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The map label for this gene is fabD [H]

Identifier: 126209447

GI number: 126209447

Start: 2219340

End: 2220275

Strand: Reverse

Name: fabD [H]

Synonym: APL_1993

Alternate gene names: 126209447

Gene position: 2220275-2219340 (Counterclockwise)

Preceding gene: 126209448

Following gene: 126209446

Centisome position: 97.62

GC content: 45.09

Gene sequence:

>936_bases
ATGTCAAATTTTGCAATGGTGTTCCCGGGACAGGGCTCACAAGCGGTCGGAATGTTAGCGGATCTTGCAACCGCATACCC
AATTGTTGAAGAAACCTTCAAACAAGCATCTGATGTTTTAGGTTACGATCTTTGGGATCTCGTACAAAACGGTTCGGCGG
AAGATTTAGGTCAAACACAACGTACCCAACCGGCGCTTTTAGCTTCATCGGTTGCGATTTATCGTGTGTGGCAACAAAAA
TACCCTGAATTAAAACCGTCTGTCATGGCAGGTCATAGCTTAGGCGAATACTCGGCATTAGTTTGTGCTGGCGTATTAGA
TTTCCAAGATGCGATCAAACTAGTGGAATTACGTGGTAATGCAATGCAACAAGCAGTACCGGCGGGTACAGGCGCAATGT
ATGCGATTATCGGCTTAGATAACGAAGCGATTATTAACGCTTGTGAACAAGCTCAAGCGGAAGTCGGCGAAATCGTTTCA
GCAGTAAACTTCAATAGCCCGGGTCAAGTCGTGATTGCCGGTACAAAAGCGGCTGCGGAAAAAGCGGGTGAATTATGTAA
AGCGGCAGGCGCAAAACGTGCGTTACCACTTGCGGTAAGCGTACCGTCTCACTGTGCATTAATGAAACCGGCTGCGGATA
AATTAGCCGAAGCATTACAAAATATCACGTTAAACGTACCGGTTGTACCAGTTATTAACAATGTTGATGTTAGTGTAGAA
ACGGATGCAGAAGCCATTCGTAACGCATTAGTTCGCCAACTTTATAGCCCGGTTCGTTGGACTGAAACGGTAGAAAAAAT
GGCGAATCAAGGTGTTACAACGCTTTATGAAATCGGCTCGGGTAAAGTCTTAACCGGTTTAGCTGGTCGTATCGTAAAAG
AGTTAAATGCCAAAGCAGTCAATGATGTAGCTTCATTAGAGGCTGTTTCAGCATAA

Upstream 100 bases:

>100_bases
TGAAATCGGTAAACTTTATTATTCACCGGATTAAGCATTATTCATAACGGACGCTCTTAGTGCGTCCTCAGCACCAAATT
TATAAATAAGAGGAAAAAAT

Downstream 100 bases:

>100_bases
TGATTAACTCCCCTCTTTGAAAAGAGGGGCTGGGGGAGATTTTTAGGATCTTCAACATCACACTTATCTCCCCTCCCCCT
CCTTATTAAAGGGGGGGAAC

Product: malonyl CoA-acyl carrier protein transacylase (MCT)

Products: NA

Alternate protein names: MCT [H]

Number of amino acids: Translated: 311; Mature: 310

Protein sequence:

>311_residues
MSNFAMVFPGQGSQAVGMLADLATAYPIVEETFKQASDVLGYDLWDLVQNGSAEDLGQTQRTQPALLASSVAIYRVWQQK
YPELKPSVMAGHSLGEYSALVCAGVLDFQDAIKLVELRGNAMQQAVPAGTGAMYAIIGLDNEAIINACEQAQAEVGEIVS
AVNFNSPGQVVIAGTKAAAEKAGELCKAAGAKRALPLAVSVPSHCALMKPAADKLAEALQNITLNVPVVPVINNVDVSVE
TDAEAIRNALVRQLYSPVRWTETVEKMANQGVTTLYEIGSGKVLTGLAGRIVKELNAKAVNDVASLEAVSA

Sequences:

>Translated_311_residues
MSNFAMVFPGQGSQAVGMLADLATAYPIVEETFKQASDVLGYDLWDLVQNGSAEDLGQTQRTQPALLASSVAIYRVWQQK
YPELKPSVMAGHSLGEYSALVCAGVLDFQDAIKLVELRGNAMQQAVPAGTGAMYAIIGLDNEAIINACEQAQAEVGEIVS
AVNFNSPGQVVIAGTKAAAEKAGELCKAAGAKRALPLAVSVPSHCALMKPAADKLAEALQNITLNVPVVPVINNVDVSVE
TDAEAIRNALVRQLYSPVRWTETVEKMANQGVTTLYEIGSGKVLTGLAGRIVKELNAKAVNDVASLEAVSA
>Mature_310_residues
SNFAMVFPGQGSQAVGMLADLATAYPIVEETFKQASDVLGYDLWDLVQNGSAEDLGQTQRTQPALLASSVAIYRVWQQKY
PELKPSVMAGHSLGEYSALVCAGVLDFQDAIKLVELRGNAMQQAVPAGTGAMYAIIGLDNEAIINACEQAQAEVGEIVSA
VNFNSPGQVVIAGTKAAAEKAGELCKAAGAKRALPLAVSVPSHCALMKPAADKLAEALQNITLNVPVVPVINNVDVSVET
DAEAIRNALVRQLYSPVRWTETVEKMANQGVTTLYEIGSGKVLTGLAGRIVKELNAKAVNDVASLEAVSA

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Homo sapiens, GI51243059, Length=320, Percent_Identity=32.1875, Blast_Score=150, Evalue=1e-36,
Organism=Homo sapiens, GI27477045, Length=111, Percent_Identity=43.2432432432432, Blast_Score=80, Evalue=2e-15,
Organism=Escherichia coli, GI1787334, Length=308, Percent_Identity=68.8311688311688, Blast_Score=399, Evalue=1e-112,
Organism=Caenorhabditis elegans, GI71984332, Length=293, Percent_Identity=32.7645051194539, Blast_Score=135, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI17550940, Length=301, Percent_Identity=29.2358803986711, Blast_Score=99, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24665753, Length=306, Percent_Identity=33.9869281045752, Blast_Score=144, Evalue=7e-35,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 32655; Mature: 32523

Theoretical pI: Translated: 4.51; Mature: 4.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNFAMVFPGQGSQAVGMLADLATAYPIVEETFKQASDVLGYDLWDLVQNGSAEDLGQTQ
CCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCHHHHHHHH
RTQPALLASSVAIYRVWQQKYPELKPSVMAGHSLGEYSALVCAGVLDFQDAIKLVELRGN
CCCHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCH
AMQQAVPAGTGAMYAIIGLDNEAIINACEQAQAEVGEIVSAVNFNSPGQVVIAGTKAAAE
HHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCHHHHH
KAGELCKAAGAKRALPLAVSVPSHCALMKPAADKLAEALQNITLNVPVVPVINNVDVSVE
HHHHHHHHCCCCCCCEEEEECCCCHHHCCHHHHHHHHHHHCCCCCCCEEEEECCCCEEEE
TDAEAIRNALVRQLYSPVRWTETVEKMANQGVTTLYEIGSGKVLTGLAGRIVKELNAKAV
CCHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHHHH
NDVASLEAVSA
HHHHHHHHHCC
>Mature Secondary Structure 
SNFAMVFPGQGSQAVGMLADLATAYPIVEETFKQASDVLGYDLWDLVQNGSAEDLGQTQ
CCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCHHHHHHHH
RTQPALLASSVAIYRVWQQKYPELKPSVMAGHSLGEYSALVCAGVLDFQDAIKLVELRGN
CCCHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCH
AMQQAVPAGTGAMYAIIGLDNEAIINACEQAQAEVGEIVSAVNFNSPGQVVIAGTKAAAE
HHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCHHHHH
KAGELCKAAGAKRALPLAVSVPSHCALMKPAADKLAEALQNITLNVPVVPVINNVDVSVE
HHHHHHHHCCCCCCCEEEEECCCCHHHCCHHHHHHHHHHHCCCCCCCEEEEECCCCEEEE
TDAEAIRNALVRQLYSPVRWTETVEKMANQGVTTLYEIGSGKVLTGLAGRIVKELNAKAV
CCHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHHHH
NDVASLEAVSA
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]