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The map label for this gene is ap2029 [H]

Identifier: 126209358

GI number: 126209358

Start: 2129311

End: 2130078

Strand: Reverse

Name: ap2029 [H]

Synonym: APL_1898

Alternate gene names: 126209358

Gene position: 2130078-2129311 (Counterclockwise)

Preceding gene: 126209359

Following gene: 126209357

Centisome position: 93.65

GC content: 46.88

Gene sequence:

>768_bases
ATGAAATTGATTAAAAAAATTGGCGCAGCCGCATTTTTAGTTTCAGCGATTGCGGCTTGCGTCAGTACTCAAAGTATTAA
CCAAGAAGCGGCGCAAAGCTATGCGCAAGTAAAAAGCCAAGCACAAGCGGAAAGAGCGGTAGATGCAAGTTCCGCAACCG
CACGCCGTATCCATACGGTATTTAATAAAATGAAGCCTTATGCGGAAAGAGCGAATACGACCGGCGTGCCGTTCCAATGG
GAAATTACCGTGTTAAAATCCGACGAAATGAACGCTTGGGCGATGCCGGGCGGTAAAATGGCGTTTTATACAGGATTGGT
CAATAAGTTAAACTTAAATGATGACGAAATTGCGACCGTGATGGGACACGAAATGGCACACGCTTTATTGGAACACGGGA
AATCGGATCGTACCTTTAATGCGGTAACCGGCATTGTGGCGCAAGTCGGCTCAATCGCTTTACAATCGCAAGGGATTCAA
ACCAATTTCGGCGGTGTGGATTTGGTCGGCACGGTGGCGGATCTCGGTTTAAACAAGCCGTTTTCTCGTAGCCAAGAAAC
CGAAGCGGACGAAATCGGCTTAATCTTAATGGCGCAATCCGGCTACAATCCTTCGGCGGCACCGAACGTATGGGTCAAAA
TGAGTAAAGTAGGCGGCAGCTCGGGCAGTTCTATTTTCTCTACTCACCCGTCAAACGAAGATCGTCAGGAAAATTTACAA
CGCTTACTACCTGAAGCGATGAAAGTGTATCAAACCAGTAAAAAATAG

Upstream 100 bases:

>100_bases
AATAATTGTTGTTTTTAGAACGAGATGCCAAACACTCACAGAGTGCTTGGCATTTTTTCTATGGCAAATAAATAACCCAT
TTATTTTCTAGGGGAATAAA

Downstream 100 bases:

>100_bases
TTTAAAACAAGCAGTTTAATTTATTCCGTTTTTTGCAATAGGCAGATCGTTTGGATCTGTCTTATTTTTTTGTTTAAAAA
ACAACCGGTTTAAAACAGTC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 255; Mature: 255

Protein sequence:

>255_residues
MKLIKKIGAAAFLVSAIAACVSTQSINQEAAQSYAQVKSQAQAERAVDASSATARRIHTVFNKMKPYAERANTTGVPFQW
EITVLKSDEMNAWAMPGGKMAFYTGLVNKLNLNDDEIATVMGHEMAHALLEHGKSDRTFNAVTGIVAQVGSIALQSQGIQ
TNFGGVDLVGTVADLGLNKPFSRSQETEADEIGLILMAQSGYNPSAAPNVWVKMSKVGGSSGSSIFSTHPSNEDRQENLQ
RLLPEAMKVYQTSKK

Sequences:

>Translated_255_residues
MKLIKKIGAAAFLVSAIAACVSTQSINQEAAQSYAQVKSQAQAERAVDASSATARRIHTVFNKMKPYAERANTTGVPFQW
EITVLKSDEMNAWAMPGGKMAFYTGLVNKLNLNDDEIATVMGHEMAHALLEHGKSDRTFNAVTGIVAQVGSIALQSQGIQ
TNFGGVDLVGTVADLGLNKPFSRSQETEADEIGLILMAQSGYNPSAAPNVWVKMSKVGGSSGSSIFSTHPSNEDRQENLQ
RLLPEAMKVYQTSKK
>Mature_255_residues
MKLIKKIGAAAFLVSAIAACVSTQSINQEAAQSYAQVKSQAQAERAVDASSATARRIHTVFNKMKPYAERANTTGVPFQW
EITVLKSDEMNAWAMPGGKMAFYTGLVNKLNLNDDEIATVMGHEMAHALLEHGKSDRTFNAVTGIVAQVGSIALQSQGIQ
TNFGGVDLVGTVADLGLNKPFSRSQETEADEIGLILMAQSGYNPSAAPNVWVKMSKVGGSSGSSIFSTHPSNEDRQENLQ
RLLPEAMKVYQTSKK

Specific function: Seems to regulate the expression of speB [H]

COG id: COG0501

COG function: function code O; Zn-dependent protease with chaperone function

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M48B family [H]

Homologues:

Organism=Homo sapiens, GI21686999, Length=185, Percent_Identity=31.3513513513514, Blast_Score=96, Evalue=4e-20,
Organism=Escherichia coli, GI87082185, Length=240, Percent_Identity=30, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI87081800, Length=259, Percent_Identity=26.2548262548263, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1788840, Length=173, Percent_Identity=31.2138728323699, Blast_Score=72, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6322940, Length=235, Percent_Identity=28.5106382978723, Blast_Score=97, Evalue=2e-21,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001915 [H]

Pfam domain/function: PF01435 Peptidase_M48 [H]

EC number: 3.4.24.- [C]

Molecular weight: Translated: 27395; Mature: 27395

Theoretical pI: Translated: 8.45; Mature: 8.45

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLIKKIGAAAFLVSAIAACVSTQSINQEAAQSYAQVKSQAQAERAVDASSATARRIHTV
CHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
FNKMKPYAERANTTGVPFQWEITVLKSDEMNAWAMPGGKMAFYTGLVNKLNLNDDEIATV
HHHHHHHHHHCCCCCCCEEEEEEEEECCCCCEEECCCCCHHHHHHHHHHCCCCHHHHHHH
MGHEMAHALLEHGKSDRTFNAVTGIVAQVGSIALQSQGIQTNFGGVDLVGTVADLGLNKP
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCC
FSRSQETEADEIGLILMAQSGYNPSAAPNVWVKMSKVGGSSGSSIFSTHPSNEDRQENLQ
CCCCCCCCCCCCCEEEEECCCCCCCCCCCEEEEEEECCCCCCCCEEECCCCCCHHHHHHH
RLLPEAMKVYQTSKK
HHHHHHHHHHHHCCC
>Mature Secondary Structure
MKLIKKIGAAAFLVSAIAACVSTQSINQEAAQSYAQVKSQAQAERAVDASSATARRIHTV
CHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
FNKMKPYAERANTTGVPFQWEITVLKSDEMNAWAMPGGKMAFYTGLVNKLNLNDDEIATV
HHHHHHHHHHCCCCCCCEEEEEEEEECCCCCEEECCCCCHHHHHHHHHHCCCCHHHHHHH
MGHEMAHALLEHGKSDRTFNAVTGIVAQVGSIALQSQGIQTNFGGVDLVGTVADLGLNKP
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCC
FSRSQETEADEIGLILMAQSGYNPSAAPNVWVKMSKVGGSSGSSIFSTHPSNEDRQENLQ
CCCCCCCCCCCCCEEEEECCCCCCCCCCCEEEEEEECCCCCCCCEEECCCCCCHHHHHHH
RLLPEAMKVYQTSKK
HHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2153656; 9278503; 1310091 [H]