Click here to switch to the map view.

The map label for this gene is xerC [H]

Identifier: 126209269

GI number: 126209269

Start: 2028258

End: 2029268

Strand: Direct

Name: xerC [H]

Synonym: APL_1805

Alternate gene names: 126209269

Gene position: 2028258-2029268 (Clockwise)

Preceding gene: 126209268

Following gene: 126209275

Centisome position: 89.17

GC content: 44.02

Gene sequence:

>1011_bases
TTGAATCAAGCGGTTGTTTTTGCAAAAAATTTTGCAAATTTGACCGCTTGTTTTCCTTTCTCGTTTACTTCCTTTCAACG
TGTCATCGTTATGATTAATTCACAAAATACGCTCTATCTGCAAACTAAGCCCTATTGGGATTACTTACGTATCGAAAAAC
AAGCCAGCCAACATACATTGAGTAATTATCAGCGTCAGCTTTTAGCGGTGAGCGATATGCTTAGTCAAGCCGGTATTAGC
ACATGGCAAGAGGTGAATAGTGCGACGGTGCGTTGGATTATCGCGCAAAGTAATAAGCAGGGCTTAGGGGCAAAGAGTAT
CGCTTTACGTTTGGTTGCGTTACGTCAATGGTTTAGTTATTTGATTCGACAAGAAAAGATGTCGGTTAATCCGGCGGTTG
GCATTAAAGCACCGAAAGCAAGCAAGCGTTTACCGAAGAATATTGATGCGGAACAAATCGGGCAACTATTAACCAGCGAT
AGCCATGAACCGAGCGACTTGCGTGATCTGGCGATGATGGAATTGATGTACAGCTCCGGCTTGCGTCTATCCGAGTTGCA
AGGGCTTGATTTGGGCGATATGGATTTAGCCGGACGAGAAGTGCGTTTATTGGGTAAAGGGAATAAAGAACGTATCGTGC
CGATTGGTTCGAAAGCCCTTGAAGCGTTAAATCGTTGGTTGGCGGTAAGAAATCAATTTAAACCGCAGGACAATGCGGTA
TTTTTGAATAAGCGCGGCGGTAGATTGTCACACCGTTCAATTCAACTTGTCATGCAAAAATGGGGCGAGAAACAGGGCTT
GGAAAGCCATTTGCATCCGCATAAATTGCGCCATTCGTTTGCCACTCATATGTTGGAAGCCAGCGGCGATTTACGTGCGG
TACAAGAATTACTCGGACATAGCAATCTTGCCACTACCCAAATTTATACACATTTGGATTTCCAACATCTTGCCAAAATT
TATGATGCGGCTCACCCGAGAGCTAAACGCAAAAAGCAAGACGACGATTAA

Upstream 100 bases:

>100_bases
CACCGATGTAAACGAACTTTTTGAATTTTTAGGCGATTATCTAAGTCCGGTGGCGTTAGGTAATGTCGGCGTACGTATCG
GTCAGCTTAATTTGGCGTAA

Downstream 100 bases:

>100_bases
AGGCTAAGCATTTGAACGGCTATCGCTTGTTTCCGGCGGAATAGTAGTGATTTTGCAGAAAAAGTACCAATATTGGCAAA
TAATCACGGCAATTAAAGTT

Product: site-specific tyrosine recombinase XerC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 336; Mature: 336

Protein sequence:

>336_residues
MNQAVVFAKNFANLTACFPFSFTSFQRVIVMINSQNTLYLQTKPYWDYLRIEKQASQHTLSNYQRQLLAVSDMLSQAGIS
TWQEVNSATVRWIIAQSNKQGLGAKSIALRLVALRQWFSYLIRQEKMSVNPAVGIKAPKASKRLPKNIDAEQIGQLLTSD
SHEPSDLRDLAMMELMYSSGLRLSELQGLDLGDMDLAGREVRLLGKGNKERIVPIGSKALEALNRWLAVRNQFKPQDNAV
FLNKRGGRLSHRSIQLVMQKWGEKQGLESHLHPHKLRHSFATHMLEASGDLRAVQELLGHSNLATTQIYTHLDFQHLAKI
YDAAHPRAKRKKQDDD

Sequences:

>Translated_336_residues
MNQAVVFAKNFANLTACFPFSFTSFQRVIVMINSQNTLYLQTKPYWDYLRIEKQASQHTLSNYQRQLLAVSDMLSQAGIS
TWQEVNSATVRWIIAQSNKQGLGAKSIALRLVALRQWFSYLIRQEKMSVNPAVGIKAPKASKRLPKNIDAEQIGQLLTSD
SHEPSDLRDLAMMELMYSSGLRLSELQGLDLGDMDLAGREVRLLGKGNKERIVPIGSKALEALNRWLAVRNQFKPQDNAV
FLNKRGGRLSHRSIQLVMQKWGEKQGLESHLHPHKLRHSFATHMLEASGDLRAVQELLGHSNLATTQIYTHLDFQHLAKI
YDAAHPRAKRKKQDDD
>Mature_336_residues
MNQAVVFAKNFANLTACFPFSFTSFQRVIVMINSQNTLYLQTKPYWDYLRIEKQASQHTLSNYQRQLLAVSDMLSQAGIS
TWQEVNSATVRWIIAQSNKQGLGAKSIALRLVALRQWFSYLIRQEKMSVNPAVGIKAPKASKRLPKNIDAEQIGQLLTSD
SHEPSDLRDLAMMELMYSSGLRLSELQGLDLGDMDLAGREVRLLGKGNKERIVPIGSKALEALNRWLAVRNQFKPQDNAV
FLNKRGGRLSHRSIQLVMQKWGEKQGLESHLHPHKLRHSFATHMLEASGDLRAVQELLGHSNLATTQIYTHLDFQHLAKI
YDAAHPRAKRKKQDDD

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4973

COG function: function code L; Site-specific recombinase XerC

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790244, Length=295, Percent_Identity=54.9152542372881, Blast_Score=335, Evalue=3e-93,
Organism=Escherichia coli, GI1789261, Length=292, Percent_Identity=36.6438356164384, Blast_Score=178, Evalue=4e-46,
Organism=Escherichia coli, GI1790768, Length=186, Percent_Identity=30.1075268817204, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1790767, Length=194, Percent_Identity=28.8659793814433, Blast_Score=83, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011931 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 38140; Mature: 38140

Theoretical pI: Translated: 10.42; Mature: 10.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQAVVFAKNFANLTACFPFSFTSFQRVIVMINSQNTLYLQTKPYWDYLRIEKQASQHTL
CCCEEEEEECCCCEEEECCCCHHHHEEEEEEEECCCEEEEEECCCHHHHHHHHHHHHHHH
SNYQRQLLAVSDMLSQAGISTWQEVNSATVRWIIAQSNKQGLGAKSIALRLVALRQWFSY
HHHHHHHHHHHHHHHHHCCHHHHHHCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHH
LIRQEKMSVNPAVGIKAPKASKRLPKNIDAEQIGQLLTSDSHEPSDLRDLAMMELMYSSG
HHHHHHCCCCCCCCCCCCCHHHCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCC
LRLSELQGLDLGDMDLAGREVRLLGKGNKERIVPIGSKALEALNRWLAVRNQFKPQDNAV
CCHHHHCCCCCCCCCCCCCEEEEEECCCCCEEEECCHHHHHHHHHHHHHHHCCCCCCCEE
FLNKRGGRLSHRSIQLVMQKWGEKQGLESHLHPHKLRHSFATHMLEASGDLRAVQELLGH
EEECCCCCCHHHHHHHHHHHHCCCCCHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCC
SNLATTQIYTHLDFQHLAKIYDAAHPRAKRKKQDDD
CCCCHHHHHHHCCHHHHHHHHHHCCCHHHCCCCCCC
>Mature Secondary Structure
MNQAVVFAKNFANLTACFPFSFTSFQRVIVMINSQNTLYLQTKPYWDYLRIEKQASQHTL
CCCEEEEEECCCCEEEECCCCHHHHEEEEEEEECCCEEEEEECCCHHHHHHHHHHHHHHH
SNYQRQLLAVSDMLSQAGISTWQEVNSATVRWIIAQSNKQGLGAKSIALRLVALRQWFSY
HHHHHHHHHHHHHHHHHCCHHHHHHCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHH
LIRQEKMSVNPAVGIKAPKASKRLPKNIDAEQIGQLLTSDSHEPSDLRDLAMMELMYSSG
HHHHHHCCCCCCCCCCCCCHHHCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCC
LRLSELQGLDLGDMDLAGREVRLLGKGNKERIVPIGSKALEALNRWLAVRNQFKPQDNAV
CCHHHHCCCCCCCCCCCCCEEEEEECCCCCEEEECCHHHHHHHHHHHHHHHCCCCCCCEE
FLNKRGGRLSHRSIQLVMQKWGEKQGLESHLHPHKLRHSFATHMLEASGDLRAVQELLGH
EEECCCCCCHHHHHHHHHHHHCCCCCHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCC
SNLATTQIYTHLDFQHLAKIYDAAHPRAKRKKQDDD
CCCCHHHHHHHCCHHHHHHHHHHCCCHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA