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The map label for this gene is hslO

Identifier: 126208779

GI number: 126208779

Start: 1505774

End: 1506664

Strand: Direct

Name: hslO

Synonym: APL_1315

Alternate gene names: 126208779

Gene position: 1505774-1506664 (Clockwise)

Preceding gene: 126208778

Following gene: 126208781

Centisome position: 66.2

GC content: 43.55

Gene sequence:

>891_bases
ATGAGTTATACAAAAGACAACGACAAGCTTTATCGCTATTTATTCCAAAACCGTGCCGTGCGCGGCGAATGGGTTCGTTT
AAACGATACCTTTACCGAAACGCTGAATACCCACCAATATCCGAAAGCGGTACAAAATTTATTAGGCGAAATGTTGGTCG
CAACCAGCCTACTTACTGCGATTATGAAATTTGAAGGAACGATTACCGTCCAAATTCAAGGTGACGGTCCGCTCAAATTA
GCGGTGGTAAACGGTAATGAAAAACAACAGTTACGTGCATTAGCGCGTACTCAAGCGGAAATTGCCGATAATGCGAGCTT
AAGCGAAATGATCGGCAACGGCGTATTGGTCATTTCGATTATGCCGAATGACGGCGAACGTTACCAAGGGGTGATCGCGT
TAGATAAACCGACTATTCGTGAATGTTTGGAAGATTATTTTATTCGTTCCGAACAGCTTCAAACGCATTTAGTGATTCGT
ACCGGCGAATATGAAGGTAAAGCGGTTGCCGGCGGTTTATTATTACAAATTATGCCGGACGGTACGGGTACGCCGGAAGA
TTTCGAGCATTTAATGACGCTTGCCGAAACGGTGAAAGACGAAGAATTATTCGGCTTAGAAGCGGAAGAACTTTTATTCC
GTCTATATCACGAAGAACAGGTTGAAGTCTATCCGCCGCAAGAGACCGAATTCCATTGCGGCTGTTCCCGCGGACGTTCG
GGTAATGCGATTTTATTGTTACCGATGGAAGAAATCGATGAAATGCTTGCCGAGAAAAACGGTGTCATCGATATGCAATG
CGAATGCTGCGGCACGCAATATTTCTTTGATAAAAACGCCATTATGGAATTTAAACAAGAAGCGGATAAACTCAATCAAT
TAGGTTTATAA

Upstream 100 bases:

>100_bases
TTTGACGGCACACAGTTTACGGTGTGCCTTCTTTTATTTTAACAAGCGGTCAAATTTGTACATTTTTTTGCAAATCACAC
CGCTTTCATTAGGAAAAACC

Downstream 100 bases:

>100_bases
CGCAAAAAATAAGCGGTTCGATTTTGTATAAATTTTACTAAATCGAACCGCTTACTTTATTGAGTCATTAAATCAGAATA
TTTGCTAATGCAATACCCAC

Product: Hsp33-like chaperonin

Products: NA

Alternate protein names: Heat shock protein 33 homolog; HSP33

Number of amino acids: Translated: 296; Mature: 295

Protein sequence:

>296_residues
MSYTKDNDKLYRYLFQNRAVRGEWVRLNDTFTETLNTHQYPKAVQNLLGEMLVATSLLTAIMKFEGTITVQIQGDGPLKL
AVVNGNEKQQLRALARTQAEIADNASLSEMIGNGVLVISIMPNDGERYQGVIALDKPTIRECLEDYFIRSEQLQTHLVIR
TGEYEGKAVAGGLLLQIMPDGTGTPEDFEHLMTLAETVKDEELFGLEAEELLFRLYHEEQVEVYPPQETEFHCGCSRGRS
GNAILLLPMEEIDEMLAEKNGVIDMQCECCGTQYFFDKNAIMEFKQEADKLNQLGL

Sequences:

>Translated_296_residues
MSYTKDNDKLYRYLFQNRAVRGEWVRLNDTFTETLNTHQYPKAVQNLLGEMLVATSLLTAIMKFEGTITVQIQGDGPLKL
AVVNGNEKQQLRALARTQAEIADNASLSEMIGNGVLVISIMPNDGERYQGVIALDKPTIRECLEDYFIRSEQLQTHLVIR
TGEYEGKAVAGGLLLQIMPDGTGTPEDFEHLMTLAETVKDEELFGLEAEELLFRLYHEEQVEVYPPQETEFHCGCSRGRS
GNAILLLPMEEIDEMLAEKNGVIDMQCECCGTQYFFDKNAIMEFKQEADKLNQLGL
>Mature_295_residues
SYTKDNDKLYRYLFQNRAVRGEWVRLNDTFTETLNTHQYPKAVQNLLGEMLVATSLLTAIMKFEGTITVQIQGDGPLKLA
VVNGNEKQQLRALARTQAEIADNASLSEMIGNGVLVISIMPNDGERYQGVIALDKPTIRECLEDYFIRSEQLQTHLVIRT
GEYEGKAVAGGLLLQIMPDGTGTPEDFEHLMTLAETVKDEELFGLEAEELLFRLYHEEQVEVYPPQETEFHCGCSRGRSG
NAILLLPMEEIDEMLAEKNGVIDMQCECCGTQYFFDKNAIMEFKQEADKLNQLGL

Specific function: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress

COG id: COG1281

COG function: function code O; Disulfide bond chaperones of the HSP33 family

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HSP33 family

Homologues:

Organism=Escherichia coli, GI87082260, Length=282, Percent_Identity=56.0283687943262, Blast_Score=335, Evalue=3e-93,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HSLO_ACTP2 (A3N1W3)

Other databases:

- EMBL:   CP000569
- RefSeq:   YP_001054004.1
- ProteinModelPortal:   A3N1W3
- SMR:   A3N1W3
- STRING:   A3N1W3
- GeneID:   4849060
- GenomeReviews:   CP000569_GR
- KEGG:   apl:APL_1315
- eggNOG:   COG1281
- HOGENOM:   HBG296531
- OMA:   AMTIDQG
- PhylomeDB:   A3N1W3
- ProtClustDB:   PRK00114
- BioCyc:   APLE416269:APL_1315-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00117
- InterPro:   IPR000397
- InterPro:   IPR016154
- InterPro:   IPR016153
- InterPro:   IPR023212
- Gene3D:   G3DSA:1.10.287.480
- Gene3D:   G3DSA:3.90.1280.10
- Gene3D:   G3DSA:3.55.30.10
- PIRSF:   PIRSF005261

Pfam domain/function: PF01430 HSP33; SSF64397 Heat_shock_Hsp33_N

EC number: NA

Molecular weight: Translated: 33416; Mature: 33284

Theoretical pI: Translated: 4.31; Mature: 4.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYTKDNDKLYRYLFQNRAVRGEWVRLNDTFTETLNTHQYPKAVQNLLGEMLVATSLLTA
CCCCCCHHHHHHHHHHCCCCCCCEEEECCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
IMKFEGTITVQIQGDGPLKLAVVNGNEKQQLRALARTQAEIADNASLSEMIGNGVLVISI
HHHCCCEEEEEEECCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCHHHHHHCCCEEEEEE
MPNDGERYQGVIALDKPTIRECLEDYFIRSEQLQTHLVIRTGEYEGKAVAGGLLLQIMPD
ECCCCCCEEEEEEECCHHHHHHHHHHHHCHHCCEEEEEEEECCCCCCEEECEEEEEEECC
GTGTPEDFEHLMTLAETVKDEELFGLEAEELLFRLYHEEQVEVYPPQETEFHCGCSRGRS
CCCCHHHHHHHHHHHHHHCCHHHCCCCHHHHHHHHHCCCCEEEECCCCCCEECCCCCCCC
GNAILLLPMEEIDEMLAEKNGVIDMQCECCGTQYFFDKNAIMEFKQEADKLNQLGL
CCEEEEEEHHHHHHHHHHCCCEEEEEEEECCCEEEECCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SYTKDNDKLYRYLFQNRAVRGEWVRLNDTFTETLNTHQYPKAVQNLLGEMLVATSLLTA
CCCCCHHHHHHHHHHCCCCCCCEEEECCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
IMKFEGTITVQIQGDGPLKLAVVNGNEKQQLRALARTQAEIADNASLSEMIGNGVLVISI
HHHCCCEEEEEEECCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCHHHHHHCCCEEEEEE
MPNDGERYQGVIALDKPTIRECLEDYFIRSEQLQTHLVIRTGEYEGKAVAGGLLLQIMPD
ECCCCCCEEEEEEECCHHHHHHHHHHHHCHHCCEEEEEEEECCCCCCEEECEEEEEEECC
GTGTPEDFEHLMTLAETVKDEELFGLEAEELLFRLYHEEQVEVYPPQETEFHCGCSRGRS
CCCCHHHHHHHHHHHHHHCCHHHCCCCHHHHHHHHHCCCCEEEECCCCCCEECCCCCCCC
GNAILLLPMEEIDEMLAEKNGVIDMQCECCGTQYFFDKNAIMEFKQEADKLNQLGL
CCEEEEEEHHHHHHHHHHCCCEEEEEEEECCCEEEECCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA