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The map label for this gene is nudF [H]

Identifier: 126442640

GI number: 126442640

Start: 1498629

End: 1499105

Strand: Reverse

Name: nudF [H]

Synonym: BURPS668_A1565

Alternate gene names: 126442640

Gene position: 1499105-1498629 (Counterclockwise)

Preceding gene: 126444871

Following gene: 126443438

Centisome position: 47.93

GC content: 71.07

Gene sequence:

>477_bases
ATGACTGATCCGAAAGGCACGGGCGACGCGGCGCTCGCGACACCGCGCGTCGCGGTGATCGCCGTCACGTTTCGCGGCGA
CGACGTGATCCTCGTGCGGCGCGGCAAGGAACCGCAGAAGGGCACATGGGGCTTTCCCGGCGGCTCGGTGGAGCCCGGCG
AATGCCTGCGCGAGGCGGCCGCGCGCGAGCTGTTCGAGGAGACCGGCGTGCGCGCGGAGGTGGGCGAGCCGTTCGATGTC
GTCGAGGTGATCGGCTTCGATCCGCACGGCCGGCATCACCACTACGTGCTCGTCGCGATGCTGTGCCGCCATGTCGAAGG
CGCGCTGCGGCCGGGCGACGACGCGACGGACTGCCGCTGGGTTCGCGTGCCGGCCGACCTGTCTCGATTCCCCGGCGCGC
TCGCGGACCACGTCGCGCGCGTCGCGCAGCGGGCGCACGCCCTCAATCATCCCAACCGAAAGGAAAACAGCCGATGA

Upstream 100 bases:

>100_bases
TCATTCATTAACCATGGAGGCGGCCAATGGCCGTCGATTGGCGCGCCGGGGCCGAACGAACGGCGCGCGAAGACAGGGGC
GCGGATGTGGAGCATCGACG

Downstream 100 bases:

>100_bases
AGCGCATGTTCTTGGGCGGACCGTTCAAATCCCTGGTCGACAAGCAGACCGGCGTGATGCCGGAAGGCAGCATCAACCTG
TTTCGCCGCGTGATCGATCA

Product: ADP-ribose pyrophosphatase

Products: NA

Alternate protein names: ADP-ribose diphosphatase; ADP-ribose phosphohydrolase; Adenosine diphosphoribose pyrophosphatase; ADPR-PPase [H]

Number of amino acids: Translated: 158; Mature: 157

Protein sequence:

>158_residues
MTDPKGTGDAALATPRVAVIAVTFRGDDVILVRRGKEPQKGTWGFPGGSVEPGECLREAAARELFEETGVRAEVGEPFDV
VEVIGFDPHGRHHHYVLVAMLCRHVEGALRPGDDATDCRWVRVPADLSRFPGALADHVARVAQRAHALNHPNRKENSR

Sequences:

>Translated_158_residues
MTDPKGTGDAALATPRVAVIAVTFRGDDVILVRRGKEPQKGTWGFPGGSVEPGECLREAAARELFEETGVRAEVGEPFDV
VEVIGFDPHGRHHHYVLVAMLCRHVEGALRPGDDATDCRWVRVPADLSRFPGALADHVARVAQRAHALNHPNRKENSR
>Mature_157_residues
TDPKGTGDAALATPRVAVIAVTFRGDDVILVRRGKEPQKGTWGFPGGSVEPGECLREAAARELFEETGVRAEVGEPFDVV
EVIGFDPHGRHHHYVLVAMLCRHVEGALRPGDDATDCRWVRVPADLSRFPGALADHVARVAQRAHALNHPNRKENSR

Specific function: Specific For Pyrimidine Substrates. Acts On 5-Methyl- Dctp, Ctp And Dctp In Decreasing Order. [C]

COG id: COG1051

COG function: function code F; ADP-ribose pyrophosphatase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020476
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: =3.6.1.13 [H]

Molecular weight: Translated: 17244; Mature: 17112

Theoretical pI: Translated: 6.95; Mature: 6.95

Prosite motif: PS00893 NUDIX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDPKGTGDAALATPRVAVIAVTFRGDDVILVRRGKEPQKGTWGFPGGSVEPGECLREAA
CCCCCCCCCCCCCCCCEEEEEEEECCCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHH
ARELFEETGVRAEVGEPFDVVEVIGFDPHGRHHHYVLVAMLCRHVEGALRPGDDATDCRW
HHHHHHHCCCCCCCCCCCCCHHEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCEE
VRVPADLSRFPGALADHVARVAQRAHALNHPNRKENSR
EECCCCHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
TDPKGTGDAALATPRVAVIAVTFRGDDVILVRRGKEPQKGTWGFPGGSVEPGECLREAA
CCCCCCCCCCCCCCCEEEEEEEECCCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHH
ARELFEETGVRAEVGEPFDVVEVIGFDPHGRHHHYVLVAMLCRHVEGALRPGDDATDCRW
HHHHHHHCCCCCCCCCCCCCHHEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCEE
VRVPADLSRFPGALADHVARVAQRAHALNHPNRKENSR
EECCCCHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087; 9694840 [H]