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The map label for this gene is fucR [H]

Identifier: 126209147

GI number: 126209147

Start: 1913060

End: 1913806

Strand: Direct

Name: fucR [H]

Synonym: APL_1683

Alternate gene names: 126209147

Gene position: 1913060-1913806 (Clockwise)

Preceding gene: 126209142

Following gene: 126209148

Centisome position: 84.11

GC content: 41.77

Gene sequence:

>747_bases
ATGGAAAGTCGTCATTCGTTAATTATTCGCTATTTGGAAGAATTTCATCAGGCAAGCGTTTTAGAACTTGCCGAACAGTT
TAATGTTTCGGTCGAAACGGTGCGTCGAGATTTAAATAAATTGGCGGCGGAAGGGCTGCTACATCGTACTCACGGCGGAG
CGGTAAGCAATAAACAACGGGATGTCGGCCGTTCGTTTCATGTTCGCCAGCGTATGAACAGTAATGCGAAAAAAATGATT
GCGGATAATGTGATTCATCATTTGTTTCCGGAAGCGACAATTGCGTTAGATGCCAGTTCGACTGCTTGGAATGTGGCACA
ACGAATTCCGAATATTCCGTGTAAAGTGGTCAGCAGCTCGATGCGGATTATTTACAGCTTATCGCATAAACCGCATATCG
AGACGATTGCGACCGGCGGCGTTTATGTCGAAAAATATAATGCGTTTTACGGTCCGTTGTCCGAACAATTGTTATCTCGC
TTAAAAATTGATATTGCGATTATTTCCTGTACCGGTGTTGCGGACGGTGCGATTTGGGAATCCAATGAGGTGAATATCGC
TTTTAAGCGAAAATTATTAGCGAATAGCAAACAAGTCTTTTTATTAGTCGATCACAGTAAACTTGAACGTAAAGATCGGT
TCAAAATGGCGGACTTATCCGAAGTGGATAAGTTATTTGTCAATCAACTTCCCCCTCAAACACTCCAAAATTATTGCGCA
CAAAATAGTATAGAAATTGTTCTCTAA

Upstream 100 bases:

>100_bases
TAATGTGATCGGACTCTAATATTTGGATTTCGTCGCTCGACAGCCAGTCGGCAAGCGGTTAGATTTAGTCGCATTTTTGT
AAACTGTTAGTTAAAAAATT

Downstream 100 bases:

>100_bases
TTGGTCTTTTTGCGAATAAATGCCCGATTTTTTGCCTGTTTTTGCAAAATCGGGCATTTGTTTTTTGGCTTTTTTCTGTG
ATCGTACTCACAAAACTTTA

Product: L-fucose operon activator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 248; Mature: 248

Protein sequence:

>248_residues
MESRHSLIIRYLEEFHQASVLELAEQFNVSVETVRRDLNKLAAEGLLHRTHGGAVSNKQRDVGRSFHVRQRMNSNAKKMI
ADNVIHHLFPEATIALDASSTAWNVAQRIPNIPCKVVSSSMRIIYSLSHKPHIETIATGGVYVEKYNAFYGPLSEQLLSR
LKIDIAIISCTGVADGAIWESNEVNIAFKRKLLANSKQVFLLVDHSKLERKDRFKMADLSEVDKLFVNQLPPQTLQNYCA
QNSIEIVL

Sequences:

>Translated_248_residues
MESRHSLIIRYLEEFHQASVLELAEQFNVSVETVRRDLNKLAAEGLLHRTHGGAVSNKQRDVGRSFHVRQRMNSNAKKMI
ADNVIHHLFPEATIALDASSTAWNVAQRIPNIPCKVVSSSMRIIYSLSHKPHIETIATGGVYVEKYNAFYGPLSEQLLSR
LKIDIAIISCTGVADGAIWESNEVNIAFKRKLLANSKQVFLLVDHSKLERKDRFKMADLSEVDKLFVNQLPPQTLQNYCA
QNSIEIVL
>Mature_248_residues
MESRHSLIIRYLEEFHQASVLELAEQFNVSVETVRRDLNKLAAEGLLHRTHGGAVSNKQRDVGRSFHVRQRMNSNAKKMI
ADNVIHHLFPEATIALDASSTAWNVAQRIPNIPCKVVSSSMRIIYSLSHKPHIETIATGGVYVEKYNAFYGPLSEQLLSR
LKIDIAIISCTGVADGAIWESNEVNIAFKRKLLANSKQVFLLVDHSKLERKDRFKMADLSEVDKLFVNQLPPQTLQNYCA
QNSIEIVL

Specific function: Transcriptional activator of the fuc operon [H]

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789170, Length=210, Percent_Identity=36.1904761904762, Blast_Score=138, Evalue=4e-34,
Organism=Escherichia coli, GI87082344, Length=249, Percent_Identity=28.5140562248996, Blast_Score=118, Evalue=4e-28,
Organism=Escherichia coli, GI1789829, Length=247, Percent_Identity=29.1497975708502, Blast_Score=114, Evalue=8e-27,
Organism=Escherichia coli, GI1788069, Length=236, Percent_Identity=30.5084745762712, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1789059, Length=250, Percent_Identity=27.6, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1790753, Length=241, Percent_Identity=24.896265560166, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI1789519, Length=250, Percent_Identity=22.4, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI226510968, Length=232, Percent_Identity=26.7241379310345, Blast_Score=73, Evalue=1e-14,
Organism=Escherichia coli, GI1790635, Length=241, Percent_Identity=21.9917012448133, Blast_Score=67, Evalue=9e-13,
Organism=Escherichia coli, GI1787540, Length=176, Percent_Identity=31.8181818181818, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787063, Length=256, Percent_Identity=27.34375, Blast_Score=65, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 28007; Mature: 28007

Theoretical pI: Translated: 9.11; Mature: 9.11

Prosite motif: PS00894 HTH_DEOR_1 ; PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESRHSLIIRYLEEFHQASVLELAEQFNVSVETVRRDLNKLAAEGLLHRTHGGAVSNKQR
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHH
DVGRSFHVRQRMNSNAKKMIADNVIHHLFPEATIALDASSTAWNVAQRIPNIPCKVVSSS
HHCHHHHHHHHHCCCHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHCCCCCHHHHHHH
MRIIYSLSHKPHIETIATGGVYVEKYNAFYGPLSEQLLSRLKIDIAIISCTGVADGAIWE
HHEEEECCCCCCCEEEECCCEEEEECCCCCCCHHHHHHHHHHHEEEEEEECCCCCCCEEC
SNEVNIAFKRKLLANSKQVFLLVDHSKLERKDRFKMADLSEVDKLFVNQLPPQTLQNYCA
CCCCCHHHHHHHHCCCCEEEEEECCHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHC
QNSIEIVL
CCCEEEEC
>Mature Secondary Structure
MESRHSLIIRYLEEFHQASVLELAEQFNVSVETVRRDLNKLAAEGLLHRTHGGAVSNKQR
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHH
DVGRSFHVRQRMNSNAKKMIADNVIHHLFPEATIALDASSTAWNVAQRIPNIPCKVVSSS
HHCHHHHHHHHHCCCHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHCCCCCHHHHHHH
MRIIYSLSHKPHIETIATGGVYVEKYNAFYGPLSEQLLSRLKIDIAIISCTGVADGAIWE
HHEEEECCCCCCCEEEECCCEEEEECCCCCCCHHHHHHHHHHHEEEEEEECCCCCCCEEC
SNEVNIAFKRKLLANSKQVFLLVDHSKLERKDRFKMADLSEVDKLFVNQLPPQTLQNYCA
CCCCCHHHHHHHHCCCCEEEEEECCHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHC
QNSIEIVL
CCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]