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The map label for this gene is neuA [H]

Identifier: 126209215

GI number: 126209215

Start: 1988860

End: 1989453

Strand: Direct

Name: neuA [H]

Synonym: APL_1751

Alternate gene names: 126209215

Gene position: 1988860-1989453 (Clockwise)

Preceding gene: 126209212

Following gene: 126209216

Centisome position: 87.44

GC content: 38.05

Gene sequence:

>594_bases
ATGTTATCAGATGCGGATGTTTTCCAACGTTATCAAACCAAGCGTATTGAGTTTGAAAGGGATACTGAAATTAGTTTAAT
CGGACATTCTCTGTTTGATATGTGGAGTGATTGGCAAACGAATCTCGAGTTTAAAGGACAAACGGTTGCTAATTTAGCTA
TTTCCGGTGTGAGTAGCCGCCAATATTTAGATGTTATAGCGAAACCGCAACATATTAAAAAGTTGGGACAATCCGTTTTC
TTTTTCCTCGGCGTGAACGATATTGTTAAAGAAGCCGATTATTCTCCGGCGCAAGTGATGGAATGGTTATTGCAAATTAT
TGAGCAAATTAGACCGCTTGCAACGCCAAATACTCGCTATTTTTTACTTGAAGCCACGCCTGTTTGTCGTATTAATACGG
TAACGAATGCTCAAATTCAGCAACTTAATACTTATTTAGCCGAACATTGTCCGCCCCATATTACATTTATTAAGACGTTT
GATGCGTTTGCTGATCATAAAGGCGATTTGAATGCCGATTTAACCACGGACGGGTTACATTTTAATTTACAAGGTTATGC
AGTTTTGCGTCAGTTATTAGAAAGCTATGTATAA

Upstream 100 bases:

>100_bases
AGAAGTACTTCACAGATTTTGAACTTTATGAATGAAAATTACTCCGTTAAAGCTATAATAAATGGCGTATTTATTAATAA
GTTTTGCGGAGTTTGGAGAA

Downstream 100 bases:

>100_bases
GCTTTATTTGAAAGCATAACGAACTCAAGGAGTTTATATGTCAAAGTTATCTCATTCGGAAGTATTGAATACGATTCGAA
ACGGTTTAATCGCTTCGTGT

Product: hypothetical protein

Products: NA

Alternate protein names: CMP-N-acetylneuraminic acid synthase; CMP-NeuNAc synthase [H]

Number of amino acids: Translated: 197; Mature: 197

Protein sequence:

>197_residues
MLSDADVFQRYQTKRIEFERDTEISLIGHSLFDMWSDWQTNLEFKGQTVANLAISGVSSRQYLDVIAKPQHIKKLGQSVF
FFLGVNDIVKEADYSPAQVMEWLLQIIEQIRPLATPNTRYFLLEATPVCRINTVTNAQIQQLNTYLAEHCPPHITFIKTF
DAFADHKGDLNADLTTDGLHFNLQGYAVLRQLLESYV

Sequences:

>Translated_197_residues
MLSDADVFQRYQTKRIEFERDTEISLIGHSLFDMWSDWQTNLEFKGQTVANLAISGVSSRQYLDVIAKPQHIKKLGQSVF
FFLGVNDIVKEADYSPAQVMEWLLQIIEQIRPLATPNTRYFLLEATPVCRINTVTNAQIQQLNTYLAEHCPPHITFIKTF
DAFADHKGDLNADLTTDGLHFNLQGYAVLRQLLESYV
>Mature_197_residues
MLSDADVFQRYQTKRIEFERDTEISLIGHSLFDMWSDWQTNLEFKGQTVANLAISGVSSRQYLDVIAKPQHIKKLGQSVF
FFLGVNDIVKEADYSPAQVMEWLLQIIEQIRPLATPNTRYFLLEATPVCRINTVTNAQIQQLNTYLAEHCPPHITFIKTF
DAFADHKGDLNADLTTDGLHFNLQGYAVLRQLLESYV

Specific function: Unknown

COG id: COG2755

COG function: function code E; Lysophospholipase L1 and related esterases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CMP-NeuNAc synthase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003329
- InterPro:   IPR013830
- InterPro:   IPR013831 [H]

Pfam domain/function: PF02348 CTP_transf_3 [H]

EC number: =2.7.7.43 [H]

Molecular weight: Translated: 22600; Mature: 22600

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSDADVFQRYQTKRIEFERDTEISLIGHSLFDMWSDWQTNLEFKGQTVANLAISGVSSR
CCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCEECCCHHHHHHHHCCCCH
QYLDVIAKPQHIKKLGQSVFFFLGVNDIVKEADYSPAQVMEWLLQIIEQIRPLATPNTRY
HHHHHHCCCHHHHHHHHHHEEEECHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCEE
FLLEATPVCRINTVTNAQIQQLNTYLAEHCPPHITFIKTFDAFADHKGDLNADLTTDGLH
EEEECCCEEEEECCCHHHHHHHHHHHHHHCCCCEEEHHHHHHHHCCCCCCCCCEECCCEE
FNLQGYAVLRQLLESYV
EECHHHHHHHHHHHHCC
>Mature Secondary Structure
MLSDADVFQRYQTKRIEFERDTEISLIGHSLFDMWSDWQTNLEFKGQTVANLAISGVSSR
CCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCEECCCHHHHHHHHCCCCH
QYLDVIAKPQHIKKLGQSVFFFLGVNDIVKEADYSPAQVMEWLLQIIEQIRPLATPNTRY
HHHHHHCCCHHHHHHHHHHEEEECHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCEE
FLLEATPVCRINTVTNAQIQQLNTYLAEHCPPHITFIKTFDAFADHKGDLNADLTTDGLH
EEEECCCEEEEECCCHHHHHHHHHHHHHHCCCCEEEHHHHHHHHCCCCCCCCCEECCCEE
FNLQGYAVLRQLLESYV
EECHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2549035 [H]