Definition Actinobacillus pleuropneumoniae serovar 5b str. L20 chromosome, complete genome.
Accession NC_009053
Length 2,274,482

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The map label for this gene is cbiO [C]

Identifier: 126209084

GI number: 126209084

Start: 1844688

End: 1845317

Strand: Reverse

Name: cbiO [C]

Synonym: APL_1620

Alternate gene names: 126209084

Gene position: 1845317-1844688 (Counterclockwise)

Preceding gene: 126209085

Following gene: 126209083

Centisome position: 81.13

GC content: 40.48

Gene sequence:

>630_bases
ATGAATATACTGACAGTCCGCAATCTTACTATTTGCCGTAATCAACAGCCTATTATCGAAAACCTCAGTTTTACCCTCGA
AGCTCAACAGTGTTTATTTCTACAAGGTGAAATCGGTGCGGGTAAATCGACATTACTGCTTTCTTTATTGGGATTCGTAC
CGATTCAATCGGGAGAGATATCTTTATTCGGCAAAAGGTGTAAAATTGAAAAAGATTTTGCGCCGTTTAGGGGAACGATC
GGCTTGTGTTTCCAAAATGCGGAAGATCAATTATTCGGCCCTACGGTATTGGATGATGTGGCATTCGGCGTATTAAATCA
AGGCTACACAAGAGCGGAAGCCTATCATATCGCCCTTACGCAGTTGGAACAAATCGGTATTGCTCACCTAAAAGACCGTC
CGGTCAATTTACTCTCCGGCGGAGAAAAAAATTTTACCGCATTAGCCGGCGTATTGGCGATGCAACCTAAAATGTTATTA
CTTGATGAGCCGACAAACGGGCTTGATGCAAAAAATTGTGAAAAATTAACCGCTTTACTCAAACAATTAAAATTGCCGAT
GTTAATTGCTTCACATGATCAAACCTTTTGTCGAACACTCGCAACAGATACGCTTTATTTAACAAAATAA

Upstream 100 bases:

>100_bases
TTGATTCATGCGATGGTAAGGGCGGAAAAAGCCGAAATCGCTTTAAAAGCCCGCGGATTTAAATTTGGTGAAAAATAGCC
CTGCAAATAAGAATACATAA

Downstream 100 bases:

>100_bases
ACCACAAAATAGTGGTGCAAACACACGGGAATGAAAAATGAAGCTGCTTAAATCCACCCTTACCGGGGTAGGGCAAATCT
TTTTACAAGAAAACGGGTGA

Product: ABC transporter ATP-binding protein

Products: taurine [Cytoplasm]; ADP; phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 209; Mature: 209

Protein sequence:

>209_residues
MNILTVRNLTICRNQQPIIENLSFTLEAQQCLFLQGEIGAGKSTLLLSLLGFVPIQSGEISLFGKRCKIEKDFAPFRGTI
GLCFQNAEDQLFGPTVLDDVAFGVLNQGYTRAEAYHIALTQLEQIGIAHLKDRPVNLLSGGEKNFTALAGVLAMQPKMLL
LDEPTNGLDAKNCEKLTALLKQLKLPMLIASHDQTFCRTLATDTLYLTK

Sequences:

>Translated_209_residues
MNILTVRNLTICRNQQPIIENLSFTLEAQQCLFLQGEIGAGKSTLLLSLLGFVPIQSGEISLFGKRCKIEKDFAPFRGTI
GLCFQNAEDQLFGPTVLDDVAFGVLNQGYTRAEAYHIALTQLEQIGIAHLKDRPVNLLSGGEKNFTALAGVLAMQPKMLL
LDEPTNGLDAKNCEKLTALLKQLKLPMLIASHDQTFCRTLATDTLYLTK
>Mature_209_residues
MNILTVRNLTICRNQQPIIENLSFTLEAQQCLFLQGEIGAGKSTLLLSLLGFVPIQSGEISLFGKRCKIEKDFAPFRGTI
GLCFQNAEDQLFGPTVLDDVAFGVLNQGYTRAEAYHIALTQLEQIGIAHLKDRPVNLLSGGEKNFTALAGVLAMQPKMLL
LDEPTNGLDAKNCEKLTALLKQLKLPMLIASHDQTFCRTLATDTLYLTK

Specific function: Part Of A Binding-Protein-Dependent Transport System For Taurine. Probably Responsible For Energy Coupling To The Transport System. [C]

COG id: COG1122

COG function: function code P; ABC-type cobalt transport system, ATPase component

Gene ontology:

Cell location: Inner Membrane-Associated [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI9955963, Length=171, Percent_Identity=32.7485380116959, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI171184400, Length=172, Percent_Identity=31.3953488372093, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI105990541, Length=170, Percent_Identity=29.4117647058824, Blast_Score=66, Evalue=2e-11,
Organism=Homo sapiens, GI116734710, Length=167, Percent_Identity=31.7365269461078, Blast_Score=65, Evalue=3e-11,
Organism=Homo sapiens, GI150417984, Length=208, Percent_Identity=28.8461538461538, Blast_Score=65, Evalue=4e-11,
Organism=Homo sapiens, GI148612853, Length=190, Percent_Identity=33.1578947368421, Blast_Score=64, Evalue=7e-11,
Organism=Homo sapiens, GI27262624, Length=166, Percent_Identity=31.3253012048193, Blast_Score=64, Evalue=7e-11,
Organism=Homo sapiens, GI27262626, Length=166, Percent_Identity=31.3253012048193, Blast_Score=64, Evalue=7e-11,
Organism=Homo sapiens, GI27881501, Length=188, Percent_Identity=28.7234042553192, Blast_Score=64, Evalue=8e-11,
Organism=Homo sapiens, GI30795238, Length=188, Percent_Identity=28.7234042553192, Blast_Score=64, Evalue=9e-11,
Organism=Escherichia coli, GI1786563, Length=210, Percent_Identity=34.7619047619048, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI87081791, Length=207, Percent_Identity=33.3333333333333, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1787712, Length=182, Percent_Identity=29.6703296703297, Blast_Score=88, Evalue=5e-19,
Organism=Escherichia coli, GI1788761, Length=215, Percent_Identity=31.6279069767442, Blast_Score=86, Evalue=1e-18,
Organism=Escherichia coli, GI1786872, Length=214, Percent_Identity=28.5046728971963, Blast_Score=82, Evalue=2e-17,
Organism=Escherichia coli, GI1787029, Length=198, Percent_Identity=29.7979797979798, Blast_Score=81, Evalue=4e-17,
Organism=Escherichia coli, GI1788225, Length=219, Percent_Identity=29.2237442922374, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI87081709, Length=217, Percent_Identity=29.4930875576037, Blast_Score=78, Evalue=4e-16,
Organism=Escherichia coli, GI1789672, Length=213, Percent_Identity=26.7605633802817, Blast_Score=77, Evalue=6e-16,
Organism=Escherichia coli, GI1790467, Length=213, Percent_Identity=28.6384976525822, Blast_Score=75, Evalue=2e-15,
Organism=Escherichia coli, GI1786703, Length=205, Percent_Identity=31.7073170731707, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI1788506, Length=221, Percent_Identity=31.2217194570136, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI87081834, Length=194, Percent_Identity=30.4123711340206, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1789593, Length=198, Percent_Identity=30.3030303030303, Blast_Score=72, Evalue=2e-14,
Organism=Escherichia coli, GI1789873, Length=181, Percent_Identity=30.3867403314917, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1786319, Length=169, Percent_Identity=32.5443786982249, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI145693107, Length=233, Percent_Identity=29.1845493562232, Blast_Score=68, Evalue=4e-13,
Organism=Escherichia coli, GI1787143, Length=187, Percent_Identity=28.8770053475936, Blast_Score=66, Evalue=1e-12,
Organism=Escherichia coli, GI1790544, Length=198, Percent_Identity=27.7777777777778, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1786253, Length=215, Percent_Identity=29.7674418604651, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1787089, Length=188, Percent_Identity=28.7234042553192, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1786698, Length=197, Percent_Identity=28.9340101522843, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1787370, Length=196, Percent_Identity=28.5714285714286, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI87082267, Length=198, Percent_Identity=29.7979797979798, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1786803, Length=180, Percent_Identity=31.6666666666667, Blast_Score=63, Evalue=1e-11,
Organism=Escherichia coli, GI1788053, Length=201, Percent_Identity=29.8507462686567, Blast_Score=61, Evalue=6e-11,
Organism=Escherichia coli, GI1786398, Length=188, Percent_Identity=28.7234042553192, Blast_Score=61, Evalue=6e-11,
Organism=Escherichia coli, GI1788210, Length=168, Percent_Identity=29.7619047619048, Blast_Score=61, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI25146777, Length=190, Percent_Identity=31.0526315789474, Blast_Score=73, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI212646699, Length=164, Percent_Identity=30.4878048780488, Blast_Score=67, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI193211017, Length=176, Percent_Identity=30.1136363636364, Blast_Score=65, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71996809, Length=176, Percent_Identity=30.1136363636364, Blast_Score=65, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI193211015, Length=176, Percent_Identity=30.1136363636364, Blast_Score=65, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6323959, Length=188, Percent_Identity=30.3191489361702, Blast_Score=65, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6325030, Length=176, Percent_Identity=34.0909090909091, Blast_Score=64, Evalue=2e-11,
Organism=Drosophila melanogaster, GI116007328, Length=177, Percent_Identity=30.5084745762712, Blast_Score=75, Evalue=2e-14,
Organism=Drosophila melanogaster, GI28574150, Length=177, Percent_Identity=30.5084745762712, Blast_Score=75, Evalue=2e-14,
Organism=Drosophila melanogaster, GI19920532, Length=173, Percent_Identity=32.3699421965318, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24580930, Length=173, Percent_Identity=32.3699421965318, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI28574533, Length=185, Percent_Identity=30.8108108108108, Blast_Score=68, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24641565, Length=174, Percent_Identity=29.8850574712644, Blast_Score=64, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 22997; Mature: 22997

Theoretical pI: Translated: 6.75; Mature: 6.75

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure: 

>Translated Secondary Structure
MNILTVRNLTICRNQQPIIENLSFTLEAQQCLFLQGEIGAGKSTLLLSLLGFVPIQSGEI
CCEEEEECEEEECCCCCHHHCCEEEEEECEEEEEECCCCCCHHHHHHHHHHHCCCCCCCE
SLFGKRCKIEKDFAPFRGTIGLCFQNAEDQLFGPTVLDDVAFGVLNQGYTRAEAYHIALT
EEEECEECCCCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHH
QLEQIGIAHLKDRPVNLLSGGEKNFTALAGVLAMQPKMLLLDEPTNGLDAKNCEKLTALL
HHHHHCHHHCCCCCCHHHCCCCCCHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHH
KQLKLPMLIASHDQTFCRTLATDTLYLTK
HHHCCCEEEECCCHHHHHHHHCCEEEEEC
>Mature Secondary Structure
MNILTVRNLTICRNQQPIIENLSFTLEAQQCLFLQGEIGAGKSTLLLSLLGFVPIQSGEI
CCEEEEECEEEECCCCCHHHCCEEEEEECEEEEEECCCCCCHHHHHHHHHHHCCCCCCCE
SLFGKRCKIEKDFAPFRGTIGLCFQNAEDQLFGPTVLDDVAFGVLNQGYTRAEAYHIALT
EEEECEECCCCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHH
QLEQIGIAHLKDRPVNLLSGGEKNFTALAGVLAMQPKMLLLDEPTNGLDAKNCEKLTALL
HHHHHCHHHCCCCCCHHHCCCCCCHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHH
KQLKLPMLIASHDQTFCRTLATDTLYLTK
HHHCCCEEEECCCHHHHHHHHCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: taurine [Periplasm]; ATP; H2O [C]

Specific reaction: taurine [Periplasm] + ATP + H2O = taurine [Cytoplasm] + ADP + phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]