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The map label for this gene is rraA

Identifier: 126209361

GI number: 126209361

Start: 2131532

End: 2132029

Strand: Reverse

Name: rraA

Synonym: APL_1901

Alternate gene names: 126209361

Gene position: 2132029-2131532 (Counterclockwise)

Preceding gene: 126209364

Following gene: 126209359

Centisome position: 93.74

GC content: 46.79

Gene sequence:

>498_bases
ATGCGTATTGATACCTCAGCACTTTGTGATATTTATTCCGATCAGGTCGATGTAGTCGAGCCAATCTTTTCGAGCTTTGG
CGGAGCCTCTTCTTTTTACGGTAAAATTACCACGGTAAAATGCTTTGAAAGCAACGGTTTAATTGCCAGCGTGTTAGAAG
AAGAAGGTCAAGGAAGAGTATTGCTGATTGACGGCGGCGGTGCGGTTCGTCGTGCATTAATCGATGCGGAACTGGCGCAA
CTTGCGCTTGATAACGGTTGGGAAGGAATTATCGTTTATGGTGCGGTTCGTCAGTTGGACGTATTGGAAACTTTGGACAT
CGGTATTCACGCATTAGCGCCGATTCCGGTCGGTGCCGATGATAACGAAATCGGCGAAGTCGATACGCCGGTGAATTTCG
GCGGCGTGACTTTCTTCCCGGAAGATTATGTTTATGCGGATTTAACCGGCATTATTCTTTCGCCGGAATTGCTGGATTTA
GCAGAATTGGAAGAGTAA

Upstream 100 bases:

>100_bases
GTTTCGCAAAATAAGCGGTCATTTTCGGCAAAAATTTTGCAAATGGCATAGTTAGGTTTATACTTTGAAATAATGACATC
TTTTACAAAAGGAATAGCTT

Downstream 100 bases:

>100_bases
CCCATCGAATATAGAAAACCGACCGCTTGGTCGGTTTTTTGTTTGGCTACATATTTAAATAAAACGCCTTGGTTAGCTGC
TTGAACGCTTCGGTATATTG

Product: ribonuclease activity regulator protein RraA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 165; Mature: 165

Protein sequence:

>165_residues
MRIDTSALCDIYSDQVDVVEPIFSSFGGASSFYGKITTVKCFESNGLIASVLEEEGQGRVLLIDGGGAVRRALIDAELAQ
LALDNGWEGIIVYGAVRQLDVLETLDIGIHALAPIPVGADDNEIGEVDTPVNFGGVTFFPEDYVYADLTGIILSPELLDL
AELEE

Sequences:

>Translated_165_residues
MRIDTSALCDIYSDQVDVVEPIFSSFGGASSFYGKITTVKCFESNGLIASVLEEEGQGRVLLIDGGGAVRRALIDAELAQ
LALDNGWEGIIVYGAVRQLDVLETLDIGIHALAPIPVGADDNEIGEVDTPVNFGGVTFFPEDYVYADLTGIILSPELLDL
AELEE
>Mature_165_residues
MRIDTSALCDIYSDQVDVVEPIFSSFGGASSFYGKITTVKCFESNGLIASVLEEEGQGRVLLIDGGGAVRRALIDAELAQ
LALDNGWEGIIVYGAVRQLDVLETLDIGIHALAPIPVGADDNEIGEVDTPVNFGGVTFFPEDYVYADLTGIILSPELLDL
AELEE

Specific function: Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities

COG id: COG0684

COG function: function code H; Demethylmenaquinone methyltransferase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RraA family

Homologues:

Organism=Escherichia coli, GI1790364, Length=160, Percent_Identity=65.625, Blast_Score=215, Evalue=1e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RRAA_ACTP2 (A3N3J5)

Other databases:

- EMBL:   CP000569
- RefSeq:   YP_001054586.1
- ProteinModelPortal:   A3N3J5
- SMR:   A3N3J5
- STRING:   A3N3J5
- GeneID:   4850450
- GenomeReviews:   CP000569_GR
- KEGG:   apl:APL_1901
- eggNOG:   COG0684
- HOGENOM:   HBG668175
- OMA:   QNEWEGI
- PhylomeDB:   A3N3J5
- ProtClustDB:   PRK09372
- BioCyc:   APLE416269:APL_1901-MONOMER
- HAMAP:   MF_00471
- InterPro:   IPR005493
- InterPro:   IPR014339
- InterPro:   IPR010203
- Gene3D:   G3DSA:3.50.30.40
- TIGRFAMs:   TIGR01935
- TIGRFAMs:   TIGR02998

Pfam domain/function: PF03737 Methyltransf_6; SSF89562 RNaseE_inh/diMeMenaQ_MeTrfase

EC number: NA

Molecular weight: Translated: 17625; Mature: 17625

Theoretical pI: Translated: 3.59; Mature: 3.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIDTSALCDIYSDQVDVVEPIFSSFGGASSFYGKITTVKCFESNGLIASVLEEEGQGRV
CCCCHHHHHHHHCCCHHHHHHHHHHCCCCCCCCEEEEEEEEECCCCEEEEEHHHCCCCEE
LLIDGGGAVRRALIDAELAQLALDNGWEGIIVYGAVRQLDVLETLDIGIHALAPIPVGAD
EEEECCHHHHHHHHHHHHHHHHHCCCCCEEEEEECHHHHHHHHHHHCCEEEECCCCCCCC
DNEIGEVDTPVNFGGVTFFPEDYVYADLTGIILSPELLDLAELEE
CCCCCCCCCCCCCCCEEECCCCCEEEEEEEEEECCCHHHHHHCCC
>Mature Secondary Structure
MRIDTSALCDIYSDQVDVVEPIFSSFGGASSFYGKITTVKCFESNGLIASVLEEEGQGRV
CCCCHHHHHHHHCCCHHHHHHHHHHCCCCCCCCEEEEEEEEECCCCEEEEEHHHCCCCEE
LLIDGGGAVRRALIDAELAQLALDNGWEGIIVYGAVRQLDVLETLDIGIHALAPIPVGAD
EEEECCHHHHHHHHHHHHHHHHHCCCCCEEEEEECHHHHHHHHHHHCCEEEECCCCCCCC
DNEIGEVDTPVNFGGVTFFPEDYVYADLTGIILSPELLDLAELEE
CCCCCCCCCCCCCCCEEECCCCCEEEEEEEEEECCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA