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The map label for this gene is mglB [H]

Identifier: 126208884

GI number: 126208884

Start: 1622513

End: 1623505

Strand: Reverse

Name: mglB [H]

Synonym: APL_1420

Alternate gene names: 126208884

Gene position: 1623505-1622513 (Counterclockwise)

Preceding gene: 126208885

Following gene: 126208883

Centisome position: 71.38

GC content: 41.89

Gene sequence:

>993_bases
ATGAAAAAAACAGTATTAAGTACATTGGCATTATCAATTGCATTAGGTGCGGGTATTAGCACAGCACAAGCCGAAACACG
TATCGGTGTGACAATCTATAAATACGACGATAACTTTATGGCGCTAATGCGTAAAGAAATCGACAAAGAAGCAAGTCAAT
TCAAAGATGTGAAGTTATTAATGAATGACTCGCAAAACACTCAATCCATTCAAAACGACCAAGTGGACGTCTTGCTTTCT
AAAGGCGTAAAAGCGTTAGCAATCAACCTAGTGGACCCTTCAGCGTCAAAAACTATTATCGATAAAGCGAAAGGCGAAGA
TTTACCAATCGTATTCTTCAATAAAGATCCGGGTGAGAAAGCGATTGCCAGCTATGACAAGGCTTACTATGTAGGTACCG
ACCCGAAAGAATCCGGTTTAATCCAAGGCGACTTAATCGCTAAACAATGGAAAGCGAATCCGGCGTTAGACTTAAATAAA
GACGGTAAAGTGCAATATGCGTTATTAAAAGGCGAACCGGGTCACCCTGATGCGGAAGCGCGTACTAAATACGTAGTGGA
AGGCTTAGCGGCACAAGGTATCCAAAGCGAACAAATCTTTATGGATGCGGCATTGTGGGATGCGGCACAAGCGAAAGATA
AAGTGGACGCTTGGTTGTCAAGCGGTAAAGCGAAAGATATTGAAGTGATTATCTCGAATAACGACGGTATGGCGTTAGGT
GCGTTAGAAGCAACTAAAGCGCACGGTCGTAAATTACCGATTTTTGGTGTGGACGCATTACCTGAAGCATTACAATTAGT
TAAAAAAGGCGAATTAGCCGGTACGGTATTAAATGACGGTGCGGGTCAAGGTAAAGCGGTAGTACAATTAGCGGCTAACC
TTGCTGAAGGTAAAGCGGCAGGCGAAGGCACTAATTGGAAAATTGAGAACCGTGTAGTACGTATTCCTTACGTTGGCGTA
GATAAAGATAATTTAGAAAAATTCTTAAAATAA

Upstream 100 bases:

>100_bases
AAAATGATCACAGTATTTTATTCATAAATTTAGTATCCTTATTATGTAATCACTTATATTAAGTGAATCTCTAAATCATT
TGGATCTTGAGGATAACTCT

Downstream 100 bases:

>100_bases
TTGACTCGATGAGGCACGAGTAGGCTACTCGTGCCTTTTTTATCGGTATTATGGAGTGAGATATGACAAGTGAAGTACTG
CTCACAATGACAAATGTTAG

Product: D-galactose-binding periplasmic protein precursor

Products: ADP; phosphate; beta-D-galactose [Cytoplasm] [C]

Alternate protein names: GBP; D-galactose/ D-glucose-binding protein; GGBP [H]

Number of amino acids: Translated: 330; Mature: 330

Protein sequence:

>330_residues
MKKTVLSTLALSIALGAGISTAQAETRIGVTIYKYDDNFMALMRKEIDKEASQFKDVKLLMNDSQNTQSIQNDQVDVLLS
KGVKALAINLVDPSASKTIIDKAKGEDLPIVFFNKDPGEKAIASYDKAYYVGTDPKESGLIQGDLIAKQWKANPALDLNK
DGKVQYALLKGEPGHPDAEARTKYVVEGLAAQGIQSEQIFMDAALWDAAQAKDKVDAWLSSGKAKDIEVIISNNDGMALG
ALEATKAHGRKLPIFGVDALPEALQLVKKGELAGTVLNDGAGQGKAVVQLAANLAEGKAAGEGTNWKIENRVVRIPYVGV
DKDNLEKFLK

Sequences:

>Translated_330_residues
MKKTVLSTLALSIALGAGISTAQAETRIGVTIYKYDDNFMALMRKEIDKEASQFKDVKLLMNDSQNTQSIQNDQVDVLLS
KGVKALAINLVDPSASKTIIDKAKGEDLPIVFFNKDPGEKAIASYDKAYYVGTDPKESGLIQGDLIAKQWKANPALDLNK
DGKVQYALLKGEPGHPDAEARTKYVVEGLAAQGIQSEQIFMDAALWDAAQAKDKVDAWLSSGKAKDIEVIISNNDGMALG
ALEATKAHGRKLPIFGVDALPEALQLVKKGELAGTVLNDGAGQGKAVVQLAANLAEGKAAGEGTNWKIENRVVRIPYVGV
DKDNLEKFLK
>Mature_330_residues
MKKTVLSTLALSIALGAGISTAQAETRIGVTIYKYDDNFMALMRKEIDKEASQFKDVKLLMNDSQNTQSIQNDQVDVLLS
KGVKALAINLVDPSASKTIIDKAKGEDLPIVFFNKDPGEKAIASYDKAYYVGTDPKESGLIQGDLIAKQWKANPALDLNK
DGKVQYALLKGEPGHPDAEARTKYVVEGLAAQGIQSEQIFMDAALWDAAQAKDKVDAWLSSGKAKDIEVIISNNDGMALG
ALEATKAHGRKLPIFGVDALPEALQLVKKGELAGTVLNDGAGQGKAVVQLAANLAEGKAAGEGTNWKIENRVVRIPYVGV
DKDNLEKFLK

Specific function: This protein is involved in the active transport of galactose and glucose [H]

COG id: COG1879

COG function: function code G; ABC-type sugar transport system, periplasmic component

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 2 family [H]

Homologues:

Organism=Escherichia coli, GI1788473, Length=331, Percent_Identity=65.558912386707, Blast_Score=449, Evalue=1e-127,
Organism=Escherichia coli, GI1790192, Length=279, Percent_Identity=27.2401433691756, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: 4720 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 1320 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001761 [H]

Pfam domain/function: PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 35440; Mature: 35440

Theoretical pI: Translated: 5.56; Mature: 5.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKTVLSTLALSIALGAGISTAQAETRIGVTIYKYDDNFMALMRKEIDKEASQFKDVKLL
CCHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEEECCHHHHHHHHHHHHHHHHHHHEEEE
MNDSQNTQSIQNDQVDVLLSKGVKALAINLVDPSASKTIIDKAKGEDLPIVFFNKDPGEK
ECCCCCCHHHCCCCHHHHHHCCCEEEEEEEECCCCCCHHHHHCCCCCCCEEEECCCCCHH
AIASYDKAYYVGTDPKESGLIQGDLIAKQWKANPALDLNKDGKVQYALLKGEPGHPDAEA
HHHHCCCEEEECCCCCCCCCEEHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCCCCHHH
RTKYVVEGLAAQGIQSEQIFMDAALWDAAQAKDKVDAWLSSGKAKDIEVIISNNDGMALG
HHHHHHHHHHHCCCCCHHEEHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCEEEE
ALEATKAHGRKLPIFGVDALPEALQLVKKGELAGTVLNDGAGQGKAVVQLAANLAEGKAA
EEHHHHHCCCCCCEEECHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHHCCCCC
GEGTNWKIENRVVRIPYVGVDKDNLEKFLK
CCCCCEEECCEEEEEEEECCCHHHHHHHCC
>Mature Secondary Structure
MKKTVLSTLALSIALGAGISTAQAETRIGVTIYKYDDNFMALMRKEIDKEASQFKDVKLL
CCHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEEECCHHHHHHHHHHHHHHHHHHHEEEE
MNDSQNTQSIQNDQVDVLLSKGVKALAINLVDPSASKTIIDKAKGEDLPIVFFNKDPGEK
ECCCCCCHHHCCCCHHHHHHCCCEEEEEEEECCCCCCHHHHHCCCCCCCEEEECCCCCHH
AIASYDKAYYVGTDPKESGLIQGDLIAKQWKANPALDLNKDGKVQYALLKGEPGHPDAEA
HHHHCCCEEEECCCCCCCCCEEHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCCCCHHH
RTKYVVEGLAAQGIQSEQIFMDAALWDAAQAKDKVDAWLSSGKAKDIEVIISNNDGMALG
HHHHHHHHHHHCCCCCHHEEHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCEEEE
ALEATKAHGRKLPIFGVDALPEALQLVKKGELAGTVLNDGAGQGKAVVQLAANLAEGKAA
EEHHHHHCCCCCCEEECHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHHCCCCC
GEGTNWKIENRVVRIPYVGVDKDNLEKFLK
CCCCCEEECCEEEEEEEECCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; beta-D-galactose [Periplasm]; H2O [C]

Specific reaction: ATP + beta-D-galactose [Periplasm] + H2O = ADP + phosphate + beta-D-galactose [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800; 10675023 [H]