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The map label for this gene is recG [H]

Identifier: 126209289

GI number: 126209289

Start: 2049552

End: 2051633

Strand: Reverse

Name: recG [H]

Synonym: APL_1827

Alternate gene names: 126209289

Gene position: 2051633-2049552 (Counterclockwise)

Preceding gene: 126209290

Following gene: 126209288

Centisome position: 90.2

GC content: 48.17

Gene sequence:

>2082_bases
ATGAGCGAACAATTACTAGACGGTGTGCCACTTACCGCCCTTTCCGGGGTGGGTGCGGCGATTGCGGAAAAACTTAGCCG
AATCGGCATTAATAACGTACAAGATCTATTATTTCATTTGCCTTATCGCTATGAAGATCGCACCCGAATTACGCCGATTA
TCGATGTGCGTCCGGAAAGTTTTTCTACCATCGAAGGTATCGTGCAAGTTACCGAAGTACAATTCGGTCGCCGTCCGATT
TTATCCACCGTGCTTTCTGACGGCACCAGTAAAATTACGCTGAAATTCTTTAATTTTAATGCGGGGATGAAAAACAGCCT
GACTGCCGGCACACGTGTAAAAGCTTTTGGCGAAATCAAACGCGGACGTTTTATGGCGGAAATTCATCACCCCGAATATC
AAATTATTCGCAATAATCAACCGCTTGAACTTGCCGAAACTTTAACGCCGATTTACTCCGCTACGGAAGGCCTGAAGCAA
AATTCGTTACGTAAACTCACCGAGCAAGCGTTAGCGTTATTGGATAAAATCAAAGTCGGTGAGCTGTTGCCAGACGAATA
CAATCCGCATAAATACAGCTTAAAAGGGGCATTGCAATTATTACACCGCCCGCCACCGAGCGTTTCTGCCGAACAGTTGG
AAAAAGGTGAGCATCCGGCACAAAAACGGCTGATTTTTGAAGAATTACTGGCGCACAACTTAGCAATGCAGCAAGTGCGA
GTCGGAGTCAATCAGCTGACTGCTACGCCGCTACGCTATCAAACCGATCTCAAAAGCCGCTTTTTGGCGAGTTTGCCGTT
TAAACCGACCAACGCTCAAAGCCGCGTGACGGCGGATATTGAGCAGGACTTAGCCAAATCCTCACCAATGATGCGATTAG
TACAAGGCGATGTCGGCTCGGGCAAAACCTTAGTCGCTGCGCTTGCCGCCCTGCTGGCGATTGATAACGGCAAACAAGTG
GCATTAATGGCACCGACCGAAATCCTTGCCGAGCAGCACGCCAATAACTTTGCCAACTGGCTACGCCCGTTCGGTATTGA
AGTCGGCTGGCTTGCCGGTAAAGTCAAAGGCAAAGCTCGCACCGCACAACTGGAAGCGATTAAAAACGGCGAAGTGCAGA
TGATTATCGGCACGCACGCCCTCTTCCAAGAAAGCGTCGAGTTTCATAACCTCGCATTAGTGATTATTGATGAACAACAC
CGTTTTGGTGTACATCAACGCTTAACCCTACGTGAAAAAGGGGCGAAAGACGGTATTTATCCGCACCAGCTAATTATGAC
TGCTACGCCAATTCCTCGTACCTTAGCAATGACGGTCTATGCCGATCTGGATACCTCTATTATTGACGAGCTACCACCGG
GGCGAACGCCGATTACTACCGTGGCGATTTCGGAAGACAGACGAGATGAAATTGTGCGTCGTGTGTATGCCGCCTGCAAA
AACGAAAAACGCCAAGCCTATTGGGTTTGTACCCTAATTGATGAATCGGAAGTCTTGGAAGCACAAGCTGCGGCGGCGAT
TGCCGAAGATTTACAACGAGCCTTACCGGATTTACGCATCGGCTTGGTACACGGACGAATGAAGCCGCAAGAAAAGCAAG
AAATTATGGCGGAATTTAAAGCGGCGAATATCGATTTATTGGTTGCCACCACAGTGATTGAAGTGGGGGTTGATGTGCCG
AATGCAAGCCTAATGATTATCGAAAACTCCGAACGTTTAGGGCTTGCTCAACTCCATCAATTACGTGGACGTGTCGGACG
TGGTGCAACCGCTTCCCATTGCGTGTTGCTGTATAAACCGCCGCTCGGCAAAATCTCGAGTAAACGCTTACAAGTGTTAC
GTGACAGCCAAGACGGTTTCTATATTGCCGAAAAAGATTTAGAAATTCGCGGCACGGGTGAAATTCTCGGTACCAAACAA
ACCGGTATGGCGGAATTTAAAGTGGCGAATTTAATGCGAGATCGCAAAATGATTCCATTAGTACAAAACTATGCCAAGCA
AATTATTCAGCAAAATCCACCGCTTGCCGAAGCACTGATTCGCCGCTGGCTGGGCGAGCGTACCGAATACAGCAACGCCT
AA

Upstream 100 bases:

>100_bases
TTTTTTAAAGAAATCCGACCGCTTGATTTGTACATAAAAACAGTATTTGTTATATTAACCCAATCGAAAACAAGCGGTCG
GATTTAATCAAAATTTTACT

Downstream 100 bases:

>100_bases
TCGCAAGCGGTCTGATTTGCTGAATTTTTTGCAAATTAAACCGCTTGCATTGTAAGCAGATACGAATTTCTGTATAATCT
CTCGTCTTTTTATAAACGAA

Product: ATP-dependent DNA helicase RecG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 693; Mature: 692

Protein sequence:

>693_residues
MSEQLLDGVPLTALSGVGAAIAEKLSRIGINNVQDLLFHLPYRYEDRTRITPIIDVRPESFSTIEGIVQVTEVQFGRRPI
LSTVLSDGTSKITLKFFNFNAGMKNSLTAGTRVKAFGEIKRGRFMAEIHHPEYQIIRNNQPLELAETLTPIYSATEGLKQ
NSLRKLTEQALALLDKIKVGELLPDEYNPHKYSLKGALQLLHRPPPSVSAEQLEKGEHPAQKRLIFEELLAHNLAMQQVR
VGVNQLTATPLRYQTDLKSRFLASLPFKPTNAQSRVTADIEQDLAKSSPMMRLVQGDVGSGKTLVAALAALLAIDNGKQV
ALMAPTEILAEQHANNFANWLRPFGIEVGWLAGKVKGKARTAQLEAIKNGEVQMIIGTHALFQESVEFHNLALVIIDEQH
RFGVHQRLTLREKGAKDGIYPHQLIMTATPIPRTLAMTVYADLDTSIIDELPPGRTPITTVAISEDRRDEIVRRVYAACK
NEKRQAYWVCTLIDESEVLEAQAAAAIAEDLQRALPDLRIGLVHGRMKPQEKQEIMAEFKAANIDLLVATTVIEVGVDVP
NASLMIIENSERLGLAQLHQLRGRVGRGATASHCVLLYKPPLGKISSKRLQVLRDSQDGFYIAEKDLEIRGTGEILGTKQ
TGMAEFKVANLMRDRKMIPLVQNYAKQIIQQNPPLAEALIRRWLGERTEYSNA

Sequences:

>Translated_693_residues
MSEQLLDGVPLTALSGVGAAIAEKLSRIGINNVQDLLFHLPYRYEDRTRITPIIDVRPESFSTIEGIVQVTEVQFGRRPI
LSTVLSDGTSKITLKFFNFNAGMKNSLTAGTRVKAFGEIKRGRFMAEIHHPEYQIIRNNQPLELAETLTPIYSATEGLKQ
NSLRKLTEQALALLDKIKVGELLPDEYNPHKYSLKGALQLLHRPPPSVSAEQLEKGEHPAQKRLIFEELLAHNLAMQQVR
VGVNQLTATPLRYQTDLKSRFLASLPFKPTNAQSRVTADIEQDLAKSSPMMRLVQGDVGSGKTLVAALAALLAIDNGKQV
ALMAPTEILAEQHANNFANWLRPFGIEVGWLAGKVKGKARTAQLEAIKNGEVQMIIGTHALFQESVEFHNLALVIIDEQH
RFGVHQRLTLREKGAKDGIYPHQLIMTATPIPRTLAMTVYADLDTSIIDELPPGRTPITTVAISEDRRDEIVRRVYAACK
NEKRQAYWVCTLIDESEVLEAQAAAAIAEDLQRALPDLRIGLVHGRMKPQEKQEIMAEFKAANIDLLVATTVIEVGVDVP
NASLMIIENSERLGLAQLHQLRGRVGRGATASHCVLLYKPPLGKISSKRLQVLRDSQDGFYIAEKDLEIRGTGEILGTKQ
TGMAEFKVANLMRDRKMIPLVQNYAKQIIQQNPPLAEALIRRWLGERTEYSNA
>Mature_692_residues
SEQLLDGVPLTALSGVGAAIAEKLSRIGINNVQDLLFHLPYRYEDRTRITPIIDVRPESFSTIEGIVQVTEVQFGRRPIL
STVLSDGTSKITLKFFNFNAGMKNSLTAGTRVKAFGEIKRGRFMAEIHHPEYQIIRNNQPLELAETLTPIYSATEGLKQN
SLRKLTEQALALLDKIKVGELLPDEYNPHKYSLKGALQLLHRPPPSVSAEQLEKGEHPAQKRLIFEELLAHNLAMQQVRV
GVNQLTATPLRYQTDLKSRFLASLPFKPTNAQSRVTADIEQDLAKSSPMMRLVQGDVGSGKTLVAALAALLAIDNGKQVA
LMAPTEILAEQHANNFANWLRPFGIEVGWLAGKVKGKARTAQLEAIKNGEVQMIIGTHALFQESVEFHNLALVIIDEQHR
FGVHQRLTLREKGAKDGIYPHQLIMTATPIPRTLAMTVYADLDTSIIDELPPGRTPITTVAISEDRRDEIVRRVYAACKN
EKRQAYWVCTLIDESEVLEAQAAAAIAEDLQRALPDLRIGLVHGRMKPQEKQEIMAEFKAANIDLLVATTVIEVGVDVPN
ASLMIIENSERLGLAQLHQLRGRVGRGATASHCVLLYKPPLGKISSKRLQVLRDSQDGFYIAEKDLEIRGTGEILGTKQT
GMAEFKVANLMRDRKMIPLVQNYAKQIIQQNPPLAEALIRRWLGERTEYSNA

Specific function: Critical role in recombination and DNA repair. Help process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3' to 5' polarity. RecG unwind branched dup

COG id: COG1200

COG function: function code LK; RecG-like helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI2367254, Length=693, Percent_Identity=65.9451659451659, Blast_Score=912, Evalue=0.0,
Organism=Escherichia coli, GI1787357, Length=397, Percent_Identity=39.5465994962217, Blast_Score=250, Evalue=2e-67,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004609
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C; PF01336 tRNA_anti [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 77055; Mature: 76924

Theoretical pI: Translated: 9.06; Mature: 9.06

Prosite motif: PS00435 PEROXIDASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEQLLDGVPLTALSGVGAAIAEKLSRIGINNVQDLLFHLPYRYEDRTRITPIIDVRPES
CCCCHHCCCCHHHHHCCHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCEEEEECCCC
FSTIEGIVQVTEVQFGRRPILSTVLSDGTSKITLKFFNFNAGMKNSLTAGTRVKAFGEIK
HHHHHHHHHHHHHHCCCHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCCCHHHHHHHHH
RGRFMAEIHHPEYQIIRNNQPLELAETLTPIYSATEGLKQNSLRKLTEQALALLDKIKVG
CCCEEEEECCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
ELLPDEYNPHKYSLKGALQLLHRPPPSVSAEQLEKGEHPAQKRLIFEELLAHNLAMQQVR
CCCCCCCCCCEEHHHHHHHHHHCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
VGVNQLTATPLRYQTDLKSRFLASLPFKPTNAQSRVTADIEQDLAKSSPMMRLVQGDVGS
HHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCHHEEHHHHHHHHHCCCHHHHHCCCCCC
GKTLVAALAALLAIDNGKQVALMAPTEILAEQHANNFANWLRPFGIEVGWLAGKVKGKAR
CHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCH
TAQLEAIKNGEVQMIIGTHALFQESVEFHNLALVIIDEQHRFGVHQRLTLREKGAKDGIY
HHHHHHCCCCCEEEEECCHHHHHHHHCCCCEEEEEEECCHHCCCHHEEHHHHCCCCCCCC
PHQLIMTATPIPRTLAMTVYADLDTSIIDELPPGRTPITTVAISEDRRDEIVRRVYAACK
CCEEEEECCCCCCEEEEEEEECCCHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHC
NEKRQAYWVCTLIDESEVLEAQAAAAIAEDLQRALPDLRIGLVHGRMKPQEKQEIMAEFK
CCCCEEEEEEEEECCHHHHHHHHHHHHHHHHHHHCCHHEEEEEECCCCCHHHHHHHHHHH
AANIDLLVATTVIEVGVDVPNASLMIIENSERLGLAQLHQLRGRVGRGATASHCVLLYKP
HCCEEEEHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHHCCCCCCCCCEEEEECC
PLGKISSKRLQVLRDSQDGFYIAEKDLEIRGTGEILGTKQTGMAEFKVANLMRDRKMIPL
CCCCCHHHHHHHHHCCCCCEEEEECCEEEEECCCEECCCCCCCHHHHHHHHHHCCCCCHH
VQNYAKQIIQQNPPLAEALIRRWLGERTEYSNA
HHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
SEQLLDGVPLTALSGVGAAIAEKLSRIGINNVQDLLFHLPYRYEDRTRITPIIDVRPES
CCCHHCCCCHHHHHCCHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCEEEEECCCC
FSTIEGIVQVTEVQFGRRPILSTVLSDGTSKITLKFFNFNAGMKNSLTAGTRVKAFGEIK
HHHHHHHHHHHHHHCCCHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCCCHHHHHHHHH
RGRFMAEIHHPEYQIIRNNQPLELAETLTPIYSATEGLKQNSLRKLTEQALALLDKIKVG
CCCEEEEECCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
ELLPDEYNPHKYSLKGALQLLHRPPPSVSAEQLEKGEHPAQKRLIFEELLAHNLAMQQVR
CCCCCCCCCCEEHHHHHHHHHHCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
VGVNQLTATPLRYQTDLKSRFLASLPFKPTNAQSRVTADIEQDLAKSSPMMRLVQGDVGS
HHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCHHEEHHHHHHHHHCCCHHHHHCCCCCC
GKTLVAALAALLAIDNGKQVALMAPTEILAEQHANNFANWLRPFGIEVGWLAGKVKGKAR
CHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCH
TAQLEAIKNGEVQMIIGTHALFQESVEFHNLALVIIDEQHRFGVHQRLTLREKGAKDGIY
HHHHHHCCCCCEEEEECCHHHHHHHHCCCCEEEEEEECCHHCCCHHEEHHHHCCCCCCCC
PHQLIMTATPIPRTLAMTVYADLDTSIIDELPPGRTPITTVAISEDRRDEIVRRVYAACK
CCEEEEECCCCCCEEEEEEEECCCHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHC
NEKRQAYWVCTLIDESEVLEAQAAAAIAEDLQRALPDLRIGLVHGRMKPQEKQEIMAEFK
CCCCEEEEEEEEECCHHHHHHHHHHHHHHHHHHHCCHHEEEEEECCCCCHHHHHHHHHHH
AANIDLLVATTVIEVGVDVPNASLMIIENSERLGLAQLHQLRGRVGRGATASHCVLLYKP
HCCEEEEHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHHCCCCCCCCCEEEEECC
PLGKISSKRLQVLRDSQDGFYIAEKDLEIRGTGEILGTKQTGMAEFKVANLMRDRKMIPL
CCCCCHHHHHHHHHCCCCCEEEEECCEEEEECCCEECCCCCCCHHHHHHHHHHCCCCCHH
VQNYAKQIIQQNPPLAEALIRRWLGERTEYSNA
HHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]