCTGAGGTTCGACGGCGTGC
GCGTCGAGCAGCGGCACTGCTTCACTGGCGCGGCCAAGCAGGATCTGGCGCTGCTTTACGACGGCGACGAGACGCTGAGC
CTGATCCTCGAATACCGGCACGGCTTGCTGGACGAAGCGATCGCGCGCCGGATGGCGGGCGACTTGAACGTCATCGTCGA
GCGGATCGTCGAGCGGCCGGATCTGCGCCTCGGCGATCTGACGCTGTCGGATCACCGCGCGTTCGCCGAGCGCTACGCGA
CGCTCGCCGACGCCGCGCCCCGCACGCCGGCGCTTGCGGCGATCGAGCGCGGATGGCGCGAGCAGCCCGAGCGAATCGTC
GCCGGCGAGCCGGGCAACGCGGTGTCCGCCCGGCAGTTGCTCGATGCGTCGAACCGCGTCGCGCGCCGGCTCGCGGCGGC
GAACGTGAAGCCGGGCGAGCGCGTCGGCGTGCGAATGGACCGCGGCGGGGCGCTGCTGGCGGCGCTCGTCGGCATCTGGA
AGCTCGGCGCGGTGTACGTGCCGCTGCCGACGGATCTGCCGGGTGCGCGCCGCGCGCACATCGCGGACGACGCGCAGCTT
GCGGCGTGCCTGCATCGGGCCGAACCGGCCGACCCGACGCCGCGCGACCTCGTGCTGGCCGACGACATCTTCGATGCGTC
GGATGCCGAAGCGCTTGCCGACTTCGCCGTCGATCCGGACAGCGTCGCATATCTGATCTACACGTCGGGCTCCACCGGCG
CGCCGAAAGGCGTCGAGGTGACGCATCGCAACGTCGCGAGCTTCCTGCTCGCGATGGCGCGCGCGCTGCCGATGGGCCGC
GACGATCGCCTGCTCGCGACGACGACGATCGGCTTCGACATCTCGCTGCTCGAGCTGCTGCTTCCGCCGACGGTCGGCGC
GGCGGTCATCGCGTGCCCGGAGCACATGCGCATCGATGCGAAGGCGCTCGAACGCGTGATCGCCGACGAGCGCGTCACGT
GGCTGCAGGGCACGCCGTCGTTCTTCAACGTGCTGCGCGCGGGCGGCTGGCGCGGCGACAAGCGCCTGAACATTCTGTGC
GGCGGCGAGCCGATCGACGCGTCGACCTACGGCTTCCTGCGCGAGACGTGCGCGGCGGTCTGGCAGGTCTACGGCCCGAC
CGAAGCGACGATCTGGTCGACGATCGCGGGCCCCGACGCGGATGGCGTCGAGGGGCTGGGCGAGCCGCTTCGCAATACGA
CGATTCATCTGCTGGACGCGCACGGCCAGCAGGTGCCGCGCTTCAGCAAGGGCGAGATCTGCATCGGCGGGCACGGCGTC
GCACGCGGCTATCGCCATCGCGCCGCATTGAGCGCCGAGCGCTTCGTGCACGTGGCCGGCGCCGGCCGCGTCTATCGGAC
CGGCGACTTCGCGTTTCGCGATGCGCACGACCGACTGCGCTTTCTCGGGCGCGAGGACGGACAGGTCAAGATCCGCGGCT
TTCGGGTCGAGCTCGGCGAAATCGAACGGCAGATCGAAGCGCTCGGCGGGGTTCGGAAAGCCGTCGTGCTCGTGCGGCGC
GCGACGGCCGCCGAGCCGACGCTGATCGCATGGTGCGAGCCGCATGCGGGCCGCGCGCTCGATGCCGATGCGCTGCGGGC
GGCGCTCGCCGACGCGCTGCCCGCCTACATGACGCCCGCGCGGATCGAGCCAATCGATGCGTGGCCGCTCAACGCGAACG
GCAAGATCGATCGCGGCGCGCTCGCCGGGCGCGCGAGCGCGCCGCAGGCGCCGCCGCTCGAGCCGCGCGATTCGGTCGAT
CCGCTCGTGCCGACGTTGCAGGCGATCTACGCGGACGTGCTGCGTCTCGATACGGTCGACCCTCGCGCGACGCTGATGTC
GCTCGGCGGCCATTCGCTATCCGCCGTGCGGATCATCGCGCGGATCCAGCAGCAACTGAAGGTCGACGTCGGCCTGGAAA
CGTTCATGGCGAATTCGAGCGTCATCGGATTGATCGGCAGCCTGCGGGCGTCGGGCGTGCCGGCCGACGGCGGTAGCGGC
GGCGCAGTCGCGCCCGGCGGCGACGAGCGTTCGTCGCCGCCCGAAGCCGCGTACGCGGCCTCACGCACGAGCGATACCGC
GCGCCGGCCCGCGACGGCGGCGGATGCCACGCCCGCGCCGGAGTCGAACGCCGCATCCGGCTGCGCGCCGCACGTATCGC
CGCGGACGCTGCAGCCGTCGGCCAGCGAAAAGGCGCTGTACTTCCTCGACAGCGTTTCGGCGGTGAGGCAGACGTACAAC
ATTCCGGTGGGGCTGCATTTCCCGGAGGGCGTGAACGCCGACGCGCTCGAGCGCGCGCTGCGTCACGTGCTCGACACGCA
TGGCGCGCTGCGCGCGGCGTTCGAGCCGAGCGCCGACGGACTGGTCAAGCGCATGGTTCCGACGCCCGCCGGCGCGCTGA
TCGCGCGCCACGCGCCGACCGATCTCGCGACGCTTGTGCCGACGCTGAACCGGATGCTGCGCGAGCCGTTCGAGCTGCAC
GAAGGGCCGCTGATGCGCGCGCATCATTTTCCGCTGGAGGACGGTGGCGCGGCGGTGTTCTATCTGTTTCACCACATCAT
CGTGGACGGGATCGGCTGCGGCAATTTCCTGAGGGAACTGGCGGGCGCGTACGAGGCGCTGGTCGGCGGCATGGAGCCCG
GCGGCGACGGCGCTTCGTCGGGCGACGGCAACGGCAACGGCAACGGCAACGACAACAGTGACGGCGACGGCGATCGTCAG
ACGAACGCCGCCGCGCGCGTCGACGAACTCATCGAGCGATTCGGCATCGTCGATCGCGTGCTGAACCTGCCGTATCGCGC
GCCGTTCCCCGAAGTGCGCACGCTCGCGGGCGACAGCCTTCCGCTCGAGATTTCCGCCGGCTTGCGCGCCGAGCTCGACG
AATATTCGCGCGCCGCGGGCGTGCCGCTCGCGACGCTCTTGCTGAGCGCGTTCGTGCTGACGCTGCATCGCCTGAGCGGC
GATCGAACCATCAACGTCGGGCTGGCGACGATGAACCGCACGCCCGAGACGCTCGGCAAGATCGGCCTCTATACGAACAC
GATCGTGCTGCCCGTCGACATCGAGCCGGCGGACCGCCTGGGCGACTTCGTCGACCGGGTGACGGCTGCGCTGTTCTCGA
TCTACGGCTATGCCGACGTGCCGTTCGAGGAAGTCGCGGGCCGCCTCGTCGAGTATGCGTCGCTCGGCCGAACCCCGGTT
TTTCAGGCGTTTTTCAACTTCATCGACCGCTCGATGTACGCGTTCTCGATGGCGGGGCTGCCGGTGCGGGAGATTGCGCT
GCGCCCGACCGGCTCGAAGTTCGAGCTGTCGCTCGAAGTCAACGATTTCCGCACGCACACGCAAGTCTTCTTCGAATACA
GCAAGGACGTGTTCGACGAGGCACTTGTCGGCGACATCGCGTCCGAATTCGCCCGCACCCTGCTGGCCTGCGTGCGCTCG
CCGGGCGACGCGGTCGAGCGGTTCGCCCTGACCACGCAATCTTGA

Upstream 100 bases:

>100_bases
GTTACTGATGCGAAGGGGCCAAGTTATGCTTTTCGCGAAATAATTCAACGAATTCAATAGCCGGAATTCGATTTCGTCAC
GCAAACTTCAGGAATGCCGC

Downstream 100 bases:

>100_bases
GGAAAACATGGAACAGGTAGCACTGATTGGATCCAGACTGCGGCTGCCCGGCGCCGATACCGTCGATGCGTTCTGGCAGA
ACGTTCTGGCCGGCCGGGAT

Product: putative siderophore non-ribosomal peptide synthetase MbaF

Products: pyrophosphate; AMP; enterobactin; pyrophosphate; L-Seryl-AMP [C]

Alternate protein names: ATP-dependent valine adenylase; ValA; Valine activase; ATP-dependent D-valine adenylase; D-ValA; D-valine activase; Valine racemase [ATP-hydrolyzing]; ATP-dependent tryptophan adenylase; TrpA; Tryptophan activase; ATP-dependent D-leucine adenylase; D-LeuA; D-leucine activase; Leucine racemase [ATP-hydrolyzing]; ATP-dependent tryptophan/phenylalanine/tyrosine adenylase; Trp/Phe/TyrA; Tryptophan/phenylalanine/tyrosine activase; ATP-dependent D-leucine adenylase; D-LeuA; D-leucine activase; Leucine racemase [ATP-hydrolyzing] [H]

Number of amino acids: Translated: 1534; Mature: 1534

Protein sequence:

>1534_residues
MLQAVNDTLPLTNSQMAMWLQWKYAPDDPAYNNPLLFELDGDIDVERLKDAFAAVADAHPAIRMRFIERAGVPLQYSASH
PHGPLEFIDLSDVEPAARAPRIDAAIGACLLEPFDLLTEPVYRFVLVRTRPRGYLLALNIHHICVDGASALILLDDISSA
YADPAAYAAASAARTGEGFGDVLEVERRRWADGVHAQAETAWRAHLADRVCSVEFGKLAFDGERAAGGGAGQYRWTLPDT
LPAKIKAVNRLTRTTPFVVLMSAFGVLLHRYLQQDALAIAYPVDTRPAGFARIFGSFINFVPAFVDVSPDLTAGALFDKV
REQRRRTKAIADFPQVDLMRLARRTLADAALPCLNVALVPARFALDSLRFDGVRVEQRHCFTGAAKQDLALLYDGDETLS
LILEYRHGLLDEAIARRMAGDLNVIVERIVERPDLRLGDLTLSDHRAFAERYATLADAAPRTPALAAIERGWREQPERIV
AGEPGNAVSARQLLDASNRVARRLAAANVKPGERVGVRMDRGGALLAALVGIWKLGAVYVPLPTDLPGARRAHIADDAQL
AACLHRAEPADPTPRDLVLADDIFDASDAEALADFAVDPDSVAYLIYTSGSTGAPKGVEVTHRNVASFLLAMARALPMGR
DDRLLATTTIGFDISLLELLLPPTVGAAVIACPEHMRIDAKALERVIADERVTWLQGTPSFFNVLRAGGWRGDKRLNILC
GGEPIDASTYGFLRETCAAVWQVYGPTEATIWSTIAGPDADGVEGLGEPLRNTTIHLLDAHGQQVPRFSKGEICIGGHGV
ARGYRHRAALSAERFVHVAGAGRVYRTGDFAFRDAHDRLRFLGREDGQVKIRGFRVELGEIERQIEALGGVRKAVVLVRR
ATAAEPTLIAWCEPHAGRALDADALRAALADALPAYMTPARIEPIDAWPLNANGKIDRGALAGRASAPQAPPLEPRDSVD
PLVPTLQAIYADVLRLDTVDPRATLMSLGGHSLSAVRIIARIQQQLKVDVGLETFMANSSVIGLIGSLRASGVPADGGSG
GAVAPGGDERSSPPEAAYAASRTSDTARRPATAADATPAPESNAASGCAPHVSPRTLQPSASEKALYFLDSVSAVRQTYN
IPVGLHFPEGVNADALERALRHVLDTHGALRAAFEPSADGLVKRMVPTPAGALIARHAPTDLATLVPTLNRMLREPFELH
EGPLMRAHHFPLEDGGAAVFYLFHHIIVDGIGCGNFLRELAGAYEALVGGMEPGGDGASSGDGNGNGNGNDNSDGDGDRQ
TNAAARVDELIERFGIVDRVLNLPYRAPFPEVRTLAGDSLPLEISAGLRAELDEYSRAAGVPLATLLLSAFVLTLHRLSG
DRTINVGLATMNRTPETLGKIGLYTNTIVLPVDIEPADRLGDFVDRVTAALFSIYGYADVPFEEVAGRLVEYASLGRTPV
FQAFFNFIDRSMYAFSMAGLPVREIALRPTGSKFELSLEVNDFRTHTQVFFEYSKDVFDEALVGDIASEFARTLLACVRS
PGDAVERFALTTQS

Sequences:

>Translated_1534_residues
MLQAVNDTLPLTNSQMAMWLQWKYAPDDPAYNNPLLFELDGDIDVERLKDAFAAVADAHPAIRMRFIERAGVPLQYSASH
PHGPLEFIDLSDVEPAARAPRIDAAIGACLLEPFDLLTEPVYRFVLVRTRPRGYLLALNIHHICVDGASALILLDDISSA
YADPAAYAAASAARTGEGFGDVLEVERRRWADGVHAQAETAWRAHLADRVCSVEFGKLAFDGERAAGGGAGQYRWTLPDT
LPAKIKAVNRLTRTTPFVVLMSAFGVLLHRYLQQDALAIAYPVDTRPAGFARIFGSFINFVPAFVDVSPDLTAGALFDKV
REQRRRTKAIADFPQVDLMRLARRTLADAALPCLNVALVPARFALDSLRFDGVRVEQRHCFTGAAKQDLALLYDGDETLS
LILEYRHGLLDEAIARRMAGDLNVIVERIVERPDLRLGDLTLSDHRAFAERYATLADAAPRTPALAAIERGWREQPERIV
AGEPGNAVSARQLLDASNRVARRLAAANVKPGERVGVRMDRGGALLAALVGIWKLGAVYVPLPTDLPGARRAHIADDAQL
AACLHRAEPADPTPRDLVLADDIFDASDAEALADFAVDPDSVAYLIYTSGSTGAPKGVEVTHRNVASFLLAMARALPMGR
DDRLLATTTIGFDISLLELLLPPTVGAAVIACPEHMRIDAKALERVIADERVTWLQGTPSFFNVLRAGGWRGDKRLNILC
GGEPIDASTYGFLRETCAAVWQVYGPTEATIWSTIAGPDADGVEGLGEPLRNTTIHLLDAHGQQVPRFSKGEICIGGHGV
ARGYRHRAALSAERFVHVAGAGRVYRTGDFAFRDAHDRLRFLGREDGQVKIRGFRVELGEIERQIEALGGVRKAVVLVRR
ATAAEPTLIAWCEPHAGRALDADALRAALADALPAYMTPARIEPIDAWPLNANGKIDRGALAGRASAPQAPPLEPRDSVD
PLVPTLQAIYADVLRLDTVDPRATLMSLGGHSLSAVRIIARIQQQLKVDVGLETFMANSSVIGLIGSLRASGVPADGGSG
GAVAPGGDERSSPPEAAYAASRTSDTARRPATAADATPAPESNAASGCAPHVSPRTLQPSASEKALYFLDSVSAVRQTYN
IPVGLHFPEGVNADALERALRHVLDTHGALRAAFEPSADGLVKRMVPTPAGALIARHAPTDLATLVPTLNRMLREPFELH
EGPLMRAHHFPLEDGGAAVFYLFHHIIVDGIGCGNFLRELAGAYEALVGGMEPGGDGASSGDGNGNGNGNDNSDGDGDRQ
TNAAARVDELIERFGIVDRVLNLPYRAPFPEVRTLAGDSLPLEISAGLRAELDEYSRAAGVPLATLLLSAFVLTLHRLSG
DRTINVGLATMNRTPETLGKIGLYTNTIVLPVDIEPADRLGDFVDRVTAALFSIYGYADVPFEEVAGRLVEYASLGRTPV
FQAFFNFIDRSMYAFSMAGLPVREIALRPTGSKFELSLEVNDFRTHTQVFFEYSKDVFDEALVGDIASEFARTLLACVRS
PGDAVERFALTTQS
>Mature_1534_residues
MLQAVNDTLPLTNSQMAMWLQWKYAPDDPAYNNPLLFELDGDIDVERLKDAFAAVADAHPAIRMRFIERAGVPLQYSASH
PHGPLEFIDLSDVEPAARAPRIDAAIGACLLEPFDLLTEPVYRFVLVRTRPRGYLLALNIHHICVDGASALILLDDISSA
YADPAAYAAASAARTGEGFGDVLEVERRRWADGVHAQAETAWRAHLADRVCSVEFGKLAFDGERAAGGGAGQYRWTLPDT
LPAKIKAVNRLTRTTPFVVLMSAFGVLLHRYLQQDALAIAYPVDTRPAGFARIFGSFINFVPAFVDVSPDLTAGALFDKV
REQRRRTKAIADFPQVDLMRLARRTLADAALPCLNVALVPARFALDSLRFDGVRVEQRHCFTGAAKQDLALLYDGDETLS
LILEYRHGLLDEAIARRMAGDLNVIVERIVERPDLRLGDLTLSDHRAFAERYATLADAAPRTPALAAIERGWREQPERIV
AGEPGNAVSARQLLDASNRVARRLAAANVKPGERVGVRMDRGGALLAALVGIWKLGAVYVPLPTDLPGARRAHIADDAQL
AACLHRAEPADPTPRDLVLADDIFDASDAEALADFAVDPDSVAYLIYTSGSTGAPKGVEVTHRNVASFLLAMARALPMGR
DDRLLATTTIGFDISLLELLLPPTVGAAVIACPEHMRIDAKALERVIADERVTWLQGTPSFFNVLRAGGWRGDKRLNILC
GGEPIDASTYGFLRETCAAVWQVYGPTEATIWSTIAGPDADGVEGLGEPLRNTTIHLLDAHGQQVPRFSKGEICIGGHGV
ARGYRHRAALSAERFVHVAGAGRVYRTGDFAFRDAHDRLRFLGREDGQVKIRGFRVELGEIERQIEALGGVRKAVVLVRR
ATAAEPTLIAWCEPHAGRALDADALRAALADALPAYMTPARIEPIDAWPLNANGKIDRGALAGRASAPQAPPLEPRDSVD
PLVPTLQAIYADVLRLDTVDPRATLMSLGGHSLSAVRIIARIQQQLKVDVGLETFMANSSVIGLIGSLRASGVPADGGSG
GAVAPGGDERSSPPEAAYAASRTSDTARRPATAADATPAPESNAASGCAPHVSPRTLQPSASEKALYFLDSVSAVRQTYN
IPVGLHFPEGVNADALERALRHVLDTHGALRAAFEPSADGLVKRMVPTPAGALIARHAPTDLATLVPTLNRMLREPFELH
EGPLMRAHHFPLEDGGAAVFYLFHHIIVDGIGCGNFLRELAGAYEALVGGMEPGGDGASSGDGNGNGNGNDNSDGDGDRQ
TNAAARVDELIERFGIVDRVLNLPYRAPFPEVRTLAGDSLPLEISAGLRAELDEYSRAAGVPLATLLLSAFVLTLHRLSG
DRTINVGLATMNRTPETLGKIGLYTNTIVLPVDIEPADRLGDFVDRVTAALFSIYGYADVPFEEVAGRLVEYASLGRTPV
FQAFFNFIDRSMYAFSMAGLPVREIALRPTGSKFELSLEVNDFRTHTQVFFEYSKDVFDEALVGDIASEFARTLLACVRS
PGDAVERFALTTQS

Specific function: Activates the 7th to 12th amino acids (Val, D-Val, Trp, D-Leu, Xaa and D-Leu) in linear gramicidin and catalyzes the formation of the peptide bond between them. This enzyme is also responsible for the epimerization of the 8th (D-Val), the 10th (D- Leu) an

COG id: COG1020

COG function: function code Q; Non-ribosomal peptide synthetase modules and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 6 acyl carrier domains [H]

Homologues:

Organism=Homo sapiens, GI45580730, Length=594, Percent_Identity=22.7272727272727, Blast_Score=108, Evalue=3e-23,
Organism=Escherichia coli, GI1786801, Length=1081, Percent_Identity=26.5494912118409, Blast_Score=233, Evalue=7e-62,
Organism=Escherichia coli, GI1788107, Length=360, Percent_Identity=26.9444444444444, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17556356, Length=543, Percent_Identity=24.6777163904236, Blast_Score=124, Evalue=6e-28,
Organism=Caenorhabditis elegans, GI17550940, Length=448, Percent_Identity=26.1160714285714, Blast_Score=105, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI32564422, Length=355, Percent_Identity=24.7887323943662, Blast_Score=78, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI32564420, Length=355, Percent_Identity=24.7887323943662, Blast_Score=78, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6319591, Length=673, Percent_Identity=23.7741456166419, Blast_Score=131, Evalue=9e-31,
Organism=Drosophila melanogaster, GI24648676, Length=649, Percent_Identity=26.8104776579353, Blast_Score=164, Evalue=4e-40,
Organism=Drosophila melanogaster, GI24581924, Length=382, Percent_Identity=23.8219895287958, Blast_Score=78, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24582852, Length=459, Percent_Identity=23.5294117647059, Blast_Score=76, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010071
- InterPro:   IPR009081
- InterPro:   IPR020845
- InterPro:   IPR000873
- InterPro:   IPR023213
- InterPro:   IPR001242
- InterPro:   IPR010060
- InterPro:   IPR006163
- InterPro:   IPR020806
- InterPro:   IPR006162 [H]

Pfam domain/function: PF00501 AMP-binding; PF00668 Condensation; PF00550 PP-binding [H]

EC number: 2.7.7.- [C]

Molecular weight: Translated: 165332; Mature: 165332

Theoretical pI: Translated: 5.54; Mature: 5.54

Prosite motif: PS00012 PHOSPHOPANTETHEINE ; PS50075 ACP_DOMAIN ; PS00455 AMP_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLQAVNDTLPLTNSQMAMWLQWKYAPDDPAYNNPLLFELDGDIDVERLKDAFAAVADAHP
CCCCCCCCCCCCCCCEEEEEEEEECCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCH
AIRMRFIERAGVPLQYSASHPHGPLEFIDLSDVEPAARAPRIDAAIGACLLEPFDLLTEP
HHHHHHHHHCCCCEEECCCCCCCCEEEEECCCCCHHHCCCCHHHHHHHHHHCHHHHHHHH
VYRFVLVRTRPRGYLLALNIHHICVDGASALILLDDISSAYADPAAYAAASAARTGEGFG
HHHEEEEEECCCCEEEEEEEEEEEECCCCEEEEEECHHHHHCCHHHHHHHHHHHCCCCHH
DVLEVERRRWADGVHAQAETAWRAHLADRVCSVEFGKLAFDGERAAGGGAGQYRWTLPDT
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCCEEEECCCC
LPAKIKAVNRLTRTTPFVVLMSAFGVLLHRYLQQDALAIAYPVDTRPAGFARIFGSFINF
CHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCHHHHHHHHHHHH
VPAFVDVSPDLTAGALFDKVREQRRRTKAIADFPQVDLMRLARRTLADAALPCLNVALVP
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
ARFALDSLRFDGVRVEQRHCFTGAAKQDLALLYDGDETLSLILEYRHGLLDEAIARRMAG
HHHHHHHHCCCCEEEEHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCC
DLNVIVERIVERPDLRLGDLTLSDHRAFAERYATLADAAPRTPALAAIERGWREQPERIV
HHHHHHHHHHCCCCCEECCEEEHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCEEE
AGEPGNAVSARQLLDASNRVARRLAAANVKPGERVGVRMDRGGALLAALVGIWKLGAVYV
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCHHHHHHHHHHHHCEEEE
PLPTDLPGARRAHIADDAQLAACLHRAEPADPTPRDLVLADDIFDASDAEALADFAVDPD
ECCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCHHHHHHHCCCCC
SVAYLIYTSGSTGAPKGVEVTHRNVASFLLAMARALPMGRDDRLLATTTIGFDISLLELL
CEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCHHHHHHHH
LPPTVGAAVIACPEHMRIDAKALERVIADERVTWLQGTPSFFNVLRAGGWRGDKRLNILC
CCCCCCCEEEECCHHCEECHHHHHHHHHCCCEEEECCCHHHHHHHHHCCCCCCCEEEEEE
GGEPIDASTYGFLRETCAAVWQVYGPTEATIWSTIAGPDADGVEGLGEPLRNTTIHLLDA
CCCCCCCHHHHHHHHHHHHHHHHCCCCCHHEEEECCCCCCCCHHHHHHHHHCCEEEEEEC
HGQQVPRFSKGEICIGGHGVARGYRHRAALSAERFVHVAGAGRVYRTGDFAFRDAHDRLR
CCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHEEEEECCCCEEECCCCHHHHHHHHHH
FLGREDGQVKIRGFRVELGEIERQIEALGGVRKAVVLVRRATAAEPTLIAWCEPHAGRAL
HHCCCCCEEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCC
DADALRAALADALPAYMTPARIEPIDAWPLNANGKIDRGALAGRASAPQAPPLEPRDSVD
CHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PLVPTLQAIYADVLRLDTVDPRATLMSLGGHSLSAVRIIARIQQQLKVDVGLETFMANSS
HHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCHHHHHCCCC
VIGLIGSLRASGVPADGGSGGAVAPGGDERSSPPEAAYAASRTSDTARRPATAADATPAP
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCHHCCCCCCCCCCCCC
ESNAASGCAPHVSPRTLQPSASEKALYFLDSVSAVRQTYNIPVGLHFPEGVNADALERAL
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHH
RHVLDTHGALRAAFEPSADGLVKRMVPTPAGALIARHAPTDLATLVPTLNRMLREPFELH
HHHHHCCHHHHCCCCCCHHHHHHHHCCCCCHHHHCCCCCCHHHHHHHHHHHHHHCHHHHC
EGPLMRAHHFPLEDGGAAVFYLFHHIIVDGIGCGNFLRELAGAYEALVGGMEPGGDGASS
CCCCCEEECCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCC
GDGNGNGNGNDNSDGDGDRQTNAAARVDELIERFGIVDRVLNLPYRAPFPEVRTLAGDSL
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCCC
PLEISAGLRAELDEYSRAAGVPLATLLLSAFVLTLHRLSGDRTINVGLATMNRTPETLGK
CEEECCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCHHHHHH
IGLYTNTIVLPVDIEPADRLGDFVDRVTAALFSIYGYADVPFEEVAGRLVEYASLGRTPV
HCEEECEEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCHH
FQAFFNFIDRSMYAFSMAGLPVREIALRPTGSKFELSLEVNDFRTHTQVFFEYSKDVFDE
HHHHHHHHHHHHHHHHHCCCCHHHEEECCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHH
ALVGDIASEFARTLLACVRSPGDAVERFALTTQS
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCC
>Mature Secondary Structure
MLQAVNDTLPLTNSQMAMWLQWKYAPDDPAYNNPLLFELDGDIDVERLKDAFAAVADAHP
CCCCCCCCCCCCCCCEEEEEEEEECCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCH
AIRMRFIERAGVPLQYSASHPHGPLEFIDLSDVEPAARAPRIDAAIGACLLEPFDLLTEP
HHHHHHHHHCCCCEEECCCCCCCCEEEEECCCCCHHHCCCCHHHHHHHHHHCHHHHHHHH
VYRFVLVRTRPRGYLLALNIHHICVDGASALILLDDISSAYADPAAYAAASAARTGEGFG
HHHEEEEEECCCCEEEEEEEEEEEECCCCEEEEEECHHHHHCCHHHHHHHHHHHCCCCHH
DVLEVERRRWADGVHAQAETAWRAHLADRVCSVEFGKLAFDGERAAGGGAGQYRWTLPDT
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCCEEEECCCC
LPAKIKAVNRLTRTTPFVVLMSAFGVLLHRYLQQDALAIAYPVDTRPAGFARIFGSFINF
CHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCHHHHHHHHHHHH
VPAFVDVSPDLTAGALFDKVREQRRRTKAIADFPQVDLMRLARRTLADAALPCLNVALVP
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
ARFALDSLRFDGVRVEQRHCFTGAAKQDLALLYDGDETLSLILEYRHGLLDEAIARRMAG
HHHHHHHHCCCCEEEEHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCC
DLNVIVERIVERPDLRLGDLTLSDHRAFAERYATLADAAPRTPALAAIERGWREQPERIV
HHHHHHHHHHCCCCCEECCEEEHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCEEE
AGEPGNAVSARQLLDASNRVARRLAAANVKPGERVGVRMDRGGALLAALVGIWKLGAVYV
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCHHHHHHHHHHHHCEEEE
PLPTDLPGARRAHIADDAQLAACLHRAEPADPTPRDLVLADDIFDASDAEALADFAVDPD
ECCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCHHHHHHHCCCCC
SVAYLIYTSGSTGAPKGVEVTHRNVASFLLAMARALPMGRDDRLLATTTIGFDISLLELL
CEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCHHHHHHHH
LPPTVGAAVIACPEHMRIDAKALERVIADERVTWLQGTPSFFNVLRAGGWRGDKRLNILC
CCCCCCCEEEECCHHCEECHHHHHHHHHCCCEEEECCCHHHHHHHHHCCCCCCCEEEEEE
GGEPIDASTYGFLRETCAAVWQVYGPTEATIWSTIAGPDADGVEGLGEPLRNTTIHLLDA
CCCCCCCHHHHHHHHHHHHHHHHCCCCCHHEEEECCCCCCCCHHHHHHHHHCCEEEEEEC
HGQQVPRFSKGEICIGGHGVARGYRHRAALSAERFVHVAGAGRVYRTGDFAFRDAHDRLR
CCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHEEEEECCCCEEECCCCHHHHHHHHHH
FLGREDGQVKIRGFRVELGEIERQIEALGGVRKAVVLVRRATAAEPTLIAWCEPHAGRAL
HHCCCCCEEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCC
DADALRAALADALPAYMTPARIEPIDAWPLNANGKIDRGALAGRASAPQAPPLEPRDSVD
CHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PLVPTLQAIYADVLRLDTVDPRATLMSLGGHSLSAVRIIARIQQQLKVDVGLETFMANSS
HHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCHHHHHCCCC
VIGLIGSLRASGVPADGGSGGAVAPGGDERSSPPEAAYAASRTSDTARRPATAADATPAP
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCHHCCCCCCCCCCCCC
ESNAASGCAPHVSPRTLQPSASEKALYFLDSVSAVRQTYNIPVGLHFPEGVNADALERAL
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHH
RHVLDTHGALRAAFEPSADGLVKRMVPTPAGALIARHAPTDLATLVPTLNRMLREPFELH
HHHHHCCHHHHCCCCCCHHHHHHHHCCCCCHHHHCCCCCCHHHHHHHHHHHHHHCHHHHC
EGPLMRAHHFPLEDGGAAVFYLFHHIIVDGIGCGNFLRELAGAYEALVGGMEPGGDGASS
CCCCCEEECCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCC
GDGNGNGNGNDNSDGDGDRQTNAAARVDELIERFGIVDRVLNLPYRAPFPEVRTLAGDSL
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCCC
PLEISAGLRAELDEYSRAAGVPLATLLLSAFVLTLHRLSGDRTINVGLATMNRTPETLGK
CEEECCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCHHHHHH
IGLYTNTIVLPVDIEPADRLGDFVDRVTAALFSIYGYADVPFEEVAGRLVEYASLGRTPV
HCEEECEEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCHH
FQAFFNFIDRSMYAFSMAGLPVREIALRPTGSKFELSLEVNDFRTHTQVFFEYSKDVFDE
HHHHHHHHHHHHHHHHHCCCCHHHEEECCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHH
ALVGDIASEFARTLLACVRSPGDAVERFALTTQS
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Phosphopantetheine. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 6 ATP; L-serine; 2,3-dihydroxybenzoate [C]

Specific reaction: 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Seryl-AMP 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Ser

General reaction: Transferases; Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA