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The map label for this gene is accA

Identifier: 126208950

GI number: 126208950

Start: 1701093

End: 1702046

Strand: Reverse

Name: accA

Synonym: APL_1486

Alternate gene names: 126208950

Gene position: 1702046-1701093 (Counterclockwise)

Preceding gene: 126208951

Following gene: 126208949

Centisome position: 74.83

GC content: 47.06

Gene sequence:

>954_bases
ATGAGCCAAGAATATTTAGATTTTGAATTACCGATTGCCGAATTGGAAGCGAAAATCGAATCGCTCCGTGCAGTTAGCGA
GCAAGACGGTAAAATCGACCTTGATGACGAAATCAAACGCTTACAGAAAAAAAGCGAAGAACTGACTAAGAAAACCTTTG
CAAACTTAGATGCGTGGCAAGTTTCTCGTATGGCGCGCCATCCGAATCGCCCGTACACTTTAGATTATATCGAGCATATT
TTTACCGAGTTTGACGAACTTGCAGGTGATCGTGCGTTTGCGGATGATAAAGCAATCGTCGGCGGTATTGCACGCCTTGA
CGGACGTCCGGTGATGGTCATCGGCCACCAGAAAGGTCGTACCACCAAAGAAAAAGTAAGACGTAATTTCGGTATGCCGG
CACCGGAAGGCTATCGCAAAGCGTTACGTTTAATGGAAATGGCGGATCGCTTTAATATGCCGATTATTACCTTTATCGAC
ACGCCGGGCGCTTATCCGGGTATCGGTGCGGAAGAACGCGGCCAAGCGGAAGCGATTGCACGCAACTTACGTGAAATGGC
GCAATTAAAAGTGCCGGTTATCTGTACGGTTATCGGTGAAGGCGGTTCAGGCGGTGCTTTAGCGATTGGTGTCGGCGATA
AAGTAAATATGTTGCAATATTCAACCTATTCGGTCATTTCTCCGGAAGGCTGTGCTTCCATTCTTTGGAAAAGCGCCGAA
AAAGCCTCAACCGCGGCGGAAGTTATGGGTTTAACCGCGCAACGTTTAAAAGAATTAAACTTAATCGACAGCATCGTGGC
AGAGCCGCTCGGCGGTGCGCACCGTGATGTGGCGCAAATGGCGGAAAATCTTAAACAACAAATTTTAGCCGATTTACAAG
ACTTAGCTCCGCTCAGTACGGAAGACCTATTAGATCGTCGTTATCAACGTTTAATGAGCTACGGTTACGTATAA

Upstream 100 bases:

>100_bases
CAAAATTTGCAAAAAATTGAAAAAAATAACCGCTTAAATACCTATTTAGCCCGTATCACTGGTAAAATAGATAGAATTTT
CTGAAAATAGGACTTAGACA

Downstream 100 bases:

>100_bases
ACGAAAGAGAAAACACGCGGTCAAATTTTTGTGATTTTTTGCGAAAATTTGATCGCTTTTTTATACACAAAAATCTTAAA
TCGACTATTTTTGAATGGAT

Product: acetyl-CoA carboxylase carboxyltransferase subunit alpha

Products: NA

Alternate protein names: ACCase subunit alpha; Acetyl-CoA carboxylase carboxyltransferase subunit alpha

Number of amino acids: Translated: 317; Mature: 316

Protein sequence:

>317_residues
MSQEYLDFELPIAELEAKIESLRAVSEQDGKIDLDDEIKRLQKKSEELTKKTFANLDAWQVSRMARHPNRPYTLDYIEHI
FTEFDELAGDRAFADDKAIVGGIARLDGRPVMVIGHQKGRTTKEKVRRNFGMPAPEGYRKALRLMEMADRFNMPIITFID
TPGAYPGIGAEERGQAEAIARNLREMAQLKVPVICTVIGEGGSGGALAIGVGDKVNMLQYSTYSVISPEGCASILWKSAE
KASTAAEVMGLTAQRLKELNLIDSIVAEPLGGAHRDVAQMAENLKQQILADLQDLAPLSTEDLLDRRYQRLMSYGYV

Sequences:

>Translated_317_residues
MSQEYLDFELPIAELEAKIESLRAVSEQDGKIDLDDEIKRLQKKSEELTKKTFANLDAWQVSRMARHPNRPYTLDYIEHI
FTEFDELAGDRAFADDKAIVGGIARLDGRPVMVIGHQKGRTTKEKVRRNFGMPAPEGYRKALRLMEMADRFNMPIITFID
TPGAYPGIGAEERGQAEAIARNLREMAQLKVPVICTVIGEGGSGGALAIGVGDKVNMLQYSTYSVISPEGCASILWKSAE
KASTAAEVMGLTAQRLKELNLIDSIVAEPLGGAHRDVAQMAENLKQQILADLQDLAPLSTEDLLDRRYQRLMSYGYV
>Mature_316_residues
SQEYLDFELPIAELEAKIESLRAVSEQDGKIDLDDEIKRLQKKSEELTKKTFANLDAWQVSRMARHPNRPYTLDYIEHIF
TEFDELAGDRAFADDKAIVGGIARLDGRPVMVIGHQKGRTTKEKVRRNFGMPAPEGYRKALRLMEMADRFNMPIITFIDT
PGAYPGIGAEERGQAEAIARNLREMAQLKVPVICTVIGEGGSGGALAIGVGDKVNMLQYSTYSVISPEGCASILWKSAEK
ASTAAEVMGLTAQRLKELNLIDSIVAEPLGGAHRDVAQMAENLKQQILADLQDLAPLSTEDLLDRRYQRLMSYGYV

Specific function: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-Co

COG id: COG0825

COG function: function code I; Acetyl-CoA carboxylase alpha subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AccA family

Homologues:

Organism=Escherichia coli, GI1786382, Length=318, Percent_Identity=78.6163522012579, Blast_Score=518, Evalue=1e-148,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACCA_ACTP2 (A3N2D4)

Other databases:

- EMBL:   CP000569
- RefSeq:   YP_001054175.1
- ProteinModelPortal:   A3N2D4
- SMR:   A3N2D4
- STRING:   A3N2D4
- GeneID:   4849457
- GenomeReviews:   CP000569_GR
- KEGG:   apl:APL_1486
- eggNOG:   COG0825
- HOGENOM:   HBG286557
- OMA:   QLTKDIY
- PhylomeDB:   A3N2D4
- ProtClustDB:   PRK05724
- BioCyc:   APLE416269:APL_1486-MONOMER
- HAMAP:   MF_00823
- InterPro:   IPR001095
- InterPro:   IPR011763
- PANTHER:   PTHR22855:SF3
- PRINTS:   PR01069
- TIGRFAMs:   TIGR00513

Pfam domain/function: PF03255 ACCA

EC number: =6.4.1.2

Molecular weight: Translated: 35192; Mature: 35061

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: PS50989 COA_CT_CTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQEYLDFELPIAELEAKIESLRAVSEQDGKIDLDDEIKRLQKKSEELTKKTFANLDAWQ
CCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHH
VSRMARHPNRPYTLDYIEHIFTEFDELAGDRAFADDKAIVGGIARLDGRPVMVIGHQKGR
HHHHHHCCCCCEEHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCEEEEEECCCCC
TTKEKVRRNFGMPAPEGYRKALRLMEMADRFNMPIITFIDTPGAYPGIGAEERGQAEAIA
CHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCHHHHHH
RNLREMAQLKVPVICTVIGEGGSGGALAIGVGDKVNMLQYSTYSVISPEGCASILWKSAE
HHHHHHHHCCCCEEEEEEECCCCCCEEEEECCCCCCCEEECCCCCCCCHHHHHHHHHHHH
KASTAAEVMGLTAQRLKELNLIDSIVAEPLGGAHRDVAQMAENLKQQILADLQDLAPLST
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCH
EDLLDRRYQRLMSYGYV
HHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SQEYLDFELPIAELEAKIESLRAVSEQDGKIDLDDEIKRLQKKSEELTKKTFANLDAWQ
CCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHH
VSRMARHPNRPYTLDYIEHIFTEFDELAGDRAFADDKAIVGGIARLDGRPVMVIGHQKGR
HHHHHHCCCCCEEHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCEEEEEECCCCC
TTKEKVRRNFGMPAPEGYRKALRLMEMADRFNMPIITFIDTPGAYPGIGAEERGQAEAIA
CHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCHHHHHH
RNLREMAQLKVPVICTVIGEGGSGGALAIGVGDKVNMLQYSTYSVISPEGCASILWKSAE
HHHHHHHHCCCCEEEEEEECCCCCCEEEEECCCCCCCEEECCCCCCCCHHHHHHHHHHHH
KASTAAEVMGLTAQRLKELNLIDSIVAEPLGGAHRDVAQMAENLKQQILADLQDLAPLST
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCH
EDLLDRRYQRLMSYGYV
HHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA