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The map label for this gene is aphA [H]

Identifier: 126442556

GI number: 126442556

Start: 1881030

End: 1883201

Strand: Reverse

Name: aphA [H]

Synonym: BURPS668_A1934

Alternate gene names: 126442556

Gene position: 1883201-1881030 (Counterclockwise)

Preceding gene: 126444002

Following gene: 126443363

Centisome position: 60.22

GC content: 67.68

Gene sequence:

>2172_bases
ATGGCGTCGGGCATCGGGCGATTCGGGAAAAGAGCGTCGCGCTTGATCGATTTCGGTTTGTGGGCCGCCGCCGCGCTGTT
ACTGCTGACGGCGGGCGTCGGCGCGCTCGGCACGGCCCGCCTGTCCGACAACGAGGCGGATATCCATCGCGCGAGCGAGG
TGATATCGGGTCTCGAACGGCTGCTGGCGCTGGCCCGCGACATGGAGACGAGCCAGCGCGGATATATCCTCACCGGCAAG
ACGGACTACCTTCAGCCCTACAAGGCGGCACTGCCCGAAATCCGCAAGCAGTTCGACGCGCTCGCGACGCTTGTGCAGGG
CGATGCCGTTCAGCAGCAGCGGCTCGCGACGCTGCGCATGCTGCTCGAGAAAAAGCAGCACGAGCTCGCGGCGACGATCG
AGCTGCGCAAGACGGAGGGGTTCGACGCGGCGCAGGCGATCGTCTCGAGCGATGCGGGCAAGATCTTCATGGACCGCGCG
CGCGTGATGGTCAACGAAATGGAGGCGACCGTCCAGCAGCAACTGAGGACGCTGCGCGATCGCGCCAGGGCGACACGCGA
CATCGCGATCGGCGTGGGGCTCGCCTCCGGGCTGCTCACGCTCGCCGTGTGCGTATCGTTCGGCTATGTGATGCGCCGCC
TGCTGCTCGTCGAGGCGGCCGCGGCCCACGATCTGTTCGAGCAGCGCGAACTGCTGCACGTGACGCTCGCGAGCATCGGC
GACGGCGTGATCGCGACGGACGTCGGCGGCCGCATCACGTTCTTCAACCGGGTCGCCGAGGAGATGACGGCGCTTTGCAC
CGATGCCGTCGTCGGTCAGCCGATCGAGCAGGTGCTGACTTTTCGGCATGCCGCGACGCAGCGGGTGATCGACAATCCGG
CGCGCGTCGCGGTCGAGCGCAGGCGCACCGCGAGCTTGCCCCCCCATACGCGCTTCGTCGGCCGCAGCGGTGGGGAATTG
CCGGTGGACGGCAACGCCGCACCGACGTTCGACGCGAACGGCAAGCTCGTCGGCGCGGTGCTCGTCGTGCGCGACGTGTC
GGAGCGCGAGCGGGCCGAGGAGCGATTCCGGCTCGCCGTCGAGGCTGCGCCGACCGCGATGATCATGGTGGGGCGCGACG
GCAGGATCGTGCTCGTCAATTCGCAGGCCGAGAAATTGTTCGGGTACGCGCGCGGCGACATGATCGGGCACGGCATCGAC
ATGCTGGTGCCCGAGCGTTTTCGTGCGGGGCATTGGGCGCACCGCGACGCGTTCTTCGGCAGCCCGGACGCGCGGCCGAT
GGGCGAGGGGCGGGACCTGTTCGGTTTGCGCCGCGACGGCAGCGAGTTTCCGGTCGAGATCGGCCTGAATCCGATCACGA
CCTCGGAGGGCGCGTTCGTGCTGTGCTCGATCGCCGACATCACCGCGCGCAAGCGCGCGGAACTCGAACTGCGCCGCAGA
AGCGAGGAGCTTGCGCGCTCGAATCAGGATCTCGAGCAGTTCGCCTACGTCGCGTCTCACGATCTGCAGGAGCCGTTGCG
AGCGGTCGCGGGGCCTCTGCAATTGCTGCAGCGGCGATACCAGGGGCAGCTCGACGCGCGGGCCGACGAGTTCATCGGGC
ACGCGGTGGATGGCGCGACGAGAATGCAGTCGCTGATCGACGACCTGCTCAGCTATTCGCGCGTCGGGCGGCTCGAGGAC
GCGCGTCGGCCGGTCGACTGCGAGCACGTGCTGGACGAGGCGCTGCGCAACCTGAGCGCGGCGATTCGCGAATCCGGCGC
GCAGGTCACGCACGATCCGCTGCCGACCGTGCATGGCATCGAGGCACAGCTCGTGCTGCTGTTCCAGAATCTGATCGGCA
ACGCGATCAAGTTTCGCGGCAAGGACCGCGTCGCGCGGATTCATCTGGAAGCGCACACGCGCGACGACGCATGGCTGTTG
CGCGTGCGCGACAACGGCATCGGGATCGATCCCCAGTATTTCGAGCGCATCTTCCTGATTTTCCAGCGGCTGCACACGCG
GCGCGAATATCCGGGAACGGGGCTCGGGCTCGCGCTGTGCAAGCGGATCGTCGAGCACCATGGCGGCCGCATCTTCGTCG
AGTCCGAGCCGGGGCAGGGCACGACGTTTTCGTTTACGCTGTCCAGGCCGGGTGCCGATGAAACGCGTTGGCCGCGCGAT
CCGAGGGAGTGA

Upstream 100 bases:

>100_bases
CCGGCGTGCGCGCCGGCGCGCGGCGAGCCGGGCGGCGGCCGCATCCCGCGATCAAGCTTGCAAACGGCTTTCTGGCAAAG
ACACCTCGGAGGGGGGCGAG

Downstream 100 bases:

>100_bases
GCGATGATTGCCGATGAGCGAGGAAATTTCGTCGAGATCCTGCTGGTCGAGGACAGCCCGACCGACGTGATGATGACCAA
GGAGGCGCTCGAATACTACA

Product: two-component sensor kinase protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 723; Mature: 722

Protein sequence:

>723_residues
MASGIGRFGKRASRLIDFGLWAAAALLLLTAGVGALGTARLSDNEADIHRASEVISGLERLLALARDMETSQRGYILTGK
TDYLQPYKAALPEIRKQFDALATLVQGDAVQQQRLATLRMLLEKKQHELAATIELRKTEGFDAAQAIVSSDAGKIFMDRA
RVMVNEMEATVQQQLRTLRDRARATRDIAIGVGLASGLLTLAVCVSFGYVMRRLLLVEAAAAHDLFEQRELLHVTLASIG
DGVIATDVGGRITFFNRVAEEMTALCTDAVVGQPIEQVLTFRHAATQRVIDNPARVAVERRRTASLPPHTRFVGRSGGEL
PVDGNAAPTFDANGKLVGAVLVVRDVSERERAEERFRLAVEAAPTAMIMVGRDGRIVLVNSQAEKLFGYARGDMIGHGID
MLVPERFRAGHWAHRDAFFGSPDARPMGEGRDLFGLRRDGSEFPVEIGLNPITTSEGAFVLCSIADITARKRAELELRRR
SEELARSNQDLEQFAYVASHDLQEPLRAVAGPLQLLQRRYQGQLDARADEFIGHAVDGATRMQSLIDDLLSYSRVGRLED
ARRPVDCEHVLDEALRNLSAAIRESGAQVTHDPLPTVHGIEAQLVLLFQNLIGNAIKFRGKDRVARIHLEAHTRDDAWLL
RVRDNGIGIDPQYFERIFLIFQRLHTRREYPGTGLGLALCKRIVEHHGGRIFVESEPGQGTTFSFTLSRPGADETRWPRD
PRE

Sequences:

>Translated_723_residues
MASGIGRFGKRASRLIDFGLWAAAALLLLTAGVGALGTARLSDNEADIHRASEVISGLERLLALARDMETSQRGYILTGK
TDYLQPYKAALPEIRKQFDALATLVQGDAVQQQRLATLRMLLEKKQHELAATIELRKTEGFDAAQAIVSSDAGKIFMDRA
RVMVNEMEATVQQQLRTLRDRARATRDIAIGVGLASGLLTLAVCVSFGYVMRRLLLVEAAAAHDLFEQRELLHVTLASIG
DGVIATDVGGRITFFNRVAEEMTALCTDAVVGQPIEQVLTFRHAATQRVIDNPARVAVERRRTASLPPHTRFVGRSGGEL
PVDGNAAPTFDANGKLVGAVLVVRDVSERERAEERFRLAVEAAPTAMIMVGRDGRIVLVNSQAEKLFGYARGDMIGHGID
MLVPERFRAGHWAHRDAFFGSPDARPMGEGRDLFGLRRDGSEFPVEIGLNPITTSEGAFVLCSIADITARKRAELELRRR
SEELARSNQDLEQFAYVASHDLQEPLRAVAGPLQLLQRRYQGQLDARADEFIGHAVDGATRMQSLIDDLLSYSRVGRLED
ARRPVDCEHVLDEALRNLSAAIRESGAQVTHDPLPTVHGIEAQLVLLFQNLIGNAIKFRGKDRVARIHLEAHTRDDAWLL
RVRDNGIGIDPQYFERIFLIFQRLHTRREYPGTGLGLALCKRIVEHHGGRIFVESEPGQGTTFSFTLSRPGADETRWPRD
PRE
>Mature_722_residues
ASGIGRFGKRASRLIDFGLWAAAALLLLTAGVGALGTARLSDNEADIHRASEVISGLERLLALARDMETSQRGYILTGKT
DYLQPYKAALPEIRKQFDALATLVQGDAVQQQRLATLRMLLEKKQHELAATIELRKTEGFDAAQAIVSSDAGKIFMDRAR
VMVNEMEATVQQQLRTLRDRARATRDIAIGVGLASGLLTLAVCVSFGYVMRRLLLVEAAAAHDLFEQRELLHVTLASIGD
GVIATDVGGRITFFNRVAEEMTALCTDAVVGQPIEQVLTFRHAATQRVIDNPARVAVERRRTASLPPHTRFVGRSGGELP
VDGNAAPTFDANGKLVGAVLVVRDVSERERAEERFRLAVEAAPTAMIMVGRDGRIVLVNSQAEKLFGYARGDMIGHGIDM
LVPERFRAGHWAHRDAFFGSPDARPMGEGRDLFGLRRDGSEFPVEIGLNPITTSEGAFVLCSIADITARKRAELELRRRS
EELARSNQDLEQFAYVASHDLQEPLRAVAGPLQLLQRRYQGQLDARADEFIGHAVDGATRMQSLIDDLLSYSRVGRLEDA
RRPVDCEHVLDEALRNLSAAIRESGAQVTHDPLPTVHGIEAQLVLLFQNLIGNAIKFRGKDRVARIHLEAHTRDDAWLLR
VRDNGIGIDPQYFERIFLIFQRLHTRREYPGTGLGLALCKRIVEHHGGRIFVESEPGQGTTFSFTLSRPGADETRWPRDP
RE

Specific function: Photoreceptor which exists in two forms that are reversibly interconvertible by light:the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI145693157, Length=260, Percent_Identity=28.8461538461538, Blast_Score=103, Evalue=5e-23,
Organism=Escherichia coli, GI48994928, Length=260, Percent_Identity=29.2307692307692, Blast_Score=95, Evalue=2e-20,
Organism=Escherichia coli, GI1786912, Length=242, Percent_Identity=32.6446280991736, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI1788549, Length=375, Percent_Identity=27.4666666666667, Blast_Score=90, Evalue=5e-19,
Organism=Escherichia coli, GI1789149, Length=251, Percent_Identity=28.6852589641434, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1786600, Length=371, Percent_Identity=27.4932614555256, Blast_Score=79, Evalue=7e-16,
Organism=Escherichia coli, GI87081816, Length=241, Percent_Identity=26.5560165975104, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1788393, Length=245, Percent_Identity=28.5714285714286, Blast_Score=73, Evalue=6e-14,
Organism=Escherichia coli, GI1788713, Length=261, Percent_Identity=24.5210727969349, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI1788381, Length=127, Percent_Identity=31.496062992126, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1790436, Length=242, Percent_Identity=28.5123966942149, Blast_Score=70, Evalue=5e-13,
Organism=Escherichia coli, GI1790861, Length=224, Percent_Identity=28.5714285714286, Blast_Score=67, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003018
- InterPro:   IPR013654
- InterPro:   IPR016132
- InterPro:   IPR001294
- InterPro:   IPR013515
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF01590 GAF; PF02518 HATPase_c; PF00512 HisKA; PF08446 PAS_2; PF00360 Phytochrome [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 79947; Mature: 79816

Theoretical pI: Translated: 7.35; Mature: 7.35

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASGIGRFGKRASRLIDFGLWAAAALLLLTAGVGALGTARLSDNEADIHRASEVISGLER
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCHHHHHHHHHHHHHHHH
LLALARDMETSQRGYILTGKTDYLQPYKAALPEIRKQFDALATLVQGDAVQQQRLATLRM
HHHHHHHCCCCCCCEEEECCCHHCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
LLEKKQHELAATIELRKTEGFDAAQAIVSSDAGKIFMDRARVMVNEMEATVQQQLRTLRD
HHHHHHHHHHHHEEEECCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
RARATRDIAIGVGLASGLLTLAVCVSFGYVMRRLLLVEAAAAHDLFEQRELLHVTLASIG
HHHHHHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DGVIATDVGGRITFFNRVAEEMTALCTDAVVGQPIEQVLTFRHAATQRVIDNPARVAVER
CCEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHH
RRTASLPPHTRFVGRSGGELPVDGNAAPTFDANGKLVGAVLVVRDVSERERAEERFRLAV
HHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEHHHHHHCCHHHHHHHHHHHHHH
EAAPTAMIMVGRDGRIVLVNSQAEKLFGYARGDMIGHGIDMLVPERFRAGHWAHRDAFFG
CCCCEEEEEECCCCEEEEECCCHHHHHHHHHCCHHHCCHHHHCCHHHHCCCCHHCCCCCC
SPDARPMGEGRDLFGLRRDGSEFPVEIGLNPITTSEGAFVLCSIADITARKRAELELRRR
CCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHH
SEELARSNQDLEQFAYVASHDLQEPLRAVAGPLQLLQRRYQGQLDARADEFIGHAVDGAT
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
RMQSLIDDLLSYSRVGRLEDARRPVDCEHVLDEALRNLSAAIRESGAQVTHDPLPTVHGI
HHHHHHHHHHHHHHCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
EAQLVLLFQNLIGNAIKFRGKDRVARIHLEAHTRDDAWLLRVRDNGIGIDPQYFERIFLI
HHHHHHHHHHHHHHHHEECCCCCEEEEEEEEECCCCEEEEEEECCCCCCCHHHHHHHHHH
FQRLHTRREYPGTGLGLALCKRIVEHHGGRIFVESEPGQGTTFSFTLSRPGADETRWPRD
HHHHHHHCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCEEEEEECCCCCCCCCCCCC
PRE
CCC
>Mature Secondary Structure 
ASGIGRFGKRASRLIDFGLWAAAALLLLTAGVGALGTARLSDNEADIHRASEVISGLER
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCHHHHHHHHHHHHHHHH
LLALARDMETSQRGYILTGKTDYLQPYKAALPEIRKQFDALATLVQGDAVQQQRLATLRM
HHHHHHHCCCCCCCEEEECCCHHCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
LLEKKQHELAATIELRKTEGFDAAQAIVSSDAGKIFMDRARVMVNEMEATVQQQLRTLRD
HHHHHHHHHHHHEEEECCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
RARATRDIAIGVGLASGLLTLAVCVSFGYVMRRLLLVEAAAAHDLFEQRELLHVTLASIG
HHHHHHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DGVIATDVGGRITFFNRVAEEMTALCTDAVVGQPIEQVLTFRHAATQRVIDNPARVAVER
CCEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHH
RRTASLPPHTRFVGRSGGELPVDGNAAPTFDANGKLVGAVLVVRDVSERERAEERFRLAV
HHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEHHHHHHCCHHHHHHHHHHHHHH
EAAPTAMIMVGRDGRIVLVNSQAEKLFGYARGDMIGHGIDMLVPERFRAGHWAHRDAFFG
CCCCEEEEEECCCCEEEEECCCHHHHHHHHHCCHHHCCHHHHCCHHHHCCCCHHCCCCCC
SPDARPMGEGRDLFGLRRDGSEFPVEIGLNPITTSEGAFVLCSIADITARKRAELELRRR
CCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHH
SEELARSNQDLEQFAYVASHDLQEPLRAVAGPLQLLQRRYQGQLDARADEFIGHAVDGAT
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
RMQSLIDDLLSYSRVGRLEDARRPVDCEHVLDEALRNLSAAIRESGAQVTHDPLPTVHGI
HHHHHHHHHHHHHHCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
EAQLVLLFQNLIGNAIKFRGKDRVARIHLEAHTRDDAWLLRVRDNGIGIDPQYFERIFLI
HHHHHHHHHHHHHHHHEECCCCCEEEEEEEEECCCCEEEEEEECCCCCCCHHHHHHHHHH
FQRLHTRREYPGTGLGLALCKRIVEHHGGRIFVESEPGQGTTFSFTLSRPGADETRWPRD
HHHHHHHCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCEEEEEECCCCCCCCCCCCC
PRE
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11759840 [H]