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The map label for this gene is udp [H]

Identifier: 126209301

GI number: 126209301

Start: 2062838

End: 2063602

Strand: Direct

Name: udp [H]

Synonym: APL_1839

Alternate gene names: 126209301

Gene position: 2062838-2063602 (Clockwise)

Preceding gene: 126209300

Following gene: 126209302

Centisome position: 90.69

GC content: 47.06

Gene sequence:

>765_bases
ATGTCCGAAGTATTCCATTTAGGTTTAACTAAAGCCATGTTAAAAGGGGCAAAAGTAGCAATTGTTCCCGGTGATCCGGC
TCGTAGTGAGCGTATTGCCCAAAAAATGCAGAATCCTGAATTTCTCGTTTCAACCCGTGAATTTACCTCTTGGTTAGGTT
ATGTCGGCGGAGAGCCGATTGTCGTTTGTTCAACCGGTATCGGCGGTCCGTCAGTATCAATTTGTGTGGAAGAATTGGCT
CAACTCGGTGTACGTACGTTCTTACGTATCGGTACGACCGGTGCGATCCAACCGCATATTAATGTGGGTGAGGTACTGGT
TACGACCGGTGCGGTTCGCTTAGACGGCGCAAGTCGTCACTTTGCACCGTTAGAATATCCGGCGGTAGCAAACTTCGAAT
GTACCAATGAGCTTTATGCCGCAGCGAAAAATCAGGGGGTAACGCCTTATGTCGGTATTACCGCCTCATCCGATACTTTC
TATCCGGGGCAAGAACGTTACGATACGTATAGCGGTAAAGTCTATCGCCATTTCCAAGGTTCGCTAAAACAATGGCAAGA
GCTTAACGTAATGAACTTTGAAATGGAGTCTGCGACATTGTTTACTATGTGTTCCGCACTTGGTTTACGTGCCGGTATGG
TTTCAGGCGTAATTGTAAATCGTACGCAACAAGAGATTCCGAATGAAGCGACAATTCACGCAATCGAACAAACAGCAATT
GCGGTGGCGGTTGAAGCGGCGGGAAAACTGGCTAAATCGGCTTAA

Upstream 100 bases:

>100_bases
TTGCAAATTTTTTATTAAAAACAATCGCTTATCTTGAGCTTTCGTGATTGAATAGCGTTAAGTTTTATATTTTATTAGTG
TCCAAATAAAGGAGATACGT

Downstream 100 bases:

>100_bases
TGGATTAAAGTTCACAACAAGCGGTCGGATTGTTAAAATACTTTGCAATCTCACCGCTTTTTTATGTTTATGTTACGACA
ATATCGCCGAATCTTAGCGC

Product: uridine phosphorylase

Products: NA

Alternate protein names: UPase; UrdPase [H]

Number of amino acids: Translated: 254; Mature: 253

Protein sequence:

>254_residues
MSEVFHLGLTKAMLKGAKVAIVPGDPARSERIAQKMQNPEFLVSTREFTSWLGYVGGEPIVVCSTGIGGPSVSICVEELA
QLGVRTFLRIGTTGAIQPHINVGEVLVTTGAVRLDGASRHFAPLEYPAVANFECTNELYAAAKNQGVTPYVGITASSDTF
YPGQERYDTYSGKVYRHFQGSLKQWQELNVMNFEMESATLFTMCSALGLRAGMVSGVIVNRTQQEIPNEATIHAIEQTAI
AVAVEAAGKLAKSA

Sequences:

>Translated_254_residues
MSEVFHLGLTKAMLKGAKVAIVPGDPARSERIAQKMQNPEFLVSTREFTSWLGYVGGEPIVVCSTGIGGPSVSICVEELA
QLGVRTFLRIGTTGAIQPHINVGEVLVTTGAVRLDGASRHFAPLEYPAVANFECTNELYAAAKNQGVTPYVGITASSDTF
YPGQERYDTYSGKVYRHFQGSLKQWQELNVMNFEMESATLFTMCSALGLRAGMVSGVIVNRTQQEIPNEATIHAIEQTAI
AVAVEAAGKLAKSA
>Mature_253_residues
SEVFHLGLTKAMLKGAKVAIVPGDPARSERIAQKMQNPEFLVSTREFTSWLGYVGGEPIVVCSTGIGGPSVSICVEELAQ
LGVRTFLRIGTTGAIQPHINVGEVLVTTGAVRLDGASRHFAPLEYPAVANFECTNELYAAAKNQGVTPYVGITASSDTFY
PGQERYDTYSGKVYRHFQGSLKQWQELNVMNFEMESATLFTMCSALGLRAGMVSGVIVNRTQQEIPNEATIHAIEQTAIA
VAVEAAGKLAKSA

Specific function: Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synth

COG id: COG2820

COG function: function code F; Uridine phosphorylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP/UDP phosphorylase family [H]

Homologues:

Organism=Escherichia coli, GI1790265, Length=249, Percent_Identity=70.281124497992, Blast_Score=374, Evalue=1e-105,
Organism=Escherichia coli, GI1790844, Length=204, Percent_Identity=30.3921568627451, Blast_Score=91, Evalue=8e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018017
- InterPro:   IPR018016
- InterPro:   IPR000845
- InterPro:   IPR010058 [H]

Pfam domain/function: PF01048 PNP_UDP_1 [H]

EC number: =2.4.2.3 [H]

Molecular weight: Translated: 27276; Mature: 27145

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: PS01232 PNP_UDP_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEVFHLGLTKAMLKGAKVAIVPGDPARSERIAQKMQNPEFLVSTREFTSWLGYVGGEPI
CCCHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHCCCCEEEEHHHHHHHHHHCCCCEE
VVCSTGIGGPSVSICVEELAQLGVRTFLRIGTTGAIQPHINVGEVLVTTGAVRLDGASRH
EEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCEEEECCCCCC
FAPLEYPAVANFECTNELYAAAKNQGVTPYVGITASSDTFYPGQERYDTYSGKVYRHFQG
CCCCCCCCCCCCCHHHHHHHHHCCCCCCCEEEEEECCCCCCCCHHHCCCCCCEEHHHHHH
SLKQWQELNVMNFEMESATLFTMCSALGLRAGMVSGVIVNRTQQEIPNEATIHAIEQTAI
HHHHHHHCCEEEEECCHHHHHHHHHHHHHHHHHHHHHEEECHHHHCCCHHHHHHHHHHHH
AVAVEAAGKLAKSA
HHHHHHHHHHHCCC
>Mature Secondary Structure 
SEVFHLGLTKAMLKGAKVAIVPGDPARSERIAQKMQNPEFLVSTREFTSWLGYVGGEPI
CCHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHCCCCEEEEHHHHHHHHHHCCCCEE
VVCSTGIGGPSVSICVEELAQLGVRTFLRIGTTGAIQPHINVGEVLVTTGAVRLDGASRH
EEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCEEEECCCCCC
FAPLEYPAVANFECTNELYAAAKNQGVTPYVGITASSDTFYPGQERYDTYSGKVYRHFQG
CCCCCCCCCCCCCHHHHHHHHHCCCCCCCEEEEEECCCCCCCCHHHCCCCCCEEHHHHHH
SLKQWQELNVMNFEMESATLFTMCSALGLRAGMVSGVIVNRTQQEIPNEATIHAIEQTAI
HHHHHHHCCEEEEECCHHHHHHHHHHHHHHHHHHHHHEEECHHHHCCCHHHHHHHHHHHH
AVAVEAAGKLAKSA
HHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]