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The map label for this gene is ureD

Identifier: 126209075

GI number: 126209075

Start: 1837396

End: 1838208

Strand: Reverse

Name: ureD

Synonym: APL_1611

Alternate gene names: 126209075

Gene position: 1838208-1837396 (Counterclockwise)

Preceding gene: 126209076

Following gene: 126209074

Centisome position: 80.82

GC content: 43.91

Gene sequence:

>813_bases
ATGCAAAGCAAACTTTTACTCTCAACAAAATTAACCTCACAGGGCAAAACGCAGCTCGATCAATATTTTGTGTCGCCGCC
GTTTAAAGTGATGACCTTGCCTGCTTATGACGATGCTTGGCAAAACGGTTTGAATGCGATGCAAATGTCGTCCTCGCCCG
GTTTGTTGGCAGGTGATCTGCTTGATATTGAGATTTCACTGGCAGACAATACCGCACTTTCGTTGAATACGCAGGCGTTT
ACTCGTGTGCAATCAATGAATGAGGGCGATTATGCCACGCAAAAAACTTGCATAAAATTGGGCAAAAATAGCCGCTTGTT
TTATCTTCCGCACCCATTGGTGCTACATAAAGACAGCGGATTTAAGCAAACTACCGAAATTGAGATGAGCGAGCAGTCCG
AGCTGATTTACGGCGAGATTGTGGCGATTGGGCGAGTGCTAAACGGCGAACGATTCGCCTTCCGTCATTTTGCGTCCTAT
TTGCGAATTTCTTACCAAAATCAACCGCTTGTTACCGACCGTATTCAGTGGCTACCGGCAAAAATGGCATTGACGTCATT
GAGCCAAATGGAAGATTTTTCACATCAAGGCTCTCTCACTTATGTTAATTTGGCAAAAAATGCTGTCGAAATTAAGGCAA
TGGTAAGCGAATTACAAGCTTTAGCCGCCGAGCAAAAAAATATGCTGATTGGCGTTTCGCAGTTGAATGAAGGCGGATTG
ATGGTTCGAGTGCTTGCACATCGAGCGGATATCATTCAACATTTATTTGAGCGGATTGGGCAAGTTTTAAAAGCTCAGTC
CAATATTGTTTAA

Upstream 100 bases:

>100_bases
CGTATTAGAGGGGGATTGGGCGATCCCTACTTTTCTCTAGTTTTCATCCCCCCTCTTTTGTAAAGAGGGGTTGGGGGAGA
TTTTAAAAATAGACTGCAAT

Downstream 100 bases:

>100_bases
TTTAGGAGAGCAATTATGATCGCAGTTTATGCAGTATGCCATGTAAAAGCGGATAAAATCGCAGAATTTGAAGCATTGGC
ACAAAACTTAATTCGTGCTT

Product: urease accessory protein UreD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 270; Mature: 270

Protein sequence:

>270_residues
MQSKLLLSTKLTSQGKTQLDQYFVSPPFKVMTLPAYDDAWQNGLNAMQMSSSPGLLAGDLLDIEISLADNTALSLNTQAF
TRVQSMNEGDYATQKTCIKLGKNSRLFYLPHPLVLHKDSGFKQTTEIEMSEQSELIYGEIVAIGRVLNGERFAFRHFASY
LRISYQNQPLVTDRIQWLPAKMALTSLSQMEDFSHQGSLTYVNLAKNAVEIKAMVSELQALAAEQKNMLIGVSQLNEGGL
MVRVLAHRADIIQHLFERIGQVLKAQSNIV

Sequences:

>Translated_270_residues
MQSKLLLSTKLTSQGKTQLDQYFVSPPFKVMTLPAYDDAWQNGLNAMQMSSSPGLLAGDLLDIEISLADNTALSLNTQAF
TRVQSMNEGDYATQKTCIKLGKNSRLFYLPHPLVLHKDSGFKQTTEIEMSEQSELIYGEIVAIGRVLNGERFAFRHFASY
LRISYQNQPLVTDRIQWLPAKMALTSLSQMEDFSHQGSLTYVNLAKNAVEIKAMVSELQALAAEQKNMLIGVSQLNEGGL
MVRVLAHRADIIQHLFERIGQVLKAQSNIV
>Mature_270_residues
MQSKLLLSTKLTSQGKTQLDQYFVSPPFKVMTLPAYDDAWQNGLNAMQMSSSPGLLAGDLLDIEISLADNTALSLNTQAF
TRVQSMNEGDYATQKTCIKLGKNSRLFYLPHPLVLHKDSGFKQTTEIEMSEQSELIYGEIVAIGRVLNGERFAFRHFASY
LRISYQNQPLVTDRIQWLPAKMALTSLSQMEDFSHQGSLTYVNLAKNAVEIKAMVSELQALAAEQKNMLIGVSQLNEGGL
MVRVLAHRADIIQHLFERIGQVLKAQSNIV

Specific function: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter

COG id: COG0829

COG function: function code O; Urease accessory protein UreH

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ureD family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): URED_ACTP2 (A3N2Q9)

Other databases:

- EMBL:   CP000569
- RefSeq:   YP_001054300.1
- STRING:   A3N2Q9
- GeneID:   4849315
- GenomeReviews:   CP000569_GR
- KEGG:   apl:APL_1611
- eggNOG:   COG0829
- HOGENOM:   HBG296673
- OMA:   SELIYGE
- ProtClustDB:   CLSK892371
- BioCyc:   APLE416269:APL_1611-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01384
- InterPro:   IPR002669

Pfam domain/function: PF01774 UreD

EC number: NA

Molecular weight: Translated: 30142; Mature: 30142

Theoretical pI: Translated: 7.16; Mature: 7.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQSKLLLSTKLTSQGKTQLDQYFVSPPFKVMTLPAYDDAWQNGLNAMQMSSSPGLLAGDL
CCCCEEEEEECCCCCHHHHHHHHCCCCEEEEEECCCCHHHHCCCCEEEECCCCCEEECCE
LDIEISLADNTALSLNTQAFTRVQSMNEGDYATQKTCIKLGKNSRLFYLPHPLVLHKDSG
EEEEEEECCCCEEEECHHHHHHHHHCCCCCHHHHHHHHHHCCCCEEEEECCCEEEECCCC
FKQTTEIEMSEQSELIYGEIVAIGRVLNGERFAFRHFASYLRISYQNQPLVTDRIQWLPA
CCEEEEEECCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHEECCCCCCHHHHHHHHHH
KMALTSLSQMEDFSHQGSLTYVNLAKNAVEIKAMVSELQALAAEQKNMLIGVSQLNEGGL
HHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCE
MVRVLAHRADIIQHLFERIGQVLKAQSNIV
EEHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MQSKLLLSTKLTSQGKTQLDQYFVSPPFKVMTLPAYDDAWQNGLNAMQMSSSPGLLAGDL
CCCCEEEEEECCCCCHHHHHHHHCCCCEEEEEECCCCHHHHCCCCEEEECCCCCEEECCE
LDIEISLADNTALSLNTQAFTRVQSMNEGDYATQKTCIKLGKNSRLFYLPHPLVLHKDSG
EEEEEEECCCCEEEECHHHHHHHHHCCCCCHHHHHHHHHHCCCCEEEEECCCEEEECCCC
FKQTTEIEMSEQSELIYGEIVAIGRVLNGERFAFRHFASYLRISYQNQPLVTDRIQWLPA
CCEEEEEECCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHEECCCCCCHHHHHHHHHH
KMALTSLSQMEDFSHQGSLTYVNLAKNAVEIKAMVSELQALAAEQKNMLIGVSQLNEGGL
HHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCE
MVRVLAHRADIIQHLFERIGQVLKAQSNIV
EEHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA